Page last updated: 2024-10-28

ibuprofen and Drug Overdose

ibuprofen has been researched along with Drug Overdose in 74 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.

Research Excerpts

ExcerptRelevanceReference
"A 28-year-old man with schizophrenia intentionally ingested a lethal dose of acetaminophen and an unknown quantity of ibuprofen."7.74Rhabdomyolysis and necrotic bowel after acetaminophen and ibuprofen overdose. ( Dunn, T; Katz, D; Nelson, H; Singh, G; Thomsen, D; Voigt, M; Whitaker, E, 2007)
"We present a case of a young man with acute pancreatitis probably secondary to an ibuprofen overdose."7.73A case of probable ibuprofen-induced acute pancreatitis. ( Conlon, KC; Magill, P; Neary, P; Ridgway, PF, 2006)
"To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose."7.69Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995)
"A 21-month-old boy developed acute renal failure with severe metabolic acidosis after ingestion of ibuprofen 8 g."7.69Hypocalcemia and hypomagnesemia after ibuprofen overdose. ( al-Harbi, NN; Domrongkitchaiporn, S; Lirenman, DS, 1997)
" The aim of this review is to determine if there are any clinically relevant differences in safety between ibuprofen and paracetamol that may recommend one agent over the other in the management of fever and discomfort in children older than 3 months of age."4.95A clinical and safety review of paracetamol and ibuprofen in children. ( Kanabar, DJ, 2017)
" Hemodialysis appears to be a beneficial therapeutic option in cases of massive acetaminophen ingestion with coma and lactic acidosis."3.83Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics. ( Ghannoum, M; Gosselin, S; Grunbaum, AM; Kazim, S; Villeneuve, E, 2016)
"A 28-year-old man with schizophrenia intentionally ingested a lethal dose of acetaminophen and an unknown quantity of ibuprofen."3.74Rhabdomyolysis and necrotic bowel after acetaminophen and ibuprofen overdose. ( Dunn, T; Katz, D; Nelson, H; Singh, G; Thomsen, D; Voigt, M; Whitaker, E, 2007)
"We present a case of a young man with acute pancreatitis probably secondary to an ibuprofen overdose."3.73A case of probable ibuprofen-induced acute pancreatitis. ( Conlon, KC; Magill, P; Neary, P; Ridgway, PF, 2006)
"The results of this survey concerning antipyretic treatment of children by their Jewish and Bedouin Moslem caregivers suggest that lighter body weight and the use of acetaminophen rectal suppositories were associated with the administration of higher-than-recommended doses of acetaminophen."3.73Determinants of antipyretic misuse in children up to 5 years of age: a cross-sectional study. ( Bilenko, N; Gorodischer, R; Okbe, R; Press, J; Tessler, H, 2006)
"To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose."3.69Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995)
"A 21-month-old boy developed acute renal failure with severe metabolic acidosis after ingestion of ibuprofen 8 g."3.69Hypocalcemia and hypomagnesemia after ibuprofen overdose. ( al-Harbi, NN; Domrongkitchaiporn, S; Lirenman, DS, 1997)
"A 14-year-old girl with systemic lupus erythematosus presented with a mixed overdose of paracetamol, ibuprofen and azathioprine (1500 mg) following a deliberate self-harm attempt."2.49Intentional overdose of azathioprine in a patient with systemic lupus erythematosus. ( Khan, AM; Mahmood, K; Martin, K; Ramanan, AV, 2013)
"The biochemical findings suggest renal tubular acidosis, type 2, most likely caused by the excess intake of ibuprofen, a drug which can cause renal dysfunctions with life-threatening electrolyte abnormalities."2.40[Renal tubular acidosis with severe hypokalemic tetraparesis after ibuprofen intake]. ( Druschky, A; Erbguth, F; Gaul, C; Heckmann, JG; Neundörfer, B; Schöcklmann, H, 1999)
" The benefit-risk profile of mefenamic acid should now be re-evaluated in light of effective and less toxic alternatives."1.46Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service. ( Cooper, G; Crichton, S; Eddleston, M; Kamour, A; Lupton, DJ; Thomas, SH; Thompson, JP; Vale, JA, 2017)
"Ibuprofen is a commonly used non-steroidal anti-inflammatory drug."1.34A report of two deaths from massive ibuprofen ingestion. ( Holubek, W; Lopez, O; Nelson, L; Nurok, S; Stolbach, A; Wetter, A, 2007)
"Ibuprofen is a nonsteroidal anti-inflammatory drug available over the counter and on prescription for the management of pain and inflammation."1.33Fatality after deliberate ingestion of sustained-release ibuprofen: a case report. ( Dargan, PI; Jones, AL; Monaghan, J; Streete, P; Wood, DM, 2006)
"The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care."1.31Massive ibuprofen ingestion with survival. ( Bronstein, AC; McGuire, T; Seifert, SA, 2000)
" We explore the toxicities of OTC cough and cold medications, discuss mechanisms of dosing errors, and suggest why physicians should be more vigilant in specifically inquiring about OTCs when evaluating an ill child."1.31Toxicity of over-the-counter cough and cold medications. ( Gunn, VL; Liebelt, EL; Serwint, JR; Taha, SH, 2001)
" Although the risk of developing toxic reactions to acetaminophen appears to be lower in children than in adults, such reactions occur in pediatric patients from intentional overdoses."1.31Acetaminophen toxicity in children. ( , 2001)
"Acute renal insufficiency is a rare, reversible effect of ibuprofen overdose documented in adults, but we could find no published pediatric cases."1.29Acute renal insufficiency in ibuprofen overdose. ( Gazarian, M; Johnson, D; Kim, J; Verjee, Z, 1995)
"Ibuprofen was identified and quantitated in the following tissues: heart blood (518."1.29Tissue distribution of ibuprofen in a fatal overdose. ( Kunsman, GW; Rohrig, TP, 1993)

