ibuprofen has been researched along with Adjuvant Arthritis in 50 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objectives of this study were (1) to fabricate ibuprofen-loaded porous microspheres (IBU/PMSs), (2) to evaluate the in vitro anti-inflammatory effects of the microspheres using LPS-induced inflammation in cultured synoviocytes, and (3) to evaluate the in vivo effect of the IBU/PMSs on the progression of monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in a rat model." | 7.83 | Ibuprofen-loaded porous microspheres suppressed the progression of monosodium iodoacetate-induced osteoarthritis in a rat model. ( Kim, HJ; Kim, SE; Lee, JY; Park, JW; Park, K; Song, HR; Yun, YP, 2016) |
| "We evaluated the effects of a casein hydrolysate (CH) prepared from Aspergillus oryzae protease on rat adjuvant arthritis, a model of human rheumatoid arthritis." | 7.74 | Effects of a casein hydrolysate prepared from Aspergillus oryzae protease on adjuvant arthritis in rats. ( Abe, C; Hatori, M; Hirano, S; Kuboki, H; Ohki, K; Yang, XP, 2008) |
| " The aim of this study was to investigate the possible relationship between experimental adjuvant arthritis following ibuprofen treatment and morphological alterations of the parotid glands in rats." | 7.72 | Morphological changes of parotid glands following adjuvant arthritis and ibuprofen treatment in rats. ( Mourouzis, C; Saranteas, T; Tesseromatis, C; Tsamouris, M, 2003) |
| " The present study was undertaken to assess markers of inflammation, arthritis and pain in rats with adjuvant arthritis undergoing treatment with ibuprofen cream (Dolgit cream) and placebo." | 7.72 | Quantitative assessment of markers of inflammation, arthritis and pain in rats with adjuvant arthritis following the treatment with ibuprofen cream and placebo. ( Istok, R; Rovenský, J; Stancíková, M; Svík, K, 2003) |
| "The effects of combined single oral treatments with non-steroidal anti-inflammatory drugs (NSAIDs) and the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist dextromethorphan (DM) on arthritic pain were examined in a rat model of adjuvant-induced arthritis." | 7.69 | Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats. ( Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD, 1996) |
| "The effect of prolonged treatment with etodolac (8 mg/kg) on the articular and bone pathology at the tibiotarsal joint associated with adjuvant arthritis in the rat has been studied and compared to the effects produced by treatment with naproxen (8 mg/kg) and ibuprofen (50 mg/kg)." | 7.67 | Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats. ( Klicius, J; Martel, RR; Metcalf, G; Rona, GA, 1984) |
| "Anti-inflammatory effect of ibuprofen was studied on the model of adjuvant arthritis." | 7.67 | Haptoglobin and copper in adjuvant arthritis during the ibuprofen therapy. ( Pawłowski, K, 1984) |
| "Antiinflammatory effect of ibuprofen was studied in the model of adjuvant arthritis in rats." | 7.67 | Proteolytic and beta-glucuronidase activity in adjuvant arthritis during the ibuprofen therapy. ( Pawłowski, K, 1985) |
| "Paw edema was analyzed using a plethysmometer." | 5.48 | Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats. ( Casarin, RCV; Casati, MZ; Cirano, FR; Corrêa, MG; Napimoga, MH; Pimentel, SP; Pires, PR; Ribeiro, FV, 2018) |
