ibuprofen has been researched along with Aging in 33 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was undertaken to determine whether 400 mg of prophylactic ibuprofen can alleviate pain from insertion of an intrauterine device (IUD) and to measure level of pain with improved techniques." | 9.12 | Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen. ( Chen, PL; Croxatto, H; Hubacher, D; Lillo, S; Reyes, V; Zepeda, A, 2006) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 7.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " This study was designed to determine effects of an anti-inflammatory drug, ibuprofen, on cognitive function and NMDA receptor expression across aging." | 7.85 | Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging. ( Bermudez, M; Elias, V; Ho, E; Magnusson, KR; Márquez Loza, A; Wong, CP, 2017) |
| "To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations." | 7.77 | Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011) |
| "Ibuprofen protected the increase of myo-inositol at six months of age in the hippocampus, but had no effect at 17-23 months of age (a time when Aβ is extracellular)." | 5.40 | The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer's disease mouse model using magnetic resonance spectroscopy and imaging. ( Aytan, N; Carreras, I; Choi, JK; Dedeoglu, A; Jenkins, BG; Jenkins-Sahlin, E, 2014) |
| "This study was undertaken to determine whether 400 mg of prophylactic ibuprofen can alleviate pain from insertion of an intrauterine device (IUD) and to measure level of pain with improved techniques." | 5.12 | Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen. ( Chen, PL; Croxatto, H; Hubacher, D; Lillo, S; Reyes, V; Zepeda, A, 2006) |
| "Nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesic drugs, such as acetaminophen (APAP), are frequently taken during pregnancy, even in combination." | 3.91 | In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice. ( Boizet-Bonhoure, B; Brun, C; de Massy, B; Déjardin, S; Ghettas, A; Keime, C; Marchive, C; Nguyen, AL; Ollivier, M; Philibert, P; Poulat, F; Pruvost, A; Rossitto, M, 2019) |
| " This study was designed to determine effects of an anti-inflammatory drug, ibuprofen, on cognitive function and NMDA receptor expression across aging." | 3.85 | Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging. ( Bermudez, M; Elias, V; Ho, E; Magnusson, KR; Márquez Loza, A; Wong, CP, 2017) |
| "To document trends and covariates of creatinemia (Scr) in extremely low birth weight (ELBW, < 1,000 g) neonates, maternal characteristics [betamethasone, premature preterm rupture of membranes (PPROM), pre-eclampsia, maternal Scr], characteristics at delivery [gestational age (GA), birth weight (BW), small for GA (SGA), Apgar, intubation] and during neonatal stay [ventilation, oxygen, parenteral nutrition, ibuprofen, steroids, intraventricular hemorrhage, retinopathy of prematurity (ROP), phototherapy] were linked with Scr observations." | 3.77 | Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates. ( Allegaert, K; George, I; Levtchenko, E; Mekahli, D; Rayyan, M, 2011) |
| "Ibuprofen protected the increase of myo-inositol at six months of age in the hippocampus, but had no effect at 17-23 months of age (a time when Aβ is extracellular)." | 1.40 | The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer's disease mouse model using magnetic resonance spectroscopy and imaging. ( Aytan, N; Carreras, I; Choi, JK; Dedeoglu, A; Jenkins, BG; Jenkins-Sahlin, E, 2014) |
| "Ibuprofen-treated APP23 mice performed significantly better than their sham-treated counterparts and almost attained the same level of performance as control animals on a complex visual-spatial learning task." | 1.36 | Ibuprofen modifies cognitive disease progression in an Alzheimer's mouse model. ( Coen, K; De Deyn, PP; Van Dam, D, 2010) |
| "Recently, low grade inflammation has been suspected to be one of the factors responsible for the decreased sensitivity of muscle protein metabolism to food intake." | 1.35 | Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats. ( Averous, J; Bos, C; Combaret, L; Dardevet, D; Magne, H; Peyron, MA; Rieu, I; Savary-Auzeloux, I, 2009) |