Research

Studies (74)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.35)18.7374
1990's22 (29.73)18.2507
2000's24 (32.43)29.6817
2010's22 (29.73)24.3611
2020's5 (6.76)2.80

Authors

AuthorsStudies
Pollack, BE2
Barbaro, RP2
Selewski, DT2
Carlton, EF2
Isbister, GK2
Polanski, R1
Cooper, JM1
Keegan, M1
Isoardi, KZ1
Murshed, M1
Pham, A1
Vithani, K1
Salim, M1
Boyd, BJ1
Butty, EM1
Suter, SE1
Chalifoux, NV1
Lynch, AM1
Mauro, KD1
Moyle, RB1
Ehrhardt, CM1
Robertson, JB1
Culler, CA1
Londoño, LA1
Vigani, A1
Ueda, Y1
Labato, MA1
Walton, S1
Ryan, KA1
Davis, JL1
Acierno, M1
Geith, S1
Renner, B1
Rabe, C1
Stenzel, J1
Eyer, F1
Paul, IM1
Reynolds, KM1
Delva-Clark, H1
Burnham, RI1
Green, JL1
Pilgrim, JL2
Dobbin, M1
Drummer, OH2
Mahmood, K1
Khan, AM1
Ramanan, AV1
Martin, K1
McAvoy, BR1
Tobin, CL2
Akingbola, OA1
Singh, D1
Kleinman, JA1
Frieberg, EM1
Merchant, VA1
Benmoussa, J1
Chevenon, M1
Nandi, M1
Forlenza, TJ1
Nfonoyim, J1
Arens, A1
Smollin, C1
Ghannoum, M1
Kazim, S1
Grunbaum, AM1
Villeneuve, E1
Gosselin, S1
Quiroga, B1
Basterrechea, MÁ1
Fernández-Francés, J1
de Arriba, G1
Kamour, A1
Crichton, S1
Cooper, G1
Lupton, DJ1
Eddleston, M1
Vale, JA1
Thompson, JP1
Thomas, SH1
Kanabar, DJ1
Lamkin, S1
Fraiz, A1
Thomson, AD1
Weltman, MD1
Frei, MY1
Nielsen, S1
Dobbin, MD1
McDonough, MA1
Argentieri, J1
Morrone, K1
Pollack, Y1
Pini, LA1
Guerzoni, S1
Cainazzo, MM1
Ferrari, A1
Sarchielli, P1
Tiraferri, I1
Ciccarese, M1
Zappaterra, M1
McWhirter, KA1
Jones, RB1
Selbst, SM1
Osterhoudt, K1
Stevens, A1
Dodd, MD1
Graham, CA1
Kisely, SR1
Lawrence, D1
Preston, NJ1
Volans, G1
Monaghan, J2
Colbridge, M1
McGlennan, A1
Esler, M1
Stocks, G1
Pandit, V1
Mandal, NG1
Clarke, SF1
Arepalli, N1
Armstrong, C1
Dargan, PI2
Wazaify, M1
Kennedy, S1
Hughes, CM1
McElnay, JC1
Wood, DM1
Streete, P1
Jones, AL1
Magill, P1
Ridgway, PF1
Conlon, KC1
Neary, P1
Bilenko, N1
Tessler, H1
Okbe, R1
Press, J1
Gorodischer, R1
Nelson, H1
Katz, D1
Dunn, T1
Singh, G1
Voigt, M1
Whitaker, E1
Thomsen, D1
Marchei, E1
