ibuprofen and Emesis, Postoperative
ibuprofen has been researched along with Emesis, Postoperative in 9 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with ibuprofen before major hip surgery does not improve the pain scores or reduce morphine requirement but significantly increases blood loss." | 9.10 | Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgery. ( Bugter, ML; Dirksen, R; Jhamandas, K; Milne, B; Slappendel, R; Weber, EW, 2003) |
| "Pain is often cited as one of the worst features of medical abortion." | 6.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "Pretreatment with ibuprofen before major hip surgery does not improve the pain scores or reduce morphine requirement but significantly increases blood loss." | 5.10 | Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgery. ( Bugter, ML; Dirksen, R; Jhamandas, K; Milne, B; Slappendel, R; Weber, EW, 2003) |
| "Preemptive analgesia may improve postoperative pain management, but the optimal regimen is unclear." | 2.82 | Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis. ( Chin, V; Houle, TT; Li, C; Ma, H; Mueller, A; Wang, D; Wang, J; Xuan, C; Yan, W, 2022) |
| "Pain is often cited as one of the worst features of medical abortion." | 2.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "All patients were assessed for postoperative nausea and vomiting by a blinded research nurse." | 2.80 | A Randomized Controlled Trial of Oral Versus Intravenous Administration of a Nonnarcotic Analgesia Protocol Following Pediatric Craniosynostosis Corrections on Nausea and Vomiting Rates. ( Dimas, V; Ditthakasem, K; Fearon, JA; Herbert, MA, 2015) |
| "Dexamethasone is widely used to prevent postoperative nausea and vomiting (PONV) in pediatric tonsillectomy." | 2.73 | Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial. ( Czarnetzki, C; Desmeules, J; Dulguerov, P; Dumont, L; Elia, N; Giger, R; Landis, BN; Lysakowski, C; Tramèr, MR, 2008) |
| " Dose-response relationships show that higher doses of ibuprofen may be particularly effective." | 2.40 | Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. ( McQuay, HJ; Moore, RA, 1998) |
Research
Studies (9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Xuan, C | 3 |
| Yan, W | 3 |
| Wang, D | 3 |
| Li, C | 3 |
| Ma, H | 3 |
| Mueller, A | 3 |
| Chin, V | 3 |
| Houle, TT | 3 |
| Wang, J | 3 |
| Jotić, A | 1 |
| Savić Vujović, K | 1 |
| Milovanović, J | 1 |
| Vujović, A | 1 |
| Radin, Z | 1 |
| Milić, N | 1 |
| Vučković, S | 1 |
| Medić, B | 1 |
| Prostran, M | 1 |
| Fearon, JA | 1 |
| Dimas, V | 1 |
| Ditthakasem, K | 1 |
| Herbert, MA | 1 |
| Dragoman, MV | 1 |
| Grossman, D | 1 |
| Kapp, N | 1 |
| Huong, NM | 1 |
| Habib, N | 1 |
| Dung, DL | 1 |
| Tamang, A | 1 |
| Czarnetzki, C | 1 |
| Elia, N | 1 |
| Lysakowski, C | 1 |
| Dumont, L | 1 |
| Landis, BN | 1 |
| Giger, R | 1 |
| Dulguerov, P | 1 |
| Desmeules, J | 1 |
| Tramèr, MR | 1 |
| Jaeger, P | 1 |
| Grevstad, U | 1 |
| Henningsen, MH | 1 |
| Gottschau, B | 1 |
| Mathiesen, O | 1 |
| Dahl, JB | 1 |
| Bugter, ML | 1 |
| Dirksen, R | 1 |
| Jhamandas, K | 1 |
| Slappendel, R | 1 |
| Weber, EW | 1 |
| Milne, B | 1 |
| Marcus, RL | 1 |
| Wong, CA | 1 |
| Lehor, A | 1 |
| McCarthy, RJ | 1 |
| Yaghmour, E | 1 |
| Yilmaz, M | 1 |
| McQuay, HJ | 1 |
| Moore, RA | 1 |
Clinical Trials (11)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Antiemetic and Analgesic Efficacy and Safety of Dexamethasone for Paediatric Adeno-tonsillectomy - A Randomised, Placebo-controlled, Double-blind, Dose-finding Study[NCT00403806] | Phase 4 | 215 participants (Actual) | Interventional | 2005-02-28 | Terminated (stopped due to drug-related harm) | ||
| Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy - a Randomized, Double-blind, Placebo-controlled Trial[NCT03783182] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-09-10 | Recruiting | ||
| Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty[NCT03915522] | 140 participants (Anticipated) | Interventional | 2018-05-14 | Recruiting | |||
| Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856] | Phase 4 | 0 participants (Actual) | Interventional | 2015-11-30 | Withdrawn (stopped due to Lack of funding) | ||
| Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty[NCT01759277] | Phase 4 | 80 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Prospective, Double-blind, Randomized Study to Evaluate a Single Shot Adductor Canal Nerve Block Versus Femoral Nerve Block Combined With LIA (Local Infiltration Analgesia): Early Postoperative Period Functional Outcomes After Total Knee Replacement[NCT02218814] | 106 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques?[NCT02788019] | Phase 4 | 52 participants (Actual) | Interventional | 2016-05-26 | Terminated (stopped due to Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage.) | ||
| The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty[NCT01261897] | Phase 4 | 40 participants (Anticipated) | Interventional | 2011-01-31 | Completed | ||
| Optimal Volume of Bupivacaine in Adductor Canal Nerve Block in Patients Undergoing Unilateral Cruciate Ligament Reconstruction Surgery[NCT02557386] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Ultrasound Guided Single Shot Adductor Canal Block (ACB) Versus Single Shot Femoral Nerve Block (FNB) for Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction in Pediatrics[NCT03053401] | 52 participants (Actual) | Interventional | 2017-02-09 | Completed | |||
