Page last updated: 2024-10-28

ibuprofen and Cataract

ibuprofen has been researched along with Cataract in 10 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation."9.19Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014)
"Ibuprofen and its major metabolites were incubated with catalase and fumarase, in the presence of protein-modifying biomolecules, to explore the mode of action of ibuprofen in protection against cataract."7.71Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract. ( Harding, JJ; Shyadehi, AZ, 2002)
"Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract."7.68Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992)
"There is evidence that ibuprofen and paracetamol can act as anti-cataract drugs."7.68Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract. ( Harding, JJ; Shyadehi, AZ, 1991)
"Results of a case-control of 423 cataract patients and 608 controls in Oxfordshire shows that the protective effect against cataract associated with consumption of aspirin-like analgesics (aspirin, paracetamol and ibuprofen family) is manifest even at low doses."7.67Protection against cataract by aspirin, paracetamol and ibuprofen. ( Egerton, M; Harding, JJ; Harding, RS, 1989)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."7.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"Ibuprofen is an aspirin-like anti-inflammatory drug which appeared as a protective factor against cataract in an Oxford case-control study."5.28Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose. ( Harding, JJ; Roberts, KA, 1990)
"Diclofenac instillation has been used widely in cataract surgery to prevent postoperative inflammation."5.19Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac. ( Arimori, K; Ogata, K; Osaki, T; Ozaki, M; Setoguchi, N; Takamura, N; Tokunaga, J, 2014)
"Ibuprofen and its major metabolites were incubated with catalase and fumarase, in the presence of protein-modifying biomolecules, to explore the mode of action of ibuprofen in protection against cataract."3.71Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract. ( Harding, JJ; Shyadehi, AZ, 2002)
"Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract."3.68Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992)
"There is evidence that ibuprofen and paracetamol can act as anti-cataract drugs."3.68Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract. ( Harding, JJ; Shyadehi, AZ, 1991)
"Results of a case-control of 423 cataract patients and 608 controls in Oxfordshire shows that the protective effect against cataract associated with consumption of aspirin-like analgesics (aspirin, paracetamol and ibuprofen family) is manifest even at low doses."3.67Protection against cataract by aspirin, paracetamol and ibuprofen. ( Egerton, M; Harding, JJ; Harding, RS, 1989)
"The results of a case-control study of 300 cataract patients and 609 controls indicate that long-term use of aspirin-like analgesics halves the risk of cataract."3.67Do aspirin-like analgesics protect against cataract? A case-control study. ( Harding, JJ; van Heyningen, R, 1986)
"Ibuprofen is an aspirin-like anti-inflammatory drug which appeared as a protective factor against cataract in an Oxford case-control study."1.28Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose. ( Harding, JJ; Roberts, KA, 1990)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's6 (60.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Osaki, T1
Ozaki, M1
Takamura, N1
Ogata, K1
Tokunaga, J1
Setoguchi, N1
Arimori, K1
Stevens, A1
Heath, MM1
Rixon, KC1
Harding, JJ8
Shyadehi, AZ3
Blakytny, R1
Roberts, KA1
Egerton, M1
Harding, RS1
van Heyningen, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acetylsalicylic Acid Administered in Patients With Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System[NCT03341117]Phase 321 participants (Actual)Interventional2014-12-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for ibuprofen and Cataract

ArticleYear
Albumin-binding of diclofenac and the effect of a site II inhibitor in the aqueous humor of cataract patients with the instillation of diclofenac.
    Biopharmaceutics & drug disposition, 2014, Volume: 35, Issue:4

    Topics: Administration, Ophthalmic; Anti-Inflammatory Agents, Non-Steroidal; Aqueous Humor; Binding Sites; C

2014

Other Studies

9 other studies available for ibuprofen and Cataract

ArticleYear
The effectiveness of putative anti-cataract agents in the prevention of protein glycation.
    Journal of the American Optometric Association, 1995, Volume: 66, Issue:12

    Topics: Animals; Aspirin; Cataract; Cattle; Eye Proteins; Glycation End Products, Advanced; Glycosylation; G

1995
Glycation-induced inactivation of malate dehydrogenase protection by aspirin and a lens molecular chaperone, alpha-crystallin.
    Biochimica et biophysica acta, 1996, Apr-12, Volume: 1315, Issue:3

    Topics: Animals; Aspirin; Carbohydrates; Cataract; Crystallins; Diabetes Complications; Diabetes Mellitus; G

1996
Protective effects of ibuprofen and its major metabolites against in vitro inactivation of catalase and fumarase: relevance to cataract.
    Biochimica et biophysica acta, 2002, May-21, Volume: 1587, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Catalase; Cataract; Cattle; Dos

2002
Attempts to provide an insight into the anti-cataract effect of ibuprofen.
    Biochemical Society transactions, 1992, Volume: 20, Issue:2

    Topics: Animals; Cataract; Chromatography, Affinity; Chromatography, Gel; Crystallins; Ibuprofen; Lens, Crys

1992
Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen.
    Experimental eye research, 1992, Volume: 54, Issue:4

    Topics: Acetaminophen; Animals; Aspirin; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Female; G

1992
Investigations of ibuprofen and paracetamol binding to lens proteins to explore their protective role against cataract.
    Biochemical pharmacology, 1991, Nov-06, Volume: 42, Issue:11

    Topics: Acetaminophen; Animals; Cataract; Cattle; Chromatography, Affinity; Crystallins; Ibuprofen; Kinetics

1991
Ibuprofen, a putative anti-cataract drug, protects the lens against cyanate and galactose.
    Experimental eye research, 1990, Volume: 50, Issue:2

    Topics: Animals; Cataract; Cattle; Crystallins; Cyanates; Galactose; Ibuprofen; Lens, Crystalline; Male; Rat

1990
Protection against cataract by aspirin, paracetamol and ibuprofen.
    Acta ophthalmologica, 1989, Volume: 67, Issue:5

    Topics: Acetaminophen; Aged; Aspirin; Cataract; England; Female; Humans; Ibuprofen; Male; Middle Aged; Risk

1989
Do aspirin-like analgesics protect against cataract? A case-control study.
    Lancet (London, England), 1986, May-17, Volume: 1, Issue:8490

    Topics: Acetaminophen; Aged; Analgesics; Aspirin; Cataract; Diabetes Complications; Epidemiologic Methods; F

1986