| "Ibuprofen did not inhibit the action of furosemide to improve medullary pO2 in younger subjects." | 1.31 | Effects of furosemide on medullary oxygenation in younger and older subjects. ( Epstein, FH; Prasad, P, 2000) |
| "Ibuprofen treatment increased choroidal PGF2alpha vasoconstrictor effects, IP3 production, and receptors, but did not modify response to U-46619." | 1.30 | Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs. ( Abran, D; Chemtob, S; Varma, DR, 1997) |
| "Ibuprofen is an over-the-counter nonsteroidal anti-inflammatory drug with a low incidence of severe adverse reactions." | 1.29 | Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly. ( Castillo, M; Dooley, MA; Lam, YW; Smith, PC; Stahl, E, 1995) |
| "6 hour-1, corresponding to a half-life of drug in the effect compartment of 1." | 1.28 | Effect of age on ibuprofen pharmacokinetics and antipyretic response. ( Kauffman, RE; Nelson, MV, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (15.15) | 18.7374 |
| 1990's | 10 (30.30) | 18.2507 |
| 2000's | 9 (27.27) | 29.6817 |
| 2010's | 8 (24.24) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Rossitto, M | 1 |
| Ollivier, M | 1 |
| Déjardin, S | 1 |
| Pruvost, A | 1 |
| Brun, C | 1 |
| Marchive, C | 1 |
| Nguyen, AL | 1 |
| Ghettas, A | 1 |
| Keime, C | 1 |
| de Massy, B | 1 |
| Poulat, F | 1 |
| Philibert, P | 1 |
| Boizet-Bonhoure, B | 1 |
| Harder, OE | 1 |
| Martinez, M | 1 |
| Niewiesk, S | 1 |
| Canan, CH | 1 |
| Gokhale, NS | 1 |
| Carruthers, B | 1 |
| Lafuse, WP | 1 |
| Schlesinger, LS | 1 |
| Torrelles, JB | 1 |
| Turner, J | 1 |
| Choi, JK | 1 |
| Carreras, I | 1 |
| Aytan, N | 1 |
| Jenkins-Sahlin, E | 1 |
| Dedeoglu, A | 1 |
| Jenkins, BG | 1 |
| Márquez Loza, A | 1 |
| Elias, V | 1 |
| Wong, CP | 1 |
| Ho, E | 1 |
| Bermudez, M | 1 |
| Magnusson, KR | 1 |
| Van Dam, D | 1 |
| Coen, K | 1 |
| De Deyn, PP | 1 |
| Rieu, I | 1 |
| Magne, H | 1 |
| Savary-Auzeloux, I | 1 |
| Averous, J | 1 |
| Bos, C | 1 |
| Peyron, MA | 1 |
| Combaret, L | 1 |
| Dardevet, D | 1 |
| George, I | 1 |
| Mekahli, D | 1 |
| Rayyan, M | 1 |
| Levtchenko, E | 1 |
| Allegaert, K | 1 |
| Costelloe, C | 1 |
| Montgomery, AA | 1 |
| Redmond, NM | 1 |
| Fletcher, M | 1 |
| Hollinghurst, S | 1 |
| Peters, TJ | 1 |
| Hay, AD | 1 |
| Knight, EM | 1 |
| Brown, TM | 1 |
| Gümüsgöz, S | 1 |
| Smith, JC | 1 |
| Waters, EJ | 1 |
| Allan, SM | 1 |
| Lawrence, CB | 1 |
| Bessler, H | 1 |
| Ziyada, S | 1 |
| Bergman, M | 1 |
| Punsky, I | 1 |
| Sirota, L | 1 |
| Kang, JH | 1 |
| Grodstein, F | 1 |
| Tan, SC | 1 |
| Patel, BK | 1 |
| Jackson, SH | 1 |
| Swift, CG | 1 |
| Hutt, AJ | 1 |
| Hubacher, D | 1 |
| Reyes, V | 1 |
| Lillo, S | 1 |
| Zepeda, A | 1 |
| Chen, PL | 1 |
| Croxatto, H | 1 |
| Roth, DM | 1 |
| Reibel, DK | 1 |
| Lefer, AM | 1 |
| Castillo, M | 1 |
| Lam, YW | 1 |
| Dooley, MA | 1 |
| Stahl, E | 1 |
| Smith, PC | 1 |
| Malik, NS | 1 |
| Meek, KM | 1 |
| Abran, D | 1 |
| Varma, DR | 2 |
| Chemtob, S | 2 |
| Mulkerrin, EC | 1 |
| Clark, BA | 1 |
| Epstein, FH | 3 |
| Rainsford, KD | 1 |
| Roberts, SC | 1 |
| Brown, S | 1 |
| Prasad, PV | 1 |
| Fowler, CJ | 1 |
| Janson, U | 1 |
| Johnson, RM | 1 |
| Wahlström, G | 1 |
| Stenström, A | 1 |
| Norström, K | 1 |
| Tiger, G | 1 |
| Farquhar, WB | 1 |
| Kenney, WL | 1 |
| Farquhar, W | 1 |
| Kenney, L | 1 |
| Dumont, I | 1 |
| Hardy, P | 1 |
| Peri, KG | 1 |
| Hou, X | 1 |
| Molotchnikoff, S | 1 |
| Prasad, P | 1 |
| Strain, WD | 1 |
| Lye, M | 1 |
| McKenzie, LS | 1 |
| Horsburgh, BA | 1 |
| Ghosh, P | 1 |
| Taylor, TK | 1 |
| Kauffman, RE | 1 |
| Nelson, MV | 1 |
| Kendall, MJ | 1 |
| Jubb, R | 1 |
| Bird, HA | 1 |
| le Gallez, P | 1 |
| Hill, J | 1 |
| Taggart, AJ | 1 |
| Rau, R | 1 |
| Hellerstein, MK | 1 |
| Jackson, EK | 1 |
| Lauter, SA | 1 |
| Reece, D | 1 |
| Avioli, LV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prematurity as Predictor of Children's Cardiovascular-renal Health (PREMATCH)[NCT02147457] | 180 participants (Actual) | Observational | 2014-10-31 | Completed | |||
| Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience[NCT02312726] | 135 participants (Actual) | Observational | 2013-11-30 | Completed | |||
| Pain Control for Intrauterine Device Placement: A Randomized Controlled Trial of Paracervical Block[NCT02219308] | 67 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Randomized Controlled Trial of Cervical Lidocaine for Intrauterine Device Insertion Pain[NCT01411995] | 200 participants (Actual) | Interventional | 2011-08-31 | Completed | |||
| Study of Pain Control With Hormonal IUS Insertion (SOPHI Study)[NCT02352714] | Phase 4 | 98 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Effect of Adding Vaginal Isosorbide Mononitrate to Misoprostol Prior to Intrauterine Device Insertion in Women Delivered Only by Elective Cesarean Section: a Randomized Double-blind Controlled Clinical Trial[NCT03587077] | 113 participants (Anticipated) | Interventional | 2018-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A semi-structured interview guide(available in both English and Spanish) which was developed in consultation with an expert in qualitative methodology at the UNM Clinical & Translational Science Center (CTSC), and UNMH family planning experts, will be administered to all participants. The interview will incorporate the following domains of women's perceptions of the postplacental IUD insertion experience: decisional influence, experience during the procedure, decisional regret, prior knowledge/ awareness of the method and postpartum contraception in general. The interview will conclude with an overall patient satisfaction score measured on a five-point Likert scale: 1 = very dissatisfied, 2 = somewhat dissatisfied, 3 = neutral, 4 = somewhat satisfied, 5 = very satisfied. (NCT02312726)
Timeframe: Within 24-48 hours after vaginal delivery, prior to hospital discharge
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Very Satified | Satisfied | Neutral | Dissatisfied | Very Dissatisfied | |
| Epidural Group | 12 | 0 | 0 | 0 | 0 |
| Non Epidural Group | 7 | 2 | 0 | 0 | 0 |
This is a 4-item ordinal pain scale which has been used for pain level assessment. When prompted, patients will be asked to indicate which level of pain most accurately represents their pain level; 0 = No pain, 1 = Mild pain, 2 = Moderate pain, 3 = Severe pain. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery. Women who undergo a postpartum interview will be asked to perform a recal VRS pain assessment
| Intervention | participants (Number) | |||||
|---|---|---|---|---|---|---|
| No Pain or Mild Pain before IUD placement | No Pain or Mild Pain during IUD placement | No Pain or Mild Pain at recall | Moderate Pain or Severe Pain before IUD placement | Moderate Pain or Severe Pain during IUD placement | Moderate Pain or Severe Pain at recall | |
| Epidural Group | 34 | 32 | 12 | 2 | 4 | 0 |
| Non Epidural Group | 15 | 16 | 6 | 15 | 14 | 3 |
This is a validated instrument used extensively in the assessment of acute pain. When prompted, patients will be asked to mark the continuous 100 mm VAS line at the point which most accurately represents their pain level; 0 = no pain, 100 = pain as bad as it could be. (NCT02312726)
Timeframe: Immediately prior to and within 5 minutes after IUD insertion following vaginal delivery; women who undergo a postpartum interview will be asked to perform a recall VAS pain assessment
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Pre-insertion | Procedure | Recall | |
| Epidural Group | 10.6 | 10.9 | 5.4 |
| Non Epidural Group | 35.3 | 41.4 | 28.6 |
The provider who inserts the IUD will be asked to complete a 4-item Likert scale rating perceived difficultly of insertion: 1 = easy; 2 = somewhat easy; 3 = somewhat difficult, 4 = difficult. (NCT02312726)
Timeframe: Within 5 minutes following postpartum IUD insertion
| Intervention | participants (Number) | ||||
|---|---|---|---|---|---|
| Easy | Somewhat easy | Somewhat difficult | Difficult | Unanswered | |
| Epidural Group | 19 | 16 | 3 | 0 | 0 |
| Non Epidural Group | 15 | 11 | 3 | 0 | 1 |
