ibuprofen has been researched along with Critical Illness in 5 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hospitalized patients are often unable to ingest or tolerate oral antipyretics and recently an aqueous formulation of intravenous (IV) ibuprofen was approved by the US-FDA for the reduction of fever in adults." | 9.14 | A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults. ( Arons, MM; Guntupalli, KK; Morris, PE; Promes, JT; Wright, PE, 2010) |
| "Hospitalized patients are often unable to ingest or tolerate oral antipyretics and recently an aqueous formulation of intravenous (IV) ibuprofen was approved by the US-FDA for the reduction of fever in adults." | 5.14 | A multi-center, randomized, double-blind, parallel, placebo-controlled trial to evaluate the efficacy, safety, and pharmacokinetics of intravenous ibuprofen for the treatment of fever in critically ill and non-critically ill adults. ( Arons, MM; Guntupalli, KK; Morris, PE; Promes, JT; Wright, PE, 2010) |
| "Renal tubular acidosis is an underreported complication of ibuprofen misuse, and can result in life-threatening hypokalaemia." | 1.37 | Life-threatening hypokalaemia associated with ibuprofen-induced renal tubular acidosis. ( Coleman, PL; Gan, SK; Loh, NK; Morgan, DJ; Ng, JL; Ong, GS; Prentice, D, 2011) |
| "Fever is a common occurrence in the intensive care unit, and pharmacologic approaches are limited, particularly in patients unable to tolerate enteral medications." | 1.36 | Hot times in the intensive care unit. ( Abraham, E, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moffett, BS | 1 |
| Gutierrez, K | 1 |
| Davis, K | 1 |
| Sigdel, B | 1 |
| Strobel, N | 1 |
| Uber, AM | 1 |
| Montez-Rath, ME | 1 |
| Kwiatkowski, DM | 1 |
| Krawczeski, CD | 1 |
| Sutherland, SM | 1 |
| Morris, PE | 1 |
| Promes, JT | 1 |
| Guntupalli, KK | 1 |
| Wright, PE | 1 |
| Arons, MM | 1 |
| Abraham, E | 1 |
| Ng, JL | 1 |
| Morgan, DJ | 1 |
| Loh, NK | 1 |
| Gan, SK | 1 |
| Coleman, PL | 1 |
| Ong, GS | 1 |
| Prentice, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Assessment of the Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic[NCT02268955] | 22 participants (Actual) | Interventional | 2014-09-09 | Completed | |||
| A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755] | 62 participants (Actual) | Interventional | 2017-07-01 | Completed | |||
| A Multicenter, Randomized, Double-blind, Parallel, Placebo-controlled Trial To Evaluate The Efficacy, Safety, and Pharmacokinetics of Ibuprofen Injection in Adult Febrile Patients[NCT01131000] | Phase 3 | 123 participants (Actual) | Interventional | 2002-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Pain is measured on a visual analog scale 0=no pain and 10=worst pain imaginable. (NCT02268955)
Timeframe: 120 minutes post medication administration
| Intervention | score on a scale (Median) |
|---|---|
| Control Group: Adults Age 18-55 Years | 3.0 |
| IV Ibuprofen: Adults Age 18-55 Years | 0.3 |
1 trial available for ibuprofen and Critical Illness
4 other studies available for ibuprofen and Critical Illness
| Article | Year |
|---|---|
Antipyretic Efficacy of Acetaminophen and Ibuprofen in Critically Ill Pediatric Patients.
Topics: Acetaminophen; Antipyretics; Body Temperature; Child; Child, Preschool; Critical Illness; Female; Fe | 2019 |
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Crit | 2018 |
Hot times in the intensive care unit.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Critical Illness; Fever; Humans; Ibuprofen; Infusions, Intr | 2010 |
Life-threatening hypokalaemia associated with ibuprofen-induced renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Adult; Anti-Inflammatory Agents, Non-Steroidal; Critical Illness; Dose-Resp | 2011 |