| "The objectives of this study were (1) to fabricate ibuprofen-loaded porous microspheres (IBU/PMSs), (2) to evaluate the in vitro anti-inflammatory effects of the microspheres using LPS-induced inflammation in cultured synoviocytes, and (3) to evaluate the in vivo effect of the IBU/PMSs on the progression of monosodium iodoacetate (MIA)-induced osteoarthritis (OA) in a rat model." | 3.83 | Ibuprofen-loaded porous microspheres suppressed the progression of monosodium iodoacetate-induced osteoarthritis in a rat model. ( Kim, HJ; Kim, SE; Lee, JY; Park, JW; Park, K; Song, HR; Yun, YP, 2016) |
| "Phospho-aspirin, phospho-ibuprofen and phospho-sulindac were safer than their parent NSAIDs, were highly effective in rat adjuvant arthritis and inhibited many key mediators in the pathophysiology of RA." | 3.77 | The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats. ( Huang, L; Johnson, F; Komninou, D; Mackenzie, G; Ouyang, N; Rigas, B; Sun, Y; Xie, G, 2011) |
| "We evaluated the effects of a casein hydrolysate (CH) prepared from Aspergillus oryzae protease on rat adjuvant arthritis, a model of human rheumatoid arthritis." | 3.74 | Effects of a casein hydrolysate prepared from Aspergillus oryzae protease on adjuvant arthritis in rats. ( Abe, C; Hatori, M; Hirano, S; Kuboki, H; Ohki, K; Yang, XP, 2008) |
| " The aim of this study was to investigate the possible relationship between experimental adjuvant arthritis following ibuprofen treatment and morphological alterations of the parotid glands in rats." | 3.72 | Morphological changes of parotid glands following adjuvant arthritis and ibuprofen treatment in rats. ( Mourouzis, C; Saranteas, T; Tesseromatis, C; Tsamouris, M, 2003) |
| " The present study was undertaken to assess markers of inflammation, arthritis and pain in rats with adjuvant arthritis undergoing treatment with ibuprofen cream (Dolgit cream) and placebo." | 3.72 | Quantitative assessment of markers of inflammation, arthritis and pain in rats with adjuvant arthritis following the treatment with ibuprofen cream and placebo. ( Istok, R; Rovenský, J; Stancíková, M; Svík, K, 2003) |
| "A series of 2-substituted- and 2,3-disubstituted-4-(4-fluorophenyl)-5-[4-(methylsulfonyl)phenyl]-1H- pyrroles was synthesized and found to be active in the rat adjuvant arthritis model of inflammation." | 3.69 | Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR. ( Galbraith, W; Gans-Brangs, K; Grubb, M; Hewes, WE; Jaffee, B; Kenney, JP; Kerr, J; Wilkerson, WW; Wong, N, 1994) |
| "The effects of combined single oral treatments with non-steroidal anti-inflammatory drugs (NSAIDs) and the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist dextromethorphan (DM) on arthritic pain were examined in a rat model of adjuvant-induced arthritis." | 3.69 | Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats. ( Caruso, FS; Frenk, H; Lu, J; Mao, J; Mayer, DJ; Price, DD, 1996) |
| " The anti-inflammatory potency of NS-398 in rat carrageenin-induced edema was as potent as that of indomethacin and 8 times more potent than diclofenac." | 3.68 | NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993) |
| "Replacement of the carboxyl group of 2-(3-benzoylphenyl)propionic acid (Ketoprofen) with various bulky amines has produced a series of highly active antiinflammatory agents that have reduced intestinal ulcerogenicity and have better therapeutic ratios in the 21-day adjuvant arthritis assay in rats than currently marketed nonsteroidal antiinflammatory drugs." | 3.67 | Bulky amine analogues of ketoprofen: potent antiinflammatory agents. ( Behn, DC; Botton, I; Fellows, CA; Laskowski, SC; Phillips, DK; Schlegel, DC; Speight, PT; Zenitz, BL, 1984) |