Distance (mm) from the left of the 100-mm visual analog scale (reflecting magnitude of pain) recorded at time of IUD Placement. Scale range is from 0mm (no pain) to 100mm (worst pain possible). A lower score (less pain) is considered a better outcome. (NCT02219308)
Timeframe: Moment of IUD insertion
| Intervention | mm (Median) |
|---|---|
| No Paracervical Block (Sham PCB) | 54 |
| Paracervical Block (PCB) | 33 |
Distance (mm) from the left of the 100-mm visual analog scale of pain at various time points. Scale range is 0mm (no pain) to 100mm (worst pain possible). Lower scores are considered better outcomes. (NCT02219308)
Timeframe: Anticipation of procedure through 5 minutes after IUD placement
| Intervention | mm (Median) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Anticipated Pain | Baseline Pain | Speculum Insertion | Capped Needle or PCB | Tenaculum placement | Uterine Sounding | IUD placement | 5 mins after IUD placement | Overall pain | |
| No Paracervical Block (Sham PCB) | 51 | 0 | 6 | 8 | 10 | 47 | 54 | 27 | 51 |
| Paracervical Block (PCB) | 58 | 0 | 10 | 30 | 15 | 30 | 33 | 12 | 30 |
"Using a visual analog scale, women will report their level of pain pre-procedure, after tenaculum placement, and post-procedure (following IUD insertion).The entirety of the procedure should last no more than 5-10 minutes. The pain score is assessed at the 3 timepoints within that 10 minute window. No additional followup is required.~Range: 0-10 (0= no pain, 10=worst pain)" (NCT01411995)
Timeframe: Immediately following IUD insertion
| Intervention | units on visual analog scale (Median) |
|---|---|
| 2% Lidocaine Gel | 5 |
| Water Based Lubricant | 6 |
1 review available for ibuprofen and Aging
| Article | Year |
|---|---|
Ibuprofen and paracetamol: relative safety in non-prescription dosages.
Topics: Acetaminophen; Aged; Aging; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents | 1997 |
5 trials available for ibuprofen and Aging
| Article | Year |
|---|---|
Medicine dosing by weight in the home: can parents accurately weigh preschool children? A method comparison study.
Topics: Acetaminophen; Aging; Anthropometry; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Body Wei | 2011 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Pain from copper intrauterine device insertion: randomized trial of prophylactic ibuprofen.
Topics: Adult; Aging; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen; Intrauterine | 2006 |
Increased salt retention and hypertension from non-steroidal agents in the elderly.
Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hypertension; Ibuprofen | 1997 |
Age and renal prostaglandin inhibition during exercise and heat stress.
Topics: Adult; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Double-Blind Method; Exer | 1999 |
Renal effects of ibuprofen during sodium restriction in the aged.
Topics: Adult; Age Factors; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Cross-Over Stu | 2000 |
27 other studies available for ibuprofen and Aging
| Article | Year |
|---|---|
In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice.
Topics: Acetaminophen; Aging; Animals; Animals, Newborn; Cell Proliferation; Female; Fertility; Forkhead Box | 2019 |
Nonsteroidal anti-inflammatory drugs restore immune function to respiratory syncytial virus in geriatric cotton rats (Sigmodon hispidus).
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Ibuprofen; Immunity, Humoral; Male; | 2021 |
Characterization of lung inflammation and its impact on macrophage function in aging.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cytokines; Female; Gene Ex | 2014 |
The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer's disease mouse model using magnetic resonance spectroscopy and imaging.
Topics: Aging; Alzheimer Disease; Amygdala; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain Chemistr | 2014 |
Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging.
Topics: Aging; Alternative Splicing; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Co | 2017 |
Ibuprofen modifies cognitive disease progression in an Alzheimer's mouse model.