Pellegrini, M1
Pichini, S1
Martín, I1
García-Algar, O1
Vall, O1
Holubek, W1
Stolbach, A1
Nurok, S1
Lopez, O1
Wetter, A1
Nelson, L1
Manini, AF1
Raspberry, D1
Hoffman, RS1
Nelson, LS1
Kim, J1
Gazarian, M1
Verjee, Z1
Johnson, D1
Olsen, KM1
Gurley, BJ1
Davis, GA1
Archer, SR1
Ma, FH1
Ackerman, BH1
Wolfe, TR1
Le, HT1
Bosse, GM1
Tsai, Y1
Takayasu, T1
Nishigami, J1
Ohshima, T1
Lin, Z1
Kondo, T1
Nakaya, T1
Sawaguchi, T1
Nagano, T1
McCune, KH1
O'Brien, CJ1
Halpern, SM1
Fitzpatrick, R1
Volans, GN1
Downie, A1
Ali, A1
Bell, D1
Kunsman, GW1
Rohrig, TP1
Zuckerman, GB1
Uy, CC1
Zecca, TC1
al-Harbi, NN1
Domrongkitchaiporn, S1
Lirenman, DS1
Rainsford, KD1
Roberts, SC1
Brown, S1
Block, S1
Villar, D1
Buck, WB1
Gonzalez, JM1
Cimpello, LB1
Craig, S1
Lawrence, E1
Baker, MD1
Ritter, A1
Eskin, B1
Gaul, C1
Heckmann, JG1
Druschky, A1
Schöcklmann, H1
Neundörfer, B1
Erbguth, F1
Seifert, SA1
Bronstein, AC1
McGuire, T1
Easley, RB1
Altemeier, WA1
Laurent, S1
Rahier, J1
Geubel, AP1
Lerut, J1
Horsmans, Y1
Gunn, VL1
Taha, SH1
Liebelt, EL1
Serwint, JR1
Appu, S1
Thompson, G1
Balit, CR1
Peat, J1
Dawson, AH1
Whyte, IM1
Strain, WD1
Lye, M1
Hall, AH1
Smolinske, SC1
Stover, B1
Conrad, FL1
Rumack, BH1
Bright, TP1
McNulty, CJ1
Mack, RB1
Perazella, MA1
Buller, GK1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815]51 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294]52 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721]Phase 2/Phase 350 participants (Actual)Interventional2015-07-31Completed
Comparison of Supportive Therapies for Symptom Relief From Pediatric Upper Respiratory Infections (URIs)[NCT01814293]0 participants (Actual)Interventional2013-05-31Withdrawn (stopped due to loss of funding. No data was collected.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

8 reviews available for ibuprofen and Drug Overdose

ArticleYear
Intentional overdose of azathioprine in a patient with systemic lupus erythematosus.
    Scottish medical journal, 2013, Volume: 58, Issue:4

