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ibuprofen and Age-Related Memory Disorders

ibuprofen has been researched along with Age-Related Memory Disorders in 15 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors."8.02The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021)
"The hepatic encephalopathy was induced by bile-duct ligation (BDL), and the animals received first dose of MINO and/or IBU 15 days later and then every day until the 28 day."5.51Inhibition of inflammation is not enough for recovery of cognitive impairment in hepatic encephalopathy: Effects of minocycline and ibuprofen. ( Firouzjaei, MA; Haghani, M; Mohammadi, F; Mohammadian, F; Shabani, M; Shid Moosavi, SM, 2019)
"The findings showed that ibuprofen significantly improved mice's performance in the passive avoidance test and reduced anxiety- and depressive-like behaviors."4.02The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice. ( Baghcheghi, Y; Hosseini, M; Salmani, H; Samadi-Noshahr, Z, 2021)
"Ibuprofen (30 mg/kg) was given twice daily to CIA rats for two weeks starting from Day 18 following the first immunization."1.72Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathways. ( Chou, CH; Kung, FL; Lin, CJ; Wang, TH; Wu, KC; Yang, CR; Zhang, NY, 2022)
"The hepatic encephalopathy was induced by bile-duct ligation (BDL), and the animals received first dose of MINO and/or IBU 15 days later and then every day until the 28 day."1.51Inhibition of inflammation is not enough for recovery of cognitive impairment in hepatic encephalopathy: Effects of minocycline and ibuprofen. ( Firouzjaei, MA; Haghani, M; Mohammadi, F; Mohammadian, F; Shabani, M; Shid Moosavi, SM, 2019)
"Identifying preventive targets for Alzheimer's disease is a central challenge of modern medicine."1.43Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice. ( Andreasson, KI; Boutaud, O; Brown, H; Chuluun, B; Colas, D; Heller, HC; Khroyan, TV; Ko, N; Liang, X; Manning-Boğ, AB; Mhatre, SD; Milne, GL; Minhas, P; Panchal, M; Priyam, PG; Rassoulpour, A; van der Hart, M; Wang, Q; Woodling, NS; Zagol-Ikapitte, I, 2016)
"Ibuprofen is a widely used nonsteroidal anti-inflammatory drug that reportedly reduces the risk of Alzheimer's disease (AD) development."1.40Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice. ( Dong, Z; Huang, G; Mei, B; Meng, B; Yan, L; Zhang, L, 2014)
"Ibuprofen-treated transgenic mice showed a significant decrease in intraneuronal oligomeric Abeta and hyperphosphorylated tau (AT8) immunoreactivity in the hippocampus."1.35Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. ( Carreras, I; Dedeoglu, A; Hossain, L; Jenkins, BG; Klein, WL; Kowall, NW; LaFerla, FM; McKee, AC; Oddo, S; Ryu, H, 2008)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's11 (73.33)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
Zhang, NY1
Wang, TH1
Chou, CH1
Wu, KC1
Yang, CR1
Kung, FL1
Lin, CJ1
Salmani, H1
Hosseini, M1
Baghcheghi, Y1
Samadi-Noshahr, Z1
Goodfellow, MJ1
Shin, YJ1
Lindquist, DH1
Mohammadian, F1
Firouzjaei, MA1
Haghani, M1
Shabani, M1
Shid Moosavi, SM1
Mohammadi, F1
Dong, Z1
Yan, L1
Huang, G1
Zhang, L1
Mei, B1
Meng, B1
Hashmi, AN1
Yaqinuddin, A1
Ahmed, T1
Meunier, J1
Borjini, N1
Gillis, C1
Villard, V1
Maurice, T1
Raoof, R2
Esmaeili-Mahani, S2
Abbasnejad, M2
Raoof, M2
Sheibani, V1
Kooshki, R1
Amirkhosravi, L2
Rafie, F2
Nourzadeh, M1
Hajializadeh, Z1
Haghani, J1
Woodling, NS1
Colas, D1
Wang, Q2
Minhas, P1
Panchal, M1
Liang, X1
Mhatre, SD1
Brown, H1
Ko, N1
Zagol-Ikapitte, I1
van der Hart, M1
Khroyan, TV1
Chuluun, B1
Priyam, PG1
Milne, GL1
Rassoulpour, A1
Boutaud, O1
Manning-Boğ, AB1
Heller, HC1
Andreasson, KI1
Malkki, H1
Gaur, V1
Kumar, A1
Rai, S1
Kamat, PK1
Nath, C1
Shukla, R1
Kotilinek, LA1
Westerman, MA1
Panizzon, K1
Lim, GP1
Simonyi, A1
Lesne, S1
Falinska, A1
Younkin, LH1
Younkin, SG1
Rowan, M1
Cleary, J1
Wallis, RA1
Sun, GY1
Cole, G1
Frautschy, S1
Anwyl, R1
Ashe, KH1
McKee, AC1
Carreras, I1
Hossain, L1
Ryu, H1
Klein, WL1
Oddo, S1
LaFerla, FM1
Jenkins, BG1
Kowall, NW1
Dedeoglu, A1

