Page last updated: 2024-10-28

ibuprofen and Acute Disease

ibuprofen has been researched along with Acute Disease in 165 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM."9.51The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022)
"Colchicine is effective for the treatment of recurrent pericarditis."9.17A randomized trial of colchicine for acute pericarditis. ( Adler, Y; Belli, R; Beqaraj, F; Brucato, A; Cemin, R; Demarie, D; Ferro, S; Ferrua, S; Forno, D; Imazio, M; Maestroni, S; Maggiolini, S; Spodick, DH; Trinchero, R, 2013)
"Because some febrile patients are unable to swallow or retain oral antipyretic drugs, we carried out a double-blind, placebo-controlled trial in which intravenous ibuprofen (IV-ibuprofen) was given to adults hospitalized with fever associated with acute uncomplicated falciparum malaria treated with oral artesunate plus mefloquine."9.14Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia. ( Duangdee, C; Krudsood, S; Looareesuwan, S; Pothipak, N; Tangpukdee, N; Warrell, DA; Wilairatana, P, 2010)
"Our goal was to determine which of 3 analgesics, acetaminophen, ibuprofen, or codeine, given as a single dose, provides the most efficacious analgesia for children presenting to the emergency department with pain from acute musculoskeletal injuries."9.12A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. ( Clark, E; Correll, R; Gaboury, I; Passi, B; Plint, AC, 2007)
"Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor used to treat pain."9.10A randomized, clinical trial comparing oral celecoxib 200 mg, celecoxib 400 mg, and ibuprofen 600 mg for acute pain. ( Goldberg, J; Kenwood, A; Lavery, R; Salo, DF; Shapiro, T; Varma, V, 2003)
"To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain."9.10Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain. ( Abeln, SB; Beth Goodale, M; Erasala, GN; Hengehold, DA; Hinkle, RT; Nadler, SF; Steiner, DJ; Weingand, KW, 2002)
"5 mg; n = 124) with ibuprofen (200 mg; n = 122) and placebo (n = 126) in patients with moderate-to-severe acute low back pain."9.10Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial. ( Dreiser, RL; Gold, M; Ionescu, E; Liu, JH; Marty, M, 2003)
" In a previous randomized trial we observed that treatment with high-dose acetaminophen (paracetamol) led to a reduction of body temperature in patients with acute ischemic stroke, even when they had no fever."9.10Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]. ( Dippel, DW; Kappelle, LJ; Koudstaal, PJ; Meijer, RJ; van Breda, EJ; van der Worp, HB; van Gemert, HM, 2003)
"The results confirmed that the COX-2-selective inhibitor nimesulide is an effective and well-tolerated agent for use in general practices to treat acute low back pain."9.09Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. ( Autio, L; Jekunen, A; Pohjolainen, T; Vuorela, H, 2000)
"The aim of this study was to assess and compare the efficacy and tolerability of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections (URTIs)."9.09Assessment of the efficacy and safety of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections. ( Cin, S; Köksal, Y; Ulukol, B, 1999)
"Two hundred and nineteen children (boys: 56%, girls: 44%) were included in a randomized, double-blind, multicentre (4 centres) controlled trial designed to assess the efficacy and safety of ibuprofen (IBU) in the treatment of 1 to 6 year-old children with otoscopically proven acute otitis media (AOM), either unilateral or bilateral."9.08A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children. ( Bertin, L; d'Athis, P; Debregeas, B; Duhamel, JF; Guillot, M; Lasfargues, G; Marsac, A; Maudelonde, C; Olive, G; Pons, G, 1996)
" ketorolac is superior to oral ibuprofen in patients presenting to an ED in moderate to severe pain."9.08Intramuscular ketorolac vs oral ibuprofen in emergency department patients with acute pain. ( Neighbor, ML; Puntillo, KA, 1998)
"Our primary objective was to assess the effectiveness of paracetamol (acetaminophen) or NSAIDs, alone or combined, compared with placebo or no treatment in relieving pain in children with AOM."8.93Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children. ( Damoiseaux, RA; Hay, AD; Little, P; Schilder, AG; Sjoukes, A; van de Pol, AC; Venekamp, RP, 2016)
"To review all randomised controlled trials (RCTs) that assess the effects of colchicine alone or combined, compared to any other intervention to prevent further recurrences of pericarditis, in people with acute or recurrent pericarditis."8.90Colchicine for pericarditis. ( Alabed, S; Burls, A; Cabello, JB; Irving, GJ; Qintar, M, 2014)
"We report the case of a 10 year-old girl who had Stevens-Johnson syndrome and cholestasis after ibuprofen therapy."8.82Acute vanishing bile duct syndrome after ibuprofen therapy in a child. ( Bresson-Hadni, S; Felix, S; Jacquemin, E; Menget, A; Taghian, M; Tran, TA, 2004)
" The aim of the study was to explore the mechanism of ibuprofen alleviating myocardial injury caused by acute pancreatitis (AP)."8.12Ibuprofen Alleviates Acute Pancreatitis- (AP-) Induced Myocardial Injury by Inhibiting AIM2. ( Chen, K; Wang, S, 2022)
" Hence, thalidomide (100, 200 and 400 mg/kg) was herein administered to mice to evaluate possible protection against seizures induced by the systemic administration of neurotoxins: 10 mg/kg of 4-aminopyridine (4-AP), 90 mg/kg of pentylenetetrazol (PTZ), or 380 mg/kg of pilocarpine."7.88Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice. ( Campos-Rodriguez, C; Islas-Espinoza, AM; San Juan, ER, 2018)
"Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients."7.75Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009)
"We present a case of a young man with acute pancreatitis probably secondary to an ibuprofen overdose."7.73A case of probable ibuprofen-induced acute pancreatitis. ( Conlon, KC; Magill, P; Neary, P; Ridgway, PF, 2006)
"The efficacy of concurrent treatment of experimental acute otitis media with ibuprofen and ampicillin was evaluated in chinchillas with respect to clearance of the effusion and resolution of mucosal inflammation."7.69Treatment of experimental acute otitis media with ibuprofen and ampicillin. ( Alper, C; Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Jaffe, R, 1995)
"In this study, the efficacy of concurrent treatment of experimental acute otitis media with ibuprofen and ampicillin was evaluated in chinchillas with respect to clearance of the effusion, presence of mucosal inflammation, and modulation of biochemical markers."7.69Effect of ibuprofen treatment during experimental acute otitis media. ( Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Swarts, JD, 1995)
" We have previously shown that ibuprofen, a nonsteroidal anti-inflammatory drug, can improve the hemodynamic alterations of canine endotoxin shock."7.67Effects of ibuprofen on neutrophil function and acute lung injury in canine endotoxin shock. ( Balk, RA; Bone, RC; Jacobs, RF; Townsend, JW; Tryka, AF; Walls, RC, 1988)
" Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis."7.65Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: its prevention by metiamide and cimetidine. ( Mann, NS; Sachdev, AJ, 1977)
"Both rofecoxib and ibuprofen treatment increased the gene expression of the pro-inflammatory mediators, IL6 and CCL2 (chemokine C-C motif ligand 2), following tissue injury compared to the placebo treatment."6.73Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. ( Dionne, RA; Hamza, M; Ramsay, ES; Wahl, SM; Wang, XM; Wu, TX, 2007)
"The information from the single trial in acute postoperative pain suggests it to be a useful analgesic, but at doses not very different from racemic ibuprofen."6.45Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA, 2009)
" It is generally well tolerated after single or multiple doses and short-term use is not expected to produce any of the serious adverse effects typically associated with the long-term use of opioids or NSAIDs."6.43Oxycodone/Ibuprofen combination tablet: a review of its use in the management of acute pain. ( Oldfield, V; Perry, CM, 2005)
"This randomized study suggests that topical 1% lidocaine ear drops with paracetamol or ibuprofen seems to provide effective and rapid relief for children presenting with ear pain attributed to AOM."5.51The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media. ( Alabaz, D; Albayrak, E; Bedir, T; Bozdemir, ŞE; Büyükcam, A; Çelebi, S; Çiftçi, E; İlarslan, EÇ; Kara, A; Kara, M; Kara, SS; Kara, TT; Karakaşlılar, S; Karbuz, A; Kaya, C; Öz, FN; Özdemir, H; Sali, E; Somer, A; Sönmez, G; Sütçü, M; Tezer, H, 2022)
"Acute generalized exanthematic pustulosis (AGEP) is characterized by a generalized rash and sterile disseminated, sometimes coalescing subcorneal pustules."5.35Acute localized exanthematous pustulosis (ALEP) caused by Ibuprofen. A case report. ( Dhawan, V; Modi, M; Rastogi, S, 2009)
"Ibuprofen is a nonsteroidal anti-inflammatory drug used in the treatment of rheumatoid arthritis and osteoarthritis."5.26Ibuprofen in the treatment of acute gouty arthritis. ( Alepa, FP; Nashel, DJ; Schweitz, MC, 1978)
"Colchicine is effective for the treatment of recurrent pericarditis."5.17A randomized trial of colchicine for acute pericarditis. ( Adler, Y; Belli, R; Beqaraj, F; Brucato, A; Cemin, R; Demarie, D; Ferro, S; Ferrua, S; Forno, D; Imazio, M; Maestroni, S; Maggiolini, S; Spodick, DH; Trinchero, R, 2013)
"No significant differences were observed in the number of days with cough between patients with uncomplicated acute bronchitis and discoloured sputum treated with ibuprofen, amoxicillin-clavulanic acid, or placebo."5.17Efficacy of anti-inflammatory or antibiotic treatment in patients with non-complicated acute bronchitis and discoloured sputum: randomised placebo controlled trial. ( Bayona, C; Cots, JM; Llor, C; Miravitlles, M; Moragas, A; Morros, R; Pera, H; Plana-Ripoll, O, 2013)
