Page last updated: 2024-10-28

ibuprofen and Chronic Disease

ibuprofen has been researched along with Chronic Disease in 79 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"Ibuprofen/paracetamol combination analgesia, at non-prescription doses, confers modest short-term benefits for knee pain/osteoarthritis."9.15A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain. ( Aspley, S; Doherty, M; Gibb, I; Goulder, M; Hawkey, C; Hill, N; Reader, S, 2011)
"The aim of the study was to evaluate a novel foam dressing with continuous low-level release of ibuprofen (Biatain-Ibu foam dressing, Coloplast A/S, Humlebaek, Denmark) in persons with leg ulcers compared to local best practice."9.12A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice). ( Coutts, P; Fierheller, M; Sibbald, RG; Woo, K, 2007)
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache."9.12Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007)
"An early lowering of the serum NO metabolite levels after ibuprofen-arginine administration could be detected in patients with chronic low back pain."9.12Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747). ( Gay, RE; Gay, S; Michel, BA; Sprott, H, 2006)
"To evaluate the efficacy of a terpene mixture (rowatinex) compared to ibuprofen, patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were randomly selected to either receive rowatinex 200 mg t."9.12Preliminary experience with a terpene mixture versus ibuprofen for treatment of category III chronic prostatitis/chronic pelvic pain syndrome. ( Cho, YH; Ha, US; Kim, SW; Lee, CB; Lee, SJ, 2006)
"This study will provide new evidence on the overall costs and benefits of treating chronic knee pain with either oral or topical ibuprofen."9.11TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052]. ( Ashby, D; Cross, PL; Harding, G; Hennessy, EM; Letley, L; Parsons, S; Spencer, AE; Underwood, M, 2005)
"5 mg and ibuprofen 200 mg with that of combination codeine 30 mg and acetaminophen 300 mg for the treatment of chronic pain."9.09Combination hydrocodone and ibuprofen versus combination codeine and acetaminophen for the treatment of chronic pain. ( Damask, MJ; de Padova, A; Doyle, RT; Jiang, JG; Landau, CJ; Morris, E; Palangio, M, 2000)
"In short-term, symptomatic treatment of osteoarthritis of the knee, the efficacy of acetaminophen was similar to that of ibuprofen, whether the latter was administered in an analgesic or an antiinflammatory dose."9.07Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. ( Bradley, JD; Brandt, KD; Kalasinski, LA; Katz, BP; Ryan, SI, 1991)
"A 57-year-old woman believed that ibuprofen, prescribed for back pain, improved her idiopathic chronic cough that had been resistant to inhaled and oral corticosteroids."9.07Chronic cough responsive to ibuprofen. ( Dales, RE; Lunau, MA; Schweitzer, I; Tierney, MG, 1992)
"Thirty subjects with chronic moderate to severe pain who were receiving oxycodone/acetaminophen (oxy/APAP) for analgesia were initially evaluated for at least 7 days for oxy/APAP requirements for pain control."9.06The combination of ibuprofen and oxycodone/acetaminophen in the management of chronic cancer pain. ( Drew, J; Stambaugh, JE, 1988)
" We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS."5.56Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020)
"Ibuprofen did not increase the pulmonary burden of Pseudomonas, and the ibuprofen-treated infected animals gained weight better than placebo-treated controls."5.28Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. ( Davis, PB; Konstan, MW; Vargo, KM, 1990)
"The objective of this study was to evaluate the benefit of a seven-day buprenorphine transdermal patch for patients with chronic musculoskeletal pain previously receiving long-term treatment with ibuprofen or diclofenac alone."5.15[Application of a seven-day buprenorphine transdermal patch in multimorbid patients on long-term ibuprofen or diclofenac]. ( Böhme, K; Heckes, B; Thomitzek, K, 2011)
"Ibuprofen/paracetamol combination analgesia, at non-prescription doses, confers modest short-term benefits for knee pain/osteoarthritis."5.15A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain. ( Aspley, S; Doherty, M; Gibb, I; Goulder, M; Hawkey, C; Hill, N; Reader, S, 2011)
"An early lowering of the serum NO metabolite levels after ibuprofen-arginine administration could be detected in patients with chronic low back pain."5.12Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747). ( Gay, RE; Gay, S; Michel, BA; Sprott, H, 2006)
" Mirtazapine has a prophylactic and ibuprofen an acute effect in tension-type headache."5.12Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache. ( Ashina, S; Bendtsen, L; Buchgreitz, L; Jensen, R, 2007)