Other Studies

15 other studies available for ibuprofen and Age-Related Memory Disorders

ArticleYear
Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathways.
    European journal of pharmacology, 2022, Oct-15, Volume: 933

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Excitatory Amino Acid Transporte

2022
The brain consequences of systemic inflammation were not fully alleviated by ibuprofen treatment in mice.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:1

    Topics: Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anxiety; Behavior, Animal;

2021
Mitigation of postnatal ethanol-induced neuroinflammation ameliorates trace fear memory deficits in juvenile rats.
    Behavioural brain research, 2018, 02-15, Volume: 338

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Conditioning, Psychological; Cytokines; Dis

2018
Inhibition of inflammation is not enough for recovery of cognitive impairment in hepatic encephalopathy: Effects of minocycline and ibuprofen.
    Brain research bulletin, 2019, Volume: 149

    Topics: Animals; Bile Ducts; Blood-Brain Barrier; Cognition; Cognitive Dysfunction; Disease Models, Animal;

2019
Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice.
    Neuroscience, 2014, Jun-13, Volume: 270

    Topics: Age Factors; Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD; Anti

2014
Pharmacological effects of Ibuprofen on learning and memory, muscarinic receptors gene expression and APP isoforms level in pre-frontal cortex of AlCl₃-induced toxicity mouse model.
    The International journal of neuroscience, 2015, Volume: 125, Issue:4

    Topics: Aluminum Chloride; Aluminum Compounds; Amyloid beta-Protein Precursor; Analysis of Variance; Animals

2015
Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative.
    Journal of Alzheimer's disease : JAD, 2015, Volume: 44, Issue:2

    Topics: Adenine; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Anti-Inflammatory Age

2015
Changes in hippocampal orexin 1 receptor expression involved in tooth pain-induced learning and memory impairment in rats.
    Neuropeptides, 2015, Volume: 50

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzoxazoles; Capsaicin; Dental Pulp; Hippocampus;

2015
Noxious Stimulation of the Rat Tooth Pulp May Impair Learning and Memory Through the Induction of Hippocampal Apoptosis.
    Journal of oral & facial pain and headache, 2015,Fall, Volume: 29, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Behavior, A

2015
Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.
    Brain : a journal of neurology, 2016, Volume: 139, Issue:Pt 7

    Topics: Alzheimer Disease; Animals; Behavior, Animal; Cyclooxygenase Inhibitors; Disease Models, Animal; Dow

2016
Alzheimer disease: NSAIDs protect neurons and preserve memory in a mouse model of AD.
    Nature reviews. Neurology, 2016, Volume: 12, Issue:7

    Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Ibuprof

2016
Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury.
    Drug and chemical toxicology, 2012, Volume: 35, Issue:2

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 2 Inhibitors; Glutathione

2012
A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats.
    Journal of neuroimmunology, 2013, Jan-15, Volume: 254, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cytokines; Disease Models, Animal; Dose-Res

2013
Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.
    Brain : a journal of neurology, 2008, Volume: 131, Issue:Pt 3

    Topics: Amyloid beta-Peptides; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibi

2008
Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice.
    Brain research, 2008, May-01, Volume: 1207

    Topics: Adenosine Triphosphatases; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor;

2008