ibuprofen has been researched along with Delayed Effects, Prenatal Exposure in 19 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 7.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 7.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| "Ibuprofen exposure during the first trimester was associated with a decrease in birth weight of 79 grams (95% confidence interval -133 to -25 grams)." | 7.83 | Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O; Wood, M, 2016) |
| "Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1." | 7.81 | Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015) |
| " Up to the present day, several cases of severe and sometimes irreversible renal insufficiency have been described in neonates exposed to indomethacin prenatally or in the first days of life for treatment of patent ductus arteriosus (PDA)." | 4.81 | NSAID-induced nephrotoxicity from the fetus to the child. ( Cuzzolin, L; Dal Cerè, M; Fanos, V, 2001) |
| "Examine associations of acetaminophen and ibuprofen use during pregnancy and infancy with executive function and behaviour problems in children." | 3.96 | Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour. ( Bertoldi, AD; Cardenas, A; Hivert, MF; Oken, E; Rifas-Shiman, SL; Tiemeier, H, 2020) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 3.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 3.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| "Ibuprofen exposure during the first trimester was associated with a decrease in birth weight of 79 grams (95% confidence interval -133 to -25 grams)." | 3.83 | Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study. ( Nezvalová-Henriksen, K; Nordeng, H; Spigset, O; Wood, M, 2016) |
| "Unadjusted models showed an increased asthma risk in early childhood for higher infant acetaminophen (odds ratio [OR], 1." | 3.81 | Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. ( Bunyavanich, S; Camargo, CA; Gillman, MW; Gold, DR; Litonjua, AA; Rifas-Shiman, SL; Scirica, CV; Sordillo, JE; Weiss, ST, 2015) |
| " IBU blocked LPS-induced fever but did not block LPS-induced increases in plasma cytokines and corticosterone in the pregnant dam." | 3.75 | Effects of prenatal immune activation on hippocampal neurogenesis in the rat. ( Ashdown, H; Boksa, P; Cui, K; Luheshi, GN, 2009) |
| "We confirm by meconium analysis the results of previous studies that demonstrated that the use of NSAIDs during pregnancy, particularly aspirin, ibuprofen, and naproxen, is high; is grossly underestimated by maternal history; and is significantly associated with PPHN." | 3.71 | Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn. ( Alano, MA; Konduri, GG; Ngougmna, E; Ostrea, EM, 2001) |
| " After culture, embryo morphological and developmental parameters were documented using standardized scoring systems at each dosage concentration." | 2.82 | Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system. ( Leung, BW; Leung, TY; Moungmaithong, S; Poon, LC; Sahota, DS; Wang, CC, 2022) |
| "Ibuprofen is a non-selective cyclooxygenase (COX) inhibitor with analgesic, antipyretic and antiinflammatory activity." | 2.41 | [Current opinions on embryotoxic and teratogenic effects of ibuprofen]. ( Bełzek, A; Burdan, F, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Moungmaithong, S | 1 |
| Leung, BW | 1 |
| Sahota, DS | 1 |
| Wang, CC | 1 |
| Leung, TY | 1 |
| Poon, LC | 1 |
| Rossitto, M | 2 |
| Ollivier, M | 1 |
| Déjardin, S | 1 |
| Pruvost, A | 2 |
| Brun, C | 1 |
| Marchive, C | 2 |
| Nguyen, AL | 1 |
| Ghettas, A | 2 |
| Keime, C | 1 |
| de Massy, B | 1 |
| Poulat, F | 2 |
| Philibert, P | 2 |
| Boizet-Bonhoure, B | 2 |
| Rifas-Shiman, SL | 2 |
| Cardenas, A | 1 |
| Hivert, MF | 1 |
| Tiemeier, H | 1 |
| Bertoldi, AD | 1 |
| Oken, E | 1 |
| Balin, PDS | 1 |
| Jorge, BC | 1 |
| Leite, ARR | 1 |
| Borges, CS | 1 |
| Oba, E | 1 |
| Silva, EJR | 1 |
| de Barros, AL | 1 |
| Horta-Júnior, JAC | 1 |
| Arena, AC | 1 |
| Petersen, TG | 1 |
| Liew, Z | 1 |
| Andersen, AN | 1 |
| Andersen, GL | 1 |
| Andersen, PK | 1 |
| Martinussen, T | 1 |
| Olsen, J | 2 |
| Rebordosa, C | 2 |
| Tollånes, MC | 1 |
| Uldall, P | 1 |
| Wilcox, AJ | 1 |
| Strandberg-Larsen, K | 1 |
| Sellem, E | 1 |
| Badiou, S | 1 |
| Sutra, T | 1 |
| Sordillo, JE | 1 |
| Scirica, CV | 1 |
| Gillman, MW | 1 |
| Bunyavanich, S | 1 |
| Camargo, CA | 1 |
| Weiss, ST | 1 |
| Gold, DR | 1 |
| Litonjua, AA | 1 |
| Shaheen, SO | 1 |
| Kristensen, DM | 2 |
