ibuprofen has been researched along with Bone Fractures in 17 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our objective was to determine whether morphine administered orally has superior efficacy to ibuprofen in fracture-related pain." | 9.19 | Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial. ( Ali, S; Bale, M; Bhullar, G; Howard, J; Langford, C; Lim, R; Lin, K; Mainprize, D; Papini, A; Poonai, N; Rieder, MJ; Stitt, L; Teefy, J, 2014) |
| "To compare the efficacy of a combination of codeine with ibuprofen to ibuprofen alone on the intensity of pain experienced by children presenting to the ED with a musculoskeletal trauma to a limb." | 9.17 | Efficacy of an ibuprofen/codeine combination for pain management in children presenting to the emergency department with a limb injury: a pilot study. ( Fortin, C; Gouin, S; Julien, M; Le May, S; Messier, A; Robert, MA, 2013) |
| "We compare the treatment of pain in children with arm fractures by ibuprofen 10 mg/kg versus acetaminophen with codeine 1 mg/kg/dose (codeine component)." | 9.14 | A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain. ( Brousseau, DC; Drendel, AL; Gorelick, MH; Kim, MK; Lyon, R; Weisman, SJ, 2009) |
| "This prospective, randomized, double-blinded, clinical trial compared the effectiveness of oxycodone, ibuprofen, and the combination in children (age, 6-18 years), with pain from a suspected orthopedic injury." | 9.12 | Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children. ( Godambe, SA; Koller, DM; Lorenz, D; Myers, AB, 2007) |
| " Our objective was to determine whether morphine administered orally has superior efficacy to ibuprofen in fracture-related pain." | 5.19 | Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial. ( Ali, S; Bale, M; Bhullar, G; Howard, J; Langford, C; Lim, R; Lin, K; Mainprize, D; Papini, A; Poonai, N; Rieder, MJ; Stitt, L; Teefy, J, 2014) |
| "To compare the efficacy of a combination of codeine with ibuprofen to ibuprofen alone on the intensity of pain experienced by children presenting to the ED with a musculoskeletal trauma to a limb." | 5.17 | Efficacy of an ibuprofen/codeine combination for pain management in children presenting to the emergency department with a limb injury: a pilot study. ( Fortin, C; Gouin, S; Julien, M; Le May, S; Messier, A; Robert, MA, 2013) |
| "We compare the treatment of pain in children with arm fractures by ibuprofen 10 mg/kg versus acetaminophen with codeine 1 mg/kg/dose (codeine component)." | 5.14 | A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain. ( Brousseau, DC; Drendel, AL; Gorelick, MH; Kim, MK; Lyon, R; Weisman, SJ, 2009) |
| "This prospective, randomized, double-blinded, clinical trial compared the effectiveness of oxycodone, ibuprofen, and the combination in children (age, 6-18 years), with pain from a suspected orthopedic injury." | 5.12 | Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children. ( Godambe, SA; Koller, DM; Lorenz, D; Myers, AB, 2007) |
| "To quantify the frequency and intensity of adverse events (AEs), commonly known as side effects, experienced by children receiving either ibuprofen or oxycodone for pain management following an acute fracture." | 4.12 | Quantifying the intensity of adverse events with ibuprofen and oxycodone: an observational cohort study. ( Ali, S; Carleton, B; Drendel, AL; Gourlay, K; Johnson, DW; Le May, S; Ortiz, S; Rosychuk, RJ; Watts, R; Yukseloglu, A, 2022) |
| "Ibuprofen is an effective medication for fracture pain in children and its use does not impair clinical or radiographic long bone fracture healing in skeletally immature patients." | 2.94 | Effect of NSAID Use on Bone Healing in Pediatric Fractures: A Preliminary, Prospective, Randomized, Blinded Study. ( Coe, KM; Cook, JL; Gupta, SK; Hoernschemeyer, DG; Nuelle, JAV; Oliver, HA, 2020) |
| "Ibuprofen appears to be a safe option for fracture-related pain." | 1.62 | An observational cohort study comparing ibuprofen and oxycodone in children with fractures. ( Ali, S; Carleton, B; Drendel, AL; Johnson, DW; LeMay, S; Manaloor, R; McGrath, PJ; Rosychuk, RJ, 2021) |
