Page last updated: 2024-10-28

ibuprofen and Brain Neoplasms

ibuprofen has been researched along with Brain Neoplasms in 9 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research Excerpts

ExcerptRelevanceReference
"To determine the effects of ibuprofen (Ibp) on the vessel proliferation and necrosis in a rat glioma model."9.16Effects of Ibuprofen on orthotopic glioma model in rats. ( Bilir, A; Bozkurt, ER; Dagêstan, Y; Karaca, I, 2012)
" We have studied two liposoluble drugs, MPA and the analgesic ibuprofen, on glioma vascularization in vivo."7.71Vascularization pattern of C6 glioma is modified with medroxyprogesterone acetate and ibuprofen in Wistar rat brain. ( Altinoz, MA; Altug, T; Aydiner, A; Bilir, A; Bozcali, E; Ozar, E; Sav, A; Taskin, M, 2001)
"This study compares the effect of gamma-linolenic acid (GLA) and its precursor linoleic acid (LA) on survival of 36B10 malignant rat astrocytoma cells and 'normal' rat astrocytes."7.70Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes. ( Davis, CS; McCaw, R; Robbins, ME; Spector, AA; Vartak, S, 1998)
" Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture."7.70Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000)
"The effects of long-term low- and high-dose ibuprofen on tumor growth and permeability were assessed in a glioma model in rats."7.67Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model. ( Del Maestro, RF; Farrell, CL; Megyesi, J, 1988)
"To determine the effects of ibuprofen (Ibp) on the vessel proliferation and necrosis in a rat glioma model."5.16Effects of Ibuprofen on orthotopic glioma model in rats. ( Bilir, A; Bozkurt, ER; Dagêstan, Y; Karaca, I, 2012)
" We have studied two liposoluble drugs, MPA and the analgesic ibuprofen, on glioma vascularization in vivo."3.71Vascularization pattern of C6 glioma is modified with medroxyprogesterone acetate and ibuprofen in Wistar rat brain. ( Altinoz, MA; Altug, T; Aydiner, A; Bilir, A; Bozcali, E; Ozar, E; Sav, A; Taskin, M, 2001)
"This study compares the effect of gamma-linolenic acid (GLA) and its precursor linoleic acid (LA) on survival of 36B10 malignant rat astrocytoma cells and 'normal' rat astrocytes."3.70Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes. ( Davis, CS; McCaw, R; Robbins, ME; Spector, AA; Vartak, S, 1998)
" Using cultures of rodent and human malignant glioma cell lines, we demonstrated that millimolar concentrations of acetylsalicylate, acetaminophen, and ibuprofen all significantly reduce cell numbers after several days of culture."3.70Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture. ( Casper, D; Jaggernauth, WA; LaSala, PA; Lekhraj, R; Pidel, A; Rowe, JD; Tribius, S; Werner, P; Yaparpalvi, US, 2000)
"The effects of long-term low- and high-dose ibuprofen on tumor growth and permeability were assessed in a glioma model in rats."3.67Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model. ( Del Maestro, RF; Farrell, CL; Megyesi, J, 1988)
" The authors have used the rat C6 glioma spheroid implantation model to compare the effects of two steroids (dexamethasone and methylprednisolone) and two NSAID's (ibuprofen and indomethacin) on protein extravasation caused by intracranial gliomas."3.67Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model. ( Del Maestro, RF; Farrell, CL; Reichman, HR, 1986)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Gao, X1
Guo, N1
Xu, H1
Pan, T1
Lei, H1
Yan, A1
Mi, Y1
Xu, L1
Bartels, LE1
Mattheolabakis, G1
Vaeth, BM1
LaComb, JF1
Wang, R1
Zhi, J1
Komninou, D1
Rigas, B1
Mackenzie, GG1
Bauer, DF1
Waters, AM1
Tubbs, RS1
Rozzelle, CJ1
Wellons, JC1
Blount, JP1
Oakes, WJ1
Dagêstan, Y1
Karaca, I1
Bozkurt, ER1
Bilir, A2
Vartak, S1
McCaw, R1
Davis, CS1
Robbins, ME1
Spector, AA1
Casper, D1
Lekhraj, R1
Yaparpalvi, US1
Pidel, A1
Jaggernauth, WA1
Werner, P1
Tribius, S1
Rowe, JD1
LaSala, PA1
Altinoz, MA1
Ozar, E1
Taskin, M1
Bozcali, E1
Altug, T1
Aydiner, A1
Sav, A1
Farrell, CL2
Megyesi, J1
Del Maestro, RF2
Reichman, HR1

Trials

1 trial available for ibuprofen and Brain Neoplasms

ArticleYear
Effects of Ibuprofen on orthotopic glioma model in rats.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2012, Volume: 22, Issue:11

    Topics: Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Cel

2012

Other Studies

8 other studies available for ibuprofen and Brain Neoplasms

ArticleYear
Ibuprofen induces ferroptosis of glioblastoma cells via downregulation of nuclear factor erythroid 2-related factor 2 signaling pathway.
    Anti-cancer drugs, 2020, Volume: 31, Issue:1

    Topics: Amino Acid Transport System y+; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Down-Regu

2020
The novel agent phospho-glycerol-ibuprofen-amide (MDC-330) inhibits glioblastoma growth in mice: an effect mediated by cyclin D1.
    Carcinogenesis, 2016, Volume: 37, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cyclin D1; Glioblastoma; Ibuprofen; Mice

2016
Safety and utility of scheduled nonnarcotic analgesic medications in children undergoing craniotomy for brain tumor.
    Neurosurgery, 2010, Volume: 67, Issue:2

    Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; B

2010
Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes.
    British journal of cancer, 1998, Volume: 77, Issue:10

    Topics: alpha-Linolenic Acid; Animals; Antineoplastic Agents; Antioxidants; Astrocytes; Astrocytoma; Brain N

1998
Acetaminophen selectively reduces glioma cell growth and increases radiosensitivity in culture.
    Journal of neuro-oncology, 2000, Volume: 46, Issue:3

    Topics: Acetaminophen; Adult; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Brain; Brain Neoplasms; Ce

2000
Vascularization pattern of C6 glioma is modified with medroxyprogesterone acetate and ibuprofen in Wistar rat brain.
    Pathology oncology research : POR, 2001, Volume: 7, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Neoplasms; Drug Therapy, Combination; Glioma

2001
Effect of ibuprofen on tumor growth in the C6 spheroid implantation glioma model.
    Journal of neurosurgery, 1988, Volume: 68, Issue:6

    Topics: Animals; Brain Neoplasms; Cell Division; Dose-Response Relationship, Drug; Evans Blue; Glioma; Ibupr

1988
Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model.
    Journal of neurosurgery, 1986, Volume: 65, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Capillary Perm

1986