Page last updated: 2024-10-28

ibuprofen and Bacterial Disease

ibuprofen has been researched along with Bacterial Disease in 16 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"to compare the antipyretic effects of ibuprofen in febrile children with serious bacterial infections (SBI), and children with a presumed viral infection."8.02Fever response to ibuprofen in viral and bacterial childhood infections. ( Barkan Perl, S; Breitbart, R; Gamsu, S; Gelernter, R; Goldman, M; Kozer, E; Lazarovitch, Z; Ophir, N; Oren-Amit, A; Youngster, I, 2021)
"During bacterial infection, reactive oxygen species (ROS) and other signaling pathways are activated, which intensify inflammation and increase ALI-related mortality and morbidity."5.91Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury. ( Cao, H; Chen, W; Feng, B; Gao, C; Muhammad, W; Wang, R; Wang, S; Xie, J; Xu, Y; Yao, Q; Yu, Y; Zhang, Y; Zhou, J; Zhu, J, 2023)
"to compare the antipyretic effects of ibuprofen in febrile children with serious bacterial infections (SBI), and children with a presumed viral infection."4.02Fever response to ibuprofen in viral and bacterial childhood infections. ( Barkan Perl, S; Breitbart, R; Gamsu, S; Gelernter, R; Goldman, M; Kozer, E; Lazarovitch, Z; Ophir, N; Oren-Amit, A; Youngster, I, 2021)
"59 liters/kg), but the median serum half-life (16."2.71Effects of co-administration of ibuprofen-lysine on the pharmacokinetics of amikacin in preterm infants during the first days of life. ( Allegaert, K; Cossey, V; Devlieger, H; Langhendries, JP; Naulaers, G; Van Overmeire, B; Vanhole, C, 2004)
"This may occasionally cause an autoimmune haemolytic anaemia."2.36[Clinical significance and pathogenesis of drug- or microbe-induced autoimmune hemolytic anemias]. ( Maas, D; Schubothe, H; Weber, S, 1983)
"During bacterial infection, reactive oxygen species (ROS) and other signaling pathways are activated, which intensify inflammation and increase ALI-related mortality and morbidity."1.91Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury. ( Cao, H; Chen, W; Feng, B; Gao, C; Muhammad, W; Wang, R; Wang, S; Xie, J; Xu, Y; Yao, Q; Yu, Y; Zhang, Y; Zhou, J; Zhu, J, 2023)
"However, bacterial infections are important causes of high fever in patients receiving myelosuppressive chemotherapy, and such fevers persist despite the use of COX inhibitors."1.33Endotoxin fever in granulocytopenic rats: evidence that brain cyclooxygenase-2 is more important than circulating prostaglandin E(2). ( Dascombe, MJ; Maldonado, R; Miñano, FJ; Tavares, E, 2006)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's5 (31.25)18.2507
2000's3 (18.75)29.6817
2010's3 (18.75)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Muhammad, W1
Zhang, Y1
Zhu, J1
Xie, J1
Wang, S1
Wang, R1
Feng, B1
Zhou, J1
Chen, W1
Xu, Y1
Yao, Q1
Yu, Y1
Cao, H1
Gao, C1
Abd Elsalam, EA1
Shabaiek, HF1
Abdelaziz, MM1
Khalil, IA1
El-Sherbiny, IM1
Gelernter, R1
Ophir, N1
Goldman, M1
Lazarovitch, Z1
Gamsu, S1
Oren-Amit, A1
Breitbart, R1
Barkan Perl, S1
Kozer, E1
Youngster, I1
Chmiel, JF1
Konstan, MW1
Elborn, JS1
Vale, PF1
Fenton, A1
Brown, SP1
Bleidorn, J1
Hummers-Pradier, E1
Schmiemann, G1
Wiese, B1
Gágyor, I1
Allegaert, K2
Cossey, V2
Langhendries, JP1
Naulaers, G1
Vanhole, C1
Devlieger, H1
Van Overmeire, B1
Anderson, BJ1
Holford, NH1
Tavares, E1
Miñano, FJ1
Maldonado, R1
Dascombe, MJ1
Schubothe, H1
Maas, D1
Weber, S1
Haffajee, AD1
Dibart, S1
Kent, RL1
Socransky, SS1
Hockertz, S1
Heckenberger, R1
Ertel, W1
Morrison, MH1
Wang, P1
Ba, ZF1
Ayala, A1
Chaudry, IH1
Fletcher, JR1
Schneidkraut, MJ1
Carlson, RW1
Gnidec, AG1
Sibbald, WJ1
Cheung, H1
Metz, CA1

