ibuprofen has been researched along with Brain Hemorrhage, Cerebral in 18 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "A high dose of oral ibuprofen was associated with a higher likelihood of hemodynamically significant PDA closure vs standard doses of intravenous ibuprofen or intravenous indomethacin; placebo or no treatment did not significantly change the likelihood of mortality, necrotizing enterocolitis, or intraventricular hemorrhage." | 4.98 | Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis. ( Florez, ID; Mbuagbaw, L; Mitra, S; Sadeghirad, B; Tamayo, ME; Thabane, L; Vanniyasingam, T; Veroniki, AA; Zea, AM; Zhang, Y, 2018) |
| "Overall, the use of NSAIDs is not associated with an increased risk of hemorrhagic stroke, although this risk was modestly significantly elevated in diclofenac and meloxicam users." | 4.93 | Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies. ( Matteson, EL; Thongprayoon, C; Ungprasert, P, 2016) |
| "The occurrence of patent ductus arteriosus was less frequent only on day 3 of life in the ibuprofen group." | 2.71 | Prophylactic ibuprofen for the prevention of intraventricular hemorrhage among preterm infants: a multicenter, randomized study. ( Bertini, G; Dani, C; Guerrini, P; Martano, C; Pezzati, M; Poggi, C; Rubaltelli, FF, 2005) |
| "Ibuprofen treatment significantly reduced plasma levels of prostaglandins, and the levels remained low for 72 hours in newborns who received three doses of the drug." | 2.68 | Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants. ( Aranda, JV; Bardin, CL; Beharry, K; Chemtob, S; Papageorgiou, A; Varvarigou, A, 1996) |
| "Ibuprofen has less effect on blood flow velocity to important organs." | 2.66 | Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. ( Ohlsson, A; Shah, SS, 2020) |
| "Ibuprofen has less effect on blood flow velocity to important organs." | 2.61 | Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. ( Ohlsson, A; Shah, SS, 2019) |
| "Although the frequency of secondary patent ductus arteriosus (PDA) ligation and the incidence of bronchopulmonary dysplasia (BPD) was higher in the clinical symptoms group in the univariate analysis, after multivariate logistic regression analysis adjusting for the CRIB-II score, birthweight, birth year, and the invasive ventilator care ≤ 2 postnatal days, there were no significant differences in mortality, frequency of secondary ligation and in-hospital outcomes including necrotizing enterocolitis (NEC), intraventricular hemorrhage (IVH), BPD or death." | 1.46 | Comparison of the Mortality and In-Hospital Outcomes of Preterm Infants Treated with Ibuprofen for Patent Ductus Arteriosus with or without Clinical Symptoms Attributable to the Patent Ductus Arteriosus at the Time of Ibuprofen Treatment. ( Choi, CW; Jung, YH; Kim, BI; Kim, EK; Kim, HS; Lee, JA; Oh, S; Shin, SH; Sohn, JA; Yoo, H, 2017) |
| " Kinetic analyses assumed applicability of one open-compartment model and calculations from the model-independent areas under the time concentration curve (AUC)." | 1.30 | Pharmacokinetics and protein binding of intravenous ibuprofen in the premature newborn infant. ( Aranda, JV; Bansal, R; Bardin, C; Beharry, K; Chemtob, S; Modanlou, H; Papageorgiou, A; Varvarigou, A, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 4 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, CY | 1 |
| Chung, SH | 1 |
| Mitra, S | 2 |
| Hatfield, T | 1 |
| Campbell-Yeo, M | 1 |
| Dorling, J | 1 |
| Johnston, BC | 1 |
| Stróżyk, A | 1 |
| Paraskevas, T | 1 |
| Romantsik, O | 1 |
| Calevo, MG | 1 |
| Banzi, R | 1 |
| Ley, D | 1 |
| Bruschettini, M | 1 |
| Ohlsson, A | 2 |
| Shah, SS | 2 |
| Florez, ID | 1 |
| Tamayo, ME | 1 |
| Mbuagbaw, L | 1 |
| Vanniyasingam, T | 1 |
| Veroniki, AA | 1 |
| Zea, AM | 1 |
| Zhang, Y | 1 |
| Sadeghirad, B | 1 |
| Thabane, L | 1 |
| Ungprasert, P | 1 |
| Matteson, EL | 1 |
| Thongprayoon, C | 1 |
| Tofé Valera, I | 1 |
| Jaraba Caballero, MP | 1 |
| Ruiz González, MD | 1 |
| Rodríguez Benítez, MV | 1 |
| Parraga Quiles, MJ | 1 |
| Yoo, H | 1 |
| Lee, JA | 1 |
| Oh, S | 1 |
| Jung, YH | 1 |
| Sohn, JA | 1 |
| Shin, SH | 1 |
| Choi, CW | 1 |