"The aim of the study was to evaluate a novel foam dressing with continuous low-level release of ibuprofen (Biatain-Ibu foam dressing, Coloplast A/S, Humlebaek, Denmark) in persons with leg ulcers compared to local best practice."5.12A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice). ( Coutts, P; Fierheller, M; Sibbald, RG; Woo, K, 2007)
"To evaluate the efficacy of a terpene mixture (rowatinex) compared to ibuprofen, patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were randomly selected to either receive rowatinex 200 mg t."5.12Preliminary experience with a terpene mixture versus ibuprofen for treatment of category III chronic prostatitis/chronic pelvic pain syndrome. ( Cho, YH; Ha, US; Kim, SW; Lee, CB; Lee, SJ, 2006)
"The aim of this controlled clinical trial was to investigate the analgesic efficacy and tolerability of ibuprofen arginine in patients with mild-to-moderate periodontitis during and after non-surgical periodontal treatment."5.12Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial. ( Bernasconi, C; Bless, K; Ettlin, A; Ettlin, DA; Gallo, LM; Palla, S; Puhan, M; Tillmann, HC, 2006)
"This study will provide new evidence on the overall costs and benefits of treating chronic knee pain with either oral or topical ibuprofen."5.11TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052]. ( Ashby, D; Cross, PL; Harding, G; Hennessy, EM; Letley, L; Parsons, S; Spencer, AE; Underwood, M, 2005)
"12-week within-patient, randomised, double-blind, placebo-controlled, crossover comparison of ibuprofen with paracetamol for osteoarthritis, involving three pairs of two-week treatment periods for each participating patient."5.09Preliminary experiences with a single-patient trials service in general practice. ( Clavarino, A; Del Mar, CB; Duggan, CM; Glasziou, PP; Nikles, CJ; Yelland, MJ, 2000)
"5 mg and ibuprofen 200 mg with that of combination codeine 30 mg and acetaminophen 300 mg for the treatment of chronic pain."5.09Combination hydrocodone and ibuprofen versus combination codeine and acetaminophen for the treatment of chronic pain. ( Damask, MJ; de Padova, A; Doyle, RT; Jiang, JG; Landau, CJ; Morris, E; Palangio, M, 2000)
"This clinical trial investigated the influence of short-term ibuprofen therapy on the early phase of the treatment of adult chronic periodontitis."5.07The effect of systemic ibuprofen on gingival inflammation in humans. ( Taiyeb Ali, TB; Waite, IM, 1993)
"A 57-year-old woman believed that ibuprofen, prescribed for back pain, improved her idiopathic chronic cough that had been resistant to inhaled and oral corticosteroids."5.07Chronic cough responsive to ibuprofen. ( Dales, RE; Lunau, MA; Schweitzer, I; Tierney, MG, 1992)
"In short-term, symptomatic treatment of osteoarthritis of the knee, the efficacy of acetaminophen was similar to that of ibuprofen, whether the latter was administered in an analgesic or an antiinflammatory dose."5.07Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. ( Bradley, JD; Brandt, KD; Kalasinski, LA; Katz, BP; Ryan, SI, 1991)
"A randomized, controlled clinical trial was conducted in 76 children to evaluate the efficacy of trimethoprim-sulfamethoxazole for 4 weeks, prednisone for 2 weeks and aluminum ibuprofen suspension for 2 weeks in resolving chronic otitis media with effusion which had persisted for more than 8 weeks."5.06A controlled trial comparing three treatments for chronic otitis media with effusion. ( Batalden, PB; Buran, DJ; Giebink, GS; Lassman, FM; Le, CT; Seltz, AE, 1990)
"Thirty subjects with chronic moderate to severe pain who were receiving oxycodone/acetaminophen (oxy/APAP) for analgesia were initially evaluated for at least 7 days for oxy/APAP requirements for pain control."5.06The combination of ibuprofen and oxycodone/acetaminophen in the management of chronic cancer pain. ( Drew, J; Stambaugh, JE, 1988)
"We know from adult randomised controlled trials that some NSAIDs, such as ibuprofen, naproxen, and aspirin, can be effective in certain chronic pain conditions."4.95Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. ( Anderson, B; Cooper, TE; Eccleston, C; Fisher, E; Wilkinson, NM, 2017)
"Though all non-narcotic analgesics have equivalent efficacy against tension-type headache, ibuprofen's generally favorable side-effect profile makes it a reasonable first choice."4.83Is any one analgesic superior for episodic tension-type headache? ( Berger, MY; Damen, L; Koes, BW; Merlijn, V; Passchier, J; Verhagen, AP, 2006)
"This case demonstrates the efficacy of ibuprofen in the treatment of the Schnitzler's syndrome."4.79[The Schnitzler syndrome as a cause of recurrent fever of unknown origin]. ( Maier, R; Nagel, HG; Reuther, G; Winckelmann, G, 1996)
" To investigate whether innate rodent burrowing is a useful alternative behavioural readout for assessment of analgesic efficacy, a complete Freund's adjuvant (CFA)-induced model of sub-chronic inflammation was used to compare the effects of naproxen, ibuprofen and pregabalin in weight-bearing (WB), open-field (OF) and burrowing assays."3.80Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation. ( Christoph, T; Leipelt, A; Pasqualon, T; Read, SJ; Robens, A; Rutten, K; Schiene, K, 2014)
