Page last updated: 2024-10-28

ibuprofen and Adenocarcinoma

ibuprofen has been researched along with Adenocarcinoma in 14 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" We report that both indomethacin and ibuprofen improved body weight and weight of the gastrocnemius muscle in tumor-bearing mice."7.72Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. ( Al-Majid, S; Hitt, A; McCarthy, DO; Whitney, P, 2004)
"When ibuprofen was given in combination with a cytotoxic drug, the primary cytoreductive effect was that of the cytotoxic agent."5.27Response of human adenocarcinoma to chemotherapy: as sole agents and in combination with sodium ibuprofen. ( Braly, PS; DiSaia, PJ; Stratton, JA, 1984)
" We report that both indomethacin and ibuprofen improved body weight and weight of the gastrocnemius muscle in tumor-bearing mice."3.72Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma. ( Al-Majid, S; Hitt, A; McCarthy, DO; Whitney, P, 2004)
"Ibuprofen, therefore, is a potential therapeutic agent that might allow lowering the doses of cisplatin and limiting the many challenge associated with its toxicity and development of drug resistance."1.40Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70. ( Endo, H; Kido, H; Okumura, Y; Yano, M, 2014)
"Ibuprofen was significantly more effective against human prostate cancer cells in vitro than the other tested nonprescription NSAIDs."1.31Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells. ( Andrews, J; Andrews, P; Djakiew, D; Krygier, S, 2002)
"Smoking is a documented risk factor for pancreatic cancer, and the risk is increased in smokers who also consume alcohol."1.31The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK. ( Castonguay, A; Miller, MS; Schuller, HM; Walker, K; Weddle, DL; Zhang, L, 2002)
" These agents were tested either alone for the prevention of metastasis or in combination with IL-2 for the eradication of established metastasis."1.28Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclo-oxygenase inhibitors alone or in combination with IL-2. ( Chan, FP; Khoo, NK; Lala, PK; Saarloos, MN, 1992)
" In NMU cells, a linear dose-response inhibitory pattern was discernable, whereas in RBA cells a biphasic pattern was observed; PGE2 levels increased at low concentrations of ibuprofen and then decreased at higher concentrations."1.27Endogenous prostaglandin production by established cultures of neoplastic rat mammary epithelial cells. ( Cohen, LA; Karmali, RA, 1984)
"When ibuprofen was given in combination with a cytotoxic drug, the primary cytoreductive effect was that of the cytotoxic agent."1.27Response of human adenocarcinoma to chemotherapy: as sole agents and in combination with sodium ibuprofen. ( Braly, PS; DiSaia, PJ; Stratton, JA, 1984)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sahin, A1
Spiroux, F1
Guedon, I1
Arslan, FB1
Sarcan, ET1
Ozkan, T1
Colak, N1
Yuksel, S1
Ozdemir, S1
Ozdemir, B1
Akbas, S1
Ultav, G1
Aktas, Y1
Capan, Y1
Endo, H1
Yano, M1
Okumura, Y1
Kido, H1
Bonelli, P1
Tuccillo, FM1
Calemma, R1
Pezzetti, F1
Borrelli, A1
Martinelli, R1
De Rosa, A1
Esposito, D1
Palaia, R1
Castello, G1
Andrews, J1
Djakiew, D1
Krygier, S1
Andrews, P1
Schuller, HM1
Zhang, L1
Weddle, DL1
Castonguay, A1
Walker, K1
Miller, MS1
McCarthy, DO1
Whitney, P1
Hitt, A1
Al-Majid, S1
Cohen, LA1
Karmali, RA2
Stratton, JA2
Braly, PS2
DiSaia, PJ2
Rettenmaier, MA1
Schwenger, P1
Alpert, D1
Skolnik, EY1
Vilcek, J1
Williams, JL1
Borgo, S1
Hasan, I1
Castillo, E1
Traganos, F1
Rigas, B1
Hodgson, DM1
Yirmiya, R1
Taylor, AN1
Khoo, NK1
Chan, FP1
Saarloos, MN1
Lala, PK1
Marsh, J1

Other Studies

14 other studies available for ibuprofen and Adenocarcinoma

ArticleYear
Using PVA and TPGS as combined emulsifier in nanoprecipitation method improves characteristics and anticancer activity of ibuprofen loaded PLGA nanoparticles.
    Die Pharmazie, 2017, Sep-01, Volume: 72, Issue:9

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Chemistry, Pharmaceu

2017
Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70.
    Cell death & disease, 2014, Jan-30, Volume: 5

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplati

2014
Changes in the gene expression profile of gastric cancer cells in response to ibuprofen: a gene pathway analysis.
    The pharmacogenomics journal, 2011, Volume: 11, Issue:6

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Line, Tumor; Flow Cytometry

2011
Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.
    Cancer chemotherapy and pharmacology, 2002, Volume: 50, Issue:4

    Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Divis

2002
The cyclooxygenase inhibitor ibuprofen and the FLAP inhibitor MK886 inhibit pancreatic carcinogenesis induced in hamsters by transplacental exposure to ethanol and the tobacco carcinogen NNK.
    Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:10

    Topics: Adenocarcinoma; Animals; Arachidonic Acid; Cricetinae; Cyclooxygenase Inhibitors; DNA Primers; Ethan

2002
Indomethacin and ibuprofen preserve gastrocnemius muscle mass in mice bearing the colon-26 adenocarcinoma.
    Research in nursing & health, 2004, Volume: 27, Issue:3

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Cachexia; Colonic Neo

2004
Endogenous prostaglandin production by established cultures of neoplastic rat mammary epithelial cells.
    In vitro, 1984, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Animals; Cell Division; Cell Line; Epithelium; Female; Ibuprofen; Mammary Neoplasms,

1984
Response of human adenocarcinoma to chemotherapy: as sole agents and in combination with sodium ibuprofen.
    Gynecologic oncology, 1984, Volume: 18, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cycl

1984
Depressed natural killer cell activity in tumor-bearing rats: effect of immunotherapy and cytoreductive chemotherapy.
    Clinical immunology and immunopathology, 1983, Volume: 28, Issue:2

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adenocarcinoma; Adjuvants, Immunologic; Animals; Cisplatin; Cytot

1983
Cell-type-specific activation of c-Jun N-terminal kinase by salicylates.
    Journal of cellular physiology, 1999, Volume: 179, Issue:1

    Topics: Acetaminophen; Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium-Ca

1999
Nitric oxide-releasing nonsteroidal anti-inflammatory drugs (NSAIDs) alter the kinetics of human colon cancer cell lines more effectively than traditional NSAIDs: implications for colon cancer chemoprevention.
    Cancer research, 2001, Apr-15, Volume: 61, Issue:8

    Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Aspirin

2001
Intracerebroventricular interleukin-1beta impairs clearance of tumor cells from the lungs: role of brain prostaglandins.
    Journal of neuroimmunology, 2001, Sep-03, Volume: 119, Issue:1

    Topics: Adenocarcinoma; Animals; Brain; Cyclooxygenase Inhibitors; Diclofenac; Ibuprofen; Injections, Intrav

2001
Immunotherapy of mammary adenocarcinoma metastases in C3H/HeN mice with chronic administration of cyclo-oxygenase inhibitors alone or in combination with IL-2.
    Clinical & experimental metastasis, 1992, Volume: 10, Issue:4

    Topics: Adenocarcinoma; Animals; Cell Division; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Female

1992
Antitumor activity in a rat mammary adenocarcinoma: the effect of cyclooxygenase inhibitors and immunization against prostaglandin E2.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Animals; Antibodies; Antineoplastic Agents; Cell Line; Cyclooxygenase Inhibitors; Di

1985