| Continuous Adductor Canal Block With Epidural Analgesia for Total Knee Arthroplasty: A Prospective, Randomized, Double-blinded, Placebo-Controlled Trial[NCT02121392] | 165 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trial Outcomes
Hours Until Discharge Readiness
Discharge readiness is the number of hours until meeting the following 4 criteria: (1) adequate analgesia (defined as pain less than 4 on a NRS of 0-10); (2) independence from intravenous analgesics; (3) ability to ambulate 30 m and (4) ability to stand, walk 3 m, and return to a sitting position without another's assistance. (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | hours (Median) |
|---|---|
| Control | 61 |
| Experimental | 55 |
Time to Adequate Analgesia
The time in hours until adequate analgesia is defined as pain less than 4 on a Numeric Rating Scale of 0-10, with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 61.6 |
| Experimental | 61.0 |
Time Until Ambulation at Least 30 Meters
The time in hours until a patient could ambulate at least 30 meters independently (regardless of time to achieve the 30 meters) (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 40.9 |
| Experimental | 56.6 |
Time Until Independence From Intravenous Analgesics of at Least 12 Hours
The time in hours until no intravenous analgesics were required for at least 12 hours (without future intravenous use during admission) (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 46.1 |
| Experimental | 47.5 |
Time Until Timed Up and Go Test Achieved
The timed-up-and-go (TUG) test measures the ability and speed of standing from a sitting position, walking 3 meters and returning to the original seated position independent from the assistance of healthcare personnel. This variable measured the time in hours until the patient could successfully achieve this test independently, regardless of the amount of time required. (NCT01759277)
Timeframe: Hours
| Intervention | Hours (Mean) |
|---|---|
| Control | 33.4 |
| Experimental | 46.8 |
Opioid Consumption
Amount of opioid consumed as measured with intravenous morphine equivalents in milligrams (NCT01759277)
Timeframe: Postoperative Days 0-3
| Intervention | milligrams (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Recovery Room | Postoperative Day 0 (day) | Postoperative Day 0 (evening) | Postoperative Day 1 (night) | Postoperative Day 1 (Day) | Postoperative Day 1 (evening) | Postoperative Day 2 (night) | Postoperative Day 2 (day) | Postoperative Day 2 (evening) | Postoperative Day 3 (night | |
| Control | 8.6 | 0.9 | 7.2 | 5.1 | 11.0 | 8.6 | 4.1 | 9.6 | 6.5 | 4.9 |
| Experimental | 8.0 | 1.5 | 8.5 | 5.6 | 12.6 | 10.9 | 5.6 | 10.2 | 7.2 | 5.1 |
Pain Level
The amount of pain evaluated using the 0-10 Numeric Rating Scale with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: Postoperative Days 1-3
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Postoperative Day 1 (08:00-16:00) | Postoperative Day 2 (08:00-16:00) | Postoperative Day 3 (00:00-8:00) | |
| Control | 4.4 | 3.7 | 2.5 |
| Experimental | 3.7 | 3.4 | 2.8 |
Number of Grid Points With Change of Sensation to Pinprick After Blockade
The distribution of cutaneous sensation affected by the different techniques of adductor canal blockade is assessed using a monofilament Neuropen to prick points on a 20 point grid applied to the skin in a standard fashion according to this method: A grid will be marked starting with anatomical landmarks at the knee joint: the medial inter-knee-joint point where the tibia meets the femur, the mid medial patella, the mid lateral patella, and along the same line at the semitendinosus tendon and 5cm posterior from that point. Then 5cm intervals will be plotted progressing cephalad to a total of 15 centimeters. This will yield 20 grid points (5x4 points). Once the grid is made, testing proceeds with a Neuropen on a scale of 0-1, with 1 = normal sharp sensation, 0 = change of sensation. The Neuropen is used for the standardization of force. (NCT02788019)
Timeframe: 20 minutes
| Intervention | points of cutaneous sensation (Mean) |
|---|---|
| Mid-Thigh Adductor Block | 19.81 |
| Distal-Thigh Adductor Block | 20 |
Quadriceps Muscle Strength in Kilogram-force (Kgf)
Measuring the quadriceps muscle strength (surgical side) using a dynamometer.Patients were placed supine with a cushion underneath their knee, resulting in a 45-degree angle at the knee. A dynamometer was placed on the anterior of the ankle, between the malleoli. Patients were instructed to extend their legs three times each, with a 30-s pause between each attempt (Lafayette Manual Muscle Test System; Lafayette Instrument Company, Lafayette, IN; and all three dynamometer readings in Kgf unit for each leg were recorded.Kgf is a gravitational metric unit force ,it is equal to the magnitude of the force exerted on one kilogram of mass under standard gravity. (NCT03053401)
Timeframe: 4 hours following peripheral nerve block performance
| Intervention | Kilogram-force (Kgf) (Median) |
|---|---|
| Adductor Canal Block | 1.1 |
| Femoral Nerve Block | 0.0 |
Total Opioid Consumption at 24 Hours Post-block
Total intravenous morphine/morphine equivalent consumption in milligrams (mg) at 24 hours post-block (NCT03053401)
Timeframe: 24 hours following peripheral nerve block performance.
