ibuprofen has been researched along with Acute Kidney Injury in 90 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "High-dose ibuprofen (IBU) may slow the decline of lung function in patients with cystic fibrosis (CF), but its use has been limited due to concerns over renal and gastrointestinal toxicity." | 9.19 | High-dose ibuprofen is not associated with increased biomarkers of kidney injury in patients with cystic fibrosis. ( Diehl, S; Ferguson, M; Guillet, A; Lahiri, T, 2014) |
| "The aim was to assess whether using LSPS matching would enable the evaluation of paracetamol, compared to ibuprofen, and increased risk of myocardial infarction, stroke, gastrointestinal (GI) bleeding, or acute renal failure." | 7.96 | Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen. ( Berlin, JA; Fife, D; Ryan, PB; Schuemie, MJ; Swerdel, J; Weinstein, RB, 2020) |
| " We assessed the impact of ibuprofen exposure on renal function among dehydrated children with acute gastroenteritis (AGE) to further characterize NSAID-associated AKI." | 7.81 | Ibuprofen-associated acute kidney injury in dehydrated children with acute gastroenteritis. ( Balestracci, A; Elmo, ME; Ezquer, M; Molini, A; Thorel, C; Toledo, I; Torrents, M, 2015) |
| "Ibuprofen and acetaminophen are frequently alternated or simultaneously used to treat fever or pain in children, while the evidence for the safety of such a combination is lacking." | 7.80 | Association between an excess risk of acute kidney injury and concomitant use of ibuprofen and acetaminophen in children, retrospective analysis of a spontaneous reporting system. ( Jiang, P; Sun, H; Wu, J; Yue, Z, 2014) |
| "Ibuprofen-associated, acute, reversible renal failure with hyperkalemia, tubular necrosis, and proteinuria developed in a patient who had no predisposing underlying disease." | 7.67 | Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria. ( Azziz-Baumgartner, R; Eldredge, CJ; Gikas, PW; Hyzy, R; Marasco, WA; Stross, J, 1987) |
| "Ibuprofen use was associated with a statistically significantly increased risk of hospital-acquired AKI (hazard ratio [HR], 1." | 5.62 | Association of Ibuprofen Prescription With Acute Kidney Injury Among Hospitalized Children in China. ( Cao, Y; Chen, R; Gao, Q; Li, Y; Luo, F; Nie, S; Su, L; Xu, R; Xu, X, 2021) |
| "In many parts of Europe, nephropathia epidemica (NE) is an endemic zoonosis." | 5.38 | Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica. ( Leicht-Biener, U; Mucsi, I; Seitz, K; Wagner, R, 2012) |
| "Metformin is an antihyperglycemic agent commonly used in diabetic patients." | 5.37 | The nephrologist's role in metformin-induced lactic acidosis. ( Basterrechea, MA; de Arriba, G; Gómez-Navarro, L; Hernández-Sevillano, B; Pérez del Valle, KM; Rodríguez-Palomares, JR; Sánchez-Heras, M; Tallón, S; Torres-Guinea, M, 2011) |
| "Changes in renal biomarkers suggest mild acute kidney injury and reduced kidney function during a single bout of endurance cycling in the heat, without influence from moderate ibuprofen ingestion." | 5.27 | Renal stress and kidney injury biomarkers in response to endurance cycling in the heat with and without ibuprofen. ( Armstrong, LE; Butts, CL; Caldwell, AR; Ganio, MS; Kunces, LJ; Lee, EC; McDermott, BP; Munoz, CX; Smith, CR; Vingren, JL; Williamson, K, 2018) |
| "High-dose ibuprofen (IBU) may slow the decline of lung function in patients with cystic fibrosis (CF), but its use has been limited due to concerns over renal and gastrointestinal toxicity." | 5.19 | High-dose ibuprofen is not associated with increased biomarkers of kidney injury in patients with cystic fibrosis. ( Diehl, S; Ferguson, M; Guillet, A; Lahiri, T, 2014) |
| " Spironolactone, furosemide, and trimethoprim with sulfamethoxazole are medicines that, in particular, need to be used carefully and monitored closely in patients in the community at risk of acute kidney injury." | 4.12 | Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care. ( Kassie, GM; Kerr, M; Moffat, A; Pratt, N; Roughead, EE, 2022) |