"Acetaminophen alone may not be as effective in reducing pain-related physiological and behavioral changes as acetaminophen plus codeine or ibuprofen plus midazolam during diagnostic tympanocentesis."5.15Pain management in young children undergoing diagnostic tympanocentesis. ( Chandra, A; Colborn, DK; Hoberman, A; Hooper, EG; Kurs-Lasky, M; Reis, EC; Rockette, HE; Shaikh, N, 2011)
"Because some febrile patients are unable to swallow or retain oral antipyretic drugs, we carried out a double-blind, placebo-controlled trial in which intravenous ibuprofen (IV-ibuprofen) was given to adults hospitalized with fever associated with acute uncomplicated falciparum malaria treated with oral artesunate plus mefloquine."5.14Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia. ( Duangdee, C; Krudsood, S; Looareesuwan, S; Pothipak, N; Tangpukdee, N; Warrell, DA; Wilairatana, P, 2010)
"Our goal was to determine which of 3 analgesics, acetaminophen, ibuprofen, or codeine, given as a single dose, provides the most efficacious analgesia for children presenting to the emergency department with pain from acute musculoskeletal injuries."5.12A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma. ( Clark, E; Correll, R; Gaboury, I; Passi, B; Plint, AC, 2007)
" In a previous randomized trial we observed that treatment with high-dose acetaminophen (paracetamol) led to a reduction of body temperature in patients with acute ischemic stroke, even when they had no fever."5.10Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]. ( Dippel, DW; Kappelle, LJ; Koudstaal, PJ; Meijer, RJ; van Breda, EJ; van der Worp, HB; van Gemert, HM, 2003)
"Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor used to treat pain."5.10A randomized, clinical trial comparing oral celecoxib 200 mg, celecoxib 400 mg, and ibuprofen 600 mg for acute pain. ( Goldberg, J; Kenwood, A; Lavery, R; Salo, DF; Shapiro, T; Varma, V, 2003)
"To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain."5.10Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain. ( Abeln, SB; Beth Goodale, M; Erasala, GN; Hengehold, DA; Hinkle, RT; Nadler, SF; Steiner, DJ; Weingand, KW, 2002)
"5 mg; n = 124) with ibuprofen (200 mg; n = 122) and placebo (n = 126) in patients with moderate-to-severe acute low back pain."5.10Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial. ( Dreiser, RL; Gold, M; Ionescu, E; Liu, JH; Marty, M, 2003)
"The results confirmed that the COX-2-selective inhibitor nimesulide is an effective and well-tolerated agent for use in general practices to treat acute low back pain."5.09Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen. ( Autio, L; Jekunen, A; Pohjolainen, T; Vuorela, H, 2000)
"The aim of this study was to assess and compare the efficacy and tolerability of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections (URTIs)."5.09Assessment of the efficacy and safety of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections. ( Cin, S; Köksal, Y; Ulukol, B, 1999)
"To compare the incidence of serious adverse clinical events among children <2 years old given ibuprofen and acetaminophen to control fever."5.09The safety of acetaminophen and ibuprofen among children younger than two years old. ( Lesko, SM; Mitchell, AA, 1999)
"Two hundred and nineteen children (boys: 56%, girls: 44%) were included in a randomized, double-blind, multicentre (4 centres) controlled trial designed to assess the efficacy and safety of ibuprofen (IBU) in the treatment of 1 to 6 year-old children with otoscopically proven acute otitis media (AOM), either unilateral or bilateral."5.08A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children. ( Bertin, L; d'Athis, P; Debregeas, B; Duhamel, JF; Guillot, M; Lasfargues, G; Marsac, A; Maudelonde, C; Olive, G; Pons, G, 1996)
" ketorolac is superior to oral ibuprofen in patients presenting to an ED in moderate to severe pain."5.08Intramuscular ketorolac vs oral ibuprofen in emergency department patients with acute pain. ( Neighbor, ML; Puntillo, KA, 1998)
"Monotherapy with reaferon (alpha 2-interferon) versus prodigiosan plus ibuprofen combination was investigated in acute viral hepatitis B."5.07[Reaferon and interferonogenes in the therapy of acute viral hepatitis B]. ( Andreĭchin, MA; Rudchik, AS; Zmyzgova, AV, 1991)
"Our primary objective was to assess the effectiveness of paracetamol (acetaminophen) or NSAIDs, alone or combined, compared with placebo or no treatment in relieving pain in children with AOM."4.93Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children. ( Damoiseaux, RA; Hay, AD; Little, P; Schilder, AG; Sjoukes, A; van de Pol, AC; Venekamp, RP, 2016)
"To review all randomised controlled trials (RCTs) that assess the effects of colchicine alone or combined, compared to any other intervention to prevent further recurrences of pericarditis, in people with acute or recurrent pericarditis."4.90Colchicine for pericarditis. ( Alabed, S; Burls, A; Cabello, JB; Irving, GJ; Qintar, M, 2014)
"We report the case of a 10 year-old girl who had Stevens-Johnson syndrome and cholestasis after ibuprofen therapy."4.82Acute vanishing bile duct syndrome after ibuprofen therapy in a child. ( Bresson-Hadni, S; Felix, S; Jacquemin, E; Menget, A; Taghian, M; Tran, TA, 2004)
"Ibuprofen is prescribed for children for the treatment of acute pain and fever, and for juvenile idiopathic arthritis."4.82A general overview of the use of ibuprofen in paediatrics. ( Autret-Leca, E, 2003)
"In parallel with experimental research into methods for salvage of ischemic myocardium after acute myocardial infarction (AMI) over the last decade, there has been a growing interest in prostaglandins (PG) and their inhibition by aspirin-like drugs or nonsteroidal anti-inflammatory drugs (NSAID)."4.76Prostaglandin inhibition and myocardial infarct size. ( Becker, LC; Jugdutt, BI, 1981)
" The aim of the study was to explore the mechanism of ibuprofen alleviating myocardial injury caused by acute pancreatitis (AP)."4.12Ibuprofen Alleviates Acute Pancreatitis- (AP-) Induced Myocardial Injury by Inhibiting AIM2. ( Chen, K; Wang, S, 2022)
" Hence, thalidomide (100, 200 and 400 mg/kg) was herein administered to mice to evaluate possible protection against seizures induced by the systemic administration of neurotoxins: 10 mg/kg of 4-aminopyridine (4-AP), 90 mg/kg of pentylenetetrazol (PTZ), or 380 mg/kg of pilocarpine."3.88Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice. ( Campos-Rodriguez, C; Islas-Espinoza, AM; San Juan, ER, 2018)
"A9 years boy diagnosed with nasopharyngeal carcinoma was started on chemotherapy protocol including 5-fluorouracil."3.81Chemotherapy Induced Acute Pericarditis in a Child. ( Almoukirish, S; Jadoon, S; Khan, MA; Momenah, TS; Rahman, A, 2015)
"Empirical evidence is needed to guide adequate postpartum pain relief of methadone and buprenorphine stabilized patients."3.75Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy. ( Dahne, J; Johnson, R; Jones, HE; Lemoine, L; Milio, L; O'Grady, K; Ordean, A; Selby, P, 2009)
"the management of acute, benign pericarditis was limited nearly exclusively to the prescription of aspirin."3.73[Acute pericarditis: results of a survey of treatment practices of cardiologists]. ( Blanc, JJ; Boschat, J; Cornily, JC; Gilard, M; Le Gal, G; Tram-Lebaillif, TN, 2006)
" In a chronic model, by acetic acid-induced gastric ulcers, COX-2 was expressed at 7 days and was also associated with PGE(2) increase."3.73COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions. ( Alarcón de la Lastra, C; Bruseghini, L; Manuel Herrerias, J; Motilva, V; Sánchez-Fidalgo, S, 2005)
"We present a case of a young man with acute pancreatitis probably secondary to an ibuprofen overdose."3.73A case of probable ibuprofen-induced acute pancreatitis. ( Conlon, KC; Magill, P; Neary, P; Ridgway, PF, 2006)
"The efficacy of concurrent treatment of experimental acute otitis media with ibuprofen and ampicillin was evaluated in chinchillas with respect to clearance of the effusion and resolution of mucosal inflammation."3.69Treatment of experimental acute otitis media with ibuprofen and ampicillin. ( Alper, C; Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Jaffe, R, 1995)
"To compare the clinical efficacy of single doses of intramuscular ketorolac and oral ibuprofen in the emergency department (ED) treatment of acute pain."3.69NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac. ( Price, SD; Watson, WA; Wright, JM, 1994)
"In this study, the efficacy of concurrent treatment of experimental acute otitis media with ibuprofen and ampicillin was evaluated in chinchillas with respect to clearance of the effusion, presence of mucosal inflammation, and modulation of biochemical markers."3.69Effect of ibuprofen treatment during experimental acute otitis media. ( Burckart, GJ; Diven, WF; Doyle, WJ; Evans, RW; Swarts, JD, 1995)
" We report a HIV-infected patient who on two occasions developed acute pulmonary edema related to the administration of ibuprofen."3.68Drug-induced pulmonary edema in a patient infected with human immunodeficiency virus. ( Chetty, KG; Mahutte, CK; Ramirez, MM, 1993)
"(1) hemorrhagic pancreatitis was associated with high levels of PGI2 in blood 15 times and in hemorrhagic ascitic fluid 25 times that of baseline; (2) steroids and ibuprofen blocked PGI2 production (p less than 0."3.67Effect of prostaglandin blockers on ascites fluid in pancreatitis. ( Farias, LR; Frey, CF; Gunther, R; Holcroft, JW, 1985)
" We have previously shown that ibuprofen, a nonsteroidal anti-inflammatory drug, can improve the hemodynamic alterations of canine endotoxin shock."3.67Effects of ibuprofen on neutrophil function and acute lung injury in canine endotoxin shock. ( Balk, RA; Bone, RC; Jacobs, RF; Townsend, JW; Tryka, AF; Walls, RC, 1988)