| Kim, EK | 1 |
| Kim, HS | 1 |
| Kim, BI | 1 |
| Kalani, M | 1 |
| Shariat, M | 1 |
| Khalesi, N | 1 |
| Farahani, Z | 1 |
| Ahmadi, S | 1 |
| McCrea, HJ | 1 |
| Ment, LR | 1 |
| Meisel, C | 1 |
| Johne, A | 1 |
| Roots, I | 1 |
| Heyman, E | 1 |
| Morag, I | 1 |
| Batash, D | 1 |
| Keidar, R | 1 |
| Baram, S | 1 |
| Berkovitch, M | 1 |
| Hammerman, C | 1 |
| Kaplan, M | 1 |
| Dani, C | 1 |
| Bertini, G | 1 |
| Pezzati, M | 1 |
| Poggi, C | 1 |
| Guerrini, P | 1 |
| Martano, C | 1 |
| Rubaltelli, FF | 1 |
| Varvarigou, A | 2 |
| Bardin, CL | 1 |
| Beharry, K | 2 |
| Chemtob, S | 2 |
| Papageorgiou, A | 2 |
| Aranda, JV | 2 |
| Bansal, R | 1 |
| Bardin, C | 1 |
| Modanlou, H | 1 |
| Cotton, RB | 1 |
6 reviews available for ibuprofen and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews.
Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, N | 2023 |
Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Drug-Related Side Effects and Adverse Reactions; Duc | 2020 |
Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Bayes Theorem; Cerebral Hemorrhage | 2018 |
Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolit | 2019 |
Nonaspirin Nonsteroidal Anti-Inflammatory Drugs and Risk of Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cerebral Hemorrhage; Diclofenac; Humans; Ibuprof | 2016 |
The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Coagulants; Cyclooxygenase Inhibitors; Factor VIIa; Humans | 2008 |
4 trials available for ibuprofen and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
A Comparison of Early Ibuprofen and Indomethacin Administration to Prevent Intraventricular Hemorrhage Among Preterm Infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Cyclooxygenase Inhibitors; Ductus Arte | 2016 |
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Double-Blind Method; Humans; Ibuprofen | 2005 |
Prophylactic ibuprofen for the prevention of intraventricular hemorrhage among preterm infants: a multicenter, randomized study.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Double-Blind Method; Ductus A | 2005 |
Early ibuprofen administration to prevent patent ductus arteriosus in premature newborn infants.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Ductus Arteriosu | 1996 |
8 other studies available for ibuprofen and Brain Hemorrhage, Cerebral
| Article | Year |
|---|---|
Single-dose prophylactic ibuprofen therapy for patent ductus arteriosus in preterm infants.
Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant; Infant, Low Birth Weight; | 2022 |
Evaluation of Health-Related Values and Preferences of Adults Who Were Preterm Infants and Parents of Preterm Infants Concerning Use of Prophylactic Cyclooxygenase Inhibitor Drugs.
Topics: Acetaminophen; Adult; Cerebral Hemorrhage; Child; Cross-Sectional Studies; Cyclooxygenase Inhibitors | 2023 |
The Role of Paracetamol for Closing Patent Ductus Arteriosus. A Challenging Alternative for Ductal Closure?
Topics: Acetaminophen; Administration, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorr | 2016 |
Comparison of the Mortality and In-Hospital Outcomes of Preterm Infants Treated with Ibuprofen for Patent Ductus Arteriosus with or without Clinical Symptoms Attributable to the Patent Ductus Arteriosus at the Time of Ibuprofen Treatment.
Topics: Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Echocardiography; Entero | 2017 |
Fatal intracerebral mass bleeding associated with Ginkgo biloba and ibuprofen.
Topics: Aged; Cerebral Hemorrhage; Drug Interactions; Fatal Outcome; Ginkgo biloba; Humans; Ibuprofen; Male; | 2003 |
Closure of patent ductus arteriosus with oral ibuprofen suspension in premature newborns: a pilot study.
Topics: Administration, Oral; Cerebral Hemorrhage; Drug Evaluation; Ductus Arteriosus, Patent; Gestational A | 2003 |
Pharmacokinetics and protein binding of intravenous ibuprofen in the premature newborn infant.
Topics: Age Factors; Binding Sites; Cerebral Hemorrhage; Chromatography, High Pressure Liquid; Cyclooxygenas | 1997 |
Don't discard your indomethacin yet.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Brain; Cerebral Hemorrhage; Clinical Trials a | 2000 |