ibuprofen has been researched along with Erythema in 19 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Erythema: Redness of the skin produced by congestion of the capillaries. This condition may result from a variety of disease processes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Topical administration of chemicals such as methyl nicotinate that induce erythema have been employed to measure the effectiveness of formulations containing anti-inflammatory agents." | 9.12 | Establishing a minimal erythema concentration of methyl nicotinate for optimum evaluation of anti-inflammatories. ( Jumbelic, LC; Liebel, FT; Southall, MD, 2006) |
| " Drug lymphocyte stimulation tests implicated ibuprofen, a main component of the OTC drugs, which has the potential to induce this pathology, and a diagnosis of drug-induced liver injury with multiform exudative erythema was made." | 7.81 | Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen. ( Abe, M; Aritomo, K; Hiasa, Y; Hirooka, M; Ikeda, Y; Koizumi, Y; Kumagi, T; Matsuura, B; Ochi, H; Tada, F; Tokumoto, Y; Watanabe, T, 2015) |
| "Ibuprofen may be a safe alternative to corticosteroids for select patients with vitiligo that are unable to photoadapt." | 5.30 | Effect of combination NSAID and NBUVB treatment in non-photoadapters-A pilot study. ( Griffith, J; Hamzavi, I; Mehta, C; Mehta, D; Mohammad, T; Nicholson, C, 2019) |
| "Topical administration of chemicals such as methyl nicotinate that induce erythema have been employed to measure the effectiveness of formulations containing anti-inflammatory agents." | 5.12 | Establishing a minimal erythema concentration of methyl nicotinate for optimum evaluation of anti-inflammatories. ( Jumbelic, LC; Liebel, FT; Southall, MD, 2006) |
| "There was a statistically significant difference between pain measured by VAS, skin temperature and pain detection threshold measured at pad sites with pre-applied ibuprofen 5% cream and those with pre-applied aqueous cream, after elective DC cardioversion." | 5.11 | The effect of topical non-steroidal anti-inflammatory cream on the incidence and severity of cutaneous burns following external DC cardioversion. ( Ambler, JJ; Deakin, CD; Zideman, DA, 2005) |
| "The mechanism of topically applied methyl nicotinate-induced local cutaneous erythema was studied in normal human subjects." | 5.05 | Prostaglandins and nicotinate-provoked increase in cutaneous blood flow. ( Flowers, OV; Fortner, G; Kilpatrick, SJ; Reinhardt, LA; Streeter, WC; Wilkin, JK, 1985) |
| " Drug lymphocyte stimulation tests implicated ibuprofen, a main component of the OTC drugs, which has the potential to induce this pathology, and a diagnosis of drug-induced liver injury with multiform exudative erythema was made." | 3.81 | Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen. ( Abe, M; Aritomo, K; Hiasa, Y; Hirooka, M; Ikeda, Y; Koizumi, Y; Kumagi, T; Matsuura, B; Ochi, H; Tada, F; Tokumoto, Y; Watanabe, T, 2015) |
| "Ibuprofen is a commonly used non-steroidal anti-inflammatory drug administered to treat injuries, joint pain, and recurrent muscular skeletal pain." | 2.87 | Cutaneous irritancy of an ibuprofen medicated plaster in healthy volunteers. ( Bhatt, A; Connolly, MP; Maganji, M, 2018) |
| "Mechanical and thermal hyperalgesia had been induced 24 h before by irradiating skin patches on the ventral side of the upper leg." | 2.69 | Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man. ( Bickel, A; Dorfs, S; Forster, C; Handwerker, OH; Schmelz, M; Uhl, W, 1998) |
| "Ibuprofen and placebo were compared in a randomized, double-blind, cross-over study of 19 psoriatic patients receiving UV-B phototherapy to evaluate the symptomatic relief of UV-B-induced inflammation." | 2.66 | Ibuprofen in the treatment of UV-B-induced inflammation. ( Dodson, TB; Stern, RS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (36.84) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 5 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maganji, M | 1 |
| Connolly, MP | 1 |
| Bhatt, A | 1 |
| Mehta, C | 1 |
| Mohammad, T | 1 |
| Mehta, D | 1 |
| Griffith, J | 1 |
| Nicholson, C | 1 |
| Hamzavi, I | 1 |
| Watanabe, T | 1 |
| Abe, M | 1 |
| Tada, F | 1 |
| Aritomo, K | 1 |
| Ochi, H | 1 |
| Koizumi, Y | 1 |
| Tokumoto, Y | 1 |
| Hirooka, M | 1 |
| Kumagi, T | 1 |
| Ikeda, Y | 1 |
| Matsuura, B | 1 |
| Hiasa, Y | 1 |
| Gatson, NT | 1 |