    Topics: Acetaminophen; Adolescent; Affective Disorders, Psychotic; Anti-Inflammatory Agents, Non-Steroidal;

2013
A clinical and safety review of paracetamol and ibuprofen in children.
    Inflammopharmacology, 2017, Volume: 25, Issue:1

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Drug Overdo

2017
Acetaminophen and Ibuprofen overdosage.
    Pediatrics in review, 2012, Volume: 33, Issue:4

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Chemical and Drug Induced Live

2012
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen overdose.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Drug Overdose; Humans; Ib

2003
Ibuprofen toxicity. A review of adverse reactions and overdose.
    Adverse drug reactions and toxicological reviews, 1993,Summer, Volume: 12, Issue:2

    Topics: Adult; Cardiovascular System; Central Nervous System; Child; Digestive System; Drug Overdose; Humans

1993
Ibuprofen and paracetamol: relative safety in non-prescription dosages.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:4

    Topics: Acetaminophen; Aged; Aging; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents

1997
Ibuprofen, aspirin and acetaminophen toxicosis and treatment in dogs and cats.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:3

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin;

1998
[Renal tubular acidosis with severe hypokalemic tetraparesis after ibuprofen intake].
    Deutsche medizinische Wochenschrift (1946), 1999, Apr-23, Volume: 124, Issue:16

    Topics: Acidosis, Renal Tubular; Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Di

1999

Trials

2 trials available for ibuprofen and Drug Overdose

ArticleYear
Nabilone for the treatment of medication overuse headache: results of a preliminary double-blind, active-controlled, randomized trial.
    The journal of headache and pain, 2012, Volume: 13, Issue:8

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Anti-Anxiety Agents; Cross-Over Studies; Double-Blind Method;

2012
Comparison of fluid volumes with whole bowel irrigation in a simulated overdose of ibuprofen.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:3

    Topics: Adult; Drug Overdose; Humans; Ibuprofen; Intestines; Male; Polyethylene Glycols; Prospective Studies

1995

Other Studies

64 other studies available for ibuprofen and Drug Overdose

ArticleYear
Lactic acidosis and multisystem organ failure following ibuprofen overdose requiring haemodialysis.
    BMJ case reports, 2022, Feb-07, Volume: 15, Issue:2

    Topics: Acidosis, Lactic; Adolescent; Child; Continuous Renal Replacement Therapy; Drug Overdose; Humans; Ib

2022
Duloxetine overdose causes sympathomimetic and serotonin toxicity without major complications.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9

    Topics: Acetaminophen; Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coma; Diazepam; Droperidol; Drug

2022
Controlling drug release by introducing lipase inhibitor within a lipid formulation.
    International journal of pharmaceutics, 2022, Jul-25, Volume: 623

    Topics: Administration, Oral; Animals; Delayed-Action Preparations; Drug Liberation; Drug Overdose; Ibuprofe

2022
Outcomes of nonsteroidal anti-inflammatory drug toxicosis treated with therapeutic plasma exchange in 62 dogs.
    Journal of veterinary internal medicine, 2022, Volume: 36, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Drug Overdose; Ibuprofen; Napr

2022
Lactic acidosis and multisystem organ failure following ibuprofen overdose requiring haemodialysis.
    Drug and therapeutics bulletin, 2023, Volume: 61, Issue:7

    Topics: Acidosis, Lactic; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Humans; Hypoglycem

2023
Treatment of ibuprofen intoxication in a dog via therapeutic plasma exchange.
    Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2017, Volume: 27, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Drug Overdose; Humans; Ibuprof

2017
Ibuprofen plasma concentration profile in deliberate ibuprofen overdose with circulatory depression treated with therapeutic plasma exchange: a case report.
    BMC pharmacology & toxicology, 2017, 12-12, Volume: 18, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Ibuprofen; Male; Middle Aged; Plasma

2017
Flow Restrictors and Reduction of Accidental Ingestions of Over-the-Counter Medications.
    American journal of preventive medicine, 2019, Volume: 56, Issue:6

