Page last updated: 2024-10-28

ibuprofen and Arrhythmia

ibuprofen has been researched along with Arrhythmia in 18 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure increases the risk of developing life-threatening ventricular arrhythmias."7.69Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. ( Crowell, SP; Ellis, BE; Hertz, RP; Louv, W; Moyé, L; Pratt, CM, 1994)
"The perfusion with ibuprofen, indomethacin and diclofenac in commonly used doses raised the arrhythmia susceptibility in an established rabbit whole-heart model while APD shortening and shortened ERP seem to be crucial for arrhythmogenesis."4.12Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model. ( Bäumer, S; Eckardt, L; Ellermann, C; Fehr, M; Frommeyer, G; Leitz, PR; Wegner, F; Willy, K; Wolfes, J, 2022)
"The ECG recording revealed that ibuprofen could induce arrhythmias, both in vitro and in vivo."3.74Possible arrhythmiogenic mechanism produced by ibuprofen. ( Li, CZ; Liu, YM; Wang, HW; Yang, ZF; Zhang, Y; Zheng, YQ, 2008)
"An observational, historical cohort evaluation was performed to examine the hypothesis that terfenadine (Seldane) exposure increases the risk of developing life-threatening ventricular arrhythmias."3.69Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine. ( Crowell, SP; Ellis, BE; Hertz, RP; Louv, W; Moyé, L; Pratt, CM, 1994)
"Arrhythmias were produced by ouabain (2."3.67Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain. ( Ferrier, GR; Karmazyn, M; Moffat, MP, 1985)
"Ibuprofen is a widely used nonsteroidal anti-inflammatory drug, which has recently been associated with increased cardiovascular risk, but its electrophysiological effects have not yet been properly studied in isolated cardiac preparations."1.62Cardiac electrophysiological effects of ibuprofen in dog and rabbit ventricular preparations: possible implication to enhanced proarrhythmic risk. ( Árpádffy-Lovas, T; Gazdag, P; Györe, B; Jost, N; Koncz, I; Magyar, T; Nagy, N; Naveed, M; Pászti, B; Prorok, J; Szlovák, J; Topál, L; Varró, A; Virág, L, 2021)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's5 (27.78)18.2507
2000's1 (5.56)29.6817
2010's3 (16.67)24.3611
2020's4 (22.22)2.80

Authors

AuthorsStudies
Vivier, D1
Bennis, K1
Lesage, F1
Ducki, S1
Wolfes, J1
Ellermann, C1
Bäumer, S1
Fehr, M1
Willy, K1
Wegner, F1
Leitz, PR1
Eckardt, L1
Frommeyer, G1
Isbister, GK1
Polanski, R1
Cooper, JM1
Keegan, M1
Isoardi, KZ1
van Ham, WB1
Cornelissen, CM1
van Veen, TAB1
Pászti, B1
Prorok, J1
Magyar, T1
Árpádffy-Lovas, T1
Györe, B1
Topál, L1
Gazdag, P1
Szlovák, J1
Naveed, M1
Jost, N1
Nagy, N1
Varró, A1
Virág, L1
Koncz, I1
Imazio, M1
Brucato, A1
Barbieri, A1
Ferroni, F1
Maestroni, S1
Ligabue, G1
Chinaglia, A1
Cumetti, D1
Della Casa, G1
Bonomi, F1
Mantovani, F1
Di Corato, P1
Lugli, R1
Faletti, R1
Leuzzi, S1
Bonamini, R1
Modena, MG1
Belli, R1
Schmidt, JJ1
Ramazan, L1
Bockemeyer, C1
Günter, HH1
Martens-Lobenhoffer, J1
Ganzenmüller, T1
Bode-Böger, SM1
Kielstein, JT1
Yang, ZF1
Wang, HW1
Zheng, YQ1
Zhang, Y1
Liu, YM1
Li, CZ1
Jugdutt, BI1
Burkhart, GA1
Freiman, J1
Pratt, CM1
Hertz, RP1
Ellis, BE1
Crowell, SP1
Louv, W1
Moyé, L1
Masud, T1
Winocour, P1
Clarke, F1
Cimpello, LB1
Craig, S1
Lawrence, E1
Baker, MD1
Wilkerson, RD1
Glenn, TM1
Bernier, M1
Alyea, EP1
Hearse, DJ1
Moffat, MP2
Ferrier, GR2
Karmazyn, M2
Kostecka-Pokryszko, A1
Mulczyk, M1
Cierlińska, M1
Strusińska, H1

Reviews

2 reviews available for ibuprofen and Arrhythmia

ArticleYear
Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?
    Journal of medicinal chemistry, 2016, 06-09, Volume: 59, Issue:11