"To study the role of the vasodilatory, antiaggregatory prostacyclin (PGI2) and its endogenous antagonist thromboxane A2 (TxA2) in acute pancreatitis, we measured serum thromboxane B2 (TxB2, which indicates platelet TxA2 production) and plasma 6-keto-prostaglandin F1 alpha (6-keto-PGF1 alpha, which indicates systemic PGI2 production) from sequential blood samples in trypsin and taurocholate induced acute canine hemorrhagic pancreatitis (AHP)."3.67Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs. ( Jalovaara, P; Kairaluoma, M; Kiviniemi, H; Laitinen, S; Rämö, J; Ståhlberg, M; Viinikka, L, 1987)
"The effects of sulindac were compared with those of ibuprofen or naproxen on creatinine clearance and urinary prostanoids in patients with severe alcoholic cirrhosis."3.67Reversible acute decrease in renal function by NSAIDs in cirrhosis. ( Anderson, SA; Brater, DC; Brown-Cartwright, D, 1987)
"Three young women with systemic lupus erythematosus who were given ibuprofen for arthritis voluntarily discontinued taking the drug."3.66Acute adverse reactions to ibuprofen in systemic lupus erythematosus. ( Finch, WR; Strottman, MP, 1979)
" Metiamide and cimetidine were effective in preventing this type of experimental acute erosive gastritis."3.65Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: its prevention by metiamide and cimetidine. ( Mann, NS; Sachdev, AJ, 1977)
"Individuals with episodic migraine were screened at the Jefferson Headache Center."3.01Intravenous ibuprofen for acute treatment of migraine: A double-blind, randomized, placebo-controlled pilot study. ( Curran, JG; Hopkins, MM; Keith, SW; Silberstein, SD; Yuan, H, 2021)
"Acute bronchitis is one of the most prevalent respiratory infections in primary care, and in more than 90% of the cases antibiotics are prescribed, mainly when purulent expectoration is present."2.76Effectiveness of anti-inflammatory treatment versus antibiotic therapy and placebo for patients with non-complicated acute bronchitis with purulent sputum. The BAAP Study protocol. ( Bayona, C; Boada, A; Cots, JM; Fernández, Y; Llor, C; Miravitlles, M; Moragas, A; Morros, R; Pera, H, 2011)
"Acute back and neck strains are very common."2.75Heat or cold packs for neck and back strain: a randomized controlled trial of efficacy. ( Garra, G; Gupta, N; Leno, R; Mathaikutty, B; Singer, AJ; Taira, BR; Thode, HJ, 2010)
"Both rofecoxib and ibuprofen treatment increased the gene expression of the pro-inflammatory mediators, IL6 and CCL2 (chemokine C-C motif ligand 2), following tissue injury compared to the placebo treatment."2.73Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. ( Dionne, RA; Hamza, M; Ramsay, ES; Wahl, SM; Wang, XM; Wu, TX, 2007)
"Rizatriptan was superior to ibuprofen and placebo in relieving headache at 2 h but not at 24 h."2.73Rizatriptan vs. ibuprofen in migraine: a randomised placebo-controlled trial. ( Kalita, J; Misra, UK; Yadav, RK, 2007)
"Ibuprofen was included as a reference nonselective NSAID."2.72Rofecoxib in the acute treatment of migraine: a randomized controlled clinical trial. ( Barraclough, E; Dahlof, C; Klipfel, M; Lines, C; Loeys, T; Malbecq, W; Reines, S; Saper, J; So, Y; Tfelt-Hansen, P; Visser, H; Yuen, E, 2006)
"Both ibuprofen and rofecoxib were superior to placebo in aborting an acute migraine attack, and there was no significant difference in their efficacy in an acute migraine attack."2.71Rofecoxib versus ibuprofen for acute treatment of migraine: a randomised placebo controlled trial. ( Jose, M; Kalita, J; Misra, UK, 2004)
"Forty migraine patients participated in this multicenter, double-blind, crossover, randomized, placebo-controlled trial."2.69Effectiveness of ibuprofen-arginine in the treatment of acute migraine attacks. ( Franchini, S; Granella, F; Lanfranchi, S; Manzoni, GC; Nappi, G; Sandrini, G, 1998)
"Ibuprofen was significantly better than all other treatments for all measures of analgesic activity."2.67Clinical evaluation of H1-receptor and H2-receptor antagonists for acute postoperative pain. ( Berthold, CW; Dionne, RA, 1993)
"Acute mountain sickness is a common condition occurring in healthy subjects that undergo rapid ascent without prior acclimatization, as low as 2500 meters above sea level."2.66Ibuprofen versus acetazolamide for prevention of acute mountain sickness. ( Irarrázaval, S; Schilling, M, 2020)
" Ibuprofen is associated with certain well-known gastrointestinal adverse effects that are related to dose and patient population."2.66Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review. ( Dowling, P; Paladini, A; Pergolizzi, JV; Varrassi, G, 2020)
"Ibuprofen 400 mg was more effective than acetaminophen 1000 mg for Sum Pain Intensity Difference (SPID), Total Pain Relief (TOTPAR), sum pain half-gone, and overall evaluation (P less than ."2.66Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study. ( Cohn, P; Cooper, SA; Gelb, S; Goldman, E; Schachtel, BP, 1989)
"The information from the single trial in acute postoperative pain suggests it to be a useful analgesic, but at doses not very different from racemic ibuprofen."2.45Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA, 2009)
"This case was diagnosed as eosinophilic pneumonia caused by several drugs, and to our knowledge, this is the first report in Japan of ibuprofen (EVE-A tablet)-induced pneumonia."2.45[Acute eosinophilic pneumonia caused by several drugs including ibuprofen]. ( Anan, E; Hiramatsu, K; Hirata, N; Ishii, H; Kadota, J; Kai, N; Kishi, K; Nakama, K; Shirai, R; Tokimatsu, I, 2009)
"The MeSH search terms used were migraine disorders, headache, vascular headache, ibuprofen, adult, and clinical trial."2.44Efficacy of low-dose ibuprofen in acute migraine treatment: systematic review and meta-analysis. ( Kittikulsuth, W; Poolsup, N; Pudchakan, P; Suthisisang, C; Wiwatpanich, P, 2007)
"Acute pericarditis is often accompanied by some degree of myocarditis."2.44Myopericarditis: Etiology, management, and prognosis. ( Imazio, M; Trinchero, R, 2008)
" It is generally well tolerated after single or multiple doses and short-term use is not expected to produce any of the serious adverse effects typically associated with the long-term use of opioids or NSAIDs."2.43Oxycodone/Ibuprofen combination tablet: a review of its use in the management of acute pain. ( Oldfield, V; Perry, CM, 2005)
"In the acute migraine attack, a single dose of either ibuprofen 10 mg/kg or paracetamol 15 mg/kg has been shown to be effective, with only a few adverse effects."2.43[Pharmacologic treatment of acute migraine attack in children]. ( Auvin, S; Cuvellier, JC; Joriot, S; Vallée, L, 2005)
"The biochemical findings suggest renal tubular acidosis, type 2, most likely caused by the excess intake of ibuprofen, a drug which can cause renal dysfunctions with life-threatening electrolyte abnormalities."2.40[Renal tubular acidosis with severe hypokalemic tetraparesis after ibuprofen intake]. ( Druschky, A; Erbguth, F; Gaul, C; Heckmann, JG; Neundörfer, B; Schöcklmann, H, 1999)
"Ibuprofen is a potent cyclooxygenase inhibitor known to reduce the production of arachidonic acid metabolites."2.38Ibuprofen in acute-care therapy. ( Ehrlich, HP; Rockwell, WB, 1990)
"Acute pericarditis has a wide spectrum of clinical presentations largely depending on underlying aetiologies."1.62Age- and sex-based differences in patients with acute pericarditis. ( Antonopoulos, AS; Lazaros, G; Lazarou, E; Tousoulis, D; Vassilopoulos, D; Vlachopoulos, C; Vogiatzi, G, 2021)
"The consequences of chronic insufficient sleep for health remain uncertain."1.46Decreased alertness due to sleep loss increases pain sensitivity in mice. ( Alexandre, C; Ferreira, A; Latremoliere, A; Miracca, G; Scammell, TE; Woolf, CJ; Yamamoto, M, 2017)
"A viral swab was positive for influenza B."1.43An Interesting Case of Viral Pericarditis. ( de Almeida, CL; Kam, AJ; van Diepen, KM, 2016)
"Treatment with ibuprofen and splinting resulted in complete symptom resolution."1.39Acute calcific tendinitis of the wrist. ( Bral, D; Geiderman, JM; Torbati, SS, 2013)
"Acute generalized exanthematic pustulosis (AGEP) is characterized by a generalized rash and sterile disseminated, sometimes coalescing subcorneal pustules."1.35Acute localized exanthematous pustulosis (ALEP) caused by Ibuprofen. A case report. ( Dhawan, V; Modi, M; Rastogi, S, 2009)
"We report the case of hypoxic interstitial pneumonitis with eosinophilic alveolitis induced by ibuprofen."1.34[Diffuse interstitial pneumonitis with acute respiratory failure]. ( Daoud, K; François, T; Gounant, V; Milleron, B; Prigent, H, 2007)
"We assessed the quality of assessment and reporting of adverse effects in randomized, double-blind clinical trials of single-dose acetaminophen or ibuprofen compared with placebo in moderate to severe postoperative pain."1.30Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain. ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA, 1999)
"6 hour-1, corresponding to a half-life of drug in the effect compartment of 1."1.28Effect of age on ibuprofen pharmacokinetics and antipyretic response. ( Kauffman, RE; Nelson, MV, 1992)
"Flurbiprofen was given at 0."1.26Effects of flurbiprofen on myocardial cell damage in acute myocardial ischemia. ( Carrow, BA; Lefer, AM; Smith, EF, 1980)
"Ibuprofen was administered intravenously at a dose of 12."1.26Beneficial effects of ibuprofen in acute myocardial ischemia. ( Lefer, AM; Polansky, EW, 1979)
"Ibuprofen is a nonsteroidal anti-inflammatory drug used in the treatment of rheumatoid arthritis and osteoarthritis."1.26Ibuprofen in the treatment of acute gouty arthritis. ( Alepa, FP; Nashel, DJ; Schweitz, MC, 1978)

