ibuprofen has been researched along with Endotoxemia in 12 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The primary purpose of this study was to measure the influence of ibuprofen use during the 160-km Western States Endurance Run on endotoxemia, inflammation, and plasma cytokines." | 9.12 | Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition. ( Davis, JM; Dumke, CL; Henson, DA; Lind, RH; McAnulty, LS; McAnulty, SR; Morrow, JD; Murphy, EA; Nieman, DC; Oley, K; Utter, AC, 2006) |
| "To measure the effect of experimental endotoxemia and anti-inflammatory therapy on plasma dehydroepiandrosterone (DHEA) levels in humans." | 9.09 | Plasma dehydroepiandrosterone levels during experimental endotoxemia and anti-inflammatory therapy in humans. ( Bornstein, SR; Chrousos, GP; Preas, HL; Suffredini, AF; Tauchnitz, R; Wolkersdörfer, GW, 2000) |
| "Ibuprofen, a cyclooxygenase inhibitor, improves pulmonary and cardiovascular injury in endotoxemia." | 7.70 | Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. ( Heidemann, SM; Ofenstein, JP; Sarnaik, AP, 1999) |
| "Sepsis is still a major cause of death and many efforts have been made to improve the physical condition of sepsis patients and to reduce the high mortality rate associated with this disease." | 5.42 | Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis. ( Barcena Varela, S; Brandenburg, K; Drömann, D; Ferrer-Espada, R; Goldmann, T; Gutsmann, T; Heinbockel, L; Martinez de Tejada, G; Marwitz, S; Mier, W; Reiling, N; Schürholz, T, 2015) |
| "The primary purpose of this study was to measure the influence of ibuprofen use during the 160-km Western States Endurance Run on endotoxemia, inflammation, and plasma cytokines." | 5.12 | Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition. ( Davis, JM; Dumke, CL; Henson, DA; Lind, RH; McAnulty, LS; McAnulty, SR; Morrow, JD; Murphy, EA; Nieman, DC; Oley, K; Utter, AC, 2006) |
| "To measure the effect of experimental endotoxemia and anti-inflammatory therapy on plasma dehydroepiandrosterone (DHEA) levels in humans." | 5.09 | Plasma dehydroepiandrosterone levels during experimental endotoxemia and anti-inflammatory therapy in humans. ( Bornstein, SR; Chrousos, GP; Preas, HL; Suffredini, AF; Tauchnitz, R; Wolkersdörfer, GW, 2000) |
| "To evaluate the effects of endotoxemia on respiratory controller function, 12 subjects were randomized to receive endotoxin or saline; six also received ibuprofen, a cyclooxygenase inhibitor, and six received placebo." | 5.09 | Effect of endotoxin on ventilation and breath variability: role of cyclooxygenase pathway. ( Banks, SM; Godin, PJ; Jubran, A; Preas, HL; Reda, D; Suffredini, AF; Tobin, MJ; Vandivier, RW, 2001) |
| "The objective of our study was to determine the role of ibuprofen in protecting neutropenic rats from cardiopulmonary injury due to endotoxemia." | 3.71 | Ibuprofen attenuates early lung injury in endotoxemic, neutropenic rats. ( Daphtary, KM; Glibetic, M; Heidemann, SM, 2001) |
| " To assess the role of MIP-1alpha and MIP-1beta in human inflammation, healthy subjects were studied during experimental endotoxemia with prior administration of ibuprofen, a cyclooxygenase inhibitor, or dimeric p75 tumor necrosis factor (TNF)-alpha receptor, a TNF antagonist; septic patients were also studied." | 3.70 | Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis. ( Banks, SM; O'Grady, NP; Preas, HL; Reda, D; Suffredini, AF; Tropea, M; Vandivier, RW, 1999) |
| "Ibuprofen, a cyclooxygenase inhibitor, improves pulmonary and cardiovascular injury in endotoxemia." | 3.70 | Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia. ( Heidemann, SM; Ofenstein, JP; Sarnaik, AP, 1999) |
| "Sepsis is still a major cause of death and many efforts have been made to improve the physical condition of sepsis patients and to reduce the high mortality rate associated with this disease." | 1.42 | Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis. ( Barcena Varela, S; Brandenburg, K; Drömann, D; Ferrer-Espada, R; Goldmann, T; Gutsmann, T; Heinbockel, L; Martinez de Tejada, G; Marwitz, S; Mier, W; Reiling, N; Schürholz, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, HH | 1 |