| "The effect of prolonged treatment with etodolac (8 mg/kg) on the articular and bone pathology at the tibiotarsal joint associated with adjuvant arthritis in the rat has been studied and compared to the effects produced by treatment with naproxen (8 mg/kg) and ibuprofen (50 mg/kg)." | 3.67 | Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats. ( Klicius, J; Martel, RR; Metcalf, G; Rona, GA, 1984) |
| "Anti-inflammatory effect of ibuprofen was studied on the model of adjuvant arthritis." | 3.67 | Haptoglobin and copper in adjuvant arthritis during the ibuprofen therapy. ( Pawłowski, K, 1984) |
| "Antiinflammatory effect of ibuprofen was studied in the model of adjuvant arthritis in rats." | 3.67 | Proteolytic and beta-glucuronidase activity in adjuvant arthritis during the ibuprofen therapy. ( Pawłowski, K, 1985) |
| "Ibuprofen (30 mg/kg) was given twice daily to CIA rats for two weeks starting from Day 18 following the first immunization." | 1.72 | Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathways. ( Chou, CH; Kung, FL; Lin, CJ; Wang, TH; Wu, KC; Yang, CR; Zhang, NY, 2022) |
| "Paw edema was analyzed using a plethysmometer." | 1.48 | Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats. ( Casarin, RCV; Casati, MZ; Cirano, FR; Corrêa, MG; Napimoga, MH; Pimentel, SP; Pires, PR; Ribeiro, FV, 2018) |
| " After dosing of R-IB, AA had minimal effect on the elimination of R-IB from the perfusate." | 1.46 | Stereoselective hepatic disposition of ibuprofen in the perfused liver of rat with adjuvant-induced arthritis. ( Iwaki, M; Kawase, A; Uraki, M, 2017) |
| "Attenuation of hyperalgesia of inflamed TMJ by NSAIDs might be associated with their role in blocking upregulation of trigeminal ganglionic Nav1." | 1.43 | Non-steroidal Anti-inflammatory Drugs Attenuate Hyperalgesia and Block Upregulation of Trigeminal Ganglionic Sodium Channel 1.7 after Induction of Temporomandibular Joint Inflammation in Rats. ( Bi, RY; Ding, Y; Gan, YH, 2016) |
| "Paw volume, thermal hyperalgesia, mechanical allodynia, joint stiffness and mobility behaviors (score) were measured." | 1.37 | Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat. ( Bijjem, KR; Kaur, S; Sharma, PL, 2011) |
| "Ibuprofen treatment decreased the raised level on day 21 and increased the reduced level on day 35." | 1.32 | Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat. ( Banerjee, M; Puri, A; Shukla, R; Srivastava, VM; Tripathi, LM, 2003) |
| "We investigated whether chemical association of phosphatidylcholine (PC) to ibuprofen enhances the anti-inflammatory/analgesic activity of the nonsteroidal anti-inflammatory drug (NSAID) and whether any change in therapeutic action is due to alterations in drug bioavailability and cyclooxygenase (COX) inhibitory activity." | 1.31 | Phosphatidylcholine association increases the anti-inflammatory and analgesic activity of ibuprofen in acute and chronic rodent models of joint inflammation: relationship to alterations in bioavailability and cyclooxygenase-inhibitory potency. ( Ashraf, AQ; Behbod, F; Darling, R; de Ruijter, WM; Lichtenberger, LM; Romero, JJ; Sanduja, SK, 2001) |
| " AD-1590 and indomethacin at an oral dosage as high as 32 mg/kg did not show any significant inhibitory activity on rat passive cutaneous anaphylaxis, a type-I allergy, although prednisolone and cyproheptadine produced strong inhibition." | 1.27 | [Inhibitory effect of AD-1590, a non-steroidal anti-inflammatory drug, on allergic inflammation in mice and rats]. ( Ishii, K; Kadokawa, T; Motoyoshi, S; Nakamura, H, 1988) |