Research

Studies (165)

TimeframeStudies, this research(%)All Research%
pre-199029 (17.58)18.7374
1990's35 (21.21)18.2507
2000's59 (35.76)29.6817
2010's33 (20.00)24.3611
2020's9 (5.45)2.80

Authors

AuthorsStudies
Amir, M1
Kumar, H1
Javed, SA1
Akhter, M1
Husain, A1
Azad, B1
Ajmal, M1
Yuan, H1
Curran, JG1
Keith, SW1
Hopkins, MM1
Silberstein, SD1
Kara, A1
Büyükcam, A1
Sütçü, M1
Sali, E1
Bozdemir, ŞE1
Kara, M1
İlarslan, EÇ1
Kaya, C1
Karakaşlılar, S1
Sönmez, G1
Kara, SS1
Bedir, T1
Albayrak, E1
Kara, TT1
Çelebi, S1
Öz, FN1
Karbuz, A1
Somer, A1
Alabaz, D1
Tezer, H1
Özdemir, H1
Çiftçi, E1
Chen, K1
Wang, S1
Nicollas, R1
Moreddu, E1
Le Treut-Gay, C1
Mancini, J1
Akkari, M1
Mondain, M1
Scavarda, D1
Hosanna, G1
Fayoux, P1
Pondaven-Letourmy, S1
Lescanne, E1
Triglia, JM1
Varrassi, G1
Pergolizzi, JV1
Dowling, P1
Paladini, A1
Moore, N1
Carleton, B1
Blin, P1
Bosco-Levy, P1
Droz, C1
Schilling, M1
Irarrázaval, S1
Lazaros, G1
Antonopoulos, AS1
Lazarou, E1
Vlachopoulos, C1
Vogiatzi, G1
Vassilopoulos, D1
Tousoulis, D1
Contorno, S1
Cozzi, G1
Berti, I1
Barbi, E1
Taddio, A1
Alexandre, C1
Latremoliere, A1
Ferreira, A1
Miracca, G1
Yamamoto, M1
Scammell, TE1
Woolf, CJ1
Jeric, M1
Surjan, N1
Jelicic Kadic, A1
Riva, N1
Puljak, L1
Sridharan, K1
Sivaramakrishnan, G1
Steurer, J1
Bickler, P1
Feiner, JR1
Lundeberg, J1
Islas-Espinoza, AM1
Campos-Rodriguez, C1
San Juan, ER1
Moore, M1
Trill, J1
Simpson, C1
Webley, F1
Radford, M1
Stanton, L1
Maishman, T1
Galanopoulou, A1
Flower, A1
Eyles, C1
Willcox, M1
Hay, AD2
van der Werf, E1
Gibbons, S1
Lewith, G1
Little, P2
Griffiths, G1
Lilly, LS1
Imazio, M3
Brucato, A2
Barbieri, A1
Ferroni, F1
Maestroni, S2
Ligabue, G1
Chinaglia, A1
Cumetti, D1
Della Casa, G1
Bonomi, F1
Mantovani, F1
Di Corato, P1
Lugli, R1
Faletti, R1
Leuzzi, S1
Bonamini, R1
Modena, MG1
Belli, R2
Cemin, R1
Ferrua, S1
Maggiolini, S1
Beqaraj, F1
Demarie, D1
Forno, D1
Ferro, S1
Trinchero, R2
Spodick, DH1
Adler, Y1
Llor, C2
Moragas, A2
Bayona, C2
Morros, R2
Pera, H2
Plana-Ripoll, O1
Cots, JM2
Miravitlles, M2
Lopez, JI1
Holdridge, A1
Mendizabal, JE1
Fiorelli, EM1
Ferrari, L1
Alabed, S1
Cabello, JB1
Irving, GJ1
Qintar, M1
Burls, A1
van Diepen, KM1
de Almeida, CL1
Kam, AJ1
Kanaan, NC1
Lipman, GS1
Constance, BB1
Holck, PS1
Preuss, JF1
Williams, SR1
Khan, MA1
Rahman, A1
Almoukirish, S1
Jadoon, S1
Momenah, TS1
Martínez López, AB1
Álvarez Blanco, O1
Luque de Pablos, A1
Morales San-José, MD1
Rodríguez Sanchez de la Blanca, A1
Schmidt, JJ1
Ramazan, L1
Bockemeyer, C1
Günter, HH1
Martens-Lobenhoffer, J1
Ganzenmüller, T1
Bode-Böger, SM1
Kielstein, JT1
Sjoukes, A1
Venekamp, RP1
van de Pol, AC1
Schilder, AG1
Damoiseaux, RA1
Schwartz, JH1
Sclafani, SJ1
Glass, TA1
Sewell, PE1
Rastogi, S1
Modi, M1
Dhawan, V1
Den Hertog, HM1
van der Worp, HB2
Tseng, MC1
Dippel, DW2
Pearce, PZ1
Jones, HE1
O'Grady, K1
Dahne, J1
Johnson, R1
Lemoine, L1
Milio, L1
Ordean, A1
Selby, P1
Anan, E1
Shirai, R1
Kai, N1
Ishii, H1
Hirata, N1
Kishi, K1
Tokimatsu, I1
Nakama, K1
Hiramatsu, K1
Kadota, J1
Moore, RA4
Derry, S1
McQuay, HJ4
Miner, JR1
Sethi, NK1
Shepherd, M1
Aickin, R1
Garra, G1
Singer, AJ1
Leno, R1
Taira, BR1
Gupta, N1
Mathaikutty, B1
Thode, HJ1
Krudsood, S1
Tangpukdee, N1
Wilairatana, P1
Pothipak, N1
Duangdee, C1
Warrell, DA1
Looareesuwan, S1
Mehlisch, DR1
Aspley, S1
Daniels, SE1
Bandy, DP1
Shaikh, N1
Hoberman, A1
Kurs-Lasky, M1
Rockette, HE1
Chandra, A1
Colborn, DK1
Hooper, EG1
Reis, EC1
Pavlidis, AN1
Giannakopoulos, AK1
Danias, PG1
Manolis, AJ1
Popescu, C1
Arama, V1
Gliga, S1
Raval, JP1
Gandhi, AN1
Akhaja, TN1
Myangar, KN1
Patel, NH1
Fernández, Y1
Boada, A1
Worrall, G1
Tahir, T1
Manrique Franco, K1
Aragón Valera, C1
Gutiérrez Medina, S1
Sánchez-Vilar Burdiel, O1
Rovira Loscos, A1
Torbati, SS1
Bral, D1
Geiderman, JM1
Gola, S1
Keshri, GK1
Gupta, A1
Dolezal, T1
Krsiak, M1
Andrade, RJ1
Lucena, MI1
García-Cortés, M1
García-Ruiz, E1
Fernández-Bonilla, E1
Vázquez, L1
Katz, N1
Zemishlany, Z1
Weizman, A1
Dodd, MD1
Graham, CA1
O'Neill, P4
Lewis, DW1
Kellstein, D1
Dahl, G1
Burke, B1
Frank, LM1
Toor, S1
Northam, RS1
White, LW1
Lawson, L1
Salo, DF1
Lavery, R1
Varma, V1
Goldberg, J1
Shapiro, T1
Kenwood, A1
Gopikrishna, V1
Parameswaran, A1
Nadler, SF2
Steiner, DJ2
Petty, SR1
Erasala, GN2
Hengehold, DA2
Weingand, KW2
van Breda, EJ1
van Gemert, HM1
Meijer, RJ1
Kappelle, LJ1
Koudstaal, PJ1
Autret-Leca, E1
Dionne, R1
Shostak, NA1
Riabkova, AA1
Savel'ev, VS1
Maliarova, LP1
Dreiser, RL1
Marty, M1
Ionescu, E1
Gold, M1
Liu, JH1
Gineyts, E1
Mo, JA1
Ko, A1
Henriksen, DB1
Curtis, SP1
Gertz, BJ1
Garnero, P1
Delmas, PD1
Taghian, M1
Tran, TA1
Bresson-Hadni, S1
Menget, A1
Felix, S1
Jacquemin, E1
Morillo, LE1
Misra, UK2
Jose, M1
Kalita, J2
Motilva, V1
Alarcón de la Lastra, C1
Bruseghini, L1
Manuel Herrerias, J1
Sánchez-Fidalgo, S1
Cuvellier, JC1
Joriot, S1
Auvin, S1
Vallée, L1
Blohm, ME1
Schroten, H1
Heusch, A1
Christaras, A1
Micek, M1
Wintgens, J1
Mayatepek, E1
Hoehn, T1
Edwards, JE3
Roberts, T2
Oldfield, V1
Perry, CM1
Kofidis, T1
Lebl, DR1
Swijnenburg, RJ1
Greeve, JM1
Klima, U1
Gold, J1
Xu, C1
Robbins, RC1
Cornily, JC1
Le Gal, G1
Tram-Lebaillif, TN1
Gilard, M1
Boschat, J1
Blanc, JJ1
Guindon, J1
De Léan, A1
Beaulieu, P1
Saper, J1
Dahlof, C1
So, Y1
Tfelt-Hansen, P1
Malbecq, W1
Loeys, T1
Barraclough, E1
Klipfel, M1
Lines, C1
Visser, H1
Reines, S1
Yuen, E1
Vas, J1
Perea-Milla, E1
Mendez, C1
Silva, LC1
Herrera Galante, A1
Aranda Regules, JM1
Martinez Barquin, DM1
Aguilar, I1
Faus, V1
Magill, P1
Ridgway, PF1
Conlon, KC1
Neary, P1
Bradley Stevenson, C1
Wang, XM1
Wu, TX1
Hamza, M1
Ramsay, ES1
Wahl, SM1
Dionne, RA2
Clark, E1
Plint, AC1
Correll, R1
Gaboury, I1
Passi, B1
Delporte, C1
Backhouse, N1
Inostroza, V1
Aguirre, MC1
Peredo, N1
Silva, X1
Negrete, R1
Miranda, HF1
Yadav, RK1
Blanco-Rivera, C1
Campos-García, S1
Daoud, K1
Gounant, V1
Prigent, H1
François, T1
Milleron, B1
Dubbel, G1
Zernikow, B1
Suthisisang, C1
Poolsup, N1
Kittikulsuth, W1
Pudchakan, P1
Wiwatpanich, P1
Dixit, MP1
Nguyen, C1
Carson, T1
Guedes, B1
Dixit, NM1
Bell, JM1
Wang, Y1
Katsu, M2
Adachi, M1
Hayakawa, M2
Fujimori, I2
Kohno, M2
Takeda, Y2
Sekita, K2
Ogihara, K2
Noguchi, T2
Iizuka, K2
Kopolovic, R1
Thrailkill, KM1
Martin, DT1
Ambrose, T1
Vento, M1
Carey, LC1
Cloutier, CT1
Kawai, M1
Yamazaki, S1
Nakagawa, H1
Itoh, S1
Shimada, S1
Ohsuga, H1
Enomoto, S1
Matsuki, Y1
Seki, K1
Yamazaki, F1
Higashi, F1
Sasaki, S1
Court, H1
Streete, P1
Volans, GN1
Jugdutt, BI1
Becker, LC1
Sasaki, GH1
Pang, CY1
Smith, EF1
Carrow, BA1
Lefer, AM2
Diven, WF2
Evans, RW2
Swarts, JD1
Burckart, GJ2
Doyle, WJ2
Alper, C1
Jaffe, R1
Kimoto, N1
Fujimura, A1
Yoshizawa, S1
Yoshida, K1
Murata, T1
Arakawa, K1
Kogawara, S1
Naito, S1
Wright, JM1
Price, SD1
Watson, WA1
Berthold, CW1
Teixeira, MM1
Williams, TJ1
Hellewell, PG1
Chetty, KG1
Ramirez, MM1
Mahutte, CK1
Burhop, KE1
Johnson, RJ1
Simpson, J1
Chenoweth, DE1
Borgia, J1
Fouad, AF1
Rivera, EM1
Walton, RE1
Bertin, L1
Pons, G1
d'Athis, P1
Duhamel, JF1
Maudelonde, C1
Lasfargues, G1
Guillot, M1
Marsac, A1
Debregeas, B1
Olive, G1
Sharma, NK1
Kindelan, JD1
Hutchinson, D1
Lancaster, L1
Barkhof, F1
van Waesberghe, JH1
Uitdehaag, BM1
Polman, CH1
Stoves, J1
Rosenberg, K1
Harnden, P1
Turney, JH1
Neighbor, ML1
Puntillo, KA1
Hargreaves, KM1
Príborský, J1
Takayama, K1
Nagai, T1
Srivastava, M1
Perez-Atayde, A1
Jonas, MM1
Sandrini, G1
Franchini, S1
Lanfranchi, S1
Granella, F1
Manzoni, GC1
Nappi, G1
Gaul, C1
Heckmann, JG1
Druschky, A1
Schöcklmann, H1
Neundörfer, B1
Erbguth, F1
Bailey, SR1
Elliott, J1
Lesko, SM1
Mitchell, AA1
Kaufman, DW1
Kelly, JP1
Wiholm, BE1
Laszlo, A1
Sheehan, JE1
Koff, RS1
Shapiro, S1
Ulukol, B1
Köksal, Y1
Cin, S1
Collins, SL1
Pohjolainen, T1
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Autio, L1
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Glasziou, P1
Menke, ER1
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Heinzelmann, DI1
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Strottman, MP1
Polansky, EW1
Schweitz, MC1
Nashel, DJ1
Alepa, FP1
Carey, PD3
Jenkins, JK2
Byrne, K3
Walsh, CJ1
Fowler, AA3
Sugerman, HJ3
Kauffman, RE1
Nelson, MV1
Skriabin, ON1
Baranchuk, VN1
Manyshev, VG1
Kurygin, AA1
Ragni, MV1
Miller, BJ1
Whalen, R1
Ptachcinski, R1
Kloster, R1
Nestvold, K1
Vilming, ST1
Leeper-Woodford, SK1
Fisher, BJ1
Blocher, C1
Sielaff, TD1
Blocher, CR1
Cooper, KR1
Andreĭchin, MA4
Zmyzgova, AV1
Rudchik, AS4
Agus, B1
Nelson, J1
Kramer, N1
Mahal, SS1
Rosenstein, ED1
Kaufman, LD1
Rockwell, WB1
Ehrlich, HP1
Sloan, JP1
Hain, R1
Pownall, R1
Jemec, GB1
Rasmussen, I1
Borak, VF2
Cooper, SA1
Schachtel, BP1
Goldman, E1
Gelb, S1
Cohn, P1
Ayres, JG1
Fleming, DM1
Whittington, RM1
Balk, RA1
Jacobs, RF1
Tryka, AF1
Townsend, JW1
Walls, RC1
Bone, RC1
Kiviniemi, H1
Rämö, J1
Ståhlberg, M1
Laitinen, S1
Jalovaara, P1
Viinikka, L1
Kairaluoma, M1
Mashkovskiĭ, MD1
Bobkov, IuG1
Shvarts, GIa1
Ivanova, IA1
Brater, DC1
Anderson, SA1
Brown-Cartwright, D1
Primos, W1
Bhatnager, A1
Bishop, P1
Evans, OB1
Schneider, PD1
Eliasen, K1
Jensen, NH1
Andersen, JB1
Hasselstrøm, L1
Godtfredsen, J1
Hulton, NR1
Johnson, DJ1
Wilmore, DW1
Farias, LR1
Frey, CF1
Holcroft, JW1
Gunther, R1
Reeves, WB1
Foley, RJ1
Weinman, EJ1

