Page last updated: 2024-10-28

ibuprofen and Alloxan Diabetes

ibuprofen has been researched along with Alloxan Diabetes in 15 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
" Both ibuprofen and L-arginine exert antiallodynic effects on chronic constriction injury (CCI)-induced cold allodynia."7.83Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy. ( Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M, 2016)
"To investigate the effects of ibuprofen on cardiac fibrosis in a rat model of type 1 diabetes."7.81Ibuprofen attenuates cardiac fibrosis in streptozotocin-induced diabetic rats. ( Chen, B; Guo, H; Hu, G; Liu, Y; Lu, Q; Qiao, W; Sun, H; Wang, C; Yan, C; Yin, X; Zhang, F, 2015)
"Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract."7.68Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992)
" Both ibuprofen and L-arginine exert antiallodynic effects on chronic constriction injury (CCI)-induced cold allodynia."3.83Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy. ( Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M, 2016)
"To investigate the effects of ibuprofen on cardiac fibrosis in a rat model of type 1 diabetes."3.81Ibuprofen attenuates cardiac fibrosis in streptozotocin-induced diabetic rats. ( Chen, B; Guo, H; Hu, G; Liu, Y; Lu, Q; Qiao, W; Sun, H; Wang, C; Yan, C; Yin, X; Zhang, F, 2015)
"Evidence from epidemiological, in vitro and animal studies has accumulated to support the idea that aspirin, ibuprofen and paracetamol protect against cataract."3.68Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen. ( Blakytny, R; Harding, JJ, 1992)
"Ibuprofen (IBU) was chemically coupled with diosgenin either directly or through amino acid esters linkers."1.39Synthesis of diosgenin-ibuprofen derivatives and their activities against insulin-dependent diabetes mellitus. ( Chen, Q; Du, D; Guo, X; He, S; He, Y; Huang, B; Huang, W; Wang, Y; Xin, G; Xing, Z; Zhang, R; Zhao, H, 2013)
"Hydronephrosis was induced to permit direct visualization of renal microvessels."1.29Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat. ( Epstein, M; Forster, HG; Hohman, TC; Takenaka, T; ter Wee, PM, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's5 (33.33)18.2507
2000's0 (0.00)29.6817
2010's7 (46.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Guo, C1
Cao, M1
Diao, N1
Wang, W1
Geng, H1
Su, Y1
Sun, T1
Lu, X1
Kong, M1
Chen, D1
Xin, G1
Wang, Y1
Guo, X1
Huang, B1
Du, D1
He, S1
Zhang, R1
Xing, Z1
Zhao, H1
Chen, Q1
Huang, W1
He, Y1
Yada, T1
Shimokawa, H1
Hiramatsu, O1
Goto, M1
Ogasawara, Y1
Kajiya, F1
Qiao, W1
Wang, C1
Chen, B1
Zhang, F2
Liu, Y1
Lu, Q2
Guo, H2
Yan, C1
Sun, H1
Hu, G1
Yin, X1
da Silva Dias, IC1
Carabelli, B1
Ishii, DK1
de Morais, H1
de Carvalho, MC1
Rizzo de Souza, LE1
Zanata, SM1
Brandão, ML1
Cunha, TM1
Ferraz, AC1
Cunha, JM1
Zanoveli, JM1
Liu, YW1
Zhu, X1
Cheng, YQ1
Yin, XX1
El-Lithy, GM1
El-Bakly, WM1
Matboli, M1
Abd-Alkhalek, HA1
Masoud, SI1
Hamza, M1
Nasrallah, R1
Robertson, SJ1
Karsh, J1
Hébert, RL1
Roth, DM2
Reibel, DK2
Lefer, AM2
Lefer, BL1
Oian, X1
Hall, SD1
Forster, HG1
ter Wee, PM1
Takenaka, T1
Hohman, TC1
Epstein, M2
Koltai, MZ1
Hadházy, P1
Pósa, I1
Kocsis, E1
Winkler, G1
Rösen, P1
Pogátsa, G1
Hayashi, K1
Loutzenhiser, R1
Forster, H1
Blakytny, R1
Harding, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Acetylsalicylic Acid Administered in Patients With Type 2 Diabetes Mellitus and Its Effect on the Antioxidant Enzyme System[NCT03341117]Phase 321 participants (Actual)Interventional2014-12-02Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

