ibuprofen has been researched along with Headache, Tension in 19 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Excerpt | Relevance | Reference |
---|---|---|
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache." | 9.12 | Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007) |
"Simple analgesics such as ibuprofen, aspirin, and acetaminophen have long been used in the treatment of tension-type headache." | 9.09 | The use of ibuprofen plus caffeine to treat tension-type headache. ( Diamond, S; Freitag, FG, 2001) |
"The safety and efficacy of treatment of tension-type headache with either ketoprofen or ibuprofen and naproxen sodium were evaluated in a prospective, randomized, double-blind parallel-group-study in 345 subjects." | 9.08 | Comparison ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache. ( Lange, R; Lentz, R, 1995) |
"Ibuprofen 400 mg provides an important benefit in terms of being pain free at 2 hours for a small number of people with frequent episodic tension-type headache who have an acute headache with moderate or severe initial pain." | 8.91 | Ibuprofen for acute treatment of episodic tension-type headache in adults. ( Bendtsen, L; Derry, S; Moore, RA; Wiffen, PJ, 2015) |
"We documented localized periorbital edema in one patient with ibuprofen sensitivity without underlying chronic urticaria." | 7.73 | Localized periorbital edema induced by Ibuprofen. ( Ogawa, H; Palungwachira, P, 2005) |
"Ibuprofen was associated with a lower likelihood of the occurrence of any events and gastrointestinal adverse events compared with placebo and paracetamol (OR: 0." | 7.01 | Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis. ( Albunaian, N; Alfehaid, M; Alhamoud, M; Alhumrran, H; Alnasser, A; Ferwana, M, 2023) |
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 6.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache." | 5.12 | Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007) |
"Simple analgesics such as ibuprofen, aspirin, and acetaminophen have long been used in the treatment of tension-type headache." | 5.09 | The use of ibuprofen plus caffeine to treat tension-type headache. ( Diamond, S; Freitag, FG, 2001) |
"The safety and efficacy of treatment of tension-type headache with either ketoprofen or ibuprofen and naproxen sodium were evaluated in a prospective, randomized, double-blind parallel-group-study in 345 subjects." | 5.08 | Comparison ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache. ( Lange, R; Lentz, R, 1995) |
"Ibuprofen 400 mg provides an important benefit in terms of being pain free at 2 hours for a small number of people with frequent episodic tension-type headache who have an acute headache with moderate or severe initial pain." | 4.91 | Ibuprofen for acute treatment of episodic tension-type headache in adults. ( Bendtsen, L; Derry, S; Moore, RA; Wiffen, PJ, 2015) |
"Though all non-narcotic analgesics have equivalent efficacy against tension-type headache, ibuprofen's generally favorable side-effect profile makes it a reasonable first choice." | 4.83 | Is any one analgesic superior for episodic tension-type headache? ( Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP, 2006) |
" For the acute treatment of migraine attacks or tension-type headache, ibuprofen (10 mg per kg body weight) or acetaminophen (15 mg per kg body weight) are recommended with highest evidence, intranasal sumatriptan (10 to 20 mg) can be given as second choice." | 4.81 | [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. ( Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M, 2002) |
"We documented localized periorbital edema in one patient with ibuprofen sensitivity without underlying chronic urticaria." | 3.73 | Localized periorbital edema induced by Ibuprofen. ( Ogawa, H; Palungwachira, P, 2005) |
"Ibuprofen was associated with a lower likelihood of the occurrence of any events and gastrointestinal adverse events compared with placebo and paracetamol (OR: 0." | 3.01 | Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis. ( Albunaian, N; Alfehaid, M; Alhamoud, M; Alhumrran, H; Alnasser, A; Ferwana, M, 2023) |