" As inflammation has been involved in CIH-induced hypertension and chemosensory potentiation, we tested whether ibuprofen may block CB chemosensory and cardiorespiratory alterations induced by CIH in a rat model of OSA."3.78Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia. ( Del Rio, R; Iturriaga, R; Madrid, C; Moya, EA; Parga, MJ, 2012)
"Substituted thiazoles with different structural features were synthesized and screened for their anti-inflammatory activity in acute carrageenin induced rat paw edema model and chronic formalin induced rat paw edema model."3.742-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures. ( Franklin, PX; Nivsarkar, M; Padh, H; Pillai, AD; Rathod, PD; Sudarsanam, V; Vasu, KK; Yerande, S, 2008)
"The objective of the present study has been to advance knowledge of the gastric role played by the amino acid L-Arginine (L-Arg) in the evolution of a chronic gastric ulcer."3.73Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression. ( Bruseghini, L; Esteras, A; Illanes, M; Martín-Lacave, I; Motilva, V; Sánchez-Fidalgo, S, 2005)
" In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase."3.73COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005)
" Here, we evaluate the efficacy and tolerability of a new treatment option (suppositories) containing pollen extract in combination with hyaluronic acid and vitamins in the management of patients with CP/CPPS."3.11The efficacy and tolerability of pollen extract in combination with hyaluronic acid and vitamins in the management of patients affected by chronic prostatitis/chronic pelvic pain syndrome: a 26 weeks, randomized, controlled, single-blinded, phase III stud ( Bjerklund Johansen, TE; Bonkat, G; Cai, T; Cione, E; Gallelli, L; Mirone, V; Palmieri, A; Verze, P; Wagenlehner, FM, 2022)
" Adverse drug reactions may be renal, gastrointestinal, hematological, or immunologic."2.82Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years. ( Gorenflo, M; Saur, P; van den Anker, JN; van Dyk, M; Welzel, T; Ziesenitz, VC, 2022)
" Ibuprofen is associated with certain well-known gastrointestinal adverse effects that are related to dose and patient population."2.66Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review. ( Dowling, P; Paladini, A; Pergolizzi, JV; Varrassi, G, 2020)
" Particularly in older patients, long-term use of diuretics can lead to severe electrolyte imbalances, volume depletion, and falls."2.52Bilateral leg edema in an older woman. ( Pienaar, S; Roller-Wirnsberger, RE; Thaler, HW; Wirnsberger, G, 2015)
" We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS."1.56Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020)
"The consequences of chronic insufficient sleep for health remain uncertain."1.46Decreased alertness due to sleep loss increases pain sensitivity in mice. ( Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M, 2017)
"Colitis was induced in rats by an enema containing 2,4,6-trinitrobenzen sulfonic acid."1.32Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats. ( Ardid, D; Eschalier, A; Etienne, M; Jourdan, D; Millecamps, M, 2004)
" Although topical corticosteroids have been widely utilized in steroid-responsive dermatoses such as AD, their chronic use may be associated with significant side effects."1.32Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses. ( Hayashi, H; Inoue, Y; Isobe, M; Shiohara, T, 2003)
"Ibuprofen treatment decreased the raised level on day 21 and increased the reduced level on day 35."1.32Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat. ( Banerjee, M; Puri, A; Shukla, R; Srivastava, VM; Tripathi, LM, 2003)
"Ibuprofen did not increase the pulmonary burden of Pseudomonas, and the ibuprofen-treated infected animals gained weight better than placebo-treated controls."1.28Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. ( Davis, PB; Konstan, MW; Vargo, KM, 1990)
"An analysis of 100 consecutive cases of juvenile rheumatoid arthritis from South India revealed a male preponderance (62%), a lower incidence of the systemic onset variety (10%) and equal incidence of systemic features when compared with the West."1.28Pattern of rheumatic diseases in south India. IV. Clinical profile of juvenile rheumatoid arthritis. ( Chandrasekaran, AN; Krishnamurthy, V; Madhavan, R; Parthiban, M; Porkodi, R; Subramaniam, R, 1990)
"Treatment with ibuprofen or high-dose methylprednisolone after the first injection prevented or reduced vasospasm."1.27Prevention of chronic experimental cerebral vasospasm with ibuprofen and high-dose methylprednisolone. ( Chyatte, D; Rusch, N; Sundt, TM, 1983)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-19909 (11.39)18.7374
1990's17 (21.52)18.2507
2000's26 (32.91)29.6817
2010's20 (25.32)24.3611
2020's7 (8.86)2.80

