ibuprofen has been researched along with Cancer of Rectum in 6 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "alpha-Methylacyl-CoA racemase (AMACR), an enzyme involved in oxidation of branched chain fatty acids and cholesterol metabolites, as well as ibuprofen metabolism, is overexpressed in colorectal adenomas and cancer." | 5.12 | Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. ( Chatterjee, N; Daugherty, SE; Fallin, MD; Hayes, RB; Huang, WY; Isaacs, WB; Platz, EA; Shugart, YY; Welch, R, 2007) |
| "A population-based study of 750 rectal cancer cases with interview and tumor DNA were compared to 1,205 population-based controls." | 1.35 | Tumor markers and rectal cancer: support for an inflammation-related pathway. ( Caan, BJ; Herrick, J; Samowitz, W; Slattery, ML; Wolff, RK, 2009) |
| "Data were available from 1,577 cases of colon cancer that were matched to 1,971 population-based controls and 794 cases of rectal cancer that were matched to 1,001 population-based controls." | 1.33 | PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States). ( Curtin, K; Levin, TR; Ma, KN; Murtaugh, M; Potter, JD; Samowitz, W; Slattery, ML; Sweeney, C; Wolff, R, 2006) |
| "Variant CYP2C9 genotypes enhanced the protective effect of ibuprofen on the prevention of colorectal cancer, and a dose-response relationship with respect to increasing numbers of variant alleles was seen (P interaction = ." | 1.33 | Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention. ( Andersen, K; Curtin, K; Levin, TR; Ma, KN; Samowitz, WS; Slattery, ML; Sweeney, C; Wolff, RK, 2006) |
| "Aspirin was the most prospective chemopreventive agents for colorectal polyp, colon and rectal carcinoma for its capability of reducing the risk of cardio-cerebral vascular disease as well." | 1.31 | [Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma]. ( Gao, X; Li, M; Song, S; Sun, F; Sun, H; Sun, S; Zhang, W, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slattery, ML | 3 |
| Wolff, RK | 2 |
| Herrick, J | 1 |
| Caan, BJ | 1 |
| Samowitz, W | 2 |
| Gao, X | 1 |
| Sun, S | 1 |
| Sun, F | 1 |
| Li, M | 1 |
| Sun, H | 1 |
| Zhang, W | 1 |
| Song, S | 1 |
| Curtin, K | 2 |
| Wolff, R | 1 |
| Ma, KN | 2 |
| Sweeney, C | 2 |
| Murtaugh, M | 1 |
| Potter, JD | 1 |
| Levin, TR | 2 |
| Samowitz, WS | 1 |
| Andersen, K | 1 |
| Daugherty, SE | 1 |
| Platz, EA | 1 |
| Shugart, YY | 1 |
| Fallin, MD | 1 |
| Isaacs, WB | 1 |
| Chatterjee, N | 1 |
| Welch, R | 1 |
| Huang, WY | 1 |
| Hayes, RB | 1 |
| Chow, HH | 1 |
| Earnest, DL | 1 |
| Clark, D | 1 |
| Mason-Liddil, N | 1 |
| Kramer, CB | 1 |
| Einspahr, JG | 1 |
| Guillen-Rodriguez, JM | 1 |
| Roe, DJ | 1 |
| Malone, W | 1 |
| Crowell, JA | 1 |
| Alberts, DS | 1 |
2 trials available for ibuprofen and Cancer of Rectum
| Article | Year |
|---|---|
Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma.
Topics: Adenoma; Aged; Alleles; Anti-Inflammatory Agents, Non-Steroidal; Aspartic Acid; Case-Control Studies | 2007 |
Effect of subacute ibuprofen dosing on rectal mucosal prostaglandin E2 levels in healthy subjects with a history of resected polyps.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Chemoprevention; Dinoprostone; Dos | 2000 |
4 other studies available for ibuprofen and Cancer of Rectum
| Article | Year |
|---|---|
Tumor markers and rectal cancer: support for an inflammation-related pathway.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Biomarkers, Tumor; Cali | 2009 |
[Nonsteroidal anti-inflammatory drugs and the risk of polyposis, colon carcinoma and rectal carcinoma].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Female; Humans; Ibupr | 2002 |
PPARgamma and colon and rectal cancer: associations with specific tumor mutations, aspirin, ibuprofen and insulin-related genes (United States).
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; California; Case-Control Studies; Col | 2006 |
Interactions between CYP2C9 and UGT1A6 polymorphisms and nonsteroidal anti-inflammatory drugs in colorectal cancer prevention.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Aspirin; Case-C | 2006 |