ibuprofen has been researched along with Acute Liver Injury, Drug-Induced in 51 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report herein a case of an adult patient who had persistent cholestasis with hyperlipidemia from the VBDS after ibuprofen use." | 7.88 | Vanishing bile duct syndrome with hyperlipidemia after ibuprofen therapy in an adult patient: a case report. ( Gao, Y; Pan, CQ; Wang, Q; Xie, W, 2018) |
| " Drug lymphocyte stimulation tests implicated ibuprofen, a main component of the OTC drugs, which has the potential to induce this pathology, and a diagnosis of drug-induced liver injury with multiform exudative erythema was made." | 7.81 | Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen. ( Abe, M; Aritomo, K; Hiasa, Y; Hirooka, M; Ikeda, Y; Koizumi, Y; Kumagi, T; Matsuura, B; Ochi, H; Tada, F; Tokumoto, Y; Watanabe, T, 2015) |
| " This case suggests that disseminated intravascular coagulation, and its rare association with hepatotoxicity, is a potentially fatal side effect of aspirin therapy." | 5.26 | Aspirin hepatotoxicity and disseminated intravascular coagulation. ( Bennett, RM; Sbarbaro, JA, 1977) |
| "We report herein a case of an adult patient who had persistent cholestasis with hyperlipidemia from the VBDS after ibuprofen use." | 3.88 | Vanishing bile duct syndrome with hyperlipidemia after ibuprofen therapy in an adult patient: a case report. ( Gao, Y; Pan, CQ; Wang, Q; Xie, W, 2018) |
| " Drug lymphocyte stimulation tests implicated ibuprofen, a main component of the OTC drugs, which has the potential to induce this pathology, and a diagnosis of drug-induced liver injury with multiform exudative erythema was made." | 3.81 | Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen. ( Abe, M; Aritomo, K; Hiasa, Y; Hirooka, M; Ikeda, Y; Koizumi, Y; Kumagi, T; Matsuura, B; Ochi, H; Tada, F; Tokumoto, Y; Watanabe, T, 2015) |
| "The risk of a newly diagnosed episode of upper gastrointestinal bleeding, acute liver and renal failure, agranulocytosis, aplastic anemia, severe skin disorders, and anaphylaxis was examined within 30 days after the first prescription for a low dose of diclofenac, naproxen, or ibuprofen in a cohort in the United Kingdom." | 3.70 | Low-dose diclofenac, naproxen, and ibuprofen cohort study. ( Duque-Oliart, A; García-Rodríguez, LA; Pérez-Gutthann, S; Varas-Lorenzo, C, 1999) |
| " Documentation is derived from clinical trials, post-marketing surveillance, special studies, and spontaneous reports of adverse drug reactions from foreign countries." | 2.66 | Worldwide safety experience with diclofenac. ( Catalano, MA, 1986) |
| "Since its introduction in the United States in 1974, ibuprofen (Motrin, Upjohn) has been shown to be safe and effective for the treatment of pain, dysmenorrhea, inflammation, and fever." | 2.65 | Safety profile: fifteen years of clinical experience with ibuprofen. ( Royer, GL; Seckman, CE; Welshman, IR, 1984) |
| "Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used for its analgesic, antipyretic and anti-inflammatory effects worldwide." | 1.72 | Trichopus zeylanicus ameliorates ibuprofen inebriated hepatotoxicity and enteropathy: an insight into its modulatory impact on pro/anti-inflammatory cytokines and apoptotic signaling pathways. ( Panchal, NK; Prince, SE; Swarnalatha, P, 2022) |