Clinical Trials (16)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Double-blind, Placebo-controlled Pilot Study to Collect and Evaluate Data on the Use of Intravenous Ibuprofen in the Treatment of an Acute Migraine Attack[NCT01230411]Phase 444 participants (Actual)Interventional2011-06-30Completed
An Open-label, Randomized, 3-way Crossover Study to Evaluate the Pharmacokinetics of Investigational Product Ibuprofen Modified-Release Tablets 800 mg Compared to Ibuprofen Tablets 800 mg in Healthy Volunteers[NCT05329454]Phase 130 participants (Actual)Interventional2020-12-24Completed
Treatment and Prevention of Pericarditis With Colchicine. A Multicenter Double Blind Randomized Trial. The ICAP Trial: Investigation on Colchicine for Acute Pericarditis[NCT00128453]Phase 3240 participants (Actual)Interventional2005-08-31Completed
Outcomes of Low-dose Colchicine in Patients With Myocardial Infarction: A Randomized Controlled Trial[NCT04218786]Phase 20 participants (Actual)Interventional2025-12-31Withdrawn (stopped due to Due to the pandemic, there were logistical issues in continuing the study.)
Colchicine Versus Placebo in Acute Myocarditis Patients to Reduce Late Gadolinium Enhancement Mass on Cardiac Magnetic Resonance and the Risk of Clinical Outcomes: The ARGO Trial[NCT05855746]Phase 3300 participants (Anticipated)Interventional2024-01-22Not yet recruiting
Effect of Low Dose of Colchicine on Platelet Reactivty in Patients With Chronic Coronary Disease[NCT05956145]Phase 380 participants (Anticipated)Interventional2021-06-17Recruiting
Assessment of the Analgesic Efficacy of Intravenous Ibuprofen in Biliary Colic[NCT02268955]22 participants (Actual)Interventional2014-09-09Completed
Addressing Opioid Use Disorder With an External Multimodal Neuromodulation Device: Clinical Evaluation of DuoTherm for Opioid-Sparing in Acute Low Back Pain[NCT04491175]60 participants (Anticipated)Interventional2022-06-23Recruiting
Phase III Clinical Trial Studying Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children[NCT02477007]Phase 3304 participants (Actual)Interventional2015-12-03Completed
A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy[NCT01267136]Phase 484 participants (Actual)Interventional2011-01-31Completed
Ibuprofen vs. Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?[NCT01605240]50 participants (Anticipated)Interventional2012-07-31Recruiting
Clinical, Microbiological and Quality of Life Outcomes Following Use of Systemic and Local Antimicrobials in the Management of Odontogenic Infections in Paediatric Patients[NCT03761264]Phase 255 participants (Actual)Interventional2018-09-18Completed
Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial[NCT03007342]78 participants (Anticipated)Interventional2017-01-31Not yet recruiting
The Randomized Double-Blind Comparison of Analgesic Efficacy Between Intravenous Forms of Ibuprofen 400 and Ibuprofen 800 mg in Acute Mechanical Low Back Pain in the Emergency Department[NCT06064175]Phase 4144 participants (Actual)Interventional2022-01-01Completed
The Incidence of Postoperative Pain After Using Different Types of Sealers (A Randomized Clinical Trial)[NCT05841290]40 participants (Anticipated)Interventional2023-05-31Not yet recruiting
Study of Bleeding Tendency, Platelet Function, and Pharmacokinetics of Azidothymidine (AZT) and Motrin (Ibuprofen) in HIV-Infected Hemophiliacs[NCT00002276]0 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Comparison of Proportion of Subjects in Control and Active Treatment Groups Who Have Pain Relief at 2 Hours After the Completion of the Double-blind Treatment Infusion.

Comparison of proportion of subjects in each treatment group (active treatment and placebo) who have pain relief at 2 hours after the completion of the double-blind treatment infusion. Pain relief is defined as a reduction in headache pain level from severe or moderate decreased to mild or headache-free, respectively. (NCT01230411)
Timeframe: 2 hours

InterventionParticipants (Count of Participants)
Placebo10
Ibuprofen17

Pain Score 120 Minutes After Study Medication Administration

Pain is measured on a visual analog scale 0=no pain and 10=worst pain imaginable. (NCT02268955)
Timeframe: 120 minutes post medication administration

Interventionscore on a scale (Median)
Control Group: Adults Age 18-55 Years3.0
IV Ibuprofen: Adults Age 18-55 Years0.3

Efficacy of Two Different Liquid Pain Medications: Tramadol vs. Codeine/Acetaminophen During the Post-tonsillectomy Recovery Period.

Average number of post-operative days with pain score >4/10. Pain score assessments were administered once daily by parents using either the Numeric Rating Scale (NRS-11) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 8-15 (von Baeyer et al., 2009) or the Faces Pain Scale-Revised (FPS-R) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 4-10 (Hicks et al., 2001). (NCT01267136)
Timeframe: Efficacy was assessed daily during the 10-day postoperative recovery period.

Interventiondays (Median)
Capital® With Codeine Suspension1.5
Tramadol Suspension1

Number of Participants Reporting Side Effects During the Post-tonsillectomy Recovery Period.

Parent-reported side effects entered in 10-day diary. (NCT01267136)
Timeframe: Side effects will be observed and recorded daily by caregivers for a total of 10 days in the take-home diary.

,
Interventionparticipants (Number)
NauseaVomitingFeverItchingRashSweatingDizzinessHeadacheConstipationOversedationTonsil bleed
Capital® With Codeine Suspension202111519151221143
Tramadol Suspension201810121717172180

Reviews

29 reviews available for ibuprofen and Acute Disease

ArticleYear
Ibuprofen Safety at the Golden Anniversary: Are all NSAIDs the Same? A Narrative Review.
    Advances in therapy, 2020, Volume: 37, Issue:1

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Dose-Response R

2020
Ibuprofen versus acetazolamide for prevention of acute mountain sickness.
    Medwave, 2020, Jun-11, Volume: 20, Issue:5

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Anti-Inflammatory Agents, Non-Steroidal; Carbonic A

2020
Treatment of acute migraine attacks in children with analgesics on the World Health Organization Essential Medicines List: A systematic review and GRADE evidence synthesis.
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:9

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Migraine Disorders

2018
Treatment of acute and recurrent idiopathic pericarditis.
    Circulation, 2013, Apr-23, Volume: 127, Issue:16

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; C-Reactive Protein; Colchicine; Dis

2013
Altitude headache.
    Current pain and headache reports, 2013, Volume: 17, Issue:12

    Topics: Acute Disease; Adaptation, Physiological; Altitude; Altitude Sickness; Anti-Inflammatory Agents; Asp

2013
Colchicine for pericarditis.
    The Cochrane database of systematic reviews, 2014, Aug-28, Issue:8

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colchicine; Humans; Ibuprofen; Indo

2014
Paracetamol (acetaminophen) or non-steroidal anti-inflammatory drugs, alone or combined, for pain relief in acute otitis media in children.
    The Cochrane database of systematic reviews, 2016, 12-15, Volume: 12

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Age

2016
Cooling therapy for acute stroke.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Acetaminophen; Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Humans; Hypothermia

2009
[Acute eosinophilic pneumonia caused by several drugs including ibuprofen].
    Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society, 2009, Volume: 47, Issue:5

    Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Cephalosporins; Humans; Ibuprofen; Ly

2009
Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults.
    The Cochrane database of systematic reviews, 2009, Jul-08, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-

2009
Acute otitis media.
    Clinical evidence, 2002, Issue:7

    Topics: Acetaminophen; Acute Disease; Anti-Bacterial Agents; Chewing Gum; Child, Preschool; Female; Humans;