" Additional studies are needed to assess the relationship between caffeine dosing and clinical benefits in patients with TTH and migraine." | 2.55 | Caffeine in the management of patients with headache. ( Diener, HC; Garas, SY; Lipton, RB; Patel, K; Robbins, MS, 2017) |
" The fixed dose combination of ibuprofen and paracetamol significantly increases the rate of absorption of paracetamol, which has potential therapeutic benefits in terms of a faster analgesias onset." | 1.62 | [Clinical and pharmacological approaches to the choice of a drug for a tension-type headache relief]. ( Khaytovich, ED; Perkov, AV; Shikh, EV, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 2 (10.53) | 18.2507 |
2000's | 9 (47.37) | 29.6817 |
2010's | 6 (31.58) | 24.3611 |
2020's | 2 (10.53) | 2.80 |
Authors | Studies |
---|---|
Shikh, EV | 1 |
Khaytovich, ED | 1 |
Perkov, AV | 1 |
Alnasser, A | 1 |
Alhumrran, H | 1 |
Alfehaid, M | 1 |
Alhamoud, M | 1 |
Albunaian, N | 1 |
Ferwana, M | 1 |
Lipton, RB | 1 |
Diener, HC | 1 |
Robbins, MS | 1 |
Garas, SY | 1 |
Patel, K | 1 |
Duma, SN | 1 |
Derry, S | 1 |
Wiffen, PJ | 1 |
Moore, RA | 1 |
Bendtsen, L | 2 |
Beran, RG | 1 |
Yancey, J | 1 |
Saas, P | 1 |
Manzano, S | 1 |
Doyon-Trottier, E | 1 |
Bailey, B | 1 |
Kubitzek, F | 1 |
Ziegler, G | 1 |
Gold, MS | 1 |
Liu, JM | 1 |
Ionescu, E | 1 |
Palungwachira, P | 2 |
Ogawa, H | 1 |
Verhagen, AP | 1 |
Damen, L | 1 |
Berger, MY | 1 |
Passchier, J | 1 |
Merlijn, V | 1 |
Koes, BW | 1 |
Haag, G | 1 |
Buchgreitz, L | 1 |
Ashina, S | 1 |
Jensen, R | 1 |
Lange, R | 1 |
Lentz, R | 1 |
Schachtel, BP | 1 |
Furey, SA | 1 |
Thoden, WR | 1 |
Diamond, S | 2 |
Balm, TK | 1 |
Freitag, FG | 2 |
Sparano, N | 1 |
Evers, S | 1 |
Pothmann, R | 1 |
Uberall, M | 1 |
Naumann, E | 1 |
Gerber, WD | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Acute Headache Treatment in Pregnancy: Improvement in Pain Scores With Occipital Nerve Block vs PO Acetaminophen With Caffeine A Randomized Controlled Trial[NCT03951649] | Phase 4 | 62 participants (Actual) | Interventional | 2020-02-10 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT03951649)
Timeframe: 7 days
Intervention | days (Median) |
---|---|
Occipital Nerve Block | 6 |
Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 28 days
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 9 |
Oral Acetaminophen/Caffeine Group | 4 |
(NCT03951649)
Timeframe: 7 days
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 7 |
Oral Acetaminophen/Caffeine Group | 2 |
Other: Pain at injection site (NCT03951649)
Timeframe: 7 days
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 0 |
Oral Acetaminophen/Caffeine Group | 2 |
(NCT03951649)
Timeframe: 7 hours
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 0 |
Oral Acetaminophen/Caffeine Group | 0 |
(NCT03951649)
Timeframe: 4 hours
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 9 |
Oral Acetaminophen/Caffeine Group | 14 |
(NCT03951649)
Timeframe: 5 hours
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 4 |
Oral Acetaminophen/Caffeine Group | 2 |
Emergency department for treatment of headache since treatment asked at 28 day follow up (NCT03951649)
Timeframe: 28 days
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 5 |
Oral Acetaminophen/Caffeine Group | 1 |
(NCT03951649)
Timeframe: 120 min
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 5 |
Oral Acetaminophen/Caffeine Group | 5 |
Based on guidelines from the International Headache Society the primary outcome is the portion of women who experience resolution of headache or improvement of headache to mild range (VRS ≤ 3) at 2 hours following treatment with Occipital nerve block as compared to acetaminophen/caffeine cocktail. (NCT03951649)
Timeframe: 60-300 min
Intervention | Participants (Count of Participants) |
---|---|
Occipital Nerve Block | 20 |
Oral Acetaminophen/Caffeine Group | 16 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 60 min
Intervention | score on a scale (Median) |
---|---|