| Intervention | milligrams (Mean) |
|---|---|
| Adductor Canal Block | 28.9 |
| Femoral Nerve Block | 26.9 |
Post-operative Pain Scores Using the Numeric Pain Scoring System (NS)
Assessed by Numeric Scale (NS) pain scoring system. Minimum 0 and maximum 10 . Higher scores means worse outcome (pain) (NCT03053401)
Timeframe: 4 hours and 24 hours
| Intervention | score on a scale (Median) | |
|---|---|---|
| 4 hours post block | 24 hours post block | |
| Adductor Canal Block | 4.5 | 5.0 |
| Femoral Nerve Block | 4.5 | 6.0 |
Number of Hospital Days Until Discharge Criteria Are Met
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Days (Mean) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 2.42 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 2.67 |
Number of Participants With Adverse Events Related to Adductor Canal Nerve Block Catheter
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
Number of Participants With Bleeding Complications at Adductor Canal Nerve Block Catheter Site
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
Morphine Equivalents
(NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | milligrams of morphine (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 12.5 | 73.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 11.9 | 96.5 |
Physical Therapy Ambulation Distance
(NCT02121392)
Timeframe: Daily on postoperative days one and two
| Intervention | meters (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 17.6 | 39.4 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 13.8 | 32.5 |
Range of Motion
Knee range of motion (ROM) was measured (in degrees) during physical therapy. (NCT02121392)
Timeframe: postoperative day 1 and 2
| Intervention | degrees (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 40.6 | 62.5 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 51.4 | 71.3 |
Range of Motion at 3 and 6 Week Follow up
(NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | degrees (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 94.3 | 105 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 98.2 | 109 |
Visual Analog Score for Pain
"The visual analog scale (VAS) is a pain rating scale. Scores are based on self-reported measures of symptoms that are recorded with a single mark placed at one point along the length of a line that represents a continuum between the two ends of the scale-no pain on the left end of the scale (equal to a score of 0) and the worst pain on the right end of the scale (equal to a score of 100)." (NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | mm (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 26.9 | 28.6 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 27.9 | 36.4 |
Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC)
The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self administered questionnaire consisting of 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The subscale scores can vary, with pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. A sum of the scores for all three subscales yields a total WOMAC score. (NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | score on a scale (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 29.1 | 27.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 37.8 | 32.9 |
Reviews
2 reviews available for ibuprofen and Emesis, Postoperative
| Article | Year |
|---|---|
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Efficacy of preemptive analgesia treatments for the management of postoperative pain: a network meta-analysis.
Topics: Analgesia, Epidural; Analgesics, Opioid; Gabapentin; Humans; Ibuprofen; Network Meta-Analysis; Pain, | 2022 |
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 1998 |
Trials
7 trials available for ibuprofen and Emesis, Postoperative
| Article | Year |
|---|---|
Pain Management After Surgical Tonsillectomy: Is There a Favorable Analgesic?
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Female; Humans; I | 2019 |
A Randomized Controlled Trial of Oral Versus Intravenous Administration of a Nonnarcotic Analgesia Protocol Following Pediatric Craniosynostosis Corrections on Nausea and Vomiting Rates.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anesthesia Recovery Perio | 2015 |
Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; | 2016 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Dexamethasone and risk of nausea and vomiting and postoperative bleeding after tonsillectomy in children: a randomized trial.
Topics: Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child; C | 2008 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Prior ibuprofen exposure does not augment opioid drug potency or modify opioid requirements for pain inhibition in total hip surgery.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Blood L | 2003 |
Postoperative epidural morphine for postpartum tubal ligation analgesia.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesic | 2005 |