Page last updated: 2024-10-28

ibuprofen and Acute Kidney Tubular Necrosis

ibuprofen has been researched along with Acute Kidney Tubular Necrosis in 10 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Research Excerpts

ExcerptRelevanceReference
"Ibuprofen-associated, acute, reversible renal failure with hyperkalemia, tubular necrosis, and proteinuria developed in a patient who had no predisposing underlying disease."7.67Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria. ( Azziz-Baumgartner, R; Eldredge, CJ; Gikas, PW; Hyzy, R; Marasco, WA; Stross, J, 1987)
"A nonsteroid antiinflammatory agent (Ibuprofen) was used in a controlled randomized study to determine its ability to replace steroids in the prophylaxis of cadaveric kidney rejection."5.05Nonsteroid antiinflammatory agents as a substitute treatment for steroids in ATGAM-treated cadaver kidney recipients. ( Chatenoud, L; Chkoff, N; Crosnier, J; Descamps, JM; Droz, D; Kreis, H; Lacombe, M; Noel, LH; Tolani, M, 1984)
"Pretreatment with the thromboxane synthase inhibitor OKY-046 but not the cyclo-oxygenase inhibitor ibuprofen protects against ischemia-induced acute tubular necrosis."3.67A high plasma prostaglandin to thromboxane ratio protects against renal ischemia. ( Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR, 1987)
"Ibuprofen-associated, acute, reversible renal failure with hyperkalemia, tubular necrosis, and proteinuria developed in a patient who had no predisposing underlying disease."3.67Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria. ( Azziz-Baumgartner, R; Eldredge, CJ; Gikas, PW; Hyzy, R; Marasco, WA; Stross, J, 1987)
"The patient discussed developed severe acute renal failure after strenuous exercise and therapeutic doses of ibuprofen and hydrochlorothiazide-triamterene."1.29Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene. ( Sanders, LR, 1995)
"However, the major mechanism for the acute renal failure was thought to be related to inhibition of renal prostaglandin synthesis in the face of compromised renal hemodynamics secondary to alcohol-induced volume depletion."1.28Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs. ( Iliopoulos, O; Oberley, TD; Parthasarathy, R; Wen, SF, 1992)
"2 patients with systemic lupus erythematosus and mild renal functional impairment were treated with ibuprofen, one of the phenylproprionic nonsteroidal anti-inflammatory drugs."1.26Ibuprofen-induced acute renal failure with acute tubular necrosis. ( Cohen, AH; Fong, HJ, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kreis, H1
Chkoff, N1
Droz, D1
Noel, LH1
Tolani, M1
Descamps, JM1
Chatenoud, L1
Lacombe, M1
Crosnier, J1
Fong, HJ1
Cohen, AH1
Sanders, LR1
Schilling, M1
Saunder, A1
Southard, JH1
Belzer, FO1
Wen, SF1
Parthasarathy, R1
Iliopoulos, O1
Oberley, TD1
Perazella, MA1
Buller, GK1
Kaufman, RP2
Anner, H2
Kobzik, L2
Valeri, CR2
Shepro, D2
Hechtman, HB2
Blau, EB1
Marasco, WA1
Gikas, PW1
Azziz-Baumgartner, R1
Hyzy, R1
Eldredge, CJ1
Stross, J1

Trials

1 trial available for ibuprofen and Acute Kidney Tubular Necrosis

ArticleYear
Nonsteroid antiinflammatory agents as a substitute treatment for steroids in ATGAM-treated cadaver kidney recipients.
    Transplantation, 1984, Volume: 37, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antilymphocyte Serum; Cadaver; Female; Graf

1984

Other Studies

9 other studies available for ibuprofen and Acute Kidney Tubular Necrosis

ArticleYear
Ibuprofen-induced acute renal failure with acute tubular necrosis.
    American journal of nephrology, 1982, Volume: 2, Issue:1

    Topics: Acute Kidney Injury; Adult; Biopsy; Female; Humans; Ibuprofen; Kidney Glomerulus; Kidney Tubular Nec

1982
Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:12

    Topics: Acute Kidney Injury; Catecholamines; Cytokines; Eicosanoids; Hormones; Hydrochlorothiazide; Hyperten

1995
Long-term renal preservation and prevention of acute tubular necrosis by inhibition of arachidonate metabolism.
    Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera, 1995, Issue:4

    Topics: Adenosine; Allopurinol; Animals; Arachidonic Acid; Aspirin; Benzofurans; Dogs; Enzyme Inhibitors; Fe

1995
Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1992, Volume: 20, Issue:3

    Topics: Acute Kidney Injury; Adult; Alcoholic Intoxication; Anti-Inflammatory Agents, Non-Steroidal; Aspirin

1992
Can ibuprofen cause acute renal failure in a normal individual? A case of acute overdose.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:5

    Topics: Drug Overdose; Female; Humans; Ibuprofen; Kidney Tubular Necrosis, Acute; Middle Aged; Urine

1991
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprof

1987
Ibuprofen and ethanol overdose-induced acute tubular necrosis.
    Wisconsin medical journal, 1987, Volume: 86, Issue:9

    Topics: Acute Kidney Injury; Adolescent; Alcoholic Intoxication; Animals; Cricetinae; Humans; Ibuprofen; Kid

1987
Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria.
    Archives of internal medicine, 1987, Volume: 147, Issue:12

    Topics: Acute Kidney Injury; Biomechanical Phenomena; Biopsy; Humans; Hyperkalemia; Ibuprofen; Kidney; Kidne

1987
Vasodilator prostaglandins (PG) prevent renal damage after ischemia.
    Annals of surgery, 1987, Volume: 205, Issue:2

    Topics: Acute Kidney Injury; Animals; Dopamine; Ibuprofen; Ischemia; Kidney; Kidney Tubular Necrosis, Acute;

1987