ibuprofen has been researched along with Brain Hemorrhage in 8 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| " High-dose ibuprofen and diclofenac were associated with increased risk of ischemic stroke [hazard ratio 2·15 (95% confidence interval 1·66-2·79) and 2·37 (confidence interval 1·99-2·81), respectively]." | 3.80 | Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety. ( Andersson, C; Fosbøl, EL; Gislason, GH; Kober, L; Olesen, JB; Olsen, AM; Torp-Pedersen, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zangbar, B | 1 |
| Pandit, V | 1 |
| Rhee, P | 1 |
| Khalil, M | 1 |
| Kulvatunyou, N | 1 |
| O'Keeffe, T | 1 |
| Tang, A | 1 |
| Gries, L | 1 |
| Green, DJ | 1 |
| Friese, RS | 1 |
| Joseph, B | 1 |
| Bauer, DF | 1 |
| Waters, AM | 1 |
| Tubbs, RS | 1 |
| Rozzelle, CJ | 1 |
| Wellons, JC | 1 |
| Blount, JP | 1 |
| Oakes, WJ | 1 |
| Mullins, ME | 1 |
| Empey, M | 1 |
| Jaramillo, D | 1 |
| Sosa, S | 1 |
| Human, T | 1 |
| Diringer, MN | 1 |
| Hunt, JC | 1 |
| Schneider, C | 1 |
| Menticoglou, S | 1 |
| Del Bigio, MR | 1 |
| Badjatia, N | 1 |
| Fanos, V | 1 |
| Pusceddu, M | 1 |
| Dessì, A | 1 |
| Marcialis, MA | 1 |
| Heo, MJ | 1 |
| Lee, OS | 1 |
| Lim, SC | 1 |
| Fosbøl, EL | 1 |
| Olsen, AM | 1 |
| Olesen, JB | 1 |
| Andersson, C | 1 |
| Kober, L | 1 |
| Torp-Pedersen, C | 1 |
| Gislason, GH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Comparative Study of the Efficacy of Common Antipyretic Treatments in Febrile Children[NCT02294071] | Phase 4 | 120 participants (Anticipated) | Interventional | 2014-12-31 | Not yet recruiting | ||
| Efficacy of Bromocriptine to Reduce Body Temperature in Febrile Critically-ill Adults With Acute Neurologic Disease: an Open-label, Blinded Endpoint, Randomized Controlled Trial[NCT03496545] | Phase 1/Phase 2 | 47 participants (Actual) | Interventional | 2018-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Mean total body temperature burden above 37°C over 48 hours during which patient receives either control or intervention medication. (NCT03496545)
Timeframe: over 48 hours
| Intervention | Temperature in degrees Celsius (Mean) |
|---|---|
| Acetaminophen | 37.8 |
| Bromocriptine and Acetaminophen | 37.7 |
Time in minutes where the temperature is ≥ 38.3ºC during the 48 hours of control versus intervention administration. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 216 |
| Bromocriptine and Acetaminophen | 300 |
Time in minutes it took after medication administration for the temperature to reach < 37.5ºC. (NCT03496545)
Timeframe: 48 hours
| Intervention | Minutes (Mean) |
|---|---|
| Acetaminophen | 253.5 |
| Bromocriptine and Acetaminophen | 556 |
Episodes of symptomatic hypotension, including decrease in supine systolic and diastolic pressures of greater than 20mm and 10mm Hg respectively with patient reported accompanying symptoms of light headedness or dizziness and incidence of nausea and headache. (NCT03496545)
Timeframe: Nursing assessment at every shift during 48 hour study period after first drug administration
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Decrease in blood pressure | Nausea | Headache | |
| Acetaminophen | 12 | 2 | 8 |
| Bromocriptine and Acetaminophen | 17 | 3 | 12 |
1 review available for ibuprofen and Brain Hemorrhage
| Article | Year |
|---|---|
Should we definitively abandon prophylaxis for patent ductus arteriosus in preterm new-borns?
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Extre | 2011 |
1 trial available for ibuprofen and Brain Hemorrhage
| Article | Year |
|---|---|
A prospective randomized study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.
Topics: Academic Medical Centers; Acetaminophen; Antipyretics; Body Temperature; Drug Therapy, Combination; | 2011 |
A prospective randomized study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.
Topics: Academic Medical Centers; Acetaminophen; Antipyretics; Body Temperature; Drug Therapy, Combination; | 2011 |
A prospective randomized study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.
Topics: Academic Medical Centers; Acetaminophen; Antipyretics; Body Temperature; Drug Therapy, Combination; | 2011 |
A prospective randomized study to evaluate the antipyretic effect of the combination of acetaminophen and ibuprofen in neurological ICU patients.
Topics: Academic Medical Centers; Acetaminophen; Antipyretics; Body Temperature; Drug Therapy, Combination; | 2011 |
6 other studies available for ibuprofen and Brain Hemorrhage
| Article | Year |
|---|---|
Clinical outcomes in patients on preinjury ibuprofen with traumatic brain injury.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Brain Injuries; Female; Hum | 2015 |
Safety and utility of scheduled nonnarcotic analgesic medications in children undergoing craniotomy for brain tumor.
Topics: Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; B | 2010 |
Fetal intracranial hemorrhage at 24 weeks' gestation.
Topics: Adolescent; Fatal Outcome; Female; Gestational Age; Humans; Ibuprofen; Intracranial Hemorrhages; Lab | 2011 |
Fever control in the NICU: is there still a simpler and cheaper solution?
Topics: Acetaminophen; Antipyretics; Fever; Humans; Ibuprofen; Intensive Care Units; Intracranial Hemorrhage | 2011 |
Comparative evaluation for the use of oral ibuprofen and intravenous indomethacin in Korean infants with patent ductus.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Comorbidity; Ductus Arteriosus, Paten | 2012 |
Use of nonsteroidal anti-inflammatory drugs among healthy people and specific cerebrovascular safety.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Ischemia; Cohort Studies; Denmark; Diclofenac; | 2014 |