Topics: Aging; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cognition Disorders; Dis | 2010 |
Reduction of low grade inflammation restores blunting of postprandial muscle anabolism and limits sarcopenia in old rats.
Topics: Aging; Animals; Anti-Inflammatory Agents, Non-Steroidal; Eating; Ibuprofen; Inflammation; Metabolism | 2009 |
Postnatal trends in creatinemia and its covariates in extremely low birth weight (ELBW) neonates.
Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Apgar Score; Birth Weight; Cohort Studies; Cr | 2011 |
Age-related changes in core body temperature and activity in triple-transgenic Alzheimer's disease (3xTgAD) mice.
Topics: Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Ste | 2013 |
Indomethacin and ibuprofen effect on IL-1ra production by mononuclear cells of preterm newborns and adults.
Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Indomethacin; Infant, Newb | 2002 |
Regular use of nonsteroidal anti-inflammatory drugs and cognitive function in aging women.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Aspir | 2003 |
Influence of age on the enantiomeric disposition of ibuprofen in healthy volunteers.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; S | 2003 |
Altered coronary vascular responsiveness to leukotrienes in alloxan-diabetic rats.
Topics: Aging; Animals; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Ibuprofen; Le | 1984 |
Disposition and covalent binding of ibuprofen and its acyl glucuronide in the elderly.
Topics: Administration, Oral; Aged; Aging; Glucuronates; Humans; Ibuprofen | 1995 |
Vitamins and analgesics in the prevention of collagen ageing.
Topics: Acetaminophen; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Ascorbic Acid; Aspirin; Cellula | 1996 |
Regulation of prostanoid vasomotor effects and receptors in choroidal vessels of newborn pigs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Animals, Newborn | 1997 |
Changes in renal medullary pO2 during water diuresis as evaluated by blood oxygenation level-dependent magnetic resonance imaging: effects of aging and cyclooxygenase inhibition.
Topics: Adult; Aged; Aging; Cyclooxygenase Inhibitors; Dinoprostone; Diuresis; Female; Humans; Ibuprofen; Ki | 1999 |
Inhibition of anandamide hydrolysis by the enantiomers of ibuprofen, ketorolac, and flurbiprofen.
Topics: Aging; Animals; Arachidonic Acids; Brain; Cell Extracts; Cell Survival; Dose-Response Relationship, | 1999 |
Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid.
Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Choroid; Cyclooxygenase Inhibitors; Eye; Homeostas | 2000 |
Effects of furosemide on medullary oxygenation in younger and older subjects.
Topics: Adult; Aging; Female; Furosemide; Humans; Ibuprofen; Kidney Medulla; Magnetic Resonance Imaging; Mal | 2000 |
Chronic pain, bereavement and overdose in a depressed elderly woman.
Topics: Acetaminophen; Aged; Aged, 80 and over; Aging; Aortic Aneurysm, Thoracic; Aspirin; Back Pain; Bereav | 2002 |
Effect of anti-inflammatory drugs on sulphated glycosaminoglycan synthesis in aged human articular cartilage.
Topics: Aged; Aging; Anti-Inflammatory Agents; Cartilage, Articular; Depression, Chemical; Flurbiprofen; Gly | 1976 |
Effect of age on ibuprofen pharmacokinetics and antipyretic response.
Topics: Acute Disease; Aging; Axilla; Body Temperature; Child; Child, Preschool; Drug Evaluation; Female; Fe | 1992 |
A pharmacokinetic comparison of ibuprofen sustained-release tablets given to young and elderly patients.
Topics: Adult; Aged; Aged, 80 and over; Aging; Delayed-Action Preparations; Female; Humans; Ibuprofen; Male; | 1990 |
Aging, diet, and the acute-phase response to inflammation.
Topics: Acute-Phase Reaction; Aging; Animals; Anorexia; Brain; Carbohydrate Metabolism; Citrates; Diet; Drug | 1989 |
Defective modulation of noradrenergic neurotransmission by endogenous prostaglandins in aging spontaneously hypertensive rats.
Topics: Aging; Angiotensin II; Animals; Blood Pressure; Ibuprofen; Indomethacin; Male; Norepinephrine; Rats; | 1989 |
Polymyalgia rheumatica.
Topics: Aged; Aging; Blood Sedimentation; Female; Humans; Ibuprofen; Middle Aged; Polymyalgia Rheumatica; Pr | 1985 |