ibuprofen has been researched along with Cataract in 10 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation." | 9.19 | Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014) |
| "Ibuprofen and its major metabolites were incubated with catalase and fumarase, in the presence of protein-modifying biomolecules, to explore the mode of action of ibuprofen in protection against cataract." | 7.71 | Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract. ( Harding, JJ; Shyadehi, AZ, 2002) |
| "Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract." | 7.68 | Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992) |
| "There is evidence that ibuprofen and paracetamol can act as anti-cataract drugs." | 7.68 | Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract. ( Harding, JJ; Shyadehi, AZ, 1991) |
| "Results of a case-control of 423 cataract patients and 608 controls in Oxfordshire shows that the protective effect against cataract associated with consumption of aspirin-like analgesics (aspirin, paracetamol and ibuprofen family) is manifest even at low doses." | 7.67 | Protection against cataract by aspirin, paracetamol and ibuprofen. ( Egerton, M; Harding, JJ; Harding, RS, 1989) |
| "The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract." | 7.67 | Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986) |
| "Ibuprofen is an aspirin-like anti-inflammatory drug which appeared as a protective factor against cataract in an Oxford case-control study." | 5.28 | Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose. ( Harding, JJ; Roberts, KA, 1990) |
| "Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation." | 5.19 | Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014) |
| "Ibuprofen and its major metabolites were incubated with catalase and fumarase, in the presence of protein-modifying biomolecules, to explore the mode of action of ibuprofen in protection against cataract." | 3.71 | Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract. ( Harding, JJ; Shyadehi, AZ, 2002) |
| "Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract." | 3.68 | Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992) |
| "There is evidence that ibuprofen and paracetamol can act as anti-cataract drugs." | 3.68 | Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract. ( Harding, JJ; Shyadehi, AZ, 1991) |
| "Results of a case-control of 423 cataract patients and 608 controls in Oxfordshire shows that the protective effect against cataract associated with consumption of aspirin-like analgesics (aspirin, paracetamol and ibuprofen family) is manifest even at low doses." | 3.67 | Protection against cataract by aspirin, paracetamol and ibuprofen. ( Egerton, M; Harding, JJ; Harding, RS, 1989) |
| "The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract." | 3.67 | Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986) |
| "Ibuprofen is an aspirin-like anti-inflammatory drug which appeared as a protective factor against cataract in an Oxford case-control study." | 1.28 | Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose. ( Harding, JJ; Roberts, KA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Osaki, T | 1 |
| Ozaki, M | 1 |
| Takamura, N | 1 |
| Ogata, K | 1 |
| Tokunaga, J | 1 |
| Setoguchi, N | 1 |
| Arimori, K | 1 |
| Stevens, A | 1 |
| Heath, MM | 1 |
| Rixon, KC | 1 |
| Harding, JJ | 8 |
| Shyadehi, AZ | 3 |
| Blakytny, R | 1 |
| Roberts, KA | 1 |
| Egerton, M | 1 |
| Harding, RS | 1 |
| van Heyningen, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acetylsalicylic Acid Administered in Patients With Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System[NCT03341117] | Phase 3 | 21 participants (Actual) | Interventional | 2014-12-02 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for ibuprofen and Cataract
| Article | Year |
|---|---|
Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.
Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Binding Sites; C | 2014 |
9 other studies available for ibuprofen and Cataract
| Article | Year |
|---|---|
The effectiveness of putative anti-cataract agents in the prevention of protein glycation.
Topics: Animals; Aspirin; Cataract; Cattle; Eye Proteins; Glycation End Products, Advanced; Glycosylation; G | 1995 |
Glycation-induced inactivation of malate dehydrogenase protection by aspirin and a lens molecular chaperone, alpha-crystallin.
Topics: Animals; Aspirin; Carbohydrates; Cataract; Crystallins; Diabetes Complications; Diabetes Mellitus; G | 1996 |
Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Catalase; Cataract; Cattle; Dos | 2002 |
Attempts to provide an insight into the anti-cataract effect of ibuprofen.
Topics: Animals; Cataract; Chromatography, Affinity; Chromatography, Gel; Crystallins; Ibuprofen; Lens, Crys | 1992 |
Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen.
Topics: Acetaminophen; Animals; Aspirin; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Female; G | 1992 |
Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract.
Topics: Acetaminophen; Animals; Cataract; Cattle; Chromatography, Affinity; Crystallins; Ibuprofen; Kinetics | 1991 |
Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose.
Topics: Animals; Cataract; Cattle; Crystallins; Cyanates; Galactose; Ibuprofen; Lens, Crystalline; Male; Rat | 1990 |
Protection against cataract by aspirin, paracetamol and ibuprofen.
Topics: Acetaminophen; Aged; Aspirin; Cataract; England; Female; Humans; Ibuprofen; Male; Middle Aged; Risk | 1989 |
Do aspirin-like analgesics protect against cataract? A case-control study.
Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F | 1986 |