| Travers, JB | 2 |
| Al-Hassani, M | 1 |
| Warren, SJ | 1 |
| Hyatt, AM | 1 |
| Eismann, R | 1 |
| Gaul, C | 1 |
| Wohlrab, J | 1 |
| Marsch, WC | 1 |
| Fiedler, E | 1 |
| Ambler, JJ | 1 |
| Zideman, DA | 1 |
| Deakin, CD | 1 |
| Jackson, LA | 1 |
| Dunstan, M | 1 |
| Starkovich, P | 1 |
| Dunn, J | 1 |
| Yu, O | 1 |
| Nelson, JC | 1 |
| Rees, T | 1 |
| Zavitkovsky, A | 1 |
| Jumbelic, LC | 1 |
| Liebel, FT | 1 |
| Southall, MD | 1 |
| Boulton, P | 1 |
| Purdy, RA | 1 |
| Bosch, EP | 1 |
| Dodick, DW | 1 |
| Gruber, K | 1 |
| Engels, B | 1 |
| Berner, G | 1 |
| Wagener, HH | 1 |
| Edwards, EK | 1 |
| Horwitz, SN | 1 |
| Frost, P | 1 |
| Kumar, JR | 1 |
| Haberman, HF | 1 |
| Ranadive, NS | 1 |
| Bickel, A | 1 |
| Dorfs, S | 1 |
| Schmelz, M | 1 |
| Forster, C | 2 |
| Uhl, W | 1 |
| Handwerker, OH | 1 |
| Adams, SS | 1 |
| Bresloff, P | 1 |
| Mason, CG | 1 |
| Takase, K | 1 |
| Masumoto, S | 1 |
| Okumura, M | 1 |
| Magerl, W | 1 |
| Beck, A | 1 |
| Geisslinger, G | 1 |
| Gall, T | 1 |
| Brune, K | 1 |
| Handwerker, HO | 1 |
| Johansson, EA | 1 |
| Stern, RS | 1 |
| Dodson, TB | 1 |
| Wilkin, JK | 1 |
| Fortner, G | 1 |
| Reinhardt, LA | 1 |
| Flowers, OV | 1 |
| Kilpatrick, SJ | 1 |
| Streeter, WC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Do NSAIDS or Executing Exercise Decrease Local Erythema, Site Swelling & Pain After INoculation: the NEED LESS PAIN Study"[NCT02807623] | 300 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| Effect of Combination Non Steroidal Antiinflammatory Drugs and Narrowband UVB Treatment in Non-Photoadapters[NCT05256147] | 3 participants (Actual) | Interventional | 2015-08-31 | Terminated (stopped due to difficulty in recruiting study population) | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Swelling at vaccination site (NCT02807623)
Timeframe: baseline, 48-72 hours, and 21- 28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
Reddening of the skin at vaccination site reported as the total number of participants with erythema over the duration of the study. (NCT02807623)
Timeframe: baseline, 48- 72 hours, 21-28 days (3 points)
| Intervention | Participants (Count of Participants) |
|---|---|
| Baseline | 0 |
| 48-72 Hours After Vaccination | 0 |
| 21-28 Days After Vaccination | 0 |
A Lactate meter was used to test the exercise group for lactate readings. Two lactate tests was performed for the exercise group at Visit 1, both pre and post Influenza vaccination. The first lactate reading was taken after the blood draw.The second lactate reading was obtained from a fingerstick from the hand opposite to the vaccination arm, ideally within 3-8 minutes after the study subject completes pushups. (NCT02807623)
Timeframe: Immediately prior to Influenza vaccine and 3-8 minutes after Influenza vaccine was administered and after push-ups were completed.
| Intervention | mmol/L (Mean) | |
|---|---|---|
| Lactate before pushups | Lactate after pushups | |
| Compound Exercise of Push-ups | 1.51 | 7.69 |
Level of Pain will be measured by validated pain scale, using a scale of 0 ( best, no pain) to 10 (worst, as bad as imaginable, completely interferes). (NCT02807623)
Timeframe: baseline, 48-72 hours and at 21-28 days ( 3 points )
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Visit 1 | Visit 2 | Visit 3 | |
| Compound Exercise of Push-ups | .14 | .19 | .13 |
| Ibuprofen | .39 | .56 | .28 |
| Placebo | .19 | .22 | .06 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 214.80 | 345.09 |
| Ibuprofen | 171.00 | 239.25 |
| Placebo | 216.75 | 343.03 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 149.22 | 232.58 |
| Ibuprofen | 177.78 | 243.13 |
| Placebo | 221.09 | 296.66 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 26.00 | 41.02 |
| Ibuprofen | 17.41 | 25.47 |
| Placebo | 26.09 | 34.09 |
Baseline lab specimen (visit 1, day 0, before immunization) and repeated between 21-28 days (visit 3) after immunization to measure serologic response (NCT02807623)
Timeframe: Day 0 and between 21-28 days (2 points)
| Intervention | Titer (Mean) | |
|---|---|---|
| Baseline (day 0, visit 1) | Followup (between 21-28 days, visit 3) | |
| Compound Exercise of Push-ups | 32.89 | 49.07 |
| Ibuprofen | 40.16 | 47.34 |
| Placebo | 36.69 | 44.78 |
1 review available for ibuprofen and Erythema
| Article | Year |
|---|---|
Red ear syndrome: case report and review of the literature.