| "The aim was to assess whether using LSPS matching would enable the evaluation of paracetamol, compared to ibuprofen, and increased risk of myocardial infarction, stroke, gastrointestinal (GI) bleeding, or acute renal failure." | 3.96 | Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen. ( Berlin, JA; Fife, D; Ryan, PB; Schuemie, MJ; Swerdel, J; Weinstein, RB, 2020) |
| " We assessed the impact of ibuprofen exposure on renal function among dehydrated children with acute gastroenteritis (AGE) to further characterize NSAID-associated AKI." | 3.81 | Ibuprofen-associated acute kidney injury in dehydrated children with acute gastroenteritis. ( Balestracci, A; Elmo, ME; Ezquer, M; Molini, A; Thorel, C; Toledo, I; Torrents, M, 2015) |
| "Ibuprofen and acetaminophen are frequently alternated or simultaneously used to treat fever or pain in children, while the evidence for the safety of such a combination is lacking." | 3.80 | Association between an excess risk of acute kidney injury and concomitant use of ibuprofen and acetaminophen in children, retrospective analysis of a spontaneous reporting system. ( Jiang, P; Sun, H; Wu, J; Yue, Z, 2014) |
| "To investigate the incidence of acute kidney injury after cardiac surgery and its association with mortality in a patient population receiving ibuprofen and gentamicin perioperatively." | 3.80 | Acute kidney injury is independently associated with higher mortality after cardiac surgery. ( Jensen, ME; Kandler, K; Møller, CH; Nilsson, JC; Steinbrüchel, DA, 2014) |
| "The risk of a newly diagnosed episode of upper gastrointestinal bleeding, acute liver and renal failure, agranulocytosis, aplastic anemia, severe skin disorders, and anaphylaxis was examined within 30 days after the first prescription for a low dose of diclofenac, naproxen, or ibuprofen in a cohort in the United Kingdom." | 3.70 | Low-dose diclofenac, naproxen, and ibuprofen cohort study. ( Duque-Oliart, A; García-Rodríguez, LA; Pérez-Gutthann, S; Varas-Lorenzo, C, 1999) |
| "Ibuprofen-associated, acute, reversible renal failure with hyperkalemia, tubular necrosis, and proteinuria developed in a patient who had no predisposing underlying disease." | 3.67 | Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria. ( Azziz-Baumgartner, R; Eldredge, CJ; Gikas, PW; Hyzy, R; Marasco, WA; Stross, J, 1987) |
| "Acute renal failure, vomiting, and melena developed in a 10-month-old dog after ingestion of ten 600-mg tablets of ibuprofen." | 3.67 | Ibuprofen toxicosis in a dog. ( Bacia, JJ; Barsanti, JA; Brown, SA; Spyridakis, LK, 1986) |
| " However, adverse effects should be taken into account in the choice between ibuprofen and acetaminophen." | 2.44 | [Ibuprofen in childhood: evidence-based review of efficacy and safety]. ( Cosson, MA; Landre-Peigne, C; Leroy, S; Mosca, A; Pons, G, 2007) |
| "Acute renal failure is commonly seen in adults after treatment with nonsteroidal antiinflammatory agents." | 2.40 | Acute nonoliguric renal failure in children associated with nonsteroidal antiinflammatory agents. ( Kaplan, BS; Schaller, S, 1998) |
| "Ibuprofen has recently been introduced as over-the-counter drug in several countries." | 2.38 | Ibuprofen as an over-the-counter drug: is there a risk for renal injury? ( Brune, K; Goerig, M; Luft, FC; Mann, JF, 1993) |
| " However, higher bioavailability would increase the danger of renal injury caused by oxidative stress." | 1.72 | Mechanochemical prepared ibuprofen- ( Gu, X; Jin, K; Mao, L; Pu, F; Su, W; Xie, Z; Xu, W; Yang, J, 2022) |
| "Ibuprofen use was associated with a statistically significantly increased risk of hospital-acquired AKI (hazard ratio [HR], 1." | 1.62 | Association of Ibuprofen Prescription With Acute Kidney Injury Among Hospitalized Children in China. ( Cao, Y; Chen, R; Gao, Q; Li, Y; Luo, F; Nie, S; Su, L; Xu, R; Xu, X, 2021) |
| "Acute tubulointerstitial nephritis (ATIN) is a rare entity in the pediatric age." | 1.46 | [Acute renal damage secondary to acute tubulointerstitial nephritis drug use. Case report]. ( Álvarez Blanco, O; Barraca Nuñez, D; Butragueño Laiseca, L; Martínez López, AB; Molina Molina, MDC; Oikonomopoulou, N; Urbano Villaescusa, J, 2017) |
| "In many parts of Europe, nephropathia epidemica (NE) is an endemic zoonosis." | 1.38 | Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica. ( Leicht-Biener, U; Mucsi, I; Seitz, K; Wagner, R, 2012) |
