ibuprofen has been researched along with Brain Edema in 6 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 5.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| "Recently we reported that intrathalamic microinjection of carbachol triggers generalized convulsive seizures (GCS) followed by severe inflammatory response including edema, microhemorrhages, and subsequent degeneration of amygdaloallocortical area." | 3.76 | Aggravation of seizure-associated microvascular injuries by ibuprofen may involve multiple pathways. ( Mraovitch, S; Régnier, A; Vicaut, E, 2010) |
| " The authors have used the rat C6 glioma spheroid implantation model to compare the effects of two steroids (dexamethasone and methylprednisolone) and two NSAID's (ibuprofen and indomethacin) on protein extravasation caused by intracranial gliomas." | 3.67 | Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model. ( Del Maestro, RF; Farrell, CL; Reichman, HR, 1986) |
| "Ibuprofen is a prototypical nonsteroidal anti-inflammatory drug widely prescribed as an analgesic, anti-inflammatory, and antipyretic agent." | 2.48 | Acute Ibuprofen intoxication: report on a case and review of the literature. ( d'Aloja, E; De-Giorgio, F; Fucci, N; Lodise, M; Rossi, R, 2012) |
| "The congenital form, referred to as familial hemophagocytic lymphohistiocytosis (FHL), is often associated with cerebromeningeal involvement, whereas neurological complications are not characteristic of the adult form of secondary HLH (sHLH)." | 1.35 | Retinal microangiopathy and rapidly fatal cerebral edema in a patient with adult-onset Still's disease and concurrent macrophage activation syndrome. ( Fehr, J; Gianella, S; Heppner, FL; Kurrer, M; Schaer, DJ; Schwarz, U; Seebach, JD, 2008) |
| "A model of brain inflammation has recently been developed in mice using intraventricular injection of carrageenan (CAR)." | 1.27 | Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation. ( Ellis, EF; Gamache, DA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, JI | 1 |
| Holdridge, A | 1 |
| Mendizabal, JE | 1 |
| Régnier, A | 1 |
| Vicaut, E | 1 |
| Mraovitch, S | 1 |
| Lodise, M | 1 |
| De-Giorgio, F | 1 |
| Rossi, R | 1 |
| d'Aloja, E | 1 |
| Fucci, N | 1 |
| Gianella, S | 1 |
| Schaer, DJ | 1 |
| Schwarz, U | 1 |
| Kurrer, M | 1 |
| Heppner, FL | 1 |
| Fehr, J | 1 |
| Seebach, JD | 1 |
| Reichman, HR | 1 |
| Farrell, CL | 1 |
| Del Maestro, RF | 1 |
| Gamache, DA | 1 |
| Ellis, EF | 1 |
2 reviews available for ibuprofen and Brain Edema
| Article | Year |
|---|---|
Altitude headache.
Topics: Acute Disease; Adaptation, Physiological; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Asp | 2013 |
Acute Ibuprofen intoxication: report on a case and review of the literature.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Edema; Forensic Pathology; Forensic Toxicology; Gas C | 2012 |
4 other studies available for ibuprofen and Brain Edema
| Article | Year |
|---|---|
Aggravation of seizure-associated microvascular injuries by ibuprofen may involve multiple pathways.
Topics: Animals; Brain; Brain Edema; Carbachol; Cyclooxygenase Inhibitors; Disease Models, Animal; Ibuprofen | 2010 |
Retinal microangiopathy and rapidly fatal cerebral edema in a patient with adult-onset Still's disease and concurrent macrophage activation syndrome.
Topics: Adult; Brain Edema; Confusion; Drug Therapy, Combination; Early Diagnosis; Etanercept; Fatal Outcome | 2008 |
Effects of steroids and nonsteroid anti-inflammatory agents on vascular permeability in a rat glioma model.
Topics: Animals; Anti-Inflammatory Agents; Blood-Brain Barrier; Brain Edema; Brain Neoplasms; Capillary Perm | 1986 |
Effect of dexamethasone, indomethacin, ibuprofen, and probenecid on carrageenan-induced brain inflammation.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Capillary Permeability; Carrageenan; Cerebrovascular | 1986 |