Topics: Adult; Analgesics, Non-Narcotic; Ear Diseases; Edema; Erythema; Female; Humans; Hyperhidrosis; Ibupr | 2011 |
10 trials available for ibuprofen and Erythema
| Article | Year |
|---|---|
Cutaneous irritancy of an ibuprofen medicated plaster in healthy volunteers.
Topics: Administration, Cutaneous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Calcium Sulfate; Double-B | 2018 |
Effect of combination NSAID and NBUVB treatment in non-photoadapters-A pilot study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Erythema; Female; Humans; Ibuprofen; Middle Aged; Pil | 2019 |
The effect of topical non-steroidal anti-inflammatory cream on the incidence and severity of cutaneous burns following external DC cardioversion.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Burns, Electric; Double-Bli | 2005 |
Prophylaxis with acetaminophen or ibuprofen for prevention of local reactions to the fifth diphtheria-tetanus toxoids-acellular pertussis vaccination: a randomized, controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Pres | 2006 |
Establishing a minimal erythema concentration of methyl nicotinate for optimum evaluation of anti-inflammatories.
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Contact; Erythe | 2006 |
Effects of antihyperalgesic drugs on experimentally induced hyperalgesia in man.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Diuresis; Double-Bli | 1998 |
Differential effects of dipyrone, ibuprofen, and paracetamol on experimentally induced pain in man.
Topics: Acetaminophen; Adult; Analgesia; Dipyrone; Erythema; Female; Humans; Ibuprofen; Male; Muscle, Smooth | 1992 |
Proquazone: a treatment for lymphocytic infiltration of the skin. Comparative study with 2 other nonsteroid anti-inflammatory drugs.
Topics: Adult; Aged; Clinical Trials as Topic; Erythema; Female; Humans; Ibuprofen; Indomethacin; Lymphocyte | 1987 |
Ibuprofen in the treatment of UV-B-induced inflammation.
Topics: Adult; Clinical Trials as Topic; Dermatitis; Double-Blind Method; Erythema; Humans; Ibuprofen; Psori | 1985 |
Prostaglandins and nicotinate-provoked increase in cutaneous blood flow.
Topics: Administration, Oral; Administration, Topical; Adult; Aspirin; Double-Blind Method; Doxepin; Drug In | 1985 |
8 other studies available for ibuprofen and Erythema
| Article | Year |
|---|---|
Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen.
Topics: Adult; Asian People; Chemical and Drug Induced Liver Injury; Drug Eruptions; Erythema; Female; Fever | 2015 |
Progression of toxic epidermal necrolysis after tanning bed exposure.
Topics: Cell Line; Disease Progression; Erythema; Female; Humans; Ibuprofen; Immunoglobulins, Intravenous; K | 2011 |
Primary and secondary red ear syndrome: implications for treatment.
Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear | 2007 |
[Pharmacologic-toxicologic study of an ibuprofen-containing creme].
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Erythema; Female; Gr | 1983 |
Reduction of the erythema response to ultraviolet light by nonsteroidal antiinflammatory agents.
Topics: Anti-Inflammatory Agents; Aspirin; Erythema; Humans; Ibuprofen; Indomethacin; Ultraviolet Rays | 1982 |
Modulation of 8-methoxypsoralen-photoinduced cutaneous inflammatory reactions by various chemotherapeutic agents in vivo.
Topics: Acetophenones; Animals; Capillary Permeability; Erythema; Ibuprofen; Indoles; Indomethacin; Masoproc | 1996 |
Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (-)-isomer.
Topics: Acetylcholine; Animals; Cattle; Cyclooxygenase Inhibitors; Erythema; Guinea Pigs; Ibuprofen; In Vitr | 1976 |
[Anti-inflammatory action of 2-(2-fluoro-4-biphenylyl) propionic acid (flubiprofen].
Topics: Animals; Arthritis, Rheumatoid; Capillary Permeability; Edema; Erythema; Flurbiprofen; Granuloma; Gu | 1975 |