ibuprofen has been researched along with Cerebral Palsy in 4 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Cerebral Palsy: A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effects of early echocardiography-targeted ibuprofen treatment of large patent ductus arteriosus (PDA) on survival without cerebral palsy at 24 months of corrected age." | 9.41 | Effect of Early Targeted Treatment of Ductus Arteriosus with Ibuprofen on Survival Without Cerebral Palsy at 2 Years in Infants with Extreme Prematurity: A Randomized Clinical Trial. ( Beuchee, A; Cambonie, G; Clyman, R; Debillon, T; Durrmeyer, X; Favrais, G; Flamant, C; Gascoin, G; Le Thuaut, A; Ligi, I; Patkai, J; Rozé, JC, 2021) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 7.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| "To examine the effects of early echocardiography-targeted ibuprofen treatment of large patent ductus arteriosus (PDA) on survival without cerebral palsy at 24 months of corrected age." | 5.41 | Effect of Early Targeted Treatment of Ductus Arteriosus with Ibuprofen on Survival Without Cerebral Palsy at 2 Years in Infants with Extreme Prematurity: A Randomized Clinical Trial. ( Beuchee, A; Cambonie, G; Clyman, R; Debillon, T; Durrmeyer, X; Favrais, G; Flamant, C; Gascoin, G; Le Thuaut, A; Ligi, I; Patkai, J; Rozé, JC, 2021) |
| "A follow-up study of 99 infants with birth weight ≤ 1,500 g and gestational age ≤ 32 weeks who received either oral or intravenous ibuprofen for patent ductus arteriosus was conducted to assess at 18 to 24 months (corrected age), abnormal neurological, neurosensory, and cognitive impairment were defined as follows:neurological outcomes included moderate/severe cerebral palsy, neurosensory outcomes included bilateral hearing loss and blindness in either eye, and cognitive impairment included mental developmental index score < 70." | 5.17 | Impact of oral versus intravenous ibuprofen on neurodevelopmental outcome: a randomized controlled parallel study. ( Dilmen, U; Eras, Z; Erdeve, O; Gokmen, T; Ozyurt, BM; Saridas, B, 2013) |
| " We examined whether mother's use of paracetamol, aspirin or ibuprofen in pregnancy is associated with increased risk of cerebral palsy (CP) in the child." | 3.88 | Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child. ( Andersen, AN; Andersen, GL; Andersen, PK; Liew, Z; Martinussen, T; Olsen, J; Petersen, TG; Rebordosa, C; Strandberg-Larsen, K; Tollånes, MC; Uldall, P; Wilcox, AJ, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rozé, JC | 1 |
| Cambonie, G | 1 |
| Le Thuaut, A | 1 |
| Debillon, T | 1 |
| Ligi, I | 1 |
| Gascoin, G | 1 |
| Patkai, J | 1 |
| Beuchee, A | 1 |
| Favrais, G | 1 |
| Flamant, C | 1 |
| Durrmeyer, X | 1 |
| Clyman, R | 1 |
| Petersen, TG | 1 |
| Liew, Z | 1 |
| Andersen, AN | 1 |
| Andersen, GL | 1 |
| Andersen, PK | 1 |
| Martinussen, T | 1 |
| Olsen, J | 1 |
| Rebordosa, C | 1 |
| Tollånes, MC | 1 |
| Uldall, P | 1 |
| Wilcox, AJ | 1 |
| Strandberg-Larsen, K | 1 |
| Eras, Z | 1 |
| Gokmen, T | 1 |
| Erdeve, O | 1 |
| Ozyurt, BM | 1 |
| Saridas, B | 1 |
| Dilmen, U | 1 |
| Tubbs, RS | 1 |
| Law, C | 1 |
| Davis, D | 1 |
| Shoja, MM | 1 |
| Acakpo-Satchivi, L | 1 |
| Wellons, JC | 1 |
| Blount, JP | 1 |
| Oakes, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Long Term Follow-up of the TREOCAPA (Prophylactic TREatment Of the duCtus Arteriosus in Preterm Infants by Acetaminophen) Study (TREOCAPA-LT)[NCT06064825] | 500 participants (Anticipated) | Observational | 2023-11-30 | Not yet recruiting | |||
| Impact of Early Targeted Ibuprofene Treatment of Patent Ductus Arteriosus (PDA) on Long Term Neurodevelopmental Outcome in Very Premature Infants (TRIOCAPI)[NCT01630278] | Phase 3 | 363 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for ibuprofen and Cerebral Palsy
2 other studies available for ibuprofen and Cerebral Palsy
| Article | Year |
|---|---|
Use of paracetamol, ibuprofen or aspirin in pregnancy and risk of cerebral palsy in the child.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Aspirin; Cerebral Palsy; Cohort Studies; Female; Hum | 2018 |
Scheduled oral analgesics and the need for opiates in children following partial dorsal rhizotomy.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cerebral P | 2007 |