| "Metformin is an antihyperglycemic agent commonly used in diabetic patients." | 1.37 | The nephrologist's role in metformin-induced lactic acidosis. ( Basterrechea, MA; de Arriba, G; Gómez-Navarro, L; Hernández-Sevillano, B; Pérez del Valle, KM; Rodríguez-Palomares, JR; Sánchez-Heras, M; Tallón, S; Torres-Guinea, M, 2011) |
| " Appropriate dosing and managing of these drugs do not likely lead to organ toxicity." | 1.35 | Acute non-oliguric kidney failure and cholestatic hepatitis induced by ibuprofen and acetaminophen: a case report. ( Angeli, S; Brugnara, M; Cuzzolin, L; Zaffanello, M, 2009) |
| "Fatal acute renal failure from ibuprofen has never been reported." | 1.30 | Near-fatal but reversible acute renal failure after massive ibuprofen ingestion. ( Brod-Miller, C; Mattana, J; Perinbasekar, S, 1997) |
| " Although this study failed to describe a dose-response relationship, it appears that there are significant breed differences in susceptibility to GIU subsequent to ibuprofen exposure." | 1.30 | A case-control study of acute ibuprofen toxicity in dogs. ( Hungerford, LL; Poortinga, EW, 1998) |
| "We report an NSAID-induced form of acute renal failure that represents a dual mechanism of impact on renal function involving direct parenchymal damage at a renal papillary level and mechanical outflow ureteric obstruction consequent to acute papillary necrosis." | 1.30 | Acute renal papillary necrosis induced by ibuprofen. ( Atta, MG; Whelton, A, 1997) |
| "The patient discussed developed severe acute renal failure after strenuous exercise and therapeutic doses of ibuprofen and hydrochlorothiazide-triamterene." | 1.29 | Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene. ( Sanders, LR, 1995) |
| "Acute renal insufficiency is a rare, reversible effect of ibuprofen overdose documented in adults, but we could find no published pediatric cases." | 1.29 | Acute renal insufficiency in ibuprofen overdose. ( Gazarian, M; Johnson, D; Kim, J; Verjee, Z, 1995) |
| "However, the major mechanism for the acute renal failure was thought to be related to inhibition of renal prostaglandin synthesis in the face of compromised renal hemodynamics secondary to alcohol-induced volume depletion." | 1.28 | Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs. ( Iliopoulos, O; Oberley, TD; Parthasarathy, R; Wen, SF, 1992) |
| " Electrolytes, blood urea nitrogen, and serum creatinine levels need to be monitored in high-risk patients with predisposing factors and for chronic, long-term use of drugs that inhibit prostaglandin synthesis." | 1.27 | Reversible renal failure associated with ibuprofen: case report and review of the literature. ( Poirier, TI, 1984) |
| "Pretreatment with ibuprofen (n = 10) (12 mg/kg) or OKY 046 and ibuprofen (n = 9) inhibited TxB2 and 6-keto-PGF1 alpha synthesis, but creatinine levels and renal weight rose (p less than 0." | 1.27 | Prostacyclin and thromboxane A2 moderate postischemic renal failure. ( Alexander, F; Hechtman, HB; Kobzik, L; Lelcuk, S; Shepro, D; Valeri, CR, 1985) |
| "2 patients with systemic lupus erythematosus and mild renal functional impairment were treated with ibuprofen, one of the phenylproprionic nonsteroidal anti-inflammatory drugs." | 1.26 | Ibuprofen-induced acute renal failure with acute tubular necrosis. ( Cohen, AH; Fong, HJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (33.33) | 18.7374 |
| 1990's | 22 (24.44) | 18.2507 |
| 2000's | 11 (12.22) | 29.6817 |
| 2010's | 18 (20.00) | 24.3611 |
| 2020's | 9 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martini, S | 1 |
| Vitali, F | 1 |
| Capelli, I | 1 |
| Donadei, C | 1 |
| Raschi, E | 1 |
| Aiello, V | 1 |
| Corvaglia, L | 1 |
| De Ponti, F | 1 |
| Poluzzi, E | 1 |
| Galletti, S | 1 |
| Xu, W | 1 |
| Yang, J | 1 |
| Gu, X | 1 |
| Su, W | 2 |
| Pu, F | 1 |
| Xie, Z | 1 |
| Jin, K | 1 |
| Mao, L | 1 |
| Mittal, A | 1 |
| Tamer, P | 1 |
| Shah, I | 1 |
| Cortes, A | 1 |
| Hinman, AD | 1 |
| Roughead, EE | 1 |
| Kerr, M | 1 |
| Moffat, A | 1 |
| Kassie, GM | 1 |
| Pratt, N | 1 |
| Hebert, JF | 1 |
| Eiwaz, MB | 1 |
| Nickerson, MN | 1 |
| Munhall, AC | 1 |
| Pai, AA | 1 |
| Groat, T | 1 |
| Andeen, NK | 1 |