| " The purpose of this study was to examine opioid use in the pediatric fracture population by determining and comparing the average hospital opioid dosage utilized in the operative pediatric elbow and femur fractures and determining and comparing the average dose prescribed following operative treatment of elbow and femur fractures." | 1.51 | Opioid Use Following Operatively Treated Pediatric Elbow and Femur Fractures. ( Krucylak, P; Meyer, ZI; Miller, ML; Mo, M; Wall, LB, 2019) |
| "Ibuprofen treatment caused persistence of cartilage within the fracture callus and reduced peak torque at 6 weeks after osteotomy as compared to the fibulas from the placebo-treated rabbits." | 1.35 | A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing. ( Bontempo, N; Capo, JT; Cottrell, JA; Manigrasso, MB; O'Connor, JP; Parsons, JR; Tan, V, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, S | 3 |
| Manaloor, R | 1 |
| Johnson, DW | 2 |
| Rosychuk, RJ | 2 |
| LeMay, S | 1 |
| Carleton, B | 2 |
| McGrath, PJ | 1 |
| Drendel, AL | 3 |
| Gourlay, K | 1 |
| Yukseloglu, A | 1 |
| Ortiz, S | 1 |
| Watts, R | 1 |
| Le May, S | 2 |
| Atalay, YO | 1 |
| Mursel, E | 1 |
| Ciftci, B | 1 |
| Iptec, G | 1 |
| Nuelle, JAV | 1 |
| Coe, KM | 1 |
| Oliver, HA | 1 |
| Cook, JL | 1 |
| Hoernschemeyer, DG | 1 |
| Gupta, SK | 1 |
| Meyer, ZI | 1 |
| Krucylak, P | 1 |
| Mo, M | 1 |
| Miller, ML | 1 |
| Wall, LB | 1 |
| Poonai, N | 1 |
| Bhullar, G | 1 |
| Lin, K | 1 |
| Papini, A | 1 |
| Mainprize, D | 1 |
| Howard, J | 1 |
| Teefy, J | 1 |
| Bale, M | 1 |
| Langford, C | 1 |
| Lim, R | 1 |
| Stitt, L | 1 |
| Rieder, MJ | 1 |
| Parish, E | 1 |
| Lim, KB | 1 |
| DePeter, KC | 1 |
| Blumberg, SM | 1 |
| Dienstag Becker, S | 1 |
| Meltzer, JA | 1 |
| Gorelick, MH | 1 |
| Weisman, SJ | 1 |
| Lyon, R | 1 |
| Brousseau, DC | 1 |
| Kim, MK | 1 |
| O'Connor, JP | 1 |
| Capo, JT | 1 |
| Tan, V | 1 |
| Cottrell, JA | 1 |
| Manigrasso, MB | 1 |
| Bontempo, N | 1 |
| Parsons, JR | 1 |
| Shepherd, M | 1 |
| Aickin, R | 1 |
| Morris, L | 1 |
| Stulberg, D | 1 |
| Stevermer, JJ | 1 |
| Kidd, LJ | 1 |
| Cowling, NR | 1 |
| Wu, AC | 1 |
| Kelly, WL | 1 |
| Forwood, MR | 1 |
| Gouin, S | 1 |
| Fortin, C | 1 |
| Messier, A | 1 |
| Robert, MA | 1 |
| Julien, M | 1 |
| Koller, DM | 1 |
| Myers, AB | 1 |
| Lorenz, D | 1 |
| Godambe, SA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Ultrasound-guided Clavipectoral Fascia Plane Block and Interscalen Brachial Plexus Block for Analgesia After Clavicle Surgery[NCT04332497] | 0 participants (Actual) | Interventional | 2020-04-10 | Withdrawn (stopped due to no participants) | |||
| The Effectiveness of Clavipectoral Fascia Plane Block for Analgesia After Clavicle Surgery: Randomized, Prospective Study[NCT04328558] | 0 participants (Actual) | Interventional | 2020-04-22 | Withdrawn (stopped due to no participants) | |||
| The Effect of Clavipectoral Fascia Plane Block on Pain Management and Patient Satisfaction Following Clavicle Surgery: Randomized, Prospective Study[NCT05268874] | 38 participants (Actual) | Interventional | 2022-03-18 | Completed | |||
| Comparison of Analgesic Efficacy of Dexketoprofen and Ibuprofen in Long Bone Fractures: Randomised Controlled Double-blind Study[NCT06060236] | Phase 4 | 100 participants (Anticipated) | Interventional | 2023-09-01 | Recruiting | ||
| Oral Morphine Versus Ibuprofen for Post-fracture Pain Management in Children: a Randomized Controlled Study[NCT01690780] | 183 participants (Actual) | Interventional | 2012-09-30 | Completed | |||
| A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy[NCT01267136] | Phase 4 | 84 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Ibuprofen vs. Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?[NCT01605240] | 50 participants (Anticipated) | Interventional | 2012-07-31 | Recruiting | |||
| Phase III Clinical Trial Studying Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children[NCT02477007] | Phase 3 | 304 participants (Actual) | Interventional | 2015-12-03 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Average number of post-operative days with pain score >4/10. Pain score assessments were administered once daily by parents using either the Numeric Rating Scale (NRS-11) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 8-15 (von Baeyer et al., 2009) or the Faces Pain Scale-Revised (FPS-R) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 4-10 (Hicks et al., 2001). (NCT01267136)
Timeframe: Efficacy was assessed daily during the 10-day postoperative recovery period.
