Page last updated: 2024-10-28

ibuprofen and Cancer of Rectum

ibuprofen has been researched along with Cancer of Rectum in 6 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"alpha-Methylacyl-CoA racemase (AMACR), an enzyme involved in oxidation of branched chain fatty acids and cholesterol metabolites, as well as ibuprofen metabolism, is overexpressed in colorectal adenomas and cancer."5.12Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. ( Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R, 2007)
"A population-based study of 750 rectal cancer cases with interview and tumor DNA were compared to 1,205 population-based controls."1.35Tumor markers and rectal cancer: support for an inflammation-related pathway. ( Caan, BJ; Herrick, J; Samowitz, W; Slattery, ML; Wolff, RK, 2009)
"Data were available from 1,577 cases of colon cancer that were matched to 1,971 population-based controls and 794 cases of rectal cancer that were matched to 1,001 population-based controls."1.33PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). ( Curtin, K; Levin, TR; Ma, KN; Murtaugh, M; Potter, JD; Samowitz, W; Slattery, ML; Sweeney, C; Wolff, R, 2006)
"Variant CYP2C9 genotypes enhanced the protective effect of ibuprofen on the prevention of colorectal cancer, and a dose-response relationship with respect to increasing numbers of variant alleles was seen (P interaction = ."1.33Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. ( Andersen, K; Curtin, K; Levin, TR; Ma, KN; Samowitz, WS; Slattery, ML; Sweeney, C; Wolff, RK, 2006)
"Aspirin was the most prospective chemopreventive agents for colorectal polyp, colon and rectal carcinoma for its capability of reducing the risk of cardio-cerebral vascular disease as well."1.31[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma]. ( Gao, X; Li, M; Song, S; Sun, F; Sun, H; Sun, S; Zhang, W, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Slattery, ML3
Wolff, RK2
Herrick, J1
Caan, BJ1
Samowitz, W2
Gao, X1
Sun, S1
Sun, F1
Li, M1
Sun, H1
Zhang, W1
Song, S1
Curtin, K2
Wolff, R1
Ma, KN2
Sweeney, C2
Murtaugh, M1
Potter, JD1
Levin, TR2
Samowitz, WS1
Andersen, K1
Daugherty, SE1
Platz, EA1
Shugart, YY1
Fallin, MD1
Isaacs, WB1
Chatterjee, N1
Welch, R1
Huang, WY1
Hayes, RB1
Chow, HH1
Earnest, DL1
Clark, D1
Mason-Liddil, N1
Kramer, CB1
Einspahr, JG1
Guillen-Rodriguez, JM1
Roe, DJ1
Malone, W1
Crowell, JA1
Alberts, DS1

Trials

2 trials available for ibuprofen and Cancer of Rectum

ArticleYear
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2007, Volume: 16, Issue:8

    Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies

2007
Effect of subacute ibuprofen dosing on rectal mucosal prostaglandin E2 levels in healthy subjects with a history of resected polyps.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Chemoprevention; Dinoprostone; Dos

2000

Other Studies

4 other studies available for ibuprofen and Cancer of Rectum

ArticleYear
Tumor markers and rectal cancer: support for an inflammation-related pathway.
    International journal of cancer, 2009, Oct-01, Volume: 125, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biomarkers, Tumor; Cali

2009
[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2002, Volume: 36, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Humans; Ibupr

2002
PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).
    Cancer causes & control : CCC, 2006, Volume: 17, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; California; Case-Control Studies; Col

2006
Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:7

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Case-C

2006