| Hutchens, MP | 1 |
| Weinstein, RB | 1 |
| Ryan, PB | 1 |
| Berlin, JA | 1 |
| Schuemie, MJ | 1 |
| Swerdel, J | 1 |
| Fife, D | 1 |
| Prieto-García, L | 1 |
| Vicente-Vicente, L | 1 |
| Blanco-Gozalo, V | 1 |
| Hidalgo-Thomas, O | 1 |
| García-Macías, MC | 1 |
| Kurtz, A | 1 |
| Layton, AT | 1 |
| Sanz, AB | 1 |
| Morales, AI | 1 |
| Martínez-Salgado, C | 1 |
| Pericacho, M | 1 |
| Sancho-Martínez, SM | 1 |
| López-Hernández, FJ | 1 |
| Su, L | 1 |
| Li, Y | 1 |
| Xu, R | 1 |
| Luo, F | 1 |
| Gao, Q | 1 |
| Chen, R | 1 |
| Cao, Y | 1 |
| Nie, S | 1 |
| Xu, X | 1 |
| Yurttutan, S | 1 |
| Gullu, UU | 1 |
| Lipman, GS | 1 |
| Shea, K | 1 |
| Christensen, M | 1 |
| Phillips, C | 1 |
| Burns, P | 1 |
| Higbee, R | 1 |
| Koskenoja, V | 1 |
| Eifling, K | 1 |
| Krabak, BJ | 1 |
| Oikonomopoulou, N | 1 |
| Martínez López, AB | 1 |
| Urbano Villaescusa, J | 1 |
| Molina Molina, MDC | 1 |
| Butragueño Laiseca, L | 1 |
| Barraca Nuñez, D | 1 |
| Álvarez Blanco, O | 1 |
| McDermott, BP | 1 |
| Smith, CR | 1 |
| Butts, CL | 1 |
| Caldwell, AR | 1 |
| Lee, EC | 1 |
| Vingren, JL | 1 |
| Munoz, CX | 1 |
| Kunces, LJ | 1 |
| Williamson, K | 1 |
| Ganio, MS | 1 |
| Armstrong, LE | 1 |
| Uber, AM | 1 |
| Montez-Rath, ME | 1 |
| Kwiatkowski, DM | 1 |
| Krawczeski, CD | 1 |
| Sutherland, SM | 1 |
| Zajic, SC | 1 |
| Jarvis, JP | 1 |
| Zhang, P | 1 |
| Rajula, KD | 1 |
| Brangan, A | 1 |
| Brenner, R | 1 |
| Dempsey, MP | 1 |
| Christman, MF | 1 |
| Platts-Mills, TF | 1 |
| Richmond, NL | 1 |
| Hunold, KM | 1 |
| Bowling, CB | 1 |
| Lahiri, T | 1 |
| Guillet, A | 1 |
| Diehl, S | 1 |
| Ferguson, M | 1 |
| Lohiya, GS | 2 |
| Lohiya, P | 2 |
| Krishna, V | 2 |
| Lohiya, S | 2 |
| Millington, E | 1 |
| Yue, Z | 1 |
| Jiang, P | 1 |
| Sun, H | 1 |
| Wu, J | 1 |
| Kandler, K | 1 |
| Jensen, ME | 1 |
| Nilsson, JC | 1 |
| Møller, CH | 1 |
| Steinbrüchel, DA | 1 |
| Balestracci, A | 1 |
| Ezquer, M | 1 |
| Elmo, ME | 1 |
| Molini, A | 1 |
| Thorel, C | 1 |
| Torrents, M | 1 |
| Toledo, I | 1 |
| Schmidt, JJ | 1 |
| Ramazan, L | 1 |
| Bockemeyer, C | 1 |
| Günter, HH | 1 |
| Martens-Lobenhoffer, J | 1 |
| Ganzenmüller, T | 1 |
| Bode-Böger, SM | 1 |
| Kielstein, JT | 1 |
| Quiroga, B | 1 |
| Basterrechea, MÁ | 2 |
| Fernández-Francés, J | 1 |
| de Arriba, G | 2 |
| Antonucci, R | 1 |
| Cuzzolin, L | 2 |
| Arceri, A | 1 |
| Dessì, A | 1 |
| Fanos, V | 1 |
| Zaffanello, M | 1 |
| Brugnara, M | 1 |
| Angeli, S | 1 |
| Gómez-Navarro, L | 1 |
| Sánchez-Heras, M | 1 |
| Pérez del Valle, KM | 1 |
| Hernández-Sevillano, B | 1 |
| Tallón, S | 1 |
| Torres-Guinea, M | 1 |
| Rodríguez-Palomares, JR | 1 |
| Wagner, R | 1 |
| Leicht-Biener, U | 1 |
| Mucsi, I | 1 |
| Seitz, K | 1 |
| Geoghegan, P | 1 |
| Sexton, DJ | 1 |
| Giblin, L | 1 |
| O'Regan, A | 1 |
| Singh, AK | 1 |
| Colvin, RB | 1 |
| Ulinski, T | 1 |
| Guigonis, V | 1 |
| Dunan, O | 1 |
| Bensman, A | 1 |
| Moghal, NE | 1 |
| Hegde, S | 1 |
| Eastham, KM | 1 |
| Ting, A | 1 |
| Freund, J | 1 |
| Leroy, S | 1 |
| Mosca, A | 1 |
| Landre-Peigne, C | 1 |
| Cosson, MA | 1 |
| Pons, G | 1 |
| Erdeve, O | 1 |
| Sarici, SU | 1 |
| Sari, E | 1 |
| Gok, F | 1 |
| de la Coussaye, JE | 1 |
| Mourad, G | 1 |
| Canaud, B | 1 |
| Chong, G | 1 |
| Beraud, JJ | 1 |
| Mion, C | 1 |
| Poirier, TI | 1 |
| Dahlin, PA | 1 |
| George, J | 1 |
| Androsova, SO | 1 |
| Kutyrina, IM | 1 |
| Trèves, R | 1 |
| Gastine, H | 1 |
| Richard, A | 1 |
| Hugon, J | 1 |
| Varnoux, M | 1 |
| Gay, R | 1 |
| Desproges-Gotteron, R | 1 |
| Blackshear, JL | 1 |
| Davidman, M | 1 |
| Stillman, MT | 1 |
| Regester, RF | 1 |
| Zawada, ET | 1 |
| Wachtel, A | 1 |
| de Torrenté, A | 1 |
| Fong, HJ | 1 |
| Cohen, AH | 1 |
| Herrick, RT | 1 |
| Sheiner, PA | 1 |
| Mor, E | 1 |
| Chodoff, L | 1 |
| Glabman, S | 1 |
| Emre, S | 1 |
| Schwartz, ME | 1 |
| Miller, CM | 1 |
| Sanders, LR | 1 |
| Kim, J | 1 |
| Gazarian, M | 1 |
| Verjee, Z | 1 |
| Johnson, D | 1 |
| Chen, CY | 1 |
| Pang, VF | 1 |
| Chen, CS | 1 |
| Le, HT | 1 |
| Bosse, GM | 1 |
| Tsai, Y | 1 |
| Wattad, A | 1 |
| Feehan, T | 1 |
| Shepard, FM | 1 |
| Youngberg, G | 1 |
| Mann, JF | 1 |
| Goerig, M | 1 |
| Brune, K | 1 |
| Luft, FC | 1 |
| Mattana, J | 1 |
| Perinbasekar, S | 1 |
| Brod-Miller, C | 1 |