Authors

AuthorsStudies
Franklin, PX1
Pillai, AD1
Rathod, PD1
Yerande, S1
Nivsarkar, M1
Padh, H1
Vasu, KK1
Sudarsanam, V1
Ziesenitz, VC1
Welzel, T1
van Dyk, M1
Saur, P1
Gorenflo, M1
van den Anker, JN1
Varrassi, G1
Pergolizzi, JV1
Dowling, P1
Paladini, A1
Miller, C1
Humphreys, IM1
Davis, GE1
Kaneko, S1
Shimizu, M1
Inoue, N1
Mizuta, M1
Yachie, A1
Mitra, S1
Scrivens, A1
von Kursell, AM1
Disher, T1
Toom, S1
Wolf, B1
Avula, A1
Peeke, S1
Becker, K1
Cai, T1
Gallelli, L1
Cione, E1
Verze, P1
Palmieri, A1
Mirone, V1
Bonkat, G1
Wagenlehner, FM1
Bjerklund Johansen, TE1
Alexandre, C1
Latremoliere, A1
Ferreira, A1
Miracca, G1
Yamamoto, M1
Scammell, TE1
Woolf, CJ1
Eccleston, C1
Cooper, TE1
Fisher, E1
Anderson, B1
Wilkinson, NM1
Umebayashi Zanoti, MD1
Megumi Sonobe, H1
Lima Ribeiro, SJ1
Minarelli Gaspar, AM1
Liu, SC1
Qiao, XF1
Tang, QX1
Li, XG1
Yang, JH1
Wang, TQ1
Xiao, YJ1
Qiao, JM1
Pawar, V1
Srivastava, R1
Rutten, K1
Schiene, K1
Robens, A1
Leipelt, A1
Pasqualon, T1
Read, SJ1
Christoph, T1
Thaler, HW1
Pienaar, S1
Wirnsberger, G1
Roller-Wirnsberger, RE1
Caimmi, SM1
Manca, E1
Caimmi, D1
Marseglia, GL1
Demoly, P1
Basaran, KE1
Villongco, M1
Ho, B1
Ellis, E1
Zarndt, R1
Antonova, J1
Hopkins, SR1
Powell, FL1
Kong, X1
Luo, S1
Wu, JR1
Wu, S1
De Cecco, CN1
Schoepf, UJ1
Spandorfer, AJ1
Wang, CY1
Tian, Y1
Chen, HJ1
Lu, GM1
Yang, GF1
Zhang, LJ1
Sheehan, M1
Huddleston, H1
Mousdicas, N1
Liu, X1
He, L1
Stensaas, L1
Dinger, B1
Fidone, S1
Scher, AI1
Lipton, RB1
Stewart, WF1
Bigal, M1
Konrad, B1
Prate, K1
Brannasch, K1
Ettrich, U1
Chávez, E1
Castro-Sánchez, L1
Shibayama, M1
Tsutsumi, V1
Pérez Salazar, E1
Moreno, MG1
Muriel, P1
Böhme, K1
Heckes, B1
Thomitzek, K1
Doherty, M1
Hawkey, C1
Goulder, M1
Gibb, I1
Hill, N1
Aspley, S1
Reader, S1
Erdeve, O1
Yurttutan, S1
Altug, N1
Ozdemir, R1
Gokmen, T1
Dilmen, U1
Oguz, SS1
Uras, N1
Del Rio, R1
Moya, EA1
Parga, MJ1
Madrid, C1
Iturriaga, R1
Lam, SY1
Liu, Y1
Ng, KM1
Lau, CF1
Liong, EC1
Tipoe, GL1
Fung, ML1
Adrouche-Amrani, L1
Green, RS1
Gluck, KM1
Lin, J1
Obel, G1
Krogdahl, A1
Thygesen, T1
Godballe, C1
Banerjee, M1
Tripathi, LM1
Srivastava, VM1
Puri, A1
Shukla, R1
Inoue, Y1
Isobe, M1
Shiohara, T1
Hayashi, H1
Fransen, M1
Millecamps, M1
Etienne, M1
Jourdan, D1
Eschalier, A1
Ardid, D1
Motilva, V2
Alarcón de la Lastra, C1
Bruseghini, L2
Manuel Herrerias, J1
Sánchez-Fidalgo, S2
Martín-Lacave, I1
Illanes, M1
Esteras, A1
Hämäläinen, M1
Cross, PL1
Ashby, D3
Harding, G2
Hennessy, EM1
Letley, L3
Parsons, S3
Spencer, AE1
Underwood, M3
Lee, CB1
Ha, US1
Lee, SJ1
Kim, SW1
Cho, YH1
Ettlin, DA1
Ettlin, A1
Bless, K1
Puhan, M1
Bernasconi, C1
Tillmann, HC1
Palla, S1
Gallo, LM1
Bates, KA1
Martins, RN1
Harvey, AR1
Sprott, H1
Gay, RE1
Michel, BA1
Gay, S1
Verhagen, AP1
Damen, L1
Berger, MY1
Passchier, J1
Merlijn, V1
Koes, BW1
D'Arcy, Y1
Bendtsen, L1
Buchgreitz, L1
Ashina, S1
Jensen, R1
Sibbald, RG1
Coutts, P1
Fierheller, M1
Woo, K1
Dubbel, G1
Zernikow, B1
Cross, P2
Hennessy, E2
Martin, J2
Mt-Isa, S2
Vickers, M2
Whyte, K2
Carnes, D1
Castelnuovo, E1
Spencer, A1
Ciabattoni, G2
Cinotti, GA2
Pierucci, A2
Simonetti, BM2
Manzi, M1
Pugliese, F1
Barsotti, P1
Pecci, G1
Taggi, F1
Patrono, C2
Alessandrini, A1
Gemini, R1
Chyatte, D1
Rusch, N1
Sundt, TM1
Kimoto, N1
Fujimura, A1
Yoshizawa, S1
Yoshida, K1
Murata, T1
Arakawa, K1
Kogawara, S1
Naito, S1
Nasonova, VA1
Murav'ev, IuV1
Nasonov, EL1
Lebedeva, VV1
Tsvetkova, ES1
Chichasova, NV1
Badokin, VV1
Lesniak, OM1
Demin, AA1
Baranova, EIa1
Taiyeb Ali, TB1
Waite, IM1
Winckelmann, G1
Nagel, HG1
Maier, R1
Reuther, G1
Elliott, MJ1
Woo, P1
Charles, P1
Long-Fox, A1
Woody, JN1
Maini, RN1
Sheather-Reid, RB1
Cohen, M1
Mofenson, HC1
McFee, R1
Caraccio, T1
Greensher, J1
Nikles, CJ1
Glasziou, PP1
Del Mar, CB1
Duggan, CM1
Clavarino, A1
Yelland, MJ1
Palangio, M1
Damask, MJ1
Morris, E1
Doyle, RT1
Jiang, JG1
Landau, CJ1
de Padova, A1
Menke, ER1
Jackson, CR1
Bagby, MD1
Tracy, TS1
Strain, WD1
Lye, M1
Krasnova, KN1
Chenchikova, EP1
Shkarenkova, LV1
Zipser, RD1
Hoefs, JC1
Speckart, PF1
Zia, PK1
Horton, R1
Mukhin, NA1
Poliantseva, LR1
Dziuba, MT1
Kutyrina, IM1
Tareeva, IE1
Dales, RE1
Lunau, MA1
Tierney, MG1
Schweitzer, I1
Ragni, MV1
Miller, BJ1
Whalen, R1
Ptachcinski, R1
Thilmann, AF1
Möbius, E1
Thilmann, RR1
Töpper, R1
Bradley, JD1
Brandt, KD1
Katz, BP1
Kalasinski, LA1
Ryan, SI1
Bissett, DL1
Chatterjee, R1
Hannon, DP1
Porkodi, R1
Subramaniam, R1
Krishnamurthy, V1
Madhavan, R1
Parthiban, M1
Chandrasekaran, AN1
Doutre, MS1
Beylot, C1
Konstan, MW1
Vargo, KM1
Davis, PB1
Giebink, GS1
Batalden, PB1
Le, CT1
Lassman, FM1
Buran, DJ1
Seltz, AE1
Stambaugh, JE1
Drew, J1
Finiguerra, M1
Conti, P1
Morandini, G1
Remuzzi, G1
Gotti, E1
Bombardieri, S1
Di Munno, O1
Tartarelli, G1

