ibuprofen has been researched along with Anxiety in 10 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Anxiety: Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One arm was given sugar-free chewing gum and the other arm ibuprofen for pain relief." | 9.24 | Chewing gum vs. ibuprofen in the management of orthodontic pain, a multi-centre randomised controlled trial - the effect of anxiety. ( Atack, NE; Bradley, R; Deacon, S; Ellis, P; Ewings, P; Griffiths, H; House, K; Ireland, AJ; Jordan, A; Moore, MB; Sandy, JR; Scaysbrook, E; Wenger, N; Williams, JC; Worth, V, 2017) |
| "Group A, receiving ibuprofen before and after separator placement, experienced significantly less pain (P <0." | 9.14 | Effects of preoperative ibuprofen on pain after separator placement. ( Fillingim, R; Logan, H; Marris, CK; McGorray, SP; Minor, V; Wheeler, TT; Yezierski, R, 2009) |
| "The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors." | 8.02 | The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021) |
| "To assess pain-management using auricular acupuncture as an adjunct to ibuprofen and paracervical block during first trimester uterine aspiration, and to assess auricular acupuncture's effect on anxiety." | 5.30 | Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial. ( Danvers, A; Gold, MA; Morrow, L; Ndubisi, C; Westhoff, CL, 2019) |
| " One arm was given sugar-free chewing gum and the other arm ibuprofen for pain relief." | 5.24 | Chewing gum vs. ibuprofen in the management of orthodontic pain, a multi-centre randomised controlled trial - the effect of anxiety. ( Atack, NE; Bradley, R; Deacon, S; Ellis, P; Ewings, P; Griffiths, H; House, K; Ireland, AJ; Jordan, A; Moore, MB; Sandy, JR; Scaysbrook, E; Wenger, N; Williams, JC; Worth, V, 2017) |
| "Group A, receiving ibuprofen before and after separator placement, experienced significantly less pain (P <0." | 5.14 | Effects of preoperative ibuprofen on pain after separator placement. ( Fillingim, R; Logan, H; Marris, CK; McGorray, SP; Minor, V; Wheeler, TT; Yezierski, R, 2009) |
| "The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors." | 4.02 | The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bahrami, T | 1 |
| Yaghmaei, P | 1 |
| Yousofvand, N | 1 |
| Chen, ZJ | 3 |
| Su, CW | 3 |
| Xiong, S | 3 |
| Li, T | 3 |
| Liang, HY | 3 |
| Lin, YH | 3 |
| Chang, L | 3 |
| Wu, HY | 3 |
| Li, F | 4 |
| Zhu, DY | 3 |
| Luo, CX | 3 |
| Salmani, H | 1 |
| Hosseini, M | 1 |
| Baghcheghi, Y | 1 |
| Samadi-Noshahr, Z | 1 |
| Ndubisi, C | 1 |
| Danvers, A | 1 |
| Gold, MA | 1 |
| Morrow, L | 1 |
| Westhoff, CL | 2 |
| Shang, L | 1 |
| Xu, TL | 1 |
| Su, J | 1 |
| Li, WG | 1 |
| Ireland, AJ | 1 |
| Ellis, P | 1 |
| Jordan, A | 1 |
| Bradley, R | 1 |
| Ewings, P | 1 |
| Atack, NE | 1 |
| Griffiths, H | 1 |
| House, K | 1 |
| Moore, MB | 1 |
| Deacon, S | 1 |
| Wenger, N | 1 |
| Worth, V | 1 |
| Scaysbrook, E | 1 |
| Williams, JC | 1 |
| Sandy, JR | 1 |
| Minor, V | 1 |
| Marris, CK | 1 |
| McGorray, SP | 1 |
| Yezierski, R | 1 |
| Fillingim, R | 1 |
| Logan, H | 1 |
| Wheeler, TT | 1 |
| Rudin, A | 1 |
| Eriksson, L | 1 |
| Liedholm, R | 1 |
| List, T | 1 |
| Werner, MU | 1 |
| Guerrero, JM | 1 |
| Castaño, PM | 1 |
| Schmidt, EO | 1 |
| Rosario, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Auriculotherapy as an Adjunct for Pain Management During Medication Abortion: a Randomized, Double-blinded, Three-arm Trial[NCT03900728] | 138 participants (Actual) | Interventional | 2019-04-01 | Completed | |||
| Auriculotherapy as an Adjunct for Pain Management During First Trimester Vacuum Aspiration Abortion: a Randomized, Double-blinded, Three Arm Trial[NCT03896022] | 177 participants (Actual) | Interventional | 2019-03-28 | Completed | |||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain of Initial Orthodontic Wire Insertion: a Randomized Controlled Trial[NCT04059172] | Early Phase 1 | 375 participants (Anticipated) | Interventional | 2019-12-10 | Recruiting | ||
| Music to Reduce Patient Reported Pain During Intrauterine Device (IUD) Placement in the Office[NCT05068245] | 96 participants (Actual) | Interventional | 2020-08-28 | Completed | |||
| Music as an Auxiliary Analgesic and Anxiolytic During First Trimester Abortion[NCT01013363] | 106 participants (Actual) | Interventional | 2009-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Self-assessed maximum anxiety reported using a 0-100 mm visual analog scale, where 100 signifies maximum anxiety. (NCT03900728)
Timeframe: Auriculotherapy is applied on the day of mifepristone. Participants take misoprostol 1-3 days later. Anxiety scores are recorded following misoprostol at 8pm x 4 days (selecting the highest of 4 for analysis).