| "Ibuprofen is a worldwide used non-steroidal anti-inflammatory drug which may cause acute liver injury (ALI) requiring liver transplantation." | 1.51 | Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury. ( Andrade, RJ; Bast, A; Bechmann, LP; Cubero, FJ; Koek, GH; Lucena, MI; Nelson, LJ; Sydor, S; Trautwein, C; Woitok, MM; Zoubek, ME, 2019) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| " Appropriate dosing and managing of these drugs do not likely lead to organ toxicity." | 1.35 | Acute non-oliguric kidney failure and cholestatic hepatitis induced by ibuprofen and acetaminophen: a case report. ( Angeli, S; Brugnara, M; Cuzzolin, L; Zaffanello, M, 2009) |
| " HSA irreversible alkylation represents a model for other proteins to be potentially toxic and thus may help explain zileuton hepatotoxicity." | 1.34 | Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity. ( Chordia, MD; Li, F; Macdonald, TL; Woodling, KA, 2007) |
| " In therapeutic dosage it will adequately control joint symptoms in the majority of patients." | 1.26 | Pharmacotherapy of juvenile rheumatoid arthritis. ( Lindsley, CB, 1981) |
| " This case suggests that disseminated intravascular coagulation, and its rare association with hepatotoxicity, is a potentially fatal side effect of aspirin therapy." | 1.26 | Aspirin hepatotoxicity and disseminated intravascular coagulation. ( Bennett, RM; Sbarbaro, JA, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (21.57) | 18.7374 |
| 1990's | 6 (11.76) | 18.2507 |
| 2000's | 10 (19.61) | 29.6817 |
| 2010's | 21 (41.18) | 24.3611 |
| 2020's | 3 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Morgan, RE | 1 |
| Trauner, M | 1 |
| van Staden, CJ | 1 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 1 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 3 |
| Dawson, S | 1 |
| Stahl, S | 2 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Theodosis-Nobelos, P | 1 |
| Athanasekou, C | 1 |
| Rekka, EA | 1 |
| Kitahara, M | 1 |
| Sakamoto, H | 1 |
| Kimura, R | 1 |
| Ikoma-Seki, K | 1 |
| Panchal, NK | 1 |
| Swarnalatha, P | 1 |
| Prince, SE | 1 |
| Zoubek, ME | 3 |
| Lucena, MI | 4 |
| Andrade, RJ | 4 |
| Stephens, C | 2 |
| González-Jimenez, A | 1 |
| Medina-Cáliz, I | 1 |
| Robles-Díaz, M | 1 |
| Hernandez, N | 1 |
| Romero-Gómez, M | 1 |
| Bessone, F | 1 |
| Hallal, H | 1 |
| Cubero, FJ | 2 |
| Thiede, A | 1 |
| Zimmermann, HJ | 1 |
| Woitok, MM | 1 |
| Sydor, S | 1 |
| Nelson, LJ | 1 |
| Bechmann, LP | 1 |
| Bast, A | 1 |
| Koek, GH | 1 |
| Trautwein, C | 1 |
| Xie, W | 1 |
| Wang, Q | 1 |
| Gao, Y | 1 |
| Pan, CQ | 1 |
| Lu, W | 1 |
| Cheng, F | 1 |
| Jiang, J | 1 |
| Zhang, C | 1 |
| Deng, X | 1 |
| Xu, Z | 1 |
| Zou, S | 1 |
| Shen, X | 1 |
| Tang, Y | 1 |
| Huang, J | 1 |
| Watanabe, T | 1 |
| Abe, M | 1 |
| Tada, F | 1 |
| Aritomo, K | 1 |
| Ochi, H | 1 |
| Koizumi, Y | 1 |
| Tokumoto, Y | 1 |
| Hirooka, M | 1 |
| Kumagi, T | 1 |
| Ikeda, Y | 1 |
| Matsuura, B | 1 |
| Hiasa, Y | 1 |
| Tanino, T | 1 |
| Funakami, Y | 1 |
| Nagai, N | 1 |
| Kato, Y | 1 |
| Donati, M | 1 |
| Conforti, A | 1 |
| Lenti, MC | 1 |
| Capuano, A | 1 |
| Bortolami, O | 1 |
| Motola, D | 1 |
| Moretti, U | 1 |
| Vannacci, A | 1 |
| Rafaniello, C | 1 |
| Vaccheri, A | 1 |
| Arzenton, E | 1 |
| Bonaiuti, R | 1 |
| Sportiello, L | 1 |
| Leone, R | 1 |
| Bennett, WE | 1 |
| Turmelle, YP | 1 |
| Shepherd, RW | 1 |
| Zaffanello, M | 1 |
| Brugnara, M | 1 |
| Angeli, S | 1 |
| Cuzzolin, L | 1 |
| Hotermans, C | 1 |
| Belachew, S | 1 |
| Moonen, G | 1 |
| Delwaide, J | 1 |
| Argentieri, J | 1 |
| Morrone, K | 1 |
| Pollack, Y | 1 |
| García-Cortés, M | 1 |
| García-Ruiz, E | 1 |