Clinical Trials (14)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label, Randomized, 3-way Crossover Study to Evaluate the Pharmacokinetics of Investigational Product Ibuprofen Modified-Release Tablets 800 mg Compared to Ibuprofen Tablets 800 mg in Healthy Volunteers[NCT05329454]Phase 130 participants (Actual)Interventional2020-12-24Completed
Impact of Early Targeted Ibuprofene Treatment of Patent Ductus Arteriosus (PDA) on Long Term Neurodevelopmental Outcome in Very Premature Infants (TRIOCAPI)[NCT01630278]Phase 3363 participants (Actual)Interventional2012-03-31Completed
Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus in Premature Infants: A Pilot Study[NCT03103022]Phase 120 participants (Actual)Interventional2017-06-12Completed
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253]Phase 344 participants (Anticipated)Interventional2016-03-31Completed
A Multicentre Randomised Placebo-Controlled Trail of Ibuprofen for the Prevention of Ectopic Bone-Related Pain and Disability After Elective Hip Replacement Surgery (HIPAID)[NCT00145730]Phase 41,000 participants Interventional2002-02-28Completed
Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815]51 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294]52 participants (Actual)Interventional2015-07-31Completed
Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721]Phase 2/Phase 350 participants (Actual)Interventional2015-07-31Completed
The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290]40 participants (Anticipated)Interventional2023-05-31Not yet recruiting
Acute Kidney Injury and Nonsteroidal Anti-inflammatory Drugs in Patients Undergoing High-risk Abdominal or Thoracic Surgery[NCT02553174]50 participants (Actual)Observational2016-06-01Terminated (stopped due to unable to recruit sufficient patients to satisfy study protocols)
Study of Bleeding Tendency, Platelet Function, and Pharmacokinetics of Azidothymidine (AZT) and Motrin (Ibuprofen) in HIV-Infected Hemophiliacs[NCT00002276]0 participants InterventionalCompleted
Efficacy of Intra-Articular Injection of Etanercept for Moderate and Severe Knee Osteoarthritis[NCT02722772]60 participants (Anticipated)Interventional2016-02-29Recruiting
Efficacy of Subcutaneous Injection of Etanercept for Moderate and Severe Knee Osteoarthritis[NCT02722811]60 participants (Anticipated)Interventional2016-02-29Recruiting
A Prospective, Randomized, Double-blind Study Assessing the Efficacy of Intravenous (IV) Ibuprofen Versus IV Acetaminophen for the Treatment of Pain Following Orthopaedic Low Extremity Surgery[NCT03771755]62 participants (Actual)Interventional2017-07-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for ibuprofen and Chronic Disease

ArticleYear
Efficacy and Safety of NSAIDs in Infants: A Comprehensive Review of the Literature of the Past 20 Years.
    Paediatric drugs, 2022, Volume: 24, Issue:6

    Topics: Adolescent; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; C

2022
Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review.
    Advances in therapy, 2020, Volume: 37, Issue:1

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-Response R

2020
Chronic recurrent multifocal osteomyelitis with myositis: A case report and review of the literature.
    Pediatrics international : official journal of the Japan Pediatric Society, 2020, Volume: 62, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bone Density Conservation Agents; Child; Chronic Disease; C

2020
Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants.
    The Cochrane database of systematic reviews, 2020, 12-10, Volume: 12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cause of Death; Cerebral Intraventricular Hemorrhage; Chron

2020
Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.
    The Cochrane database of systematic reviews, 2017, 08-02, Volume: 8

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Arthritis, Rheumatoid; Asp

2017
Bilateral leg edema in an older woman.
    Zeitschrift fur Gerontologie und Geriatrie, 2015, Volume: 48, Issue:1

    Topics: Aged, 80 and over; Chronic Disease; Diagnosis, Differential; Edema; Female; Heart Diseases; Humans;

2015
[Physiotherapy in patients with chronic pain].
    MMW Fortschritte der Medizin, 2010, Jan-14, Volume: 152, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Back Pain; Chronic Disease; Combined Modality Therapy; Exercise Movement T

2010
Juvenile mandibular chronic osteomyelitis: 3 cases and a literature review.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2013, Volume: 71, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Child; Chronic Disease; Delayed Diagnosis; D

2013
[Diagnosis and care of repeating headache in children].
    Duodecim; laaketieteellinen aikakauskirja, 2005, Volume: 121, Issue:6

    Topics: Acetaminophen; Age Factors; Child; Child, Preschool; Chronic Disease; Female; Finland; Headache; Hum

2005
Is any one analgesic superior for episodic tension-type headache?
    The Journal of family practice, 2006, Volume: 55, Issue:12

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Dos

2006
[The Schnitzler syndrome as a cause of recurrent fever of unknown origin].
    Deutsche medizinische Wochenschrift (1946), 1996, Jul-05, Volume: 121, Issue:27

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Chronic Disease; Female; Fever of Unknown Origi