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy With Needles (Acupuncture) + Usual Care | 45 |
| Auriculotherapy With Gold Beads (Acupressure) + Usual Care | 10 |
| Placebo Group + Usual Care | 30 |
Self-assessed maximum pain reported using a 0-100 mm visual analog scale (VAS), where 100 signifies maximum pain. (NCT03900728)
Timeframe: Auriculotherapy is applied on the day of mifepristone. Participants take misoprostol 1-3 days later. Pain scores are recorded following misoprostol at 8pm x 4 days (selecting the highest of the 4 for analysis).
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy With Needles (Acupuncture) + Usual Care | 75 |
| Auriculotherapy With Gold Beads (Acupressure) + Usual Care | 60 |
| Placebo Group + Usual Care | 55 |
Self-assessed maximum anxiety reported using a 0-100 mm visual analog scale, where 100 signifies maximum anxiety. To measure anxiety during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupressure With Gold Beads | 26 |
| Auriculotherapy - Acupuncture With Pyonex Needles | 28 |
| Placebo Group | 21 |
Self-assessed maximum pain reported using a 0-100mm visual analog scale, where 100 signifies maximum pain. To measure pain experienced during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupressure With Gold Beads | 50 |
| Placebo Group | 47.5 |
Self-assessed maximum pain reported using a 0-100mm visual analog scale, where 100 signifies maximum pain. To measure pain experienced during aspiration abortion. (NCT03896022)
Timeframe: Immediately following the aspiration abortion procedure (approximately 10 minutes)
| Intervention | score on a scale (Median) |
|---|---|
| Auriculotherapy - Acupuncture With Pyonex Needles | 55 |
| Placebo Group | 47.5 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
1 review available for ibuprofen and Anxiety
| Article | Year |
|---|---|
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug | 2009 |
4 trials available for ibuprofen and Anxiety
| Article | Year |
|---|---|
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Auricular acupuncture as an adjunct for pain management during first trimester abortion: a randomized, double-blinded, three arm trial.
Topics: Abortion, Induced; Acupuncture, Ear; Adult; Anesthesia, Obstetrical; Anxiety; Double-Blind Method; F | 2019 |
Chewing gum vs. ibuprofen in the management of orthodontic pain, a multi-centre randomised controlled trial - the effect of anxiety.
Topics: Adolescent; Anxiety; Chewing Gum; Child; Humans; Ibuprofen; Pain; Societies, Dental | 2017 |
Effects of preoperative ibuprofen on pain after separator placement.
Topics: Adolescent; Adult; Affect; Analgesics, Non-Narcotic; Anxiety; Attitude to Health; Dental Occlusion; | 2009 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
Music as an auxiliary analgesic during first trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia | 2012 |
5 other studies available for ibuprofen and Anxiety
| Article | Year |
|---|---|
The effects of Ibuprofen and 1, 8- cineol on anxiety and spatial memory in hyperammonemic rats.
Topics: Animals; Anxiety; Eucalyptol; Hippocampus; Hyperammonemia; Ibuprofen; Oxidative Stress; Rats; Rats, | 2023 |
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex; | 2023 |
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex; | 2023 |
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex; | 2023 |
Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice.
Topics: Animals; Anxiety; Anxiety Disorders; Chronic Pain; Ibuprofen; Inflammation; Mice; Prefrontal Cortex; | 2023 |
The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice.
Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Animal; | 2021 |
Temporal dynamics of anxiety phenotypes in a dental pulp injury model.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anxiety; Behavior, Animal; Dental Pulp; Disease Model | 2015 |
Prediction of postoperative pain after mandibular third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Attitude; Depression; Eating; Female; Follo | 2010 |