    Topics: Accidents; Acetaminophen; Age Factors; Antitussive Agents; Child, Preschool; Diphenhydramine; Drug O

2019
Fatal misuse of codeine-ibuprofen analgesics in Victoria, Australia.
    The Medical journal of Australia, 2013, Sep-02, Volume: 199, Issue:5

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Drug Overdose; Female; Humans;

2013
Fatal misuse of codeine-ibuprofen analgesics in Victoria, Australia.
    The Medical journal of Australia, 2014, Feb-17, Volume: 200, Issue:3

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Drug Overdose; Female; Humans;

2014
Fatal misuse of codeine-ibuprofen analgesics in Victoria, Australia. In reply.
    The Medical journal of Australia, 2014, Feb-17, Volume: 200, Issue:3

    Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Drug Overdose; Female; Humans;

2014
Functional adrenal insufficiency complicating an overdose of naproxen and ibuprofen.
    Clinical pediatrics, 2015, Volume: 54, Issue:1

    Topics: Acidosis; Adolescent; Adrenal Insufficiency; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non

2015
A prescription for pain relief.
    The Journal of the Michigan Dental Association, 2014, Volume: 96, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Overdose; Female; Hu

2014
Ibuprofen-induced thrombotic thrombocytopenic purpura.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Ibuprofen; Male; Purpura, Thr

2016
Case Files of the University of California, San Francisco Medical Toxicology Fellowship: Seizures and a Persistent Anion Gap Metabolic Acidosis.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose;

2016
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Coma; Drug Overdose; Emergency Service,

2016
Diffuse alveolar damage and acute kidney injury induced by abusive use of non-steroidal anti-inflammatory drugs: a new and atypical renopulmonary syndrome?
    Internal medicine journal, 2016, Volume: 46, Issue:5

    Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Hemorrhage; Humans; Ibu

2016
Central nervous system toxicity of mefenamic acid overdose compared with other NSAIDs: an analysis of cases reported to the United Kingdom National Poisons Information Service.
    British journal of clinical pharmacology, 2017, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Ch

2017
An acid/base disturbance from ibuprofen toxicity.
    Journal of emergency nursing, 2009, Volume: 35, Issue:6

    Topics: Acid-Base Imbalance; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Ibuprofe

2009
Electronic images of the month. Severe duodenitis after massive chronic Ibuprofen overdose.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:11

    Topics: Adult; Drug Overdose; Duodenitis; Endoscopy, Gastrointestinal; Humans; Ibuprofen; Intestinal Mucosa;

2010
Serious morbidity associated with misuse of over-the-counter codeine-ibuprofen analgesics: a series of 27 cases.
    The Medical journal of Australia, 2010, Sep-06, Volume: 193, Issue:5

    Topics: Adult; Analgesics; Codeine; Drug Combinations; Drug Overdose; Female; Humans; Ibuprofen; Incidence;

2010
Misuse of codeine-containing combination analgesics.
    The Medical journal of Australia, 2011, May-02, Volume: 194, Issue:9

    Topics: Adult; Analgesics; Codeine; Drug Overdose; Drug Therapy, Combination; Female; Humans; Ibuprofen; Mal

2011
Accidental overdose of proprietary branded, combination analgesics available over the counter.
    British journal of hospital medicine (London, England : 2005), 2012, Volume: 73, Issue:11

    Topics: Acidosis; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Codeine; Di

2012
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2012, Volume: 28, Issue:12

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Adult; Aortic Aneurysm; Aortic Dissection; Appendicitis;

2012
Paracetamol recall: a natural experiment influencing analgesic poisoning.
    The Medical journal of Australia, 2002, Jun-03, Volume: 176, Issue:11

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Australia; Drug and Narcotic Control; Drug Overdose; Humans

2002
Unintentional overdose of analgesia secondary to acute dental pain.
    British dental journal, 2002, Aug-24, Volume: 193, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents,

2002
The effect of recalling paracetamol on hospital admissions for poisoning in Western Australia.
    The Medical journal of Australia, 2003, Jan-20, Volume: 178, Issue:2