    Topics: Arrhythmias, Cardiac; Depression; Epilepsy; Humans; Inflammation; Models, Molecular; Molecular Struc

2016
Uremic toxins in chronic kidney disease highlight a fundamental gap in understanding their detrimental effects on cardiac electrophysiology and arrhythmogenesis.
    Acta physiologica (Oxford, England), 2022, Volume: 236, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Cardio-Renal Syndrome; Cardiovascular Diseases; Electrophysiologic Te

2022

Other Studies

16 other studies available for ibuprofen and Arrhythmia

ArticleYear
Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model.
    Basic & clinical pharmacology & toxicology, 2022, Volume: 130, Issue:1

    Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Cardiac E

2022
Duloxetine overdose causes sympathomimetic and serotonin toxicity without major complications.
    Clinical toxicology (Philadelphia, Pa.), 2022, Volume: 60, Issue:9

    Topics: Acetaminophen; Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coma; Diazepam; Droperidol; Drug

2022
Cardiac electrophysiological effects of ibuprofen in dog and rabbit ventricular preparations: possible implication to enhanced proarrhythmic risk.
    Canadian journal of physiology and pharmacology, 2021, Volume: 99, Issue:1

    Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Dogs; Dos

2021
Good prognosis for pericarditis with and without myocardial involvement: results from a multicenter, prospective cohort study.
    Circulation, 2013, Jul-02, Volume: 128, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal;

2013
Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.
    BMC nephrology, 2016, Mar-15, Volume: 17

    Topics: Acute Disease; Acute Kidney Injury; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal;

2016
Possible arrhythmiogenic mechanism produced by ibuprofen.
    Acta pharmacologica Sinica, 2008, Volume: 29, Issue:4

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship

2008
Effect of PGE1, PGE2 and PGI2 on ventricular arrhythmias during myocardial infarction in conscious dogs: relation to infarct size.
    Prostaglandins and medicine, 1981, Volume: 7, Issue:5

    Topics: Alprostadil; Animals; Arrhythmias, Cardiac; Collateral Circulation; Dinoprostone; Dogs; Electrocardi

1981
The risk of life-threatening cardiovascular events with terfenadine.
    The American journal of cardiology, 1995, Jan-15, Volume: 75, Issue:2

    Topics: Arrhythmias, Cardiac; Clemastine; Humans; Ibuprofen; Risk Factors; Terfenadine; Ventricular Dysfunct

1995
Risk of developing life-threatening ventricular arrhythmia associated with tefenadine in comparison with over-the-counter antihistamines, ibuprofen and clemastine.
    The American journal of cardiology, 1994, Feb-15, Volume: 73, Issue:5

    Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Clemastine; Cohort Studies; Death, Sudden, Cardiac;

1994
Reversible hyporeninaemic hypoaldosteronism and life-threatening cardiac dysrhythmias: the interaction of non-steroidal anti-inflammatory drugs and autonomic dysfunction.
    Postgraduate medical journal, 1993, Volume: 69, Issue:813

    Topics: Arrhythmias, Cardiac; Humans; Hyperkalemia; Hypoaldosteronism; Ibuprofen; Male; Middle Aged

1993
A calcium channel blocker and ibuprofen overdose.
    Current opinion in pediatrics, 1998, Volume: 10, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Calcium Channel Blockers;

1998
Influence of nonsteroidal anti-inflammatory drugs on ouabain toxicity.
    American heart journal, 1977, Volume: 94, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Aspirin; Cyclooxygenase Inhibitors; Dogs; F

1977
Reperfusion-induced arrhythmias are not prevented by ibuprofen in isolated rat heart.
    Free radical biology & medicine, 1990, Volume: 8, Issue:6

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; Coronary Circulation; Cyclooxyge

1990
A direct role of endogenous prostaglandins in reperfusion-induced cardiac arrhythmias.
    Canadian journal of physiology and pharmacology, 1989, Volume: 67, Issue:7

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Dinoprost; Dogs; Heart Conduction System; Ibuprofen; In Vitr

1989
[ECG changes in the ST-T syndrome after treatment with ibuprofen].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Nov-15, Volume: 39, Issue:22

    Topics: Arrhythmias, Cardiac; Electrocardiography; Endocarditis, Bacterial; Humans; Ibuprofen; Male; Middle

1986
Prostaglandin involvement in hypersensitivity of ischemic hearts to arrhythmogenic influence of ouabain.
    The American journal of physiology, 1985, Volume: 249, Issue:1 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Arrhythmias, Cardiac; As

1985