Occipital Nerve Block | 6 |
Oral Acetaminophen/Caffeine Group | 3 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 180min
Intervention | score on a scale (Median) |
---|---|
Occipital Nerve Block | 6 |
Oral Acetaminophen/Caffeine Group | 4 |
"Visual/verbal Rating Score (VRS). VRS is used to assess pain in patients. With 0 representing no pain at all and 10 representing worst possible pain.~Total Minimum score=0 Total Maximum score=10~Higher values represent worse pain. If VRS=0, then the headache pain is considered resolved." (NCT03951649)
Timeframe: 2 hrs
Intervention | score on a scale (Median) |
---|---|
Occipital Nerve Block | 6.0 |
Oral Acetaminophen/Caffeine Group | 6.5 |
8 reviews available for ibuprofen and Headache, Tension
Article | Year |
---|---|
Paracetamol versus ibuprofen in treating episodic tension-type headache: a systematic review and network meta-analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Ibuprofen; Network Meta-Analysis; Tension-Type Head | 2023 |
Caffeine in the management of patients with headache.
Topics: Abdominal Pain; Acetaminophen; Adult; Analgesics; Aspirin; Caffeine; Central Nervous System Stimulan | 2017 |
Ibuprofen for acute treatment of episodic tension-type headache in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Dic | 2015 |
Ibuprofen for Treatment of Episodic Tension-Type Headaches.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Tension-Type Headache | 2016 |
Myth: Ibuprofen is superior to acetaminophen for the treatment of benign headaches in children and adults.
Topics: Acetaminophen; Adolescent; Adult; Altitude Sickness; Analgesics, Non-Narcotic; Child; Headache; Huma | 2010 |
Is any one analgesic superior for episodic tension-type headache?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dos | 2006 |
[Self-medication of migraine and headache].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; | 2006 |
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].
Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psyc | 2002 |
7 trials available for ibuprofen and Headache, Tension
Article | Year |
---|---|
[A role of treatment of autonomic syndrome in patients with tension-type headache].
Topics: Administration, Oral; Adult; Analgesics, Non-Narcotic; Autonomic Nervous System; Autonomic Nervous S | 2015 |
Low-dose diclofenac potassium in the treatment of episodic tension-type headache.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, Drug; Double | 2003 |
Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache.
Topics: Adrenergic alpha-Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose- | 2007 |
Comparison ketoprofen, ibuprofen and naproxen sodium in the treatment of tension-type headache.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Human | 1995 |
Nonprescription ibuprofen and acetaminophen in the treatment of tension-type headache.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Male | 1996 |
Ibuprofen plus caffeine in the treatment of tension-type headache.
Topics: Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimul | 2000 |
The use of ibuprofen plus caffeine to treat tension-type headache.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Doub | 2001 |
4 other studies available for ibuprofen and Headache, Tension
Article | Year |
---|---|
[Clinical and pharmacological approaches to the choice of a drug for a tension-type headache relief].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Drug Combinations; Humans; Ibuprofen; Tension-T | 2021 |
Ibuprofen for the treatment of TTH.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Humans; Ibuprofen; Tension-Type Headache; Treatment | 2016 |
Localized periorbital edema induced by Ibuprofen.
Topics: Adult; Dose-Response Relationship, Drug; Drug Administration Schedule; Edema; Female; Follow-Up Stud | 2005 |
Is the combination of ibuprofen and caffeine effective for the treatment of a tension-type headache?
Topics: Analgesics, Non-Narcotic; Caffeine; Central Nervous System Stimulants; Double-Blind Method; Drug The | 2001 |