| Primack, WA | 1 |
| Rahman, SM | 1 |
| Pullman, J | 1 |
| Ramachandran, S | 1 |
| Giles, PD | 1 |
| Hartland, A | 1 |
| Sivarajan, M | 1 |
| Wasse, L | 1 |
| Hancock, EW | 1 |
| Poortinga, EW | 1 |
| Hungerford, LL | 1 |
| Bhowmik, D | 1 |
| Schaller, S | 1 |
| Kaplan, BS | 1 |
| Pérez-Gutthann, S | 1 |
| García-Rodríguez, LA | 1 |
| Duque-Oliart, A | 1 |
| Varas-Lorenzo, C | 1 |
| Atta, MG | 1 |
| Whelton, A | 1 |
| Del Vecchio, MT | 1 |
| Sundel, ER | 1 |
| Rosefsky, JB | 1 |
| Wong, W | 1 |
| Coward, RJ | 1 |
| Morris, MC | 1 |
| Kimberly, RP | 1 |
| Sherman, RL | 1 |
| Mouradian, J | 1 |
| Lockshin, MD | 1 |
| Brandstetter, RD | 1 |
| Mar, DD | 1 |
| Wen, SF | 1 |
| Parthasarathy, R | 1 |
| Iliopoulos, O | 1 |
| Oberley, TD | 1 |
| Hall, AH | 1 |
| Smolinske, SC | 1 |
| Stover, B | 1 |
| Conrad, FL | 1 |
| Rumack, BH | 1 |
| Spierto, RJ | 1 |
| Kaufman, MB | 1 |
| Stoukides, CA | 1 |
| Murray, MD | 1 |
| Brater, DC | 1 |
| Tierney, WM | 1 |
| Hui, SL | 1 |
| McDonald, CJ | 1 |
| Klausner, JM | 1 |
| Paterson, IS | 1 |
| Kobzik, L | 3 |
| Rodzen, C | 1 |
| Valeri, CR | 3 |
| Shepro, D | 3 |
| Hechtman, HB | 3 |
| van Biljon, G | 1 |
| Rogers, SY | 1 |
| Venning, MC | 1 |
| Atkinson, LK | 1 |
| Goodship, TH | 1 |
| Ward, MK | 1 |
| Elsasser, GN | 1 |
| Lopez, L | 1 |
| Evans, E | 1 |
| Barone, EJ | 1 |
| ter Borg, EJ | 1 |
| de Jong, PE | 1 |
| Meyer, S | 1 |
| van Rijswijk, MH | 1 |
| Kallenberg, CG | 1 |
| Blau, EB | 1 |
| Marasco, WA | 1 |
| Gikas, PW | 1 |
| Azziz-Baumgartner, R | 1 |
| Hyzy, R | 1 |
| Eldredge, CJ | 1 |
| Stross, J | 1 |
| Moss, AH | 1 |
| Riley, R | 1 |
| Murgo, A | 1 |
| Skaff, LA | 1 |
| Lee, CY | 1 |
| Finkler, A | 1 |
| Spyridakis, LK | 1 |
| Bacia, JJ | 1 |
| Barsanti, JA | 1 |
| Brown, SA | 1 |
| Kaufman, RP | 1 |
| Anner, H | 1 |
| Lelcuk, S | 1 |
| Alexander, F | 1 |
| Reeves, WB | 1 |
| Foley, RJ | 1 |
| Weinman, EJ | 1 |
| Bennett, RR | 1 |
| Dunkelberg, JC | 1 |
| Marks, ES | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Non-steroidal Anti-inflammatory Affect on Kidneys in Endurance Distances[NCT02272725] | Phase 3 | 91 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The participants experiencing acute kidney injury (diagnosed by an increase in creatinine of greater or equal to 1.5x that of estimated baseline creatinine from age and weight) will be from measured point-of-care blood test of the finish line immediately following the completion of a 50 mile ultramarathon. This outcome measure is a biochemical reading, that may not necessarily be a clinical adverse event. (NCT02272725)
Timeframe: participants will be followed through the duration of a 50 mile ultramarathon, an expected average of 18 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo | 16 |
| Ibuprofen | 22 |
The count of participants experiencing exercise-associated hyponatremia (defined as < 135 mEq) will be estimated from measured point-of-care blood test at the finish line immediately following completion of a 50 mile ultramarathon. This outcome measure is a biochemical reading, that may not necessarily be a clinical adverse event. (NCT02272725)
Timeframe: participants will be followed through the duration of a 50 mile ultramarathon, an expected average of 18 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo | 7 |
| Ibuprofen | 3 |
A Borg score of perceived exertion will be measured at the finish line immediately following completion of a 50 mile ultramarathon to measure what affect ibuprofen had on perceived exertion as analgesia may have made the endurance event perceived as less exertional. Scores range from 7 - 20, with higher scores indicative of greater amount of exertion. (NCT02272725)
Timeframe: participants will be followed through the duration of a 50 mile ultramarathon, an expected average of 18 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 15.96 |
| Ibuprofen | 15.99 |
4 reviews available for ibuprofen and Acute Kidney Injury
| Article | Year |
|---|---|
[Ibuprofen in childhood: evidence-based review of efficacy and safety].
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chickenpox; Child; Gastrointes | 2007 |
Renal consequences of nonsteroidal antiinflammatory drugs.