    Topics: Accidents, Home; Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; A

2003
PFA-100 and regional analgesia in a parturient after ibuprofen overdose.
    British journal of anaesthesia, 2004, Volume: 92, Issue:5

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Contraindications; Dru

2004
PFA-100(R) and regional analgesia.
    British journal of anaesthesia, 2004, Volume: 93, Issue:3

    Topics: Analgesia, Epidural; Analgesics, Non-Narcotic; Contraindications; Drug Overdose; Humans; Ibuprofen;

2004
Duodenal perforation after ibuprofen overdose.
    Journal of toxicology. Clinical toxicology, 2004, Volume: 42, Issue:7

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Duodenal Diseases; Duodenal Ulce

2004
Prevalence of over-the-counter drug-related overdoses at Accident and Emergency departments in Northern Ireland--a retrospective evaluation.
    Journal of clinical pharmacy and therapeutics, 2005, Volume: 30, Issue:1

    Topics: Acetaminophen; Age Factors; Alcohol Drinking; Aspirin; Data Collection; Databases as Topic; Drug Com

2005
Fatality after deliberate ingestion of sustained-release ibuprofen: a case report.
    Critical care (London, England), 2006, Volume: 10, Issue:2

    Topics: Adult; Delayed-Action Preparations; Drug Overdose; Fatal Outcome; Female; Humans; Ibuprofen; Suicide

2006
A case of probable ibuprofen-induced acute pancreatitis.
    JOP : Journal of the pancreas, 2006, May-09, Volume: 7, Issue:3

    Topics: Acute Disease; Adolescent; Drug Overdose; Humans; Ibuprofen; Male; Pancreatitis

2006
Determinants of antipyretic misuse in children up to 5 years of age: a cross-sectional study.
    Clinical therapeutics, 2006, Volume: 28, Issue:5

    Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid

2006
Rhabdomyolysis and necrotic bowel after acetaminophen and ibuprofen overdose.
    Pharmacotherapy, 2007, Volume: 27, Issue:4

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Blood Chemical Analysis; Drug Overdose; Humans; Ibup

2007
Are false-positive phencyclidine immunoassay instant-view multi-test results caused by overdose concentrations of Ibuprofen, metamizol, and dextromethorphan?
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Child, Preschool; Dextromethorphan; Dia

2007
A report of two deaths from massive ibuprofen ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:2

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Fatal Outcome; Female; Humans; I

2007
QT prolongation and Torsades de Pointes following overdose of ziprasidone and amantadine.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2007, Volume: 3, Issue:4

    Topics: Adult; Amantadine; Analgesics, Non-Narcotic; Antipsychotic Agents; Drug Overdose; Drug Therapy, Comb

2007
Acute renal insufficiency in ibuprofen overdose.
    Pediatric emergency care, 1995, Volume: 11, Issue:2

    Topics: Acute Kidney Injury; Child, Preschool; Drug Overdose; Humans; Ibuprofen; Male

1995
Ibuprofen overdose.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:3

    Topics: Adult; Drug Overdose; Humans; Ibuprofen; Male

1995
Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adult; Charcoal; Citrates; Citric Acid; Drug Overdose; Humans; Ibupro

1994
[A fatal case due to intoxication with seven drugs detected by GC-MS and TDx methods].
    Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1993, Volume: 47, Issue:1

    Topics: Acetaminophen; Adult; Bromisovalum; Caffeine; Drug Overdose; Female; Fluorescent Antibody Technique;

1993
Atrial fibrillation induced by ibuprofen overdose.
    Postgraduate medical journal, 1993, Volume: 69, Issue:810

    Topics: Adult; Atrial Fibrillation; Drug Overdose; Humans; Ibuprofen; Male

1993
Severe metabolic acidosis complicating massive ibuprofen overdose.
    Postgraduate medical journal, 1993, Volume: 69, Issue:813

    Topics: Acidosis; Adult; Charcoal; Drug Overdose; Humans; Ibuprofen; Male

1993
Tissue distribution of ibuprofen in a fatal overdose.
    The American journal of forensic medicine and pathology, 1993, Volume: 14, Issue:1

