Page last updated: 2024-10-28

ibuprofen and Hemophilia A

ibuprofen has been researched along with Hemophilia A in 9 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Hemophilia A: The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.

Research Excerpts

ExcerptRelevanceReference
" Ibuprofen should be considered as a safe and potentially beneficial antiinflammatory agent in the treatment of carefully monitored hemophiliacs eligible for such therapy."2.65The use and safety of Ibuprofen in the hemophiliac. ( Inwood, MJ; Killackey, B; Startup, SJ, 1983)
" We conclude that ibuprofen represents a relatively safe agent for the management of discomfort caused by hemophilic arthropathy in a select group of hemophilic patients."2.65Efficacy and safety of ibuprofen for hemophilic arthropathy. ( Hasiba, U; Lewis, JH; Scranton, PE; Spero, JA, 1980)
"Bleeding times were performed on 71 hemophiliacs using the Simplate II device."1.26The bleeding time is longer than normal in hemophilia. ( Ballard, JO; Eyster, ME; Gordon, RA, 1981)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inwood, MJ2
Killackey, B1
Startup, SJ1
Eyster, ME1
Gordon, RA1
Ballard, JO1
Hasiba, U1
Scranton, PE1
Lewis, JH1
Spero, JA1
Thomas, P1
Hepburn, B1
Kim, HC1
Saidi, P1
Haire, WD1
Cagnoni, PJ1
Aledort, L1
McIntyre, BA1
Philp, RB1
Ragni, MV1
Miller, BJ1
Whalen, R1
Ptachcinski, R1
Steven, MM1
Small, M1
Pinkerton, L1
Madhok, R1
Sturrock, RD1
Forbes, CD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Bleeding Tendency, Platelet Function, and Pharmacokinetics of Azidothymidine (AZT) and Motrin (Ibuprofen) in HIV-Infected Hemophiliacs[NCT00002276]0 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for ibuprofen and Hemophilia A

ArticleYear
The use and safety of Ibuprofen in the hemophiliac.
    Blood, 1983, Volume: 61, Issue:4

    Topics: Adolescent; Adult; Clinical Trials as Topic; Hemophilia A; Humans; Ibuprofen; Joint Diseases; Random

1983
Efficacy and safety of ibuprofen for hemophilic arthropathy.
    Archives of internal medicine, 1980, Volume: 140, Issue:12

    Topics: Ankle Joint; Bleeding Time; Clinical Trials as Topic; Double-Blind Method; Elbow Joint; Hemarthrosis

1980
Nonsteroidal anti-inflammatory drugs in the treatment of hemophilic arthropathy.
    American journal of hematology, 1982, Volume: 12, Issue:2

    Topics: Adult; Aged; Anti-Inflammatory Agents; Bleeding Time; Choline; Glucocorticoids; Hemarthrosis; Hemoph

1982
Effect of ibuprofen on platelet function in normal subjects and hemophiliac patients.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Blood Coagulation; Blood Platelets; Female; Hemophilia A; Humans; Ibuprofen; In V

1978
Non-steroidal anti-inflammatory drugs in haemophilic arthritis. A clinical and laboratory study.
    Haemostasis, 1985, Volume: 15, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis; Blood Platelets; Clinical Trials as Topic; Hemophi

1985

Other Studies

4 other studies available for ibuprofen and Hemophilia A

ArticleYear
The bleeding time is longer than normal in hemophilia.
    Blood, 1981, Volume: 58, Issue:4

    Topics: Adolescent; Adult; Aged; Bleeding Time; Child; Child, Preschool; Factor VIII; Hemophilia A; Humans;

1981
Hemophilic osteoarthropathy.
    Archives of internal medicine, 1982, Volume: 142, Issue:5

    Topics: Analgesics; Bone Diseases; Hemophilia A; Humans; Ibuprofen; Joint Diseases; Tolmetin

1982
Gastrointestinal bleeding in hemophilia as a complication of the use of over the counter non-steroidal anti-inflammatory drugs.
    American journal of hematology, 1994, Volume: 47, Issue:4

    Topics: Gastrointestinal Hemorrhage; Hemophilia A; Humans; Ibuprofen; Male; Middle Aged

1994
Bleeding tendency, platelet function, and pharmacokinetics of ibuprofen and zidovudine in HIV(+) hemophilic men.
    American journal of hematology, 1992, Volume: 40, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Bleeding Time; Blood Platelets; Chronic Disease; Drug Therapy, Com

1992