Topics: Acidosis; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Bartter Syndrome; Female; Humans; Hyp | 1982 |
Ibuprofen as an over-the-counter drug: is there a risk for renal injury?
Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Child; Dose-Response Rela | 1993 |
Acute nonoliguric renal failure in children associated with nonsteroidal antiinflammatory agents.
Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child, Preschool; F | 1998 |
3 trials available for ibuprofen and Acute Kidney Injury
| Article | Year |
|---|---|
Ibuprofen versus placebo effect on acute kidney injury in ultramarathons: a randomised controlled trial.
Topics: Acute Kidney Injury; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Incidence; Logistic Mode | 2017 |
Renal stress and kidney injury biomarkers in response to endurance cycling in the heat with and without ibuprofen.
Topics: Acute Kidney Injury; Adult; Bicycling; Biomarkers; Creatinine; Double-Blind Method; Female; Hot Temp | 2018 |
High-dose ibuprofen is not associated with increased biomarkers of kidney injury in patients with cystic fibrosis.
Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Child; | 2014 |
83 other studies available for ibuprofen and Acute Kidney Injury
| Article | Year |
|---|---|
Impact of nephrotoxic drugs on urinary biomarkers of renal function in very preterm infants.
Topics: Acute Kidney Injury; Amikacin; Biomarkers; Female; Humans; Ibuprofen; Infant; Infant, Newborn; Infan | 2022 |
Mechanochemical prepared ibuprofen-
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bacterial Outer Membrane Prot | 2022 |
Postoperative Acute Kidney Injury With Dual NSAID Use After Outpatient Primary Total Joint Arthroplasty.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Aspiri | 2022 |
Medicine-Induced Acute Kidney Injury Findings from Spontaneous Reporting Systems, Sequence Symmetry Analysis and a Case-Control Study with a Focus on Medicines Used in Primary Care.
Topics: Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Amlodipine; Amphotericin B; Australia; | 2022 |
Legal Performance-enhancing Drugs Alter Course and Treatment of Rhabdomyolysis-induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Caffeine; Cilastatin; Glycerol; Humans; Ibuprofen; Mice; Performance-E | 2023 |
Channeling Bias in the Analysis of Risk of Myocardial Infarction, Stroke, Gastrointestinal Bleeding, and Acute Renal Failure with the Use of Paracetamol Compared with Ibuprofen.
Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Ag | 2020 |
Pathophysiological mechanisms underlying a rat model of triple whammy acute kidney injury.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, No | 2020 |
Association of Ibuprofen Prescription With Acute Kidney Injury Among Hospitalized Children in China.
Topics: Acute Kidney Injury; Adolescent; Child; Child, Preschool; China; Cohort Studies; Female; Hospitaliza | 2021 |
Neonatal AKI in late preterm infants with patent ductus arteriosus.
Topics: Acute Kidney Injury; Ductus Arteriosus, Patent; Humans; Ibuprofen; Infant; Infant, Newborn; Infant, | 2021 |
[Acute renal damage secondary to acute tubulointerstitial nephritis drug use. Case report].
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Infant; Nep | 2017 |
Nephrotoxin exposure and acute kidney injury in critically ill children undergoing congenital cardiac surgery.
Topics: Acute Kidney Injury; Adolescent; Aspirin; Cardiac Surgical Procedures; Child; Child, Preschool; Crit | 2018 |
Individuals with CYP2C8 and CYP2C9 reduced metabolism haplotypes self-adjusted ibuprofen dose in the Coriell Personalized Medicine Collaborative.
Topics: Acute Kidney Injury; Adult; Aged; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Female; Genotype | 2019 |
Life-threatening hyperkalemia after 2 days of ibuprofen.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hyperkalemia; Ib | 2013 |
Death related to Ibuprofen, valdecoxib, and medical errors: case report and medicolegal issues.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Contusions; Fatal Outcome; Fema | 2013 |
Death related to Ibuprofen, valdecoxib, and medical errors: case report and medicolegal issues.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Female; Food Industry; Humans; Ibuprof | 2013 |
Authors' reply: NSAIDs and small kidneys in a workers' compensation death claim.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Female; Food Industry; Humans; Ibuprof | 2013 |
Association between an excess risk of acute kidney injury and concomitant use of ibuprofen and acetaminophen in children, retrospective analysis of a spontaneous reporting system.
Topics: Acetaminophen; Acute Kidney Injury; Adverse Drug Reaction Reporting Systems; Analgesics, Non-Narcoti | 2014 |
Acute kidney injury is independently associated with higher mortality after cardiac surgery.
Topics: Acute Kidney Injury; Aged; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Bacterial Agents; Ca | 2014 |
Ibuprofen-associated acute kidney injury in dehydrated children with acute gastroenteritis.
Topics: Acute Kidney Injury; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Argentina; Child; Child, P | 2015 |
Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.
Topics: Acute Disease; Acute Kidney Injury; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
Diffuse alveolar damage and acute kidney injury induced by abusive use of non-steroidal anti-inflammatory drugs: a new and atypical renopulmonary syndrome?
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Hemorrhage; Humans; Ibu | 2016 |
Changes in urinary PGE2 after ibuprofen treatment in preterm infants with patent ductus arteriosus.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Dinoprostone; Ductus Arter | 2009 |
Acute non-oliguric kidney failure and cholestatic hepatitis induced by ibuprofen and acetaminophen: a case report.
Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury | 2009 |
The nephrologist's role in metformin-induced lactic acidosis.
Topics: Acidosis, Lactic; Acute Kidney Injury; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibi | 2011 |
Ibuprofen or diclofenac is associated with more severe acute kidney injury in nephropathia epidemica.
Topics: Acetaminophen; Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C | 2012 |
Taught a lesson by taut skin.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroid | 2012 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-2003. A 68-year-old woman with impaired renal function.
Topics: Acute Kidney Injury; Aged; Biopsy; Diagnosis, Differential; Female; Granuloma; Humans; Hypertension; | 2003 |
Acute renal failure after treatment with non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Causality; Child; Child, P | 2004 |
Ibuprofen and acute renal failure in a toddler.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Follow-Up Studies; Humans; Ibuprofen; | 2004 |
Nonsteroidal antiinflammatory-induced acute renal failure detected on bone scintigraphy.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Bone and Bones; Diclofenac; Humans; Ib | 2004 |
Oral-ibuprofen-induced acute renal failure in a preterm infant.
Topics: Acute Kidney Injury; Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; | 2008 |
[Acute renal insufficiency and recurrent thrombopenia caused by crossed intolerance to ibuprofen and fenoprofen].
Topics: Acute Kidney Injury; Aged; Fenoprofen; Humans; Ibuprofen; Male; Phenylpropionates; Recurrence; Throm | 1983 |
Reversible renal failure associated with ibuprofen: case report and review of the literature.
Topics: Acute Kidney Injury; Aged; Blood Urea Nitrogen; Carbon Dioxide; Creatinine; Female; Furosemide; Huma | 1984 |
Baclofen toxicity associated with declining renal clearance after ibuprofen.
Topics: Acute Kidney Injury; Baclofen; Humans; Ibuprofen; Male; Mental Disorders; Middle Aged | 1984 |
[Reversible acute renal failure caused by brufen].
Topics: Acute Kidney Injury; Aged; Female; Fenoprofen; Furosemide; Humans; Ibuprofen; Kidney Failure, Chroni | 1984 |
[Aseptic meningitis and acute renal failure induced by ibuprofen during the treatment of systemic lupus erythematosus].
Topics: Acute Kidney Injury; Female; Humans; Ibuprofen; Lupus Erythematosus, Systemic; Meningitis; Meningiti | 1983 |
Identification of risk for renal insufficiency from nonsteroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Age Factors; Aged; Anti-Inflammatory Agents; Arteriosclerosis; Blood Ure | 1983 |
Nephrotic syndrome and renal failure associated with use of nonsteroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female; Fenoprofen; Humans; Ibup | 1980 |
Nonsteroidal anti-inflammatory agents and acute renal failure.
Topics: Acute Kidney Injury; Aged; Female; Humans; Ibuprofen | 1982 |
[Non steroidal anti-inflammatory drugs and acute renal failure (author's transl)].
Topics: Acute Kidney Injury; Aged; Drug Interactions; Female; Humans; Ibuprofen; Kidney; Prostaglandins | 1982 |
Ibuprofen-induced acute renal failure with acute tubular necrosis.
Topics: Acute Kidney Injury; Adult; Biopsy; Female; Humans; Ibuprofen; Kidney Glomerulus; Kidney Tubular Nec | 1982 |
Reversible renal failure due to ibuprofen.
Topics: Acute Kidney Injury; Humans; Ibuprofen; Male; Middle Aged | 1980 |
Acute renal failure associated with the use of ibuprofen in two liver transplant recipients on FK506.
Topics: Acute Kidney Injury; Adolescent; Drug Synergism; Female; Graft Rejection; Humans; Ibuprofen; Liver T | 1994 |
Exercise-induced acute renal failure associated with ibuprofen, hydrochlorothiazide, and triamterene.
Topics: Acute Kidney Injury; Catecholamines; Cytokines; Eicosanoids; Hormones; Hydrochlorothiazide; Hyperten | 1995 |
Acute renal insufficiency in ibuprofen overdose.
Topics: Acute Kidney Injury; Child, Preschool; Drug Overdose; Humans; Ibuprofen; Male | 1995 |
Nephrotoxicity of non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Biopsy; Chronic Disease; Female; Humans; Ibuprofen; Kidney; Nephritis, I | 1994 |
Assessment of ibuprofen-associated nephrotoxicity in renal dysfunction.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Ibuprofen; Kidney; Male; Rabbits; Stereoisomer | 1994 |
Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.
Topics: Acidosis; Acute Kidney Injury; Adult; Charcoal; Citrates; Citric Acid; Drug Overdose; Humans; Ibupro | 1994 |
A unique complication of nonsteroidal anti-inflammatory drug use.
Topics: Abdominal Pain; Acute Kidney Injury; Adolescent; Female; Humans; Ibuprofen; Nephritis, Interstitial | 1994 |
Near-fatal but reversible acute renal failure after massive ibuprofen ingestion.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Kidney; Male | 1997 |
Acute renal failure associated with amoxicillin and ibuprofen in an 11-year-old boy.
Topics: Acute Kidney Injury; Amoxicillin; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Ibuprofen; | 1997 |
Acute renal failure due to rhabdomyolysis in presence of concurrent ciprofibrate and ibuprofen treatment.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clofibric Acid; Drug Interactio | 1997 |
Perioperative acute renal failure associated with preoperative intake of ibuprofen.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diskectomy; Humans; Ibuprofen; | 1997 |
Normal ECG or peaked T waves?