| " The compounds of most interest, 18 and 28, were further tested in a model of adjuvant-induced arthritis; in this system, both compounds were active when dosed intraperitoneally but failed to produce significant activity when dosed orally at subtoxic doses." | 1.26 | Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues. ( Millonig, RC; Rovnyak, GC; Schwartz, J; Shu, V, 1982) |
| " It was found that compounds with polar substituents at the 2 or 3 position of the ring system are less acutely toxic while maintaining antiinflammatory activity." | 1.26 | Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles. ( Ariyan, ZS; Fogt, SW; Heilman, RD; Matthews, RJ; Powers, LJ; Rippin, DJ, 1981) |
| "Butibufen was within the potency range of ibuprofen as an antipyretic and analgesic agent and greater than that of acetylsalicylic acid." | 1.26 | Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent. ( Aparicio, L, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (38.00) | 18.7374 |
| 1990's | 8 (16.00) | 18.2507 |
| 2000's | 9 (18.00) | 29.6817 |
| 2010's | 11 (22.00) | 24.3611 |
| 2020's | 3 (6.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clark, RL | 1 |
| Pessolano, AA | 1 |
| Witzel, B | 1 |
| Lanza, T | 1 |
| Shen, TY | 1 |
| Van Arman, CG | 1 |
| Risley, EA | 1 |
| Lazer, ES | 1 |
| Matteo, MR | 1 |
| Possanza, GJ | 1 |
| Rovnyak, GC | 1 |
| Millonig, RC | 2 |
| Schwartz, J | 1 |
| Shu, V | 1 |
| Wade, PC | 1 |
| Vogt, BR | 1 |
| Kissick, TP | 1 |
| Simpkins, LM | 1 |
| Palmer, DM | 1 |
| Schlegel, DC | 1 |
| Zenitz, BL | 1 |
| Fellows, CA | 1 |
| Laskowski, SC | 1 |
| Behn, DC | 1 |
| Phillips, DK | 1 |
| Botton, I | 1 |
| Speight, PT | 1 |
| Boettcher, I | 1 |
| Elger, W | 1 |
| Kirsch, G | 1 |
| Siegmund, F | 1 |
| Wachtel, H | 1 |
| Hino, K | 1 |
| Nakamura, H | 2 |
| Nagai, Y | 1 |
| Uno, H | 1 |
| Nishimura, H | 1 |
| Powers, LJ | 1 |
| Fogt, SW | 1 |
| Ariyan, ZS | 1 |
| Rippin, DJ | 1 |
| Heilman, RD | 1 |
| Matthews, RJ | 1 |
| Calhoun, W | 1 |
| Carlson, RP | 1 |
| Crossley, R | 1 |
| Datko, LJ | 1 |
| Dietrich, S | 1 |
| Heatherington, K | 1 |
| Marshall, LA | 1 |
| Meade, PJ | 1 |
| Opalko, A | 1 |
| Shepherd, RG | 1 |
| Wilkerson, WW | 1 |
| Galbraith, W | 1 |
| Gans-Brangs, K | 1 |
| Grubb, M | 1 |
| Hewes, WE | 1 |
| Jaffee, B | 1 |
| Kenney, JP | 1 |
| Kerr, J | 1 |
| Wong, N | 1 |
| Siskou, IC | 1 |
| Rekka, EA | 1 |
| Kourounakis, AP | 1 |
| Chrysselis, MC | 1 |
| Tsiakitzis, K | 1 |
| Kourounakis, PN | 1 |
| Shin, JS | 1 |
| Noh, YS | 1 |
| Yoo, MS | 1 |
| Lee, JY | 2 |
| Cho, YW | 1 |
| Lee, KT | 1 |
| Zhang, NY | 1 |
| Wang, TH | 1 |
| Chou, CH | 1 |
| Wu, KC | 1 |
| Yang, CR | 1 |
| Kung, FL | 1 |
| Lin, CJ | 1 |
| Choudhary, N | 1 |
| Gupta, R | 1 |
| Bhatt, LK | 1 |
| Ames, FQ | 1 |
| Bracht, L | 1 |
| Schneider, LCL | 1 |
| Rocha, BA | 1 |
| Santos, GA | 1 |
| Lima, EP | 1 |
| Rocha, EMT | 1 |
| Cuman, RKN | 1 |
| Bersani-Amado, CA | 1 |
| Corrêa, MG | 1 |
| Pires, PR | 1 |
| Ribeiro, FV | 1 |
| Pimentel, SP | 1 |
| Cirano, FR | 1 |
| Napimoga, MH | 1 |
| Casati, MZ | 1 |
| Casarin, RCV | 1 |
| Micheli, L | 1 |
| Ghelardini, C | 1 |
| Lucarini, E | 1 |
| Parisio, C | 1 |
| Trallori, E | 1 |
| Cinci, L | 1 |
| Di Cesare Mannelli, L | 1 |
| Bi, RY | 1 |
| Ding, Y | 1 |
| Gan, YH | 1 |
| Park, JW | 1 |
| Yun, YP | 1 |
| Park, K | 1 |
| Kim, HJ | 1 |
| Kim, SE | 1 |
| Song, HR | 1 |
| Uraki, M | 2 |
| Kawase, A | 3 |
| Iwaki, M | 3 |
| Ikuta, H | 2 |
| Hatori, M | 1 |
| Ohki, K | 1 |
| Hirano, S | 1 |
| Yang, XP | 1 |
| Kuboki, H | 1 |
| Abe, C | 1 |
| Uno, S | 1 |
| Komura, H | 1 |
| Kanashiro, A | 1 |
| Pessini, AC | 1 |
| Machado, RR | 1 |
| Malvar, Ddo C | 1 |