| Intervention | days (Median) |
|---|---|
| Capital® With Codeine Suspension | 1.5 |
| Tramadol Suspension | 1 |
Parent-reported side effects entered in 10-day diary. (NCT01267136)
Timeframe: Side effects will be observed and recorded daily by caregivers for a total of 10 days in the take-home diary.
| Intervention | participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Nausea | Vomiting | Fever | Itching | Rash | Sweating | Dizziness | Headache | Constipation | Oversedation | Tonsil bleed | |
| Capital® With Codeine Suspension | 20 | 21 | 11 | 5 | 1 | 9 | 15 | 12 | 21 | 14 | 3 |
| Tramadol Suspension | 20 | 18 | 10 | 12 | 1 | 7 | 17 | 17 | 21 | 8 | 0 |
7 trials available for ibuprofen and Bone Fractures
| Article | Year |
|---|---|
Effect of NSAID Use on Bone Healing in Pediatric Fractures: A Preliminary, Prospective, Randomized, Blinded Study.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Fracture Healing; Fractures, Bon | 2020 |
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Double-Blind Method; Fema | 2014 |
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Double-Blind Method; Fema | 2014 |
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Double-Blind Method; Fema | 2014 |
Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Double-Blind Method; Fema | 2014 |
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain.
Topics: Acetaminophen; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschool; Codeine; Double-Blind | 2009 |
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain.
Topics: Acetaminophen; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschool; Codeine; Double-Blind | 2009 |
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain.
Topics: Acetaminophen; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschool; Codeine; Double-Blind | 2009 |
A randomized clinical trial of ibuprofen versus acetaminophen with codeine for acute pediatric arm fracture pain.
Topics: Acetaminophen; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschool; Codeine; Double-Blind | 2009 |
Paracetamol versus ibuprofen: a randomized controlled trial of outpatient analgesia efficacy for paediatric acute limb fractures.
Topics: Acetaminophen; Acute Disease; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analysis of Var | 2009 |
...And what's best for fracture pain in children?
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Codeine; Drug Combin | 2009 |
Efficacy of an ibuprofen/codeine combination for pain management in children presenting to the emergency department with a limb injury: a pilot study.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Codeine; Contusions; | 2013 |
Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Ch | 2007 |
Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Ch | 2007 |
Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Ch | 2007 |
Effectiveness of oxycodone, ibuprofen, or the combination in the initial management of orthopedic injury-related pain in children.
Topics: Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Ch | 2007 |
10 other studies available for ibuprofen and Bone Fractures
| Article | Year |
|---|---|
An observational cohort study comparing ibuprofen and oxycodone in children with fractures.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Co | 2021 |
Quantifying the intensity of adverse events with ibuprofen and oxycodone: an observational cohort study.
Topics: Analgesics, Opioid; Child; Cohort Studies; Constipation; Double-Blind Method; Fractures, Bone; Human | 2022 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Clavipectoral Fascia Plane Block for Analgesia after Clavicle Surgery.
Topics: Anesthetics, Local; Bupivacaine; Cervical Plexus Block; Clavicle; Fascia; Female; Fractures, Bone; H | 2019 |
Opioid Use Following Operatively Treated Pediatric Elbow and Femur Fractures.
Topics: Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; | 2019 |
Ibuprofen as effective as morphine for fracture pain in children, study shows.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Fractures, Bone; Humans; Ibuprofen; Morphine; M | 2014 |
Postfracture pain in children can be adequately managed with ibuprofen.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Fractures, Bone; Humans; Ibuprofen; Male; Morp | 2015 |
Does the Use of Ibuprofen in Children with Extremity Fractures Increase their Risk for Bone Healing Complications?
Topics: Adolescent; Analgesics; Chi-Square Distribution; Child; Child, Preschool; Female; Femoral Fractures; | 2017 |
A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomechanical Phenomena; | 2009 |
Fracture pain relief for kids? Ibuprofen does it better.
Topics: Analgesics, Non-Narcotic; Arm Injuries; Child; Fracture Healing; Fractures, Bone; Humans; Ibuprofen; | 2010 |
Selective and non-selective cyclooxygenase inhibitors delay stress fracture healing in the rat ulna.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Remodeling; Bone Resorption; Complement C5a; | 2013 |