Reviews

2 reviews available for ibuprofen and Bacterial Disease

ArticleYear
Antibiotic and anti-inflammatory therapies for cystic fibrosis.
    Cold Spring Harbor perspectives in medicine, 2013, Oct-01, Volume: 3, Issue:10

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibiotic Prophylaxis; An

2013
[Clinical significance and pathogenesis of drug- or microbe-induced autoimmune hemolytic anemias].
    Immunitat und Infektion, 1983, Volume: 11, Issue:1

    Topics: Adult; Anemia, Hemolytic, Autoimmune; Bacterial Infections; Female; Humans; Ibuprofen; Infections; L

1983

Trials

3 trials available for ibuprofen and Bacterial Disease

ArticleYear
Recurrent urinary tract infections and complications after symptomatic versus antibiotic treatment: follow-up of a randomised controlled trial.
    German medical science : GMS e-journal, 2016, Volume: 14

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacterial I

2016
Effects of co-administration of ibuprofen-lysine on the pharmacokinetics of amikacin in preterm infants during the first days of life.
    Biology of the neonate, 2004, Volume: 86, Issue:3

    Topics: Amikacin; Bacterial Infections; Double-Blind Method; Gestational Age; Half-Life; Humans; Ibuprofen;

2004
Clinical and microbiological changes associated with the use of 4 adjunctive systemically administered agents in the treatment of periodontal infections.
    Journal of clinical periodontology, 1995, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Aged; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial

1995

Other Studies

11 other studies available for ibuprofen and Bacterial Disease

ArticleYear
Co-delivery of azithromycin and ibuprofen by ROS-responsive polymer nanoparticles synergistically attenuates the acute lung injury.
    Biomaterials advances, 2023, Volume: 154

    Topics: Acute Lung Injury; Azithromycin; Bacterial Infections; Humans; Ibuprofen; Inflammation; Nanoparticle

2023
Fortified hyperbranched PEGylated chitosan-based nano-in-micro composites for treatment of multiple bacterial infections.
    International journal of biological macromolecules, 2020, Apr-01, Volume: 148

    Topics: Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Bentonite; Chit

2020
Fever response to ibuprofen in viral and bacterial childhood infections.
    The American journal of emergency medicine, 2021, Volume: 46

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Bacterial Infections; Cross-Sectional

2021
Limiting damage during infection: lessons from infection tolerance for novel therapeutics.
    PLoS biology, 2014, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Adhesion; Bacterial Infections; Bacteria

2014
Limited predictability of amikacin clearance in extreme premature neonates at birth.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:1

    Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bact

2006
Endotoxin fever in granulocytopenic rats: evidence that brain cyclooxygenase-2 is more important than circulating prostaglandin E(2).
    Journal of leukocyte biology, 2006, Volume: 80, Issue:6

    Topics: Animals; Bacterial Infections; Brain; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Fev

2006
Treatment of an acute bacterial infection with a combination of acetylsalicylic acid/ibuprofen and interferon gamma.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bacterial Infections; Colony Count, Micro

1996
The complex pattern of cytokines in sepsis. Association between prostaglandins, cachectin, and interleukins.
    Annals of surgery, 1991, Volume: 214, Issue:2

    Topics: Animals; Bacterial Infections; Cytokines; Dinoprostone; Endotoxins; Ibuprofen; In Vitro Techniques;

1991
Ibuprofen in patients with severe sepsis.
    Critical care medicine, 1991, Volume: 19, Issue:11

    Topics: Bacterial Infections; Humans; Ibuprofen; Prostaglandin-Endoperoxide Synthases

1991
Bacterial sepsis-induced decrease in lung vascular reactivity to 9,11-dideoxy-11a9a-epoxymethano-prostaglandin F2 alpha (U46619) in the rat.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bacterial Infections; C

1990
Ibuprofen reduces the progression of permeability edema in an animal model of hyperdynamic sepsis.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:3

    Topics: Animals; Bacterial Infections; Disease Models, Animal; Hemodynamics; Hypertension, Pulmonary; Ibupro

1988