2002
Acute otitis media.
    Clinical evidence, 2002, Issue:8

    Topics: Acetaminophen; Acute Disease; Anti-Bacterial Agents; Chewing Gum; Child, Preschool; Female; Humans;

2002
A general overview of the use of ibuprofen in paediatrics.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Chil

2003
Relative efficacy of selective COX-2 inhibitors compared with over-the-counter ibuprofen.
    International journal of clinical practice. Supplement, 2003, Issue:135

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Ibuprofen

2003
Acute vanishing bile duct syndrome after ibuprofen therapy in a child.
    The Journal of pediatrics, 2004, Volume: 145, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Bile Duct Diseases; Bile Ducts, Intrahepatic

2004
Migraine headache.
    Clinical evidence, 2003, Issue:10

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Dicl

2003
[Pharmacologic treatment of acute migraine attack in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2005, Volume: 12, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Intranasal; Administration, Oral; Adolescent; Age Fact

2005
Acute pain: individual patient meta-analysis shows the impact of different ways of analysing and presenting results.
    Pain, 2005, Volume: 116, Issue:3

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Ibuprofen; Lact

2005
Acute otitis media in children.
    Clinical evidence, 2005, Issue:13

    Topics: Acetaminophen; Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child;

2005
Oxycodone/Ibuprofen combination tablet: a review of its use in the management of acute pain.
    Drugs, 2005, Volume: 65, Issue:16

    Topics: Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Area Under Curve; Clinical Trials as To

2005
Otitis media in children (acute).
    Clinical evidence, 2006, Issue:15

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anti-Inflammatory Age

2006
Efficacy of low-dose ibuprofen in acute migraine treatment: systematic review and meta-analysis.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:11

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double-Bli

2007
Myopericarditis: Etiology, management, and prognosis.
    International journal of cardiology, 2008, Jun-23, Volume: 127, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Echocardiography; Electrocardiography; Human

2008
Prostaglandin inhibition and myocardial infarct size.
    Clinical cardiology, 1981, Volume: 4, Issue:3

    Topics: Acute Disease; Animals; Aspirin; Coronary Disease; Humans; Ibuprofen; Indomethacin; Models, Biologic

1981
[Renal tubular acidosis with severe hypokalemic tetraparesis after ibuprofen intake].
    Deutsche medizinische Wochenschrift (1946), 1999, Apr-23, Volume: 124, Issue:16

    Topics: Acidosis, Renal Tubular; Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Di

1999
Single dose dihydrocodeine for acute postoperative pain.
    The Cochrane database of systematic reviews, 2000, Issue:4

    Topics: Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Humans; Ibuprofen; Pain, Posto

2000
How effective are treatments other than antibiotics for acute sore throat?
    The British journal of general practice : the journal of the Royal College of General Practitioners, 2000, Volume: 50, Issue:459

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic;

2000
Ibuprofen in acute-care therapy.
    Annals of surgery, 1990, Volume: 211, Issue:1

    Topics: Acute Disease; Animals; Cardiomyopathies; Humans; Ibuprofen; Immunity; Lung; Shock; Shock, Septic; W

1990
Bone lesions of acne fulminans. Case report and review of the literature.
    Journal of the American Academy of Dermatology, 1989, Volume: 20, Issue:2 Pt 2

    Topics: Acne Vulgaris; Acute Disease; Adolescent; Betamethasone; Biopsy; Clavicle; Drug Administration Sched

1989

Trials

44 trials available for ibuprofen and Acute Disease

ArticleYear
Intravenous ibuprofen for acute treatment of migraine: A double-blind, randomized, placebo-controlled pilot study.
    Headache, 2021, Volume: 61, Issue:9

    Topics: Acute Disease; Administration, Intravenous; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-B

2021
The effectiveness of topical 1% lidocaine with systemic oral analgesics for ear pain with acute otitis media.
    International journal of pediatric otorhinolaryngology, 2022, Volume: 156

    Topics: Acetaminophen; Acute Disease; Analgesics; Anti-Bacterial Agents; Child; Child, Preschool; Earache; H

2022
    Praxis, 2018, Volume: 107, Issue:19

    Topics: Acute Disease; Adolescent; Adult; Amdinocillin Pivoxil; Double-Blind Method; Escherichia coli Infect

2018
Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2019, Volume: 25, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arctostaphylos; Com

2019
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
A randomized trial of colchicine for acute pericarditis.
    The New England journal of medicine, 2013, Oct-17, Volume: 369, Issue:16

    Topics: Acute Disease; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Aspirin; Colchicine; Double-Blind

2013
Efficacy of anti-inflammatory or antibiotic treatment in patients with non-complicated acute bronchitis and discoloured sputum: randomised placebo controlled trial.
    BMJ (Clinical research ed.), 2013, Oct-04, Volume: 347

    Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacteria

2013
Optic Nerve Sheath Diameter Increase on Ascent to High Altitude: Correlation With Acute Mountain Sickness.
    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2015, Volume: 34, Issue:9

    Topics: Acute Disease; Adult; Aged; Altitude Sickness; Causality; Comorbidity; Double-Blind Method; Female;

2015
Randomized double-blind placebo controlled crossover study of acetaminophen, ibuprofen, acetaminophen/hydrocodone, and placebo for the relief of pain from a standard painful stimulus.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:9

    Topics: Acetaminophen; Acute Disease; Analgesics; Cross-Over Studies; Double-Blind Method; Drug Combinations

2009
Paracetamol versus ibuprofen: a randomized controlled trial of outpatient analgesia efficacy for paediatric acute limb fractures.
    Emergency medicine Australasia : EMA, 2009, Volume: 21, Issue:6

    Topics: Acetaminophen; Acute Disease; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Analysis of Var

2009
Heat or cold packs for neck and back strain: a randomized controlled trial of efficacy.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:5

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Chi-Square Distribution; C

2010
Intravenous ibuprofen (IV-ibuprofen) controls fever effectively in adults with acute uncomplicated Plasmodium falciparum malaria but prolongs parasitemia.
    The American journal of tropical medicine and hygiene, 2010, Volume: 83, Issue:1

    Topics: Acute Disease; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Double-Blind Method; Drug Th

2010
Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-control
    Clinical therapeutics, 2010, Volume: 32, Issue:5

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents,

2010
Pain management in young children undergoing diagnostic tympanocentesis.
    Clinical pediatrics, 2011, Volume: 50, Issue:3

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Biopsy, Fine-Needle; Chi

2011
Effectiveness of anti-inflammatory treatment versus antibiotic therapy and placebo for patients with non-complicated acute bronchitis with purulent sputum. The BAAP Study protocol.
    BMC pulmonary medicine, 2011, Jun-21, Volume: 11

    Topics: Acute Disease; Adolescent; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents

2011
Children's ibuprofen suspension for the acute treatment of pediatric migraine.
    Headache, 2002, Volume: 42, Issue:8

    Topics: Acute Disease; Analgesics, Non-Narcotic; Child; Double-Blind Method; Female; Humans; Ibuprofen; Male

2002
A randomized, clinical trial comparing oral celecoxib 200 mg, celecoxib 400 mg, and ibuprofen 600 mg for acute pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2003, Volume: 10, Issue:1

    Topics: Acute Disease; Adult; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double

2003
Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.
    Journal of endodontics, 2003, Volume: 29, Issue:1

    Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase

2003
Overnight use of continuous low-level heatwrap therapy for relief of low back pain.
    Archives of physical medicine and rehabilitation, 2003, Volume: 84, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Demography; Disability Evaluation; Femal

2003
Effect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690].
    BMC cardiovascular disorders, 2003, Feb-06, Volume: 3

    Topics: Acetaminophen; Acute Disease; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroida

2003
Relief of acute low back pain with diclofenac-K 12.5 mg tablets: a flexible dose, ibuprofen 200 mg and placebo-controlled clinical trial.
    International journal of clinical pharmacology and therapeutics, 2003, Volume: 41, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind

2003
Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis.
    Annals of the rheumatic diseases, 2004, Volume: 63, Issue:7

    Topics: Acute Disease; Aged; Amino Acids; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Bio

2004
Rofecoxib versus ibuprofen for acute treatment of migraine: a randomised placebo controlled trial.
    Postgraduate medical journal, 2004, Volume: 80, Issue:950

    Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal;

2004
Rofecoxib in the acute treatment of migraine: a randomized controlled clinical trial.
    Headache, 2006, Volume: 46, Issue:2

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dizziness; Dose-Response Relationship

2006
Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain.
    Pain, 2007, Volume: 128, Issue:1-2

    Topics: Acute Disease; Adolescent; Adult; Anti-Inflammatory Agents; Cyclooxygenase 2 Inhibitors; Cytokines;

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
A randomized, controlled trial of acetaminophen, ibuprofen, and codeine for acute pain relief in children with musculoskeletal trauma.
    Pediatrics, 2007, Volume: 119, Issue:3

    Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics

2007
Rizatriptan vs. ibuprofen in migraine: a randomised placebo-controlled trial.
    The journal of headache and pain, 2007, Volume: 8, Issue:3

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Male; Migr

2007
[Clinical evaluation of sulindac (CLINORIL) in the treatment of acute upper respiratory tract infection--double-blind comparison with ibuprofen].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1983, Volume: 57, Issue:3

    Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Ibuprofen

1983
[Double blind controlled study of miroprofen in acute upper respiratory tract infections--comparison with ibuprofen].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1982, Volume: 56, Issue:5

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Doubl

1982
Clinical evaluation of H1-receptor and H2-receptor antagonists for acute postoperative pain.
    Journal of clinical pharmacology, 1993, Volume: 33, Issue:10

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Molar, Third; Pain, Post

1993
Penicillin as a supplement in resolving the localized acute apical abscess.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1996, Volume: 81, Issue:5

    Topics: Acute Disease; Analysis of Variance; Double-Blind Method; Humans; Ibuprofen; Pain Measurement; Penic

1996
Penicillin as a supplement in resolving the localized acute apical abscess.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1996, Volume: 81, Issue:5

    Topics: Acute Disease; Analysis of Variance; Double-Blind Method; Humans; Ibuprofen; Pain Measurement; Penic

1996
Penicillin as a supplement in resolving the localized acute apical abscess.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1996, Volume: 81, Issue:5

    Topics: Acute Disease; Analysis of Variance; Double-Blind Method; Humans; Ibuprofen; Pain Measurement; Penic

1996
Penicillin as a supplement in resolving the localized acute apical abscess.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1996, Volume: 81, Issue:5

    Topics: Acute Disease; Analysis of Variance; Double-Blind Method; Humans; Ibuprofen; Pain Measurement; Penic

