ibuprofen has been researched along with Brain Inflammation in 15 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors." | 8.02 | The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021) |
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 5.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| "The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors." | 4.02 | The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021) |
| "In this study we examined the protective effects of icariin, a flavonol isolated from Herba epimedii, on learning and memory in a rat model with brain inflammation induced by lipopolysaccharide (LPS)." | 3.76 | Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats. ( Gong, Q; Guo, J; Li, F; Lu, Y; Shi, J; Wu, Q, 2010) |
| "Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that has been reported to reduce the risk of developing Alzheimer's disease (AD)." | 1.38 | No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease. ( Bayer, TA; Bulic, B; Demuth, HU; Hahn, S; Hillmann, A; Hoffmann, T; Schilling, S; Schneider-Axmann, T; Weggen, S; Wirths, O, 2012) |
| "Ibuprofen was found to down-regulate the TBI-induced inflammatory response." | 1.38 | Ibuprofen attenuates the inflammatory response and allows formation of migratory neuroblasts from grafted stem cells after traumatic brain injury. ( Forsberg-Nilsson, K; Hånell, A; Hillered, L; Holmqvist, K; Marklund, N; Wallenquist, U, 2012) |
| " We examined the possibility that concurrent blockade of free radicals and prostaglandin E(2) (PGE(2))-mediated inflammation might constitute a safe and effective therapeutic approach to ALS." | 1.38 | Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis. ( Cho, W; Gwag, BJ; Im, DS; Lee, JH; Lee, JK; Lee, YA; Lee, YB; Shin, JH; Springer, JE; Yun, BS, 2012) |
| "The neuronopathic forms of Gaucher's disease are characterized by severe neuronal loss, astrocytosis and microglial proliferation, but the cellular and molecular pathways causing these changes are not known." | 1.38 | Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease. ( Biton, I; Eilam, R; Farfel-Becker, T; Futerman, AH; Vitner, EB, 2012) |
| "Ibuprofen treatment also prevented the HI-induced loss O4- and O1-positive oligodendrocyte progenitor cells and myelin basic protein (MBP)-positive myelin content one week after P3 HI." | 1.37 | Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia-ischemia in the immature rodent brain. ( Buller, KM; Carty, ML; Colditz, PB; Gobe, G; Reinebrant, HE; Wixey, JA, 2011) |
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 1.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Salmani, H | 1 |
| Hosseini, M | 1 |
| Baghcheghi, Y | 1 |
| Samadi-Noshahr, Z | 1 |
| Corwin, C | 1 |
| Nikolopoulou, A | 1 |
| Pan, AL | 1 |
| Nunez-Santos, M | 1 |
| Vallabhajosula, S | 1 |
| Serrano, P | 1 |
| Babich, J | 1 |
| Figueiredo-Pereira, ME | 1 |
| Meunier, J | 1 |
| Borjini, N | 1 |
| Gillis, C | 1 |
| Villard, V | 1 |
| Maurice, T | 1 |
| Llorens-Martín, M | 1 |
| Jurado-Arjona, J | 1 |
| Fuster-Matanzo, A | 1 |
| Hernández, F | 1 |
| Rábano, A | 1 |
| Ávila, J | 1 |
| Tyagi, E | 1 |
| Agrawal, R | 1 |
| Nath, C | 2 |
| Shukla, R | 2 |
| Guo, J | 1 |
| Li, F | 1 |
| Wu, Q | 1 |
| Gong, Q | 1 |
| Lu, Y | 1 |
| Shi, J | 1 |
| Carty, ML | 1 |
| Wixey, JA | 1 |
| Reinebrant, HE | 1 |
| Gobe, G | 1 |
| Colditz, PB | 1 |
| Buller, KM | 1 |
| Hillmann, A | 1 |
| Hahn, S | 1 |
| Schilling, S | 1 |
| Hoffmann, T | 1 |
| Demuth, HU | 1 |
| Bulic, B | 1 |
| Schneider-Axmann, T | 1 |
| Bayer, TA | 1 |
| Weggen, S | 1 |
| Wirths, O | 1 |
| Wallenquist, U | 1 |
| Holmqvist, K | 1 |
| Hånell, A | 1 |
| Marklund, N | 1 |
| Hillered, L | 1 |
| Forsberg-Nilsson, K | 1 |
| Shin, JH | 1 |
| Lee, YA | 1 |
| Lee, JK | 1 |
| Lee, YB | 1 |
| Cho, W | 1 |
| Im, DS | 1 |
| Lee, JH | 1 |
| Yun, BS | 1 |
| Springer, JE | 1 |
| Gwag, BJ | 1 |
| Vitner, EB | 1 |
| Farfel-Becker, T | 1 |
| Eilam, R | 1 |
| Biton, I | 1 |
| Futerman, AH | 1 |
| Cao, T | 1 |
| Thomas, TC | 1 |
| Ziebell, JM | 1 |
| Pauly, JR | 1 |
| Lifshitz, J | 1 |
| Rai, S | 1 |
| Kamat, PK | 1 |
| Vlad, SC | 1 |
| Miller, DR | 1 |
| Kowall, NW | 1 |
| Felson, DT | 1 |
| Gamache, DA | 1 |
| Ellis, EF | 1 |
15 other studies available for ibuprofen and Brain Inflammation
| Article | Year |
|---|---|
The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Animal; | 2021 |
Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Disease Models, Animal; Enc | 2018 |
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Age | 2015 |
Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Disease Models, Animal; Encephal | 2014 |
Influence of LPS-induced neuroinflammation on acetylcholinesterase activity in rat brain.
Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cytokines; Disease Mo | 2008 |
Protective effects of icariin on brain dysfunction induced by lipopolysaccharide in rats.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Encephalitis; Epimedium; Flavonoids; Hippocampu | 2010 |
Ibuprofen inhibits neuroinflammation and attenuates white matter damage following hypoxia-ischemia in the immature rodent brain.
Topics: Animals; Animals, Newborn; Disease Models, Animal; Encephalitis; Humans; Hypoxia-Ischemia, Brain; Ib | 2011 |
No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Anti | 2012 |
Ibuprofen attenuates the inflammatory response and allows formation of migratory neuroblasts from grafted stem cells after traumatic brain injury.
Topics: Actins; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Cell | 2012 |
Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Anti-Infl | 2012 |
Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Antigens, Differen | 2012 |
Morphological and genetic activation of microglia after diffuse traumatic brain injury in the rat.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Calcium-Bind | 2012 |
A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cytokines; Disease Models, Animal; Dose-Res | 2013 |
Protective effects of NSAIDs on the development of Alzheimer disease.
Topics: Age Factors; Aged; Alzheimer Disease; Amyloid beta-Peptides; Anti-Inflammatory Agents, Non-Steroidal | 2008 |
Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Capillary Permeability; Carrageenan; Cerebrovascular | 1986 |