15 other studies available for ibuprofen and Alloxan Diabetes

ArticleYear
Novel pH-responsive E-selectin targeting natural polysaccharides hybrid micelles for diabetic nephropathy.
    Nanomedicine : nanotechnology, biology, and medicine, 2023, Volume: 52

    Topics: Angelica sinensis; Animals; Astragalus Plant; Diabetes Mellitus, Experimental; Diabetic Neuropathies

2023
Synthesis of diosgenin-ibuprofen derivatives and their activities against insulin-dependent diabetes mellitus.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:5

    Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diosgenin; Hypoglyce

2013
Role of endogenous hydrogen peroxide during angiotensin type 1 receptor blockers administration in pacing-induced metabolic coronary vasodilatation in dogs in vivo.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2013, Volume: 2013

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Alloxan; Angiotensin II Type 1 Receptor Blockers; Animals; Biological F

2013
Ibuprofen attenuates cardiac fibrosis in streptozotocin-induced diabetic rats.
    Cardiology, 2015, Volume: 131, Issue:2

    Topics: Angiotensin-Converting Enzyme 2; Animals; Cardiotonic Agents; Diabetes Mellitus, Experimental; Diabe

2015
Indoleamine-2,3-Dioxygenase/Kynurenine Pathway as a Potential Pharmacological Target to Treat Depression Associated with Diabetes.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Blood Glucose; Cytokines; Depression; Diabetes Mel

2016
Ibuprofen attenuates nephropathy in streptozotocin‑induced diabetic rats.
    Molecular medicine reports, 2016, Volume: 13, Issue:6

    Topics: Animals; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glutathione; Ibu

2016
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
    Translational research : the journal of laboratory and clinical medicine, 2016, Volume: 177

    Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; D

2016
Celecoxib modifies glomerular basement membrane, mesangium and podocytes in OVE26 mice, but ibuprofen is more detrimental.
    Clinical science (London, England : 1979), 2013, Volume: 124, Issue:11

    Topics: Albumins; Animals; Blood Glucose; Blood Pressure; Celecoxib; Creatinine; Cyclin-Dependent Kinase Inh

2013
Altered coronary vascular responsiveness to leukotrienes in alloxan-diabetic rats.
    Circulation research, 1984, Volume: 54, Issue:4

    Topics: Aging; Animals; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Ibuprofen; Le

1984
Hyperreactivity of coronary vasculature in platelet-perfused hearts from diabetic rats.
    The American journal of physiology, 1983, Volume: 245, Issue:4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cats; Coronary Circulation; Diabetes

1983
Enantioselective effects of experimental diabetes mellitus on the metabolism of ibuprofen.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Cytochrome P-450 Enzyme System;

1995
Impairment of afferent arteriolar myogenic responsiveness in the galactose-fed rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1994, Volume: 206, Issue:4

    Topics: Animals; Arterioles; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Die

1994
Characteristics of coronary endothelial dysfunction in experimental diabetes.
    Cardiovascular research, 1997, Volume: 34, Issue:1

    Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase

1997
Impaired myogenic responsiveness of the afferent arteriole in streptozotocin-induced diabetic rats: role of eicosanoid derangements.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:11

    Topics: Acetylcholine; Animals; Arterioles; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephro

1992
Prevention of cataract in diabetic rats by aspirin, paracetamol (acetaminophen) and ibuprofen.
    Experimental eye research, 1992, Volume: 54, Issue:4

    Topics: Acetaminophen; Animals; Aspirin; Blood Glucose; Cataract; Diabetes Mellitus, Experimental; Female; G

1992