| Mazaud-Guittot, S | 1 |
| Gaudriault, P | 1 |
| Lesné, L | 2 |
| Serrano, T | 1 |
| Main, KM | 2 |
| Jégou, B | 2 |
| Nezvalová-Henriksen, K | 1 |
| Wood, M | 1 |
| Spigset, O | 1 |
| Nordeng, H | 1 |
| Cui, K | 1 |
| Ashdown, H | 1 |
| Luheshi, GN | 1 |
| Boksa, P | 1 |
| Hass, U | 1 |
| Lottrup, G | 1 |
| Jacobsen, PR | 1 |
| Desdoits-Lethimonier, C | 1 |
| Boberg, J | 1 |
| Petersen, JH | 1 |
| Toppari, J | 1 |
| Jensen, TK | 1 |
| Brunak, S | 1 |
| Skakkebaek, NE | 1 |
| Nellemann, C | 1 |
| Leffers, H | 1 |
| Vieux, R | 1 |
| Fresson, J | 1 |
| Guillemin, F | 1 |
| Hascoet, JM | 1 |
| Jensen, MS | 1 |
| Henriksen, TB | 1 |
| Thulstrup, AM | 1 |
| Toft, G | 1 |
| Sørensen, HT | 1 |
| Bonde, JP | 1 |
| Wen, SW | 1 |
| Yang, T | 1 |
| Krewski, D | 1 |
| Yang, Q | 1 |
| Nimrod, C | 1 |
| Garner, P | 1 |
| Fraser, W | 1 |
| Olatunbosun, O | 1 |
| Walker, MC | 1 |
| Takizawa, T | 1 |
| Ikeda, Y | 1 |
| Kawahata, M | 1 |
| Togashi, H | 1 |
| Yamamoto, M | 1 |
| Arishima, K | 1 |
| Masaoka, T | 1 |
| Cuzzolin, L | 1 |
| Dal Cerè, M | 1 |
| Fanos, V | 1 |
| Alano, MA | 1 |
| Ngougmna, E | 1 |
| Ostrea, EM | 1 |
| Konduri, GG | 1 |
| Burdan, F | 1 |
| Bełzek, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Copenhagen Analgesic Study[NCT04369222] | 600 participants (Anticipated) | Observational | 2020-03-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for ibuprofen and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Assessment of embryo morphology following perinatal exposure to aspirin, ibuprofen and paracetamol using whole embryo culture system.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Humans; Ibuprofen; | 2022 |
Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Commerce; | 2016 |
NSAID-induced nephrotoxicity from the fetus to the child.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Ductus Arteriosus, Patent; Female; | 2001 |
[Current opinions on embryotoxic and teratogenic effects of ibuprofen].
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastroschisis; Humans; | 2001 |
15 other studies available for ibuprofen and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.
Topics: Acetaminophen; Aging; Animals; Animals, Newborn; Cell Proliferation; Female; Fertility; Forkhead Box | 2019 |
Associations of prenatal or infant exposure to acetaminophen or ibuprofen with mid-childhood executive function and behaviour.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child Behavior; Child Behavior Disorder | 2020 |
Maternal exposure to ibuprofen can affect the programming of the hypothalamus of the male offspring.
Topics: Animals; Brain; Female; Hypothalamus; Ibuprofen; Male; Maternal Exposure; Pregnancy; Prenatal Exposu | 2020 |
Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cerebral Palsy; Cohort Studies; Female; Hum | 2018 |
Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Embryo, M | 2019 |
Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chi | 2015 |
Acetaminophen and childhood asthma: pill-popping at our peril?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Female; Hu | 2015 |
Association of Prenatal Ibuprofen Exposure with Birth Weight and Gestational Age: A Population-Based Sibling Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Child; Female; Gestational Age; Humans | 2016 |
Effects of prenatal immune activation on hippocampal neurogenesis in the rat.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroida | 2009 |
Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cohort Studies; Cryptorchidism; Female; Humans; Ibuprof | 2011 |
Perinatal drug exposure and renal function in very preterm infants.
Topics: Analgesics, Non-Narcotic; Female; Gestational Age; Glomerular Filtration Rate; Humans; Ibuprofen; In | 2011 |
Analgesics during pregnancy and cryptorchidism: additional analyses.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Aspirin; Cryptorchidism; Cyclooxygenase Inhibitors; Female; | 2011 |
Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population.
Topics: Adult; Albuterol; Contraceptives, Oral; Cross-Sectional Studies; Drug Prescriptions; Drug-Related Si | 2008 |
Increased ductal responsiveness to PGE2 after maternal treatment with aspirin and ibuprofen.
Topics: Administration, Oral; Animals; Animals, Newborn; Aspirin; Cesarean Section; Dinoprostone; Ductus Art | 1998 |
Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bronchodilator Agents; Extracorporeal Membrane Oxy | 2001 |