1996

Trials

28 trials available for ibuprofen and Chronic Disease

ArticleYear
The efficacy and tolerability of pollen extract in combination with hyaluronic acid and vitamins in the management of patients affected by chronic prostatitis/chronic pelvic pain syndrome: a 26 weeks, randomized, controlled, single-blinded, phase III stud
    Minerva urology and nephrology, 2022, Volume: 74, Issue:6

    Topics: Adult; Chronic Disease; Humans; Hyaluronic Acid; Ibuprofen; Male; Pelvic Pain; Plant Extracts; Polle

2022
Development of coverage and its evaluation in the treatment of chronic wounds.
    Investigacion y educacion en enfermeria, 2017, Volume: 35, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Bandages; Cellulose; Chronic Disease; Diab

2017
Ibuprofen Blunts Ventilatory Acclimatization to Sustained Hypoxia in Humans.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Acclimatization; Adolescent; Adult; Altitude; Anti-Inflammatory Agents, Non-Steroidal; Carotid Body;

2016
[Application of a seven-day buprenorphine transdermal patch in multimorbid patients on long-term ibuprofen or diclofenac].
    MMW Fortschritte der Medizin, 2011, Jan-13, Volume: 152 Suppl 4

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Anti-Inflammatory Agents, No

2011
A randomised controlled trial of ibuprofen, paracetamol or a combination tablet of ibuprofen/paracetamol in community-derived people with knee pain.
    Annals of the rheumatic diseases, 2011, Volume: 70, Issue:9

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Chronic Disease; Dose-Respo

2011
Oral versus intravenous ibuprofen for patent ductus arteriosus closure: a randomised controlled trial in extremely low birthweight infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2012, Volume: 97, Issue:4

    Topics: Administration, Oral; Birth Weight; Chronic Disease; Cyclooxygenase Inhibitors; Ductus Arteriosus, P

2012
TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052].
    BMC musculoskeletal disorders, 2005, Nov-07, Volume: 6

    Topics: Administration, Oral; Administration, Topical; Analgesics, Non-Narcotic; Chronic Disease; Cost-Benef

2005
Preliminary experience with a terpene mixture versus ibuprofen for treatment of category III chronic prostatitis/chronic pelvic pain syndrome.
    World journal of urology, 2006, Volume: 24, Issue:1

    Topics: Adult; Chi-Square Distribution; Chronic Disease; Dose-Response Relationship, Drug; Drug Administrati

2006
Ibuprofen arginine for pain control during scaling and root planing: a randomized, triple-blind trial.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:5

    Topics: Adult; Aged; Analgesics, Non-Narcotic; Arginine; Chronic Disease; Dental Scaling; Double-Blind Metho

2006
Influence of ibuprofen-arginine on serum levels of nitric oxide metabolites in patients with chronic low back pain--a single-blind, placebo controlled pilot trial (ISRCTN18723747).
    The Journal of rheumatology, 2006, Volume: 33, Issue:12

    Topics: Analgesics; Arginine; Chronic Disease; Drug Combinations; Female; Humans; Ibuprofen; Low Back Pain;

2006
Combination of low-dose mirtazapine and ibuprofen for prophylaxis of chronic tension-type headache.
    European journal of neurology, 2007, Volume: 14, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-

2007
A pilot (real-life) randomised clinical evaluation of a pain-relieving foam dressing: (ibuprofen-foam versus local best practice).
    International wound journal, 2007, Volume: 4 Suppl 1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Bandages; Chronic

2007
Advice to use topical or oral ibuprofen for chronic knee pain in older people: randomised controlled trial and patient preference study.
    BMJ (Clinical research ed.), 2008, Jan-19, Volume: 336, Issue:7636

    Topics: Administration, Oral; Administration, Topical; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Age

2008
Topical or oral ibuprofen for chronic knee pain in older people. The TOIB study.
    Health technology assessment (Winchester, England), 2008, Volume: 12, Issue:22

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Counseling; Family Practice; Female;

2008
Effects of sulindac and ibuprofen in patients with chronic glomerular disease. Evidence for the dependence of renal function on prostacyclin.
    The New England journal of medicine, 1984, Feb-02, Volume: 310, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Aged; Chronic Disease; Creatinine; Dinoprostone; Ep

1984
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone].
    La Clinica terapeutica, 1980, Jul-31, Volume: 94, Issue:2

    Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; I

1980
[A multicenter evaluation of efficacy and tolerance in the local treatment with dolgit cream of patients with osteoarthrosis].
    Terapevticheskii arkhiv, 1995, Volume: 67, Issue:6

    Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Drug

1995
The effect of systemic ibuprofen on gingival inflammation in humans.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:10

    Topics: Adult; Chronic Disease; Dental Prophylaxis; Female; Gingivitis; Humans; Ibuprofen; Male; Periodontit

1993
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Efficacy of analgesics in chronic pain: a series of N-of-1 studies.
    Journal of pain and symptom management, 1998, Volume: 15, Issue:4

    Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Codeine; Female

1998
Preliminary experiences with a single-patient trials service in general practice.
    The Medical journal of Australia, 2000, Jul-17, Volume: 173, Issue:2

    Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N

2000
Combination hydrocodone and ibuprofen versus combination codeine and acetaminophen for the treatment of chronic pain.
    Clinical therapeutics, 2000, Volume: 22, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics; Chronic Disease; Codeine; Double-Blind Method; Drug Therapy,

2000
The effectiveness of prophylactic etodolac on postendodontic pain.
    Journal of endodontics, 2000, Volume: 26, Issue:12

    Topics: Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammato

2000
[Brufen treatment of rheumatoid arthritis in children].
    Voprosy okhrany materinstva i detstva, 1979, Volume: 24, Issue:5