| Aguiar, FA | 1 |
| Soares, DM | 1 |
| do Vale, ML | 1 |
| de Souza, GE | 1 |
| Huang, L | 1 |
| Mackenzie, G | 1 |
| Ouyang, N | 1 |
| Sun, Y | 1 |
| Xie, G | 1 |
| Johnson, F | 1 |
| Komninou, D | 1 |
| Rigas, B | 1 |
| Driban, JB | 1 |
| Barr, AE | 1 |
| Amin, M | 1 |
| Sitler, MR | 1 |
| Barbe, MF | 1 |
| Kaur, S | 1 |
| Bijjem, KR | 1 |
| Sharma, PL | 1 |
| Chauhan, PS | 1 |
| Satti, NK | 1 |
| Sharma, P | 1 |
| Sharma, VK | 1 |
| Suri, KA | 1 |
| Bani, S | 1 |
| Mourouzis, C | 1 |
| Saranteas, T | 1 |
| Tsamouris, M | 1 |
| Tesseromatis, C | 1 |
| Banerjee, M | 1 |
| Tripathi, LM | 1 |
| Srivastava, VM | 1 |
| Puri, A | 1 |
| Shukla, R | 1 |
| Rovenský, J | 1 |
| Svík, K | 1 |
| Istok, R | 1 |
| Stancíková, M | 1 |
| Kalia, R | 1 |
| Rao, CM | 1 |
| Kutty, NG | 1 |
| Martel, RR | 1 |
| Klicius, J | 1 |
| Metcalf, G | 1 |
| Rona, GA | 1 |
| Pawłowski, K | 2 |
| Bossoni, G | 1 |
| Coppi, G | 1 |
| Lumachi, B | 1 |
| Milanino, R | 1 |
| Passarella, E | 1 |
| Toson, G | 1 |
| Valsecchi, B | 1 |
| Smith-Oliver, T | 1 |
| Noel, LS | 1 |
| Stimpson, SS | 1 |
| Yarnall, DP | 1 |
| Connolly, KM | 1 |
| Selph, JL | 1 |
| Boncek, VM | 1 |
| Soroko, FE | 1 |
| Harris, TM | 1 |
| Cochran, FR | 1 |
| Futaki, N | 1 |
| Yoshikawa, K | 1 |
| Hamasaka, Y | 1 |
| Arai, I | 1 |
| Higuchi, S | 1 |
| Iizuka, H | 1 |
| Otomo, S | 1 |
| Liso, PA | 1 |
| Rebuelta, M | 1 |
| San Román, J | 1 |
| Gallardo, A | 1 |
| Villar, AM | 1 |
| Price, DD | 1 |
| Mao, J | 1 |
| Lu, J | 1 |
| Caruso, FS | 1 |
| Frenk, H | 1 |
| Mayer, DJ | 1 |
| Sacco, S | 1 |
| Agnello, D | 1 |
| Sottocorno, M | 1 |
| Lozza, G | 1 |
| Monopoli, A | 1 |
| Villa, P | 1 |
| Ghezzi, P | 1 |
| Lichtenberger, LM | 1 |
| Romero, JJ | 1 |
| de Ruijter, WM | 1 |
| Behbod, F | 1 |
| Darling, R | 1 |
| Ashraf, AQ | 1 |
| Sanduja, SK | 1 |
| Binderup, L | 1 |
| Bramm, E | 1 |
| Arrigoni-Martelli, E | 1 |
| Sharma, JN | 2 |
| Aparicio, L | 1 |
| Hidaka, T | 1 |
| Hosoe, K | 1 |
| Yamashita, T | 1 |
| Watanabe, K | 1 |
| Hiramatsu, Y | 1 |
| Fujimura, H | 1 |
| Motoyoshi, S | 1 |
| Ishii, K | 1 |
| Kadokawa, T | 1 |
| Fujiyoshi, T | 1 |
| Iida, H | 1 |
| Saito, M | 1 |
| Ikeda, K | 1 |
| Yamaura, T | 1 |
| Uematsu, T | 1 |
| Hunneyball, IM | 1 |
| Crossley, MJ | 1 |
| Spowage, M | 1 |
50 other studies available for ibuprofen and Adjuvant Arthritis
| Article | Year |
|---|---|
2-(Substituted phenyl)oxazolo[4,5-b]pyridines and 2-(substituted phenyl)oxazolo[5,4-b]pyridines as nonacidic antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1978 |
Benzimidazole derivatives with atypical antiinflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Benzimidazoles | 1987 |
Synthesis and antiinflammatory activity of hexahydrothiopyrano[4,3-c]pyrazoles and related analogues.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Chemical Phenomena; Che | 1982 |
1-Acyltriazoles as antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Edema; Ibuprofen; Male; | 1982 |
Bulky amine analogues of ketoprofen: potent antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Chemical Phenomena; Chemistry; Drug Eval | 1984 |
Nonsteroidal antiinflammatory agents. 14. Synthesis and pharmacological profile of 6-chloro-5-(cyclopentylmethyl)indan-1-carboxylic acid.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Edema; Indans; Indenes; M | 1984 |
Nonsteroidal antiinflammatory agents. 2. [(Heteroarylamino)phenyl]alkanoic acids.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carboxylic Acids; Carrageenan; Edema; Fe | 1983 |
Effect of structural change on acute toxicity and antiinflammatory activity in a series of imidazothiazoles and thiazolobenzimidazoles.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1981 |
Synthesis and antiinflammatory activity of certain 5,6,7,8-tetrahydroquinolines and related compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Female; Male; Quinolines; | 1995 |
Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Disease Models, Animal; D | 1994 |
Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties.
Topics: Animals; Antioxidants; Arthritis, Experimental; Biphenyl Compounds; Blood-Brain Barrier; Cholesterol | 2007 |
Anti-inflammatory and anti-arthritic effects of new synthetic 3-(4-hydroxyphenyl)-4-(4-thiomethoxyphenyl)-1H-pyrrole-2,5-dione.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Carrageenan; Cyclo | 2012 |
Ibuprofen treatment ameliorates memory deficits in rats with collagen-induced arthritis by normalizing aberrant MAPK/NF-κB and glutamatergic pathways.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cytokines; Excitatory Amino Acid Transporte | 2022 |
Anti-rheumatic activity of Phenethyl isothiocyanate via inhibition of histone deacetylase-1.
Topics: Analgesics, Non-Narcotic; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumat | 2020 |
Anti-inflammatory Effect of Low-Dose Anethole and Ibuprofen Combination Is Accompanied by Partial Prevention of Hepatic Metabolic Changes in Arthritic Rats.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Exp | 2020 |
Systemic treatment with resveratrol reduces the progression of experimental periodontitis and arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cartilage, Articular; Dis | 2018 |
Intra-articular mucilages: behavioural and histological evaluations for a new model of articular pain.
Topics: Althaea; Analgesics; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Flax; Freund's Adjuvan | 2019 |
Non-steroidal Anti-inflammatory Drugs Attenuate Hyperalgesia and Block Upregulation of Trigeminal Ganglionic Sodium Channel 1.7 after Induction of Temporomandibular Joint Inflammation in Rats.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; D | 2016 |
Ibuprofen-loaded porous microspheres suppressed the progression of monosodium iodoacetate-induced osteoarthritis in a rat model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Proliferation; Chond | 2016 |
Stereoselective hepatic disposition of ibuprofen in the perfused liver of rat with adjuvant-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Ibuprofen; Liver; Male; R | 2017 |
Stereoselective Pharmacokinetics and Chiral Inversion of Ibuprofen in Adjuvant-induced Arthritic Rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Blood Proteins; Cytochrom | 2017 |
Effects of a casein hydrolysate prepared from Aspergillus oryzae protease on adjuvant arthritis in rats.
Topics: Animals; Arthritis, Experimental; Aspergillus oryzae; Body Weight; Caseins; Dinoprostone; Female; Ib | 2008 |
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Coenzyme A Ligases; Femal | 2008 |
Characterization and pharmacological evaluation of febrile response on zymosan-induced arthritis in rats.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Arthritis, Experimental; Body Temperature; Celecox | 2009 |
The novel phospho-non-steroidal anti-inflammatory drugs, OXT-328, MDC-22 and MDC-917, inhibit adjuvant-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Cell Line; Cytok | 2011 |
Joint inflammation and early degeneration induced by high-force reaching are attenuated by ibuprofen in an animal model of work-related musculoskeletal disorder.
Topics: Animals; Arthritis, Experimental; Cartilage Diseases; Cartilage, Articular; Chondrocytes; Collagen; | 2011 |
Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Disease Models, Animal; Dose | 2011 |
Differential effects of chlorogenic acid on various immunological parameters relevant to rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; B7-1 Antigen; B7-2 Antigen; CD28 Antigens; C | 2012 |
Morphological changes of parotid glands following adjuvant arthritis and ibuprofen treatment in rats.
Topics: Adjuvants, Immunologic; Adrenal Glands; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non | 2003 |
Modulation of inflammatory mediators by ibuprofen and curcumin treatment during chronic inflammation in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; C-Reactive Protein; Chron | 2003 |
Quantitative assessment of markers of inflammation, arthritis and pain in rats with adjuvant arthritis following the treatment with ibuprofen cream and placebo.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental | 2003 |
Synthesis and evaluation of the antiinflammatory activity of N-[2-(3,5-di-tert-butyl-4-hydroxyphenyl)-4-oxo-thiazolidin-3-yl]-nicotinamide.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Arthritis, Exp | 2007 |
Comparative effects of long term treatment with etodolac, naproxen and ibuprofen on articular and bone changes associated with adjuvant arthritis in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Body Weight; Bone a | 1984 |
Haptoglobin and copper in adjuvant arthritis during the ibuprofen therapy.
Topics: Animals; Arthritis; Arthritis, Experimental; Copper; Female; Haptoglobins; Ibuprofen; Male; Rats; Ra | 1984 |
[Pharmacologic profile of a new compound with antiinflammatory activity: 2-(4-dimethylvinylphenyl)propionic acid (Gx 258)].
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1984 |
Elevated levels of TNF in the joints of adjuvant arthritic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Biological Assay; Cells, | 1993 |
The pharmacologic evaluation of locomotor activity versus inflammatory parameters in rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Female; Fibrinogen; Ibuprofen; Joints; Leukocyte Count; Motor Acti | 1993 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena | 1993 |
Polymeric drugs derived from ibuprofen with improved antiinflammatory profile.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; | 1996 |
Effects of the combined oral administration of NSAIDs and dextromethorphan on behavioral symptoms indicative of arthritic pain in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Beh | 1996 |
Nonsteroidal anti-inflammatory drugs increase tumor necrosis factor production in the periphery but not in the central nervous system in mice and rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Brain; Brain Ischemia; En | 1998 |
Phosphatidylcholine association increases the anti-inflammatory and analgesic activity of ibuprofen in acute and chronic rodent models of joint inflammation: relationship to alterations in bioavailability and cyclooxygenase-inhibitory potency.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 2001 |
Characterization of inhibitor(s) of lymphocyte activation in serum from rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Chemical Fractionation; Chromatography, Gel; Concanaval | 1978 |
Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Female; Ibuprofen; Male; Myco | 1977 |
Some aspects of the pharmacology of butibufen, a non-steroidal anti-inflammatory agent.
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspirin; Edema; Gr | 1977 |
Analgesic and anti-inflammatory activities in rats of alpha-(3,5-di-t-butyl-4-hydroxybenzylidene)-gamma-butyrolactone (KME-4), and its intestinal damage.
Topics: 4-Butyrolactone; Acetates; Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 1986 |
[Inhibitory effect of AD-1590, a non-steroidal anti-inflammatory drug, on allergic inflammation in mice and rats].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experimental; Dermatitis, Co | 1988 |
[The analgesic and antipyretic effects of a non-steroidal antiinflammatory agent, EB-382, in experimental animals].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Ibuprofen; Indom | 1986 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. I. Characterization of the arthritis and the effects of steroidal and non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Flurbi | 1986 |
Proteolytic and beta-glucuronidase activity in adjuvant arthritis during the ibuprofen therapy.
Topics: Animals; Arthritis; Arthritis, Experimental; Female; Glucuronidase; Ibuprofen; Kinetics; Male; Pepti | 1985 |