| Shin, JS | 1 |
| Lee, WS | 1 |
| Ryu, B | 1 |
| Jang, DS | 1 |
| Lee, KT | 1 |
| Heinbockel, L | 1 |
| Marwitz, S | 1 |
| Barcena Varela, S | 1 |
| Ferrer-Espada, R | 1 |
| Reiling, N | 1 |
| Goldmann, T | 1 |
| Gutsmann, T | 1 |
| Mier, W | 1 |
| Schürholz, T | 1 |
| Drömann, D | 1 |
| Brandenburg, K | 1 |
| Martinez de Tejada, G | 1 |
| Nieman, DC | 1 |
| Henson, DA | 1 |
| Dumke, CL | 1 |
| Oley, K | 1 |
| McAnulty, SR | 1 |
| Davis, JM | 1 |
| Murphy, EA | 1 |
| Utter, AC | 1 |
| Lind, RH | 1 |
| McAnulty, LS | 1 |
| Morrow, JD | 1 |
| Santos, AA | 1 |
| Wilmore, DW | 1 |
| Mansilla-Roselló, A | 1 |
| Ferrón-Orihuela, JA | 1 |
| Ruiz-Cabello, F | 1 |
| Garrote-Lara, D | 1 |
| Delgado-Carrasco, S | 1 |
| Tamayo-Pozo, F | 1 |
| Bornstein, SR | 2 |
| Preas, HL | 5 |
| Chrousos, GP | 2 |
| Suffredini, AF | 5 |
| O'Grady, NP | 1 |
| Tropea, M | 1 |
| Reda, D | 2 |
| Vandivier, RW | 2 |
| Banks, SM | 2 |
| Heidemann, SM | 2 |
| Ofenstein, JP | 1 |
| Sarnaik, AP | 1 |
| Wolkersdörfer, GW | 1 |
| Tauchnitz, R | 1 |
| Nylen, ES | 1 |
| Snider, RH | 1 |
| Becker, KL | 1 |
| White, JC | 1 |
| Agosti, JM | 1 |
| Jubran, A | 1 |
| Godin, PJ | 1 |
| Tobin, MJ | 1 |
| Daphtary, KM | 1 |
| Glibetic, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Milk Fat Globule Membrane (MFGM) on Gut Barrier Protection in Runners[NCT03176212] | 14 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for ibuprofen and Endotoxemia
| Article | Year |
|---|---|
Ibuprofen use, endotoxemia, inflammation, and plasma cytokines during ultramarathon competition.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Colony-Stimulating Factors; Cr | 2006 |
The systemic inflammatory response: perspective of human endotoxemia.
Topics: Body Temperature; Cytokines; Endotoxemia; Endotoxins; Escherichia coli Infections; Heart Rate; Human | 1996 |
Circulating leptin levels during acute experimental endotoxemia and antiinflammatory therapy in humans.
Topics: Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents, Non-Steroidal; Endotoxemia; Endotoxins | 1998 |
Plasma dehydroepiandrosterone levels during experimental endotoxemia and anti-inflammatory therapy in humans.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dehydroepiandrosterone; E | 2000 |
Effect of endotoxin on ventilation and breath variability: role of cyclooxygenase pathway.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Gas Analysis; Carbon Dioxide; Dyspnea; Endotox | 2001 |
7 other studies available for ibuprofen and Endotoxemia
| Article | Year |
|---|---|
Biflorin, Isolated from the Flower Buds of Syzygium aromaticum L., Suppresses LPS-Induced Inflammatory Mediators via STAT1 Inactivation in Macrophages and Protects Mice from Endotoxin Shock.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Dinoprostone; Disease Models, Anim | 2016 |
Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis.
Topics: Amino Acid Sequence; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dinopr | 2015 |
Interleukin-1beta and ibuprofen effects on CD4/CD8 cells after endotoxic challenge.
Topics: Animals; CD4-CD8 Ratio; Dinoprostone; Endotoxemia; Female; Ibuprofen; Interleukin-1; Lymphocyte Subs | 1996 |
Detection of macrophage inflammatory protein (MIP)-1alpha and MIP-1beta during experimental endotoxemia and human sepsis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Chemokine CCL3; Chemokine CCL4; Child; Cyc | 1999 |
Ibuprofen attenuates cardiopulmonary dysfunction by modifying vascular tone in endotoxemia.
Topics: Animals; Blood Pressure; Cardiovascular System; Cyclooxygenase Inhibitors; Endotoxemia; Ibuprofen; L | 1999 |
Effects of anti-inflammatory agents on serum levels of calcitonin precursors during human experimental endotoxemia.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; C-Reactive Protein; Calciton | 2001 |
Ibuprofen attenuates early lung injury in endotoxemic, neutropenic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Che | 2001 |