1996
A randomized, double-blind, multicentre controlled trial of ibuprofen versus acetaminophen and placebo for symptoms of acute otitis media in children.
    Fundamental & clinical pharmacology, 1996, Volume: 10, Issue:4

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chi

1996
A study to compare ibuprofen effervescent granules with ibuprofen tablets in the treatment of acute dental pain.
    Primary dental care : journal of the Faculty of General Dental Practitioners (UK), 1994, Volume: 1, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi

1994
Intramuscular ketorolac vs oral ibuprofen in emergency department patients with acute pain.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 1998, Volume: 5, Issue:2

    Topics: Acute Disease; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho

1998
Effectiveness of ibuprofen-arginine in the treatment of acute migraine attacks.
    International journal of clinical pharmacology research, 1998, Volume: 18, Issue:3

    Topics: Acute Disease; Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Ster

1998
The safety of acetaminophen and ibuprofen among children younger than two years old.
    Pediatrics, 1999, Volume: 104, Issue:4

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Asthma; Bronchiolitis; Double-Blind Method;

1999
Assessment of the efficacy and safety of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections.
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:9

    Topics: Acetaminophen; Acute Disease; Adolescent; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Infla

1999
Treatment of acute low back pain with the COX-2-selective anti-inflammatory drug nimesulide: results of a randomized, double-blind comparative trial versus ibuprofen.
    Spine, 2000, Jun-15, Volume: 25, Issue:12

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 In

2000
The effectiveness of prophylactic etodolac on postendodontic pain.
    Journal of endodontics, 2000, Volume: 26, Issue:12

    Topics: Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammato

2000
Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain.
    Spine, 2002, May-15, Volume: 27, Issue:10

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Follow-Up Studies

2002
Prostaglandin-synthesis inhibitors in prophylaxis of food intolerance.
    Lancet (London, England), 1978, Apr-29, Volume: 1, Issue:8070

    Topics: Acute Disease; Adult; Animals; Aspirin; Bivalvia; Chickens; Clinical Trials as Topic; Dairy Products

1978
A double-blind study of ibuprofen versus placebo in the treatment of acute migraine attacks.
    Cephalalgia : an international journal of headache, 1992, Volume: 12, Issue:3

    Topics: Acute Disease; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; Migraine Di

1992
[Reaferon and interferonogenes in the therapy of acute viral hepatitis B].
    Klinicheskaia meditsina, 1991, Volume: 69, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Drug Therapy, Combination; Hepatitis B; Humans; Ibuprofen; I

1991
Benefits of early anti-inflammatory medication following acute ankle injury.
    Injury, 1989, Volume: 20, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Ankle Injuries; Bandages; Double-Blind Method; Humans; Ibuprofen;

1989
Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:11

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Mal

1989

Other Studies

92 other studies available for ibuprofen and Acute Disease

ArticleYear
Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Acute Disease; Analgesics; Animals; Bacteria; Diphenylacetic Acids; Female; Fungi; Hepatocytes; Ibup

2008
Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: synthesis and their anti-inflammatory and analgesic activities.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclizatio

2009
Ibuprofen Alleviates Acute Pancreatitis- (AP-) Induced Myocardial Injury by Inhibiting AIM2.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Acute Disease; Animals; DNA-Binding Proteins; Ibuprofen; Pancreatitis; Rats; Tumor Necrosis Factor-a

2022
Ibuprofen as risk-factor for complications of acute anterior sinusitis in children.
    European annals of otorhinolaryngology, head and neck diseases, 2020, Volume: 137, Issue:2

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Brain Diseases; Child; Child, Pr

2020
Does Ibuprofen Worsen COVID-19?
    Drug safety, 2020, Volume: 43, Issue:7

    Topics: Acute Disease; Angiotensin-Converting Enzyme 2; Anti-Inflammatory Agents, Non-Steroidal; Betacoronav

2020
Age- and sex-based differences in patients with acute pericarditis.
    European journal of clinical investigation, 2021, Volume: 51, Issue:3

    Topics: Acute Disease; Adult; Age Distribution; Age Factors; Aged; Anti-Inflammatory Agents; Anti-Inflammato

2021
Young child with painful edema and purpura: a case report.
    Italian journal of pediatrics, 2021, Mar-10, Volume: 47, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Edema; Hemorrhage;

2021
Decreased alertness due to sleep loss increases pain sensitivity in mice.
    Nature medicine, 2017, Volume: 23, Issue:6

    Topics: Acute Disease; Analgesics; Animals; Behavior, Animal; Benzhydryl Compounds; Caffeine; Chronic Diseas

2017
Pharmacological interventions for preventing acute mountain sickness: a network meta-analysis and trial sequential analysis of randomized clinical trials.
    Annals of medicine, 2018, Volume: 50, Issue:2

    Topics: Acetazolamide; Acute Disease; Altitude Sickness; Dexamethasone; Drug Administration Schedule; Drug T

2018
Response to Burtscher re: "Increased Cytokines at High Altitude: Lack of Effect of Ibuprofen on Acute Mountain Sickness, Physiological Variables, or Cytokine Levels".
    High altitude medicine & biology, 2018, Volume: 19, Issue:3

    Topics: Acute Disease; Altitude; Altitude Sickness; Cytokines; Humans; Ibuprofen

2018
Thalidomide protects against acute pentylenetetrazol and pilocarpine-induced seizures in mice.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:11

    Topics: 4-Aminopyridine; Acute Disease; Animals; Anticonvulsants; Disease Models, Animal; Drug Therapy, Comb

2018
Good prognosis for pericarditis with and without myocardial involvement: results from a multicenter, prospective cohort study.
    Circulation, 2013, Jul-02, Volume: 128, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal;

2013
Efficacy of antibiotics and non-steroidal anti-inflammatory drugs in non-complicated acute bronchitis.
    Internal and emergency medicine, 2014, Volume: 9, Issue:7

    Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Inflammato

2014
An Interesting Case of Viral Pericarditis.
    Pediatric emergency care, 2016, Volume: 32, Issue:5

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Dehydration; Diagnosis, Differen

2016
Chemotherapy Induced Acute Pericarditis in a Child.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25 Suppl 2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protoco

2015
Ibuprofen-induced acute interstitial nephritis in the paediatric population.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2016, Volume: 36, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Child; Humans; Ibuprofen; Nephritis, Interst

2016
Acute interstitial nephritis due to flecainide therapy in the 38(th) week of pregnancy.
    BMC nephrology, 2016, Mar-15, Volume: 17

    Topics: Acute Disease; Acute Kidney Injury; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal;

2016
Acute gonadal vein thrombosis secondary to terminal ileitis and thrombophilia.
    The Journal of urology, 2008, Volume: 180, Issue:3

    Topics: Acute Disease; Adult; Diagnosis, Differential; Fluid Therapy; Humans; Ibuprofen; Ileitis; Ketorolac

2008
Acute localized exanthematous pustulosis (ALEP) caused by Ibuprofen. A case report.
    The British journal of oral & maxillofacial surgery, 2009, Volume: 47, Issue:2

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Drug Eruptions; Exanthema; Facial Dermatoses

2009
Novel presentation of acute pericarditis in an Ironman triathlete.
    Current sports medicine reports, 2007, Volume: 6, Issue:3

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Confusion; Cough; Dyspnea; Electrocar

2007
Management of acute postpartum pain in patients maintained on methadone or buprenorphine during pregnancy.
    The American journal of drug and alcohol abuse, 2009, Volume: 35, Issue:3

    Topics: Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Buprenorphine; Controlled Clinic

2009
Excessive acute migraine medication use and migraine progression.
    Neurology, 2009, Sep-01, Volume: 73, Issue:9

    Topics: Acute Disease; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Barbiturates

2009
A case of acute myocarditis caused by pandemic (H1N1) 2009 influenza virus.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2010, Volume: 109, Issue:11

    Topics: Acute Disease; Adolescent; Electrocardiography; Humans; Ibuprofen; Influenza A Virus, H1N1 Subtype;

2010
Acute pericarditis due to pegylated interferon alpha therapy for chronic HCV hepatitis - case report.
    BMC gastroenterology, 2011, Mar-31, Volume: 11

    Topics: Acute Disease; Adult; Antiviral Agents; Female; Hepatitis C, Chronic; Humans; Ibuprofen; Interferon

2011
Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation properties of new 2-(4-isobutylphenyl)propanoic acid derivatives.
    Journal of enzyme inhibition and medicinal chemistry, 2012, Volume: 27, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Dise

2012
Acute earache.
    Canadian family physician Medecin de famille canadien, 2011, Volume: 57, Issue:9

    Topics: Acute Disease; Amoxicillin; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child, Preschool; Earac

2011
A case of acute constrictive pericarditis associated with Behçet's disease.
    International journal of rheumatic diseases, 2011, Volume: 14, Issue:4

    Topics: Acute Disease; Azathioprine; Behcet Syndrome; Colchicine; Drug Therapy, Combination; Humans; Ibuprof

2011
Acute pericarditis associated to onset of diabetes mellitus.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Acute Disease; Adult; Colchicine; Diabetic Ketoacidosis; Drug Therapy, Combination; Electrocardiogra

2012
Acute calcific tendinitis of the wrist.
    The Journal of emergency medicine, 2013, Volume: 44, Issue:2

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Calcinosis; Chills; Edema

2013
Hepatic metabolism of ibuprofen in rats under acute hypobaric hypoxia.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:6

    Topics: Acute Disease; Altitude; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytochrome P-450 Enzyme S

2013
Augmentation of analgesic effect of ibuprofen by alprazolam in experimental model of pain.
    Physiological research, 2002, Volume: 51, Issue:2

    Topics: Acetic Acid; Acute Disease; Administration, Oral; Alprazolam; Analgesics, Non-Narcotic; Animals; Dis

2002
Chronic hepatitis C, ibuprofen, and liver damage.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:7

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Hepa

2002
Ibuprofen and psychotic exacerbation.
    The American journal of psychiatry, 2002, Volume: 159, Issue:9

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Back Pain; Como

2002
Unintentional overdose of analgesia secondary to acute dental pain.
    British dental journal, 2002, Aug-24, Volume: 193, Issue:4

    Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents,

2002
[Gastrointestinal hemorrhages as complications of gastropathies associated with intake of nonsteroidal anti-inflammatory drugs].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:5

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Duodenal Ulcer; Duodeno

2003
COX expression and PGE(2) and PGD(2) production in experimental acute and chronic gastric lesions.
    International immunopharmacology, 2005, Volume: 5, Issue:2

    Topics: Acetic Acid; Acute Disease; Animals; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxyge

2005
Acute purulent pericarditis in pneumococcal meningitis.
    Intensive care medicine, 2005, Volume: 31, Issue:8

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Menin

2005
Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2006, Volume: 29, Issue:1

    Topics: Acute Disease; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Combi

2006
[Acute pericarditis: results of a survey of treatment practices of cardiologists].
    Archives des maladies du coeur et des vaisseaux, 2006, Volume: 99, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents; Aspirin; Colchicine; France; Hospitalization; Humans; Ibupr

2006
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain.
    Pain, 2006, Volume: 121, Issue:1-2

    Topics: Acute Disease; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic A

2006
Efficacy and safety of acupuncture for the treatment of non-specific acute low back pain: a randomised controlled multicentre trial protocol [ISRCTN65814467].
    BMC complementary and alternative medicine, 2006, Apr-21, Volume: 6

    Topics: Acetaminophen; Acupuncture; Acute Disease; Adult; Amitriptyline; Analgesics; Bayes Theorem; Clinical

2006
A case of probable ibuprofen-induced acute pancreatitis.
    JOP : Journal of the pancreas, 2006, May-09, Volume: 7, Issue:3

    Topics: Acute Disease; Adolescent; Drug Overdose; Humans; Ibuprofen; Male; Pancreatitis

2006
Analgesic activity of Ugni molinae (murtilla) in mice models of acute pain.
    Journal of ethnopharmacology, 2007, May-30, Volume: 112, Issue:1

    Topics: Acute Disease; Analgesics; Animals; Flavonoids; Glycosides; Ibuprofen; Male; Mice; Myrtaceae; Pain;

2007
[Acute retinal pigment epitheliitis: a case report].
    Archivos de la Sociedad Espanola de Oftalmologia, 2007, Volume: 82, Issue:7

    Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Electrooculography; Fluorescein Angiography;

2007
[Diffuse interstitial pneumonitis with acute respiratory failure].
    Revue de pneumologie clinique, 2007, Volume: 63, Issue:3

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Bronchoscopy; Female; Humans; Ibuprof

2007
[Ambulatory pain management for children in the family practice].
    MMW Fortschritte der Medizin, 2007, Jul-19, Volume: 149, Issue:29-30

    Topics: Acetaminophen; Acute Disease; Ambulatory Care; Analgesics; Analgesics, Opioid; Child; Chronic Diseas

2007
Non-steroidal anti-inflammatory drugs-associated acute interstitial nephritis with granular tubular basement membrane deposits.
    Pediatric nephrology (Berlin, Germany), 2008, Volume: 23, Issue:1

    Topics: Acute Disease; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Basement Membrane; Huma

2008
Effects of ibuprofen on a porcine model of acute respiratory failure.
    The Journal of surgical research, 1984, Volume: 36, Issue:4

    Topics: Acute Disease; Animals; Disease Models, Animal; Hemodynamics; Ibuprofen; Lung; Male; Pseudomonas Inf

1984
Acute poisoning with ibuprofen.
    Human toxicology, 1983, Volume: 2, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Child; Child, Preschool; Chlorpheniramine; Diazepam; Female;

1983
Experimental evidence for involvement of prostaglandins in viability and acute skin flaps: effects on viability and mode of action.
    Plastic and reconstructive surgery, 1981, Volume: 67, Issue:3

    Topics: Abdomen; Acute Disease; Animals; Ibuprofen; Indomethacin; Male; Mathematics; Prostaglandins; Rats; S

1981
Effects of flurbiprofen on myocardial cell damage in acute myocardial ischemia.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 28, Issue:3

    Topics: Acute Disease; Animals; Blood Pressure; Cats; Cell Membrane; Coronary Disease; Creatine Kinase; Elec

1980
Effect of ibuprofen treatment during experimental acute otitis media.
    Auris, nasus, larynx, 1995, Volume: 22, Issue:2

    Topics: Acute Disease; Ampicillin; Animals; Chinchilla; Drug Therapy, Combination; Ear, Middle; Fatty Acids,

1995
Treatment of experimental acute otitis media with ibuprofen and ampicillin.
    International journal of pediatric otorhinolaryngology, 1995, Volume: 33, Issue:2

    Topics: Acute Disease; Ampicillin; Animals; Chinchilla; Disease Models, Animal; Drug Therapy, Combination; E

1995
[Interstitial nephritis caused by non-steroidal anti-inflammatory agents--report of 2 cases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1995, Apr-10, Volume: 84, Issue:4

    Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diclofenac; Fe

1995
NSAID use and efficacy in the emergency department: single doses of oral ibuprofen versus intramuscular ketorolac.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:3

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-St

1994
Role of prostaglandins and nitric oxide in acute inflammatory reactions in guinea-pig skin.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Acute Disease; Alprostadil; Animals; Arginine; Dermatitis; Edema; Female; Guinea Pigs; Ibuprofen; Le

1993
Drug-induced pulmonary edema in a patient infected with human immunodeficiency virus.
    Chest, 1993, Volume: 104, Issue:3

    Topics: Acute Disease; Adult; AIDS-Related Opportunistic Infections; Diagnosis, Differential; HIV Infections

1993
Biocompatibility of hemodialysis membranes: evaluation in an ovine model.
    The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:2

    Topics: Acute Disease; Acute-Phase Reaction; Animals; Bicarbonates; Blood Gas Analysis; Complement Activatio

1993
Ibuprofen does not suppress active multiple sclerosis lesions on gadolinium-enhanced MR images.
    Annals of neurology, 1997, Volume: 42, Issue:6

    Topics: Acute Disease; Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combin

1997
Acute interstitial nephritis due to over-the-counter ibuprofen in a renal transplant recipient.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:1

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Ibuprofen; Kidney Tra

1998
Management of pain in endodontic patients.
    Texas dental journal, 1997, Volume: 114, Issue:10

    Topics: Acute Disease; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Codeine; Dental Pulp Dis

1997
Influence of acute uraemia on percutaneous absorption of nonsteroidal anti-inflammatory drugs.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1998, Volume: 141

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Ibuprofen; Indomethacin

1998
Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child.
    Gastroenterology, 1998, Volume: 115, Issue:3

    Topics: Acute Disease; Adult; Bile Duct Diseases; Biopsy; Child; Cholestasis; Female; Humans; Ibuprofen; Liv

1998
The role of prostanoids and nitric oxide in endotoxin-induced hyporesponsiveness of equine digital blood vessels.
    Equine veterinary journal, 1999, Volume: 31, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Culture Techniques; Cycloheximide; Cyclooxygen

1999
The risk of acute major upper gastrointestinal bleeding among users of aspirin and ibuprofen at various levels of alcohol consumption.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Acute Disease; Aged; Alcohol Drinking; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Case-Contro

1999
Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain.
    Journal of pain and symptom management, 1999, Volume: 18, Issue:6

    Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Double-Blind Method; Humans; Ibuprofen; Pain

1999
Acute erosive gastritis induced by aspirin, ketoprofen, ibuprofen, and naproxen: its prevention by metiamide and cimetidine.
    Southern medical journal, 1977, Volume: 70, Issue:5

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastritis;

1977
Acute adverse reactions to ibuprofen in systemic lupus erythematosus.
    JAMA, 1979, Jun-15, Volume: 241, Issue:24

    Topics: Acute Disease; Adult; Arthritis; Drug Hypersensitivity; Female; Fever; Headache; Humans; Hypotension

1979
Beneficial effects of ibuprofen in acute myocardial ischemia.
    Cardiology, 1979, Volume: 64, Issue:5

    Topics: Acute Disease; Animals; Cathepsins; Cats; Coronary Disease; Creatine Kinase; Drug Evaluation, Precli

1979
Ibuprofen in the treatment of acute gouty arthritis.
    JAMA, 1978, Jan-02, Volume: 239, Issue:1

    Topics: Acute Disease; Administration, Oral; Adult; Aged; Drug Tolerance; Gout; Humans; Ibuprofen; Male; Mid

1978
The neutrophil respiratory burst and tissue injury in septic acute lung injury: the effect of cyclooxygenase inhibition in swine.
    Surgery, 1992, Volume: 112, Issue:1

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Capillaries; Ibuprofen; Kinetics; Leukocyte Co

1992
Effect of age on ibuprofen pharmacokinetics and antipyretic response.
    The Journal of pediatrics, 1992, Volume: 121, Issue:6

    Topics: Acute Disease; Aging; Axilla; Body Temperature; Child; Child, Preschool; Drug Evaluation; Female; Fe

1992
[The results of the endoscopic diathermy coagulation of hemorrhaging gastroduodenal ulcers].
    Khirurgiia, 1992, Issue:2

    Topics: Acute Disease; Duodenal Ulcer; Electrocoagulation; Female; Hemostasis, Endoscopic; Humans; Ibuprofen

1992
Bleeding tendency, platelet function, and pharmacokinetics of ibuprofen and zidovudine in HIV(+) hemophilic men.
    American journal of hematology, 1992, Volume: 40, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Bleeding Time; Blood Platelets; Chronic Disease; Drug Therapy, Com

1992
Ibuprofen attenuates plasma tumor necrosis factor activity during sepsis-induced acute lung injury.
    Journal of applied physiology (Bethesda, Md. : 1985), 1991, Volume: 71, Issue:3

    Topics: Acute Disease; Animals; Blood Gas Analysis; Blood Pressure; Cardiac Output; Extravascular Lung Water

1991
Ibuprofen prevents deterioration in static transpulmonary compliance and transalveolar protein flux in septic porcine acute lung injury.
    The Journal of trauma, 1991, Volume: 31, Issue:2

    Topics: Acute Disease; Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Capillary Permeability; Extrav

1991
Acute central nervous system symptoms caused by ibuprofen in connective tissue disease.
    The Journal of rheumatology, 1990, Volume: 17, Issue:8

    Topics: Acute Disease; Adult; Central Nervous System Diseases; Connective Tissue Diseases; Drug Hypersensiti

1990
Lofgren's syndrome (acute sarcoidosis) sine erythema nodosum mimicking acute rheumatoid arthritis.
    New York state journal of medicine, 1990, Volume: 90, Issue:9

    Topics: Acute Disease; Adult; Arthritis; Arthritis, Rheumatoid; Diagnosis, Differential; Erythema Nodosum; F

1990
[Immediate hypersensitivity reaction in acute viral hepatitis A and B treated with interferon inducers].
    Sovetskaia meditsina, 1989, Issue:11

    Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Aged; Hepatitis A; Hepatitis B; Humans; Hy

1989
Asthma death due to ibuprofen.
    Lancet (London, England), 1987, May-09, Volume: 1, Issue:8541

    Topics: Acute Disease; Aged; Albuterol; Asthma; Beclomethasone; Drug Interactions; Female; Humans; Ibuