ibuprofen and Burns
ibuprofen has been researched along with Burns in 37 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study suggests that Ibuprofen has no preventive effect on progressive dermal ischemia after burning." | 7.71 | Failure of Ibuprofen to prevent progressive dermal ischemia after burning in guinea pigs. ( Chen, H; Lin, Z; Ma, W; Ning, G; Tan, Q; Wang, L; Zhou, X, 2002) |
| "The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns." | 7.70 | Ibuprofen modulates tissue perfusion in partial-thickness burns. ( Barrow, RE; Ramirez, RJ; Zhang, XJ, 2000) |
| "We determined the effect of topically applied ibuprofen on formation of second-degree burn edema and prostanoid production, a possible causative factor." | 7.67 | Topical ibuprofen decreases early postburn edema. ( Demling, RH; Lalonde, C, 1987) |
| "To evaluate the efficacy of ibuprofen-containing foam dressing in partial-thickness burns." | 5.69 | Pain Management With Topical Ibuprofen in Partial-Thickness Burn Wounds and Effects on Wound Healing: A Prospective Randomized Clinical Study. ( Akgun, AE; Alkin, M, 2023) |
| " Spinal pretreatment with cyclooxygenase (10 and 30 microg (S)-(+)-ibuprofen; and 3 and 30 microg ketorolac) and nitric oxide synthase (33 and 100 microg N(G) Nitro-L-arginine methyl ester hydrochloride (L-NAME) and 10 microg thiocitrulline) inhibitors resulted in no specific anti-allodynia." | 3.74 | Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase. ( Doom, CM; Maruyama, KP; Nanigian, DB; Sorkin, LS, 2008) |
| "This study suggests that Ibuprofen has no preventive effect on progressive dermal ischemia after burning." | 3.71 | Failure of Ibuprofen to prevent progressive dermal ischemia after burning in guinea pigs. ( Chen, H; Lin, Z; Ma, W; Ning, G; Tan, Q; Wang, L; Zhou, X, 2002) |
| "The anti-inflammatory and anticoagulant effects of ibuprofen and heparin may enhance skin perfusion in cutaneous scald burns." | 3.70 | Ibuprofen modulates tissue perfusion in partial-thickness burns. ( Barrow, RE; Ramirez, RJ; Zhang, XJ, 2000) |
| "A group of 15 burned children and young adults with large burns (mean, 41% +/- 15% BSA) were administered ibuprofen (40 mg/kg for 3 days)." | 3.68 | Ibuprofen lowers body temperature and metabolic rate of humans with burn injury. ( Caldwell, FT; Cone, JB; Wallace, BH, 1992) |
| "We determined the effect of topically applied ibuprofen on formation of second-degree burn edema and prostanoid production, a possible causative factor." | 3.67 | Topical ibuprofen decreases early postburn edema. ( Demling, RH; Lalonde, C, 1987) |
| "We injected Escherichia coli endotoxin, 2 micrograms/kg, beneath the eschar of sheep with 25% total body surface full-thickness burns to determine whether burn tissue in the presence of endotoxin releases prostanoids, particularly thromboxane A2, (TxA2), and if increased local TxA2 production can lead to distant lung dysfunction." | 3.67 | Endotoxin-induced prostanoid production by the burn wound can cause distant lung dysfunction. ( Demling, RH; Hechtman, H; Lalonde, CC; Wenger, H; West, K; Wong, C, 1986) |
| "Ibuprofen was found to decrease neutrophil chemiluminescence, lymphocyte blastogenesis, and helper/inducer T-lymphocyte infiltration of a sponge matrix model." | 1.29 | Effect of ibuprofen on the inflammatory response to surgical wounds. ( Dong, YL; Fleming, RY; Herndon, DN; Waymack, JP; Yan, TZ, 1993) |
| "Ibuprofen at high doses was found to significantly diminish the hypermetabolic response to burn injury and sepsis." | 1.28 | The effect of ibuprofen on postburn metabolic and immunologic function. ( Waymack, JP, 1989) |
| "Standard burns were sequentially produced on the backs of Sprague-Dawley rats at 0, 1, 2, and 2 1/2 hr, followed by the IV injection of Evans blue dye." | 1.27 | Arachidonic acid metabolites mediate early burn edema. ( Alexander, F; Hechtman, HB; Huval, WV; Lelcuk, S; Mathieson, M; Shepro, D; Teoh, KH; Valeri, CR, 1984) |
| "These alterations were not due to pulmonary edema as there was no increase in measured lung water." | 1.27 | Early lung dysfunction after major burns: role of edema and vasoactive mediators. ( Demling, RH; Hechtman, H; Jin, LJ; Lalonde, C; West, K; Wong, C, 1985) |
| " Animals were then treated with the four agents in carefully defined dosage regimens, and survival was again determined on the tenth postburn day." | 1.27 | Postburn immunosuppression in an animal model. IV. Improved resistance to septic challenge with immunomodulating drugs. ( Bartle, EJ; Bender, EM; Carter, WH; Hansbrough, JF; Mansour, MA; Zapata-Sirvent, RL, 1986) |
| "Ibuprofen pretreatment (12." | 1.27 | Lung dysfunction after thermal injury in relation to prostanoid and oxygen radical release. ( Demling, RH; Jin, LJ; Lalonde, C, 1986) |
Research
Studies (37)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (45.95) | 18.7374 |
| 1990's | 11 (29.73) | 18.2507 |
| 2000's | 4 (10.81) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 4 (10.81) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Akgun, AE | 1 |
| Alkin, M | 1 |
| Natalwala, I | 1 |
| Kiely, J | 1 |
| Kilshaw, A | 1 |
| McKay, G | 1 |
| Chu, V | 1 |
| Phipps, A | 1 |
| Anwar, MU | 1 |
| Yarwood, J | 1 |
| Sandhu, R | 1 |
| Muthayya, P | 1 |
| Sloan, B | 1 |
| Chu, H | 1 |
| Sen, S | 1 |
| Wall, SL | 2 |
| Clarke, DL | 2 |
| Nauhaus, H | 1 |
| Allorto, NL | 2 |
| Tan, Q | 1 |
| Lin, Z | 1 |
| Ma, W | 1 |
| Chen, H | 1 |
| Wang, L | 1 |
| Ning, G | 1 |
| Zhou, X | 1 |
| Jennes, S | 1 |
| Saidane, G | 1 |
| Fauville, JP | 1 |
| Ledoux, M | 1 |
| Colinet, B | 1 |
| Sorkin, LS | 1 |
| Doom, CM | 1 |
| Maruyama, KP | 1 |
| Nanigian, DB | 1 |
| Alexander, F | 1 |
| Mathieson, M | 1 |
| Teoh, KH | 1 |
| Huval, WV | 1 |
| Lelcuk, S | 1 |
| Valeri, CR | 1 |
| Shepro, D | 1 |
| Hechtman, HB | 1 |
| Hansbrough, J | 1 |
| Peterson, V | 1 |
| Zapata-Sirvent, R | 1 |
| Claman, HN | 1 |
| Ehrlich, HP | 5 |
| Dong, YL | 2 |
| Herndon, DN | 2 |
| Yan, TZ | 2 |
| Waymack, JP | 3 |
| Fleming, RY | 1 |
| Cetinkale, O | 1 |
| Demir, M | 1 |
| Sayman, HB | 1 |
| Ayan, F | 1 |
| Onsel, C | 1 |
| Petersen, KL | 1 |
| Brennum, J | 1 |
| Dahl, JB | 1 |
| Sakurai, H | 1 |
| Traber, LD | 1 |
| Traber, DL | 1 |
| Barrow, RE | 1 |
| Ramirez, RJ | 1 |
| Zhang, XJ | 1 |
| Regas, FC | 1 |
| Wallace, BH | 1 |
| Caldwell, FT | 1 |
| Cone, JB | 1 |
| Grbic, JT | 1 |
| Mannick, JA | 1 |
| Gough, DB | 1 |
| Rodrick, ML | 1 |
| Rockwell, WB | 1 |
| Demling, RH | 7 |
| LaLonde, C | 7 |
| Wong, C | 2 |
| Jin, LJ | 2 |
| Hechtman, H | 2 |
| West, K | 3 |
| Zapata-Sirvent, RL | 1 |
| Hansbrough, JF | 1 |
| Bender, EM | 1 |
| Bartle, EJ | 1 |
| Mansour, MA | 1 |
| Carter, WH | 1 |
| Bjornson, AB | 1 |
| Knippenberg, RW | 1 |
| Bjornson, HS | 1 |
| Freeman, TR | 1 |
| Shelby, J | 1 |
| Zhu, D | 1 |
| Katz, A | 1 |
| Ryan, P | 1 |
| Demling, R | 1 |
| MacGarvey, U | 1 |
| McGrane, WL | 1 |
| White, ME | 1 |
| Odessey, R | 1 |
| Wenger, H | 1 |
| Lalonde, CC | 1 |
| Iizuka, Y | 1 |
| Tanaka, K | 1 |
Reviews
1 review available for ibuprofen and Burns
| Article | Year |
|---|---|
Experimental evaluation of the analgesic effect of ibuprofen on primary and secondary hyperalgesia.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cross-Over Studies; Double-Blind | 1997 |
Trials
2 trials available for ibuprofen and Burns
| Article | Year |
|---|---|
Pain Management With Topical Ibuprofen in Partial-Thickness Burn Wounds and Effects on Wound Healing: A Prospective Randomized Clinical Study.