    Topics: Adult; Brain Chemistry; Chromatography, High Pressure Liquid; Drug Overdose; Humans; Ibuprofen; Live

1993
Shock, metabolic acidosis, and coma following ibuprofen overdose in a child.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:9

    Topics: Acidosis; Child; Coma; Critical Care; Drug Overdose; Humans; Ibuprofen; Male; Shock

1995
Management of ibuprofen overdose.
    Pediatrics in review, 1997, Volume: 18, Issue:3

    Topics: Drug Overdose; Humans; Ibuprofen

1997
Hypocalcemia and hypomagnesemia after ibuprofen overdose.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:4

    Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Hypocalcemia; Ibuprofen; I

1997
Ibuprofen and/or acetaminophen: what price for "euthermia"?
    The Journal of pediatrics, 1997, Volume: 131, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmac

1997
A calcium channel blocker and ibuprofen overdose.
    Current opinion in pediatrics, 1998, Volume: 10, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Calcium Channel Blockers;

1998
Ibuprofen overdose presenting with severe agitation and hypothermia.
    The American journal of emergency medicine, 1998, Volume: 16, Issue:5

    Topics: Adolescent; Akathisia, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Emergen

1998
Massive ibuprofen ingestion with survival.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:1

    Topics: Acidosis; Adolescent; Analgesics, Non-Narcotic; Coma; Drug Overdose; Female; Humans; Ibuprofen; Thro

2000
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.
    Pediatric emergency care, 2000, Volume: 16, Issue:1

    Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Central Nervous System; Central Nervou

2000
Subfulminant hepatitis requiring liver transplantation following ibuprofen overdose.
    Liver, 2000, Volume: 20, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Overdose; Fema

2000
Toxicity of over-the-counter cough and cold medications.
    Pediatrics, 2001, Volume: 108, Issue:3

    Topics: Acetaminophen; Antitussive Agents; Bradycardia; Brompheniramine; Cardiovascular Diseases; Child, Pre

2001
Acetaminophen toxicity in children.
    Pediatrics, 2001, Volume: 108, Issue:4

    Topics: Acetaminophen; Adult; Age Factors; Analgesics, Non-Narcotic; Charcoal; Child; Drug Overdose; Humans;

2001
Gangrenous ischaemic colitis following non-steroidal anti-inflammatory drug overdose.
    ANZ journal of surgery, 2001, Volume: 71, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Butylscopolammonium Bromide; Colitis, Ischemic; Colo

2001
Paracetamol recall: a natural experiment influencing analgesic poisoning.
    The Medical journal of Australia, 2002, Feb-18, Volume: 176, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Australia; Child; Drug and Narcotic Control; Drug

2002
Chronic pain, bereavement and overdose in a depressed elderly woman.
    Age and ageing, 2002, Volume: 31, Issue:3

    Topics: Acetaminophen; Aged; Aged, 80 and over; Aging; Aortic Aneurysm, Thoracic; Aspirin; Back Pain; Bereav

2002
Ibuprofen overdose in adults.
    Journal of toxicology. Clinical toxicology, 1992, Volume: 30, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Cathartics; Charcoal; Colorado; Drug Overdose; Follow-Up Stu

1992
Suspected central nervous system toxicity from inadvertent nonsteroidal antiinflammatory drug overdose.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System Diseases; Diclofenac; Drug Overdose;

1991
Which one is Hardy? Ibuprofen overdose.
    North Carolina medical journal, 1991, Volume: 52, Issue:5

    Topics: Child; Drug Overdose; Humans; Ibuprofen; Literature, Modern; Medicine in Literature

1991
Can ibuprofen cause acute renal failure in a normal individual? A case of acute overdose.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:5

    Topics: Drug Overdose; Female; Humans; Ibuprofen; Kidney Tubular Necrosis, Acute; Middle Aged; Urine

1991
Ibuprofen vs acetaminophen in children.
    The Medical letter on drugs and therapeutics, 1989, Dec-15, Volume: 31, Issue:807

    Topics: Acetaminophen; Child; Drug Overdose; Fever; Humans; Ibuprofen; Pain; Suspensions

1989