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diabetes Mell | 1998 |
A case-control study of acute ibuprofen toxicity in dogs.
Topics: Acute Kidney Injury; Animals; Case-Control Studies; Dog Diseases; Dogs; Duodenal Ulcer; Female; Gast | 1998 |
Ibuprofen causing acute renal failure in children: reply to Moghal et al.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Ibuprofen; Risk Factors | 1998 |
Low-dose diclofenac, naproxen, and ibuprofen cohort study.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agen | 1999 |
Acute renal papillary necrosis induced by ibuprofen.
Topics: Acute Kidney Injury; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Kidn | 1997 |
Alternating antipyretics: is this an alternative?
Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Drug Synerg | 2001 |
Alternating antipyretics: is this an alternative?
Topics: Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Drug Administration Schedule; Drug Int | 2001 |
Ibuprofen induced acute renal failure in an infant.
Topics: Acute Kidney Injury; Female; Fever; Follow-Up Studies; Humans; Ibuprofen; Infant; Kidney Function Te | 2001 |
Apparent acute renal failure associated with therapeutic aspirin and ibuprofen administration.
Topics: Acute Kidney Injury; Adult; Aspirin; Female; Humans; Ibuprofen; Kidney | 1979 |
Reversible oliguric renal failure associated with ibuprofen treatment.
Topics: Acute Kidney Injury; Aged; Anuria; Humans; Ibuprofen; Male; Oliguria | 1978 |
Acute renal failure following binge drinking and nonsteroidal antiinflammatory drugs.
Topics: Acute Kidney Injury; Adult; Alcoholic Intoxication; Anti-Inflammatory Agents, Non-Steroidal; Aspirin | 1992 |
Ibuprofen overdose in adults.
Topics: Acute Kidney Injury; Adolescent; Adult; Cathartics; Charcoal; Colorado; Drug Overdose; Follow-Up Stu | 1992 |
Acute renal failure associated with the use of over-the-counter ibuprofen.
Topics: Acute Kidney Injury; Age Factors; Aged; Humans; Ibuprofen; Male; Nonprescription Drugs; Risk Factors | 1992 |
Ibuprofen-associated renal impairment in a large general internal medicine practice.
Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Fema | 1990 |
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Creatinine; Disease Models, Animal; Drug | 1989 |
Reversible renal failure associated with ibuprofen in a child. A case report.
Topics: Acute Kidney Injury; Child; Humans; Ibuprofen; Male | 1989 |
Reversible acute renal failure precipitated by overdose of ibuprofen and salbutamol.
Topics: Acute Kidney Injury; Adult; Albuterol; Female; Humans; Ibuprofen | 1986 |
Acute renal failure associated with acute pyelonephritis and consumption of non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Inflammatory Agents; Apazone; Female; Humans; Ibuprofen; Keto | 1986 |
Reversible acute renal failure associated with ibuprofen ingestion and binge drinking.
Topics: Acute Kidney Injury; Adult; Alcohol Drinking; Female; Humans; Ibuprofen | 1988 |
Indomethacin and ibuprofen-induced reversible acute renal failure in a patient with systemic lupus erythematosus.
Topics: Acute Kidney Injury; Female; Humans; Hydrochlorothiazide; Ibuprofen; Indomethacin; Lupus Nephritis; | 1987 |
Ibuprofen and ethanol overdose-induced acute tubular necrosis.
Topics: Acute Kidney Injury; Adolescent; Alcoholic Intoxication; Animals; Cricetinae; Humans; Ibuprofen; Kid | 1987 |
Ibuprofen-associated renal dysfunction. Pathophysiologic mechanisms of acute renal failure, hyperkalemia, tubular necrosis, and proteinuria.
Topics: Acute Kidney Injury; Biomechanical Phenomena; Biopsy; Humans; Hyperkalemia; Ibuprofen; Kidney; Kidne | 1987 |
Over-the-counter ibuprofen and acute renal failure.
Topics: Acute Kidney Injury; Adult; Aspirin; Dehydration; Drug Therapy, Combination; Humans; Ibuprofen; Male | 1986 |
Acute intoxication due to ibuprofen overdose.
Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; I | 1986 |
Ibuprofen toxicosis in a dog.
Topics: Acute Kidney Injury; Animals; Dog Diseases; Dogs; Fluid Therapy; Ibuprofen; Infusions, Parenteral; M | 1986 |
Vasodilator prostaglandins (PG) prevent renal damage after ischemia.
Topics: Acute Kidney Injury; Animals; Dopamine; Ibuprofen; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; | 1987 |
Prostacyclin and thromboxane A2 moderate postischemic renal failure.
Topics: 6-Ketoprostaglandin F1 alpha; Acute Kidney Injury; Animals; Epoprostenol; Ibuprofen; Ischemia; Male; | 1985 |
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperka | 1985 |
Acute oliguric renal failure due to ibuprofen overdose.
Topics: Acute Kidney Injury; Anuria; Female; Humans; Ibuprofen; Middle Aged; Oliguria | 1985 |
Statement on the release of ibuprofen as an over-the-counter medicine. Ad Hoc Committee for the National Kidney Foundation.
Topics: Acute Kidney Injury; Drug Labeling; Humans; Ibuprofen; Nonprescription Drugs; United States | 1985 |