Topics: Burns; Cicatrix; Humans; Ibuprofen; Pain Management; Prospective Studies; Soft Tissue Injuries; Woun | 2023 |
Experimental evaluation of the analgesic effect of ibuprofen on primary and secondary hyperalgesia.
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cross-Over Studies; Double-Blind | 1997 |
Other Studies
35 other studies available for ibuprofen and Burns
| Article | Year |
|---|---|
The Pinderfields hospital pain management protocol for enzymatic debridement of burns wounds.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Ane | 2020 |
Pre-attendance analgesia advice for small acute paediatric burns in the British Isles: A National Survey.
Topics: Acetaminophen; Ambulatory Care; Analgesics; Burns; Child; Humans; Ibuprofen; Pain Management; Pain, | 2020 |
Barriers to adequate analgesia in paediatric burns patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Burns; Child; Child, Preschool; Clinica | 2020 |
Analgesia protocols for burns dressings: Challenges with implementation.
Topics: Academic Medical Centers; Acetaminophen; Analgesics; Anesthetics, Inhalation; Bandages; Burns; Child | 2019 |
Failure of Ibuprofen to prevent progressive dermal ischemia after burning in guinea pigs.
Topics: Animals; Burns; Cyclooxygenase Inhibitors; Dermis; Disease Models, Animal; Guinea Pigs; Ibuprofen; I | 2002 |
Transient selective factor X deficiency in a severely burned child.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Body Surface Area; Burns; Erythrocyt | 2008 |
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase.
Topics: Animals; Behavior, Animal; Burns; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Diltiazem; En | 2008 |
Arachidonic acid metabolites mediate early burn edema.
Topics: Animals; Body Water; Burns; Calcium Channel Blockers; Capillary Permeability; Chromones; Edema; Ibup | 1984 |
Postburn immunosuppression in an animal model. II. Restoration of cell-mediated immunity by immunomodulating drugs.
Topics: Animals; Burns; Chlorides; Cimetidine; Cyclophosphamide; Dinitrofluorobenzene; Drug Hypersensitivity | 1984 |
Anti-inflammatory drugs in the vascular response to burn injury.
Topics: Animals; Anti-Inflammatory Agents; Blood Coagulation; Burns; Epoprostenol; Hydrocortisone; Ibuprofen | 1984 |
Promotion of vascular patency in dermal burns with ibuprofen.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Vessels; Body Fluids; Burns; Fibrinolysis; Freezing; Ib | 1984 |
Blockade of prostaglandin products augments macrophage and neutrophil tumor necrosis factor synthesis in burn injury.
Topics: Animals; Burns; Ibuprofen; Lipopolysaccharides; Macrophages; Male; Neutrophils; Prostaglandins; Pros | 1993 |
Effect of ibuprofen on the inflammatory response to surgical wounds.
Topics: Animals; Burns; Cecum; Dermatologic Surgical Procedures; Ibuprofen; Immune Tolerance; Inflammation; | 1993 |
Effects of allopurinol, ibuprofen and cyclosporin A on local microcirculatory disturbance due to burn injuries.
Topics: Allopurinol; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Cyclospo | 1997 |
Altered systemic organ blood flow after combined injury with burn and smoke inhalation.
Topics: Animals; Blood Pressure; Body Temperature; Burns; Female; Heart Rate; Hematocrit; Hemodynamics; Ibup | 1998 |
Ibuprofen modulates tissue perfusion in partial-thickness burns.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Burns; Ear, | 2000 |
Elucidating the vascular response to burns with a new rat model.
Topics: Animals; Blood Vessels; Burns; Ibuprofen; Ischemia; Male; Rats; Rats, Inbred Strains; Regional Blood | 1992 |
Ibuprofen lowers body temperature and metabolic rate of humans with burn injury.
Topics: Adolescent; Basal Metabolism; Body Temperature; Burns; Calorimetry; Child; Humans; Ibuprofen; Nitrog | 1992 |
The role of prostaglandin E2 in immune suppression following injury.
Topics: Adolescent; Adult; Aged; Burns; Dinoprostone; Endotoxins; Escherichia coli; Female; Humans; Ibuprofe | 1991 |
An ibuprofen-antagonized plasmin inhibitor released by human endothelial cells.
Topics: Antifibrinolytic Agents; Burns; Cells, Cultured; Cicatrix; Endothelium; Fibrinolysis; Hot Temperatur | 1991 |
Identification and modifications of the pulmonary and systemic inflammatory and biochemical changes caused by a skin burn.
Topics: Allopurinol; Animals; Burns; Deferoxamine; Hemodynamics; Ibuprofen; Lipid Peroxidation; Liver; Lung; | 1990 |
Early postburn lipid peroxidation: effect of ibuprofen and allopurinol.
Topics: Allopurinol; Animals; Burns; Disease Models, Animal; Edema; Ibuprofen; Inflammation; Lipid Peroxidat | 1990 |
Early lung dysfunction after major burns: role of edema and vasoactive mediators.
Topics: Animals; Burns; Dextrans; Ibuprofen; Isotonic Solutions; Lung; Lung Compliance; Lymphatic System; Pu | 1985 |
The effect of ibuprofen on postburn metabolic and immunologic function.
Topics: Animals; Burns; Complement C3; Ibuprofen; Immunoglobulin G; Pseudomonas Infections; Rats; Rats, Inbr | 1989 |
Postburn immunosuppression in an animal model. IV. Improved resistance to septic challenge with immunomodulating drugs.
Topics: Animals; Anti-Infective Agents, Local; Burns; Cerium; Cimetidine; Cyclophosphamide; Dose-Response Re | 1986 |
Nonsteroidal anti-inflammatory drugs correct the bactericidal defect of polymorphonuclear leukocytes in a guinea pig model of thermal injury.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Bactericidal A | 1988 |
Effect of anti-PGE antibody on cell-mediated immune response in thermally injured mice.
Topics: Animals; Antibodies; Burns; Graft vs Host Reaction; Host vs Graft Reaction; Ibuprofen; Immunity, Cel | 1988 |
Early pulmonary and hemodynamic effects of a chest wall burn (effect of ibuprofen).
Topics: Animals; Burns; Cardiac Output; Central Venous Pressure; Fluid Therapy; Hemodynamics; Humans; Ibupro | 1988 |
Topical ibuprofen decreases thromboxane release from the endotoxin-stimulated burn wound.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Blood Pressure; Burns; Endotoxins; E | 1986 |
Ibuprofen as an antagonist of inhibitors of fibrinolysis in wound fluid.
Topics: Animals; Antifibrinolytic Agents; Burns; Extracellular Space; Fibrin; Fibrinolysis; Ibuprofen; Male; | 1987 |
Topical ibuprofen decreases early postburn edema.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Topical; Animals; Burns; Edema; Ibuprofen; Lymph; Pros | 1987 |
Lung dysfunction after thermal injury in relation to prostanoid and oxygen radical release.
Topics: Anesthesia; Animals; Burns; Free Radicals; Ibuprofen; Lung; Oxygen; Postmortem Changes; Prostaglandi | 1986 |
Effect of inhibitors of proteolysis and arachidonic acid metabolism on burn-induced protein breakdown.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Burns; Hindlimb; Ibuprofen; In Vitro Techniqu | 1985 |
Endotoxin-induced prostanoid production by the burn wound can cause distant lung dysfunction.
Topics: Animals; Burns; Endotoxins; Hemodynamics; Ibuprofen; Injections, Intravenous; Lung Diseases; Lymph; | 1986 |
][A new method for screening of analgesics applied to heat induced inflammatory pain].
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Burns; Drug Evaluation, Preclinical; Flufenamic Acid; Hab | 1974 |