| Fernández-Bonilla, E | 1 |
| Vázquez, L | 1 |
| Li, F | 1 |
| Chordia, MD | 1 |
| Woodling, KA | 1 |
| Macdonald, TL | 1 |
| Yasuda, H | 1 |
| Yoshiba, S | 1 |
| Elkrief, L | 1 |
| Chryssostalis, A | 1 |
| Moachon, L | 1 |
| Franck, N | 1 |
| Terris, B | 1 |
| Chaussade, S | 1 |
| Sogni, P | 1 |
| Royer, GL | 1 |
| Seckman, CE | 1 |
| Welshman, IR | 1 |
| Sternlieb, P | 2 |
| Robinson, RM | 2 |
| Lindsley, CB | 1 |
| Ward, PH | 1 |
| Maldonado, M | 1 |
| Roa, J | 1 |
| Manríquez, V | 1 |
| Vivaldi, E | 1 |
| Maria, VA | 1 |
| Pinto, L | 1 |
| Victorino, RM | 1 |
| Barriault, C | 1 |
| Audet, M | 1 |
| Yousef, IM | 1 |
| Tuchweber, B | 1 |
| Vigouroux, C | 1 |
| Fitoussi, D | 1 |
| Cariou, D | 1 |
| Aerts, J | 1 |
| Pasquier, P | 1 |
| Riley, TR | 1 |
| Smith, JP | 1 |
| Pérez-Gutthann, S | 1 |
| García-Rodríguez, LA | 1 |
| Duque-Oliart, A | 1 |
| Varas-Lorenzo, C | 1 |
| Laurent, S | 1 |
| Rahier, J | 1 |
| Geubel, AP | 1 |
| Lerut, J | 1 |
| Horsmans, Y | 1 |
| Borel, I | 1 |
| Hedelius, F | 1 |
| Baumgartner, C | 1 |
| Vial, T | 1 |
| Scoazec, JY | 1 |
| Dumortier, J | 1 |
| Morelli, MS | 1 |
| O'Brien, FX | 1 |
| Sbarbaro, JA | 1 |
| Bennett, RM | 1 |
| Stempel, DA | 1 |
| Miller, JJ | 1 |
| Schlegel, SI | 1 |
| Paulus, HE | 1 |
| Catalano, MA | 1 |
| Wendel, A | 1 |
| Tiegs, G | 1 |
| Lee, CY | 1 |
| Finkler, A | 1 |
| O'Brien, WM | 1 |
| Bagby, GF | 1 |
8 reviews available for ibuprofen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Systematic review: ibuprofen-induced liver injury.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Chemical and | 2020 |
Acetaminophen and Ibuprofen overdosage.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Chemical and Drug Induced Live | 2012 |
[Fulminant hepatitis].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Age | 2007 |
[Disclosure of systemic lupus erythematosus in a case of hepatitis caused by ibuprofen].
Topics: Adult; Chemical and Drug Induced Liver Injury; Female; Humans; Ibuprofen; Lupus Erythematosus, Syste | 1993 |
Stevens-Johnson Syndrome and cholestatic hepatitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cholestasis; | 2001 |
Non-steroidal and analgesic therapy in the elderly.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Apazone; Aspirin; Cen | 1986 |
Rare adverse reactions to nonsteroidal antiinflammatory drugs (3).
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Chemical and Drug Induced Liver Injury; | 1985 |
3 trials available for ibuprofen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Safety profile: fifteen years of clinical experience with ibuprofen.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Cell Count; Blood Coagulation Tests; Blood Proteins; Centra | 1984 |
Lymphocyte reactivity to ex-vivo drug antigens in drug-induced hepatitis.
Topics: Adult; Ampicillin; Antigens; Cell Division; Cells, Cultured; Chemical and Drug Induced Liver Injury; | 1994 |
Worldwide safety experience with diclofenac.
Topics: Adult; Aged; Aspirin; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Diclo | 1986 |
40 other studies available for ibuprofen and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Dual antioxidant structures with potent anti-inflammatory, hypolipidemic and cytoprotective properties.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Butanes; Carrageenan; Chemical and D | 2017 |
[A protective effect of acetaminophen on ibuprofen-induced small intestinal damage in rats via the suppression of MMP-13].
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Ibuprofen; Intestine, Small; Liver; | 2021 |
Trichopus zeylanicus ameliorates ibuprofen inebriated hepatotoxicity and enteropathy: an insight into its modulatory impact on pro/anti-inflammatory cytokines and apoptotic signaling pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Chemical and Drug Induced | 2022 |
High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Dr | 2018 |
Topics: Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Cortisone; Diagnosis, Differentia | 2017 |
Protective role of c-Jun N-terminal kinase-2 (JNK2) in ibuprofen-induced acute liver injury.
Topics: Animals; Cell Death; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Enzyme Activati | 2019 |
Vanishing bile duct syndrome with hyperlipidemia after ibuprofen therapy in an adult patient: a case report.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cholestasis; | 2018 |
FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Genetic Predisposit | 2015 |
Drug-induced liver injury with serious multiform exudative erythema following the use of an over-the-counter medication containing ibuprofen.
Topics: Adult; Asian People; Chemical and Drug Induced Liver Injury; Drug Eruptions; Erythema; Female; Fever | 2015 |
Cyclosporin A-sensitive cytotoxicity of flurbiprofen non-stereoselectively mediated by cytochrome P450 metabolism in three-dimensional cultured rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Cyclosporine; Cytochrome P- | 2015 |
Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case-control study in Italy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Chemical and Drug Induce | 2016 |
Ibuprofen-induced liver injury in an adolescent athlete.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Baseball; Chemical and Drug Induced Liver Injur | 2009 |
Acute non-oliguric kidney failure and cholestatic hepatitis induced by ibuprofen and acetaminophen: a case report.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury | 2009 |
Severe liver dysfunction in a patient with multiple sclerosis: the guilty party is not always the disease-modifying therapy.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Female; Glat | 2009 |
Basic pain relievers. It's wise to use caution.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemical and Drug Induc | 2012 |
Chronic hepatitis C, ibuprofen, and liver damage.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Hepa | 2002 |
Irreversible alkylation of human serum albumin by zileuton metabolite 2-acetylbenzothiophene-S-oxide: a potential model for hepatotoxicity.
Topics: Alkylation; Anti-Asthmatic Agents; Binding, Competitive; Chemical and Drug Induced Liver Injury; Chr | 2007 |
[Severe cholestatic hepatitis associated with Stevens-Johnson syndrome after taking ibuprofen].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cholestasis, | 2007 |
Side effects of ibuprofen.
Topics: Chemical and Drug Induced Liver Injury; Drug Eruptions; Humans; Ibuprofen | 1980 |
Pharmacotherapy of juvenile rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Antimalarials; Arthritis, Juvenile; Chemical and Drug Induced Liver Injury; | 1981 |
Ibuprofen protects rat livers from oxygen-derived free radical-mediated injury after tourniquet shock.
Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Evaluation Studies as Topic; | 1995 |
Protection by indomethacin against the lethality and hepatotoxicity of phalloidin in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Aspirin; Chemical and Drug Induced Liver | 1994 |
Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis C: a case series.
Topics: Adult; Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; C | 1998 |
Low-dose diclofenac, naproxen, and ibuprofen cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agen | 1999 |
Subfulminant hepatitis requiring liver transplantation following ibuprofen overdose.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Drug Overdose; Fema | 2000 |
[Severe acute hepatitis associated with ibuprofen treatment].
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Ibuprofen | 2001 |
Stevens-Johnson syndrome plus toxic hepatitis due to ibuprofen.
Topics: Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Female; Humans; Ibuprofen; M | 1978 |
Aspirin hepatotoxicity and disseminated intravascular coagulation.
Topics: Adolescent; Arthritis, Juvenile; Aspirin; Biopsy; Chemical and Drug Induced Liver Injury; Disseminat | 1977 |
Lymphopenia and hepatic toxicity with ibuprofen.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Child; Fe | 1977 |
A novel biologically active seleno-organic compound--VI. Protection by ebselen (PZ 51) against galactosamine/endotoxin-induced hepatitis in mice.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azoles; Chemical and Drug Induced Liver | 1986 |
Acute intoxication due to ibuprofen overdose.
Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; I | 1986 |