    Topics: Adolescent; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic;

1979
Chronic cough responsive to ibuprofen.
    Pharmacotherapy, 1992, Volume: 12, Issue:4

    Topics: Chronic Disease; Cough; Double-Blind Method; Female; Humans; Ibuprofen; Middle Aged

1992
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee.
    The New England journal of medicine, 1991, Jul-11, Volume: 325, Issue:2

    Topics: Acetaminophen; Chronic Disease; Double-Blind Method; Female; Humans; Ibuprofen; Knee Joint; Locomoti

1991
A controlled trial comparing three treatments for chronic otitis media with effusion.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:1

    Topics: Analysis of Variance; Child; Child, Preschool; Chronic Disease; Follow-Up Studies; Hearing Loss; Hum

1990
The combination of ibuprofen and oxycodone/acetaminophen in the management of chronic cancer pain.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:6

    Topics: Acetaminophen; Adult; Aged; Analysis of Variance; Bone Neoplasms; Chronic Disease; Codeine; Double-B

1988
[Action of methoxybutropate in chronic bronchitis. Comparison with guacetisal].
    La Clinica terapeutica, 1987, Aug-31, Volume: 122, Issue:4

    Topics: Adult; Aged; Aspirin; Bronchitis; Chronic Disease; Clinical Trials as Topic; Expectorants; Female; G

1987

Other Studies

40 other studies available for ibuprofen and Chronic Disease

ArticleYear
2-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chronic Disease; Cyclooxygenase Inhib

2008
Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study.
    The Annals of otology, rhinology, and laryngology, 2020, Volume: 129, Issue:7

    Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Cohort St

2020
Familial thrombocytopenia flare-up following the first dose of mRNA-1273 Covid-19 vaccine.
    American journal of hematology, 2021, 05-01, Volume: 96, Issue:5

    Topics: 2019-nCoV Vaccine mRNA-1273; Adult; Analgesics, Non-Narcotic; Chronic Disease; COVID-19; COVID-19 Va

2021
Decreased alertness due to sleep loss increases pain sensitivity in mice.
    Nature medicine, 2017, Volume: 23, Issue:6

    Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Diseas

2017
A retrospective study of acupuncture as an adjunctive therapy to topical ibuprofen for chronic knee pain due to osteoarthritis.
    Medicine, 2019, Volume: 98, Issue:17

    Topics: Acupuncture Therapy; Administration, Cutaneous; Aged; Aged, 80 and over; Chronic Disease; Combined M

2019
Chitosan-polycaprolactone blend sponges for management of chronic osteomyelitis: A preliminary characterization and in vitro evaluation.
    International journal of pharmaceutics, 2019, Sep-10, Volume: 568

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Biocompatible Materials; Ce

2019
Burrowing as a non-reflex behavioural readout for analgesic action in a rat model of sub-chronic knee joint inflammation.
    European journal of pain (London, England), 2014, Volume: 18, Issue:2

    Topics: Analgesia; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Chronic D

2014
NSAID hypersensitivity in twins.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2014, Volume: 25, Issue:8

    Topics: Adolescent; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Autoantibodies; Celecoxib; Child; Ch

2014
(18)F-DPA-714 PET Imaging for Detecting Neuroinflammation in Rats with Chronic Hepatic Encephalopathy.
    Theranostics, 2016, Volume: 6, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrier Proteins; Chronic Disease; Disease Models,

2016
Picture of the month. Chronic bullous dermatosis of childhood.
    Archives of pediatrics & adolescent medicine, 2008, Volume: 162, Issue:6

    Topics: Anti-Inflammatory Agents; Child; Chronic Disease; Dapsone; Diagnosis, Differential; Female; Humans;

2008
Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 296, Issue:2

    Topics: Adaptation, Physiological; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carotid Body; Chronic D

2009
Patterns of medication use by chronic and episodic headache sufferers in the general population: results from the frequent headache epidemiology study.
    Cephalalgia : an international journal of headache, 2010, Volume: 30, Issue:3

    Topics: Adolescent; Adult; Aged; Analgesics; Aspirin; Caffeine; Chronic Disease; Disease Progression; Female

2010
Effects of acetyl salycilic acid and ibuprofen in chronic liver damage induced by CCl4.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:1

    Topics: Animals; Aspirin; Blotting, Western; Carbon Tetrachloride; Cell Nucleus; Chronic Disease; Collagen;

2012
Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia.
    The European respiratory journal, 2012, Volume: 39, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiovascular System; Carotid Bod

2012
Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways.
    Histochemistry and cell biology, 2012, Volume: 137, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Calcium; Carotid Artery,

2012
Failure of a repeat course of cyclooxygenase inhibitor to close a PDA is a risk factor for developing chronic lung disease in ELBW infants.
    BMC pediatrics, 2012, Jan-27, Volume: 12

    Topics: Chronic Disease; Cyclooxygenase Inhibitors; Drug Administration Schedule; Ductus Arteriosus, Patent;

2012
Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat.
    Immunopharmacology and immunotoxicology, 2003, Volume: 25, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; C-Reactive Protein; Chron

2003
Inhibitory activity of CX-659S, a novel diaminouracil derivative, against the rebound phenomenon following withdrawal of corticosteroid therapy for chronic contact hypersensitivity responses.
    International archives of allergy and immunology, 2003, Volume: 131, Issue:2

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disease; Dermatitis, Atopic; Der

2003
Preventing chronic ectopic bone-related pain and disability after hip replacement surgery with perioperative ibuprofen. A multicenter, randomized, double-blind, placebo-controlled trial (HIPAID).
    Controlled clinical trials, 2004, Volume: 25, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Australia; Chemotherapy, Ad

2004
Decrease in non-selective, non-sustained attention induced by a chronic visceral inflammatory state as a new pain evaluation in rats.
    Pain, 2004, Volume: 109, Issue:3

    Topics: Acetaminophen; Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Attention; Behavior, Animal;

2004
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
    International immunopharmacology, 2005, Volume: 5, Issue:2

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge

2005
Administration of L-arginine reduces the delay of the healing process caused by ibuprofen. Implication of COX and growth factors expression.
    Histology and histopathology, 2005, Volume: 20, Issue:2

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclooxyge

2005
Oxidative stress in a rat model of chronic gliosis.
    Neurobiology of aging, 2007, Volume: 28, Issue:7

    Topics: Acetylcysteine; Aldehydes; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Astro

2007
New pain management options: drugs.
    Nursing, 2007, Volume: 37, Issue:1

    Topics: Analgesics, Opioid; Cannabidiol; Cannabinoids; Carbazoles; Chronic Disease; Dronabinol; Drug Combina

2007
[Ambulatory pain management for children in the family practice].
    MMW Fortschritte der Medizin, 2007, Jul-19, Volume: 149, Issue:29-30

    Topics: Acetaminophen; Acute Disease; Ambulatory Care; Analgesics; Analgesics, Opioid; Child; Chronic Diseas

2007
Prevention of chronic experimental cerebral vasospasm with ibuprofen and high-dose methylprednisolone.
    Journal of neurosurgery, 1983, Volume: 59, Issue:6

    Topics: Animals; Chronic Disease; Disease Models, Animal; Dogs; Ibuprofen; Ischemic Attack, Transient; Methy

1983
[Interstitial nephritis caused by non-steroidal anti-inflammatory agents--report of 2 cases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1995, Apr-10, Volume: 84, Issue:4

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Fe

1995
Nephrotoxicity of non-steroidal anti-inflammatory drugs.
    Lancet (London, England), 1994, Aug-20, Volume: 344, Issue:8921

    Topics: Acute Kidney Injury; Adult; Biopsy; Chronic Disease; Female; Humans; Ibuprofen; Kidney; Nephritis, I

1994
Suppression of fever and the acute-phase response in a patient with juvenile chronic arthritis treated with monoclonal antibody to tumour necrosis factor-alpha (cA2).
    British journal of rheumatology, 1997, Volume: 36, Issue:5

    Topics: Acute-Phase Reaction; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; A

1997
Combined antipyretic therapy: another potential source of chronic acetaminophen toxicity.
    The Journal of pediatrics, 1998, Volume: 133, Issue:5

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Chronic Disease; Drug Interactions; Drug Therapy, Co

1998
Chronic pain, bereavement and overdose in a depressed elderly woman.
    Age and ageing, 2002, Volume: 31, Issue:3

    Topics: Acetaminophen; Aged; Aged, 80 and over; Aging; Aortic Aneurysm, Thoracic; Aspirin; Back Pain; Bereav

2002
Prostaglandins: modulators of renal function and pressor resistance in chronic liver disease.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 48, Issue:6

    Topics: Adult; Aldosterone; Ascites; Chronic Disease; Creatinine; Female; Humans; Ibuprofen; Indomethacin; K

1979
[Brufen in the treatment of chronic nephritis].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Aged; Chronic Disease; Drug Evaluation; Female; Humans; Ibuprofen; Male; Middle A

1978
Bleeding tendency, platelet function, and pharmacokinetics of ibuprofen and zidovudine in HIV(+) hemophilic men.
    American journal of hematology, 1992, Volume: 40, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Bleeding Time; Blood Platelets; Chronic Disease; Drug Therapy, Com

1992
[Recurrent aseptic meningitis (Mollaret meningitis)--spontaneous and drug-induced origin].
    Fortschritte der Neurologie-Psychiatrie, 1991, Volume: 59, Issue:12

    Topics: Aged; Chronic Disease; Diagnosis, Differential; Female; Humans; Ibuprofen; Male; Meningitis, Aseptic

1991
Photoprotective effect of topical anti-inflammatory agents against ultraviolet radiation-induced chronic skin damage in the hairless mouse.
    Photodermatology, photoimmunology & photomedicine, 1990, Volume: 7, Issue:4

    Topics: Administration, Cutaneous; Administration, Topical; Animals; Anti-Inflammatory Agents; Chronic Disea

1990
Pattern of rheumatic diseases in south India. IV. Clinical profile of juvenile rheumatoid arthritis.
    The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:10

    Topics: Arthritis, Juvenile; Aspirin; Child; Chronic Disease; Female; Humans; Ibuprofen; India; Indomethacin

1990
Chronic urticaria and monoclonal IgM: treatment with ibuprofen.
    Journal of the American Academy of Dermatology, 1990, Volume: 22, Issue:1

    Topics: Chronic Disease; Female; Humans; Ibuprofen; Immunoglobulin kappa-Chains; Immunoglobulin M; Middle Ag

1990
Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis.
    The American review of respiratory disease, 1990, Volume: 141, Issue:1

    Topics: Animals; Body Weight; Chronic Disease; Cystic Fibrosis; Dinoprostone; Humans; Ibuprofen; Leukotriene

1990
Functional significance of renal prostacyclin and thromboxane A2 production in patients with systemic lupus erythematosus.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Platelets; Chronic Disease; Dinoprost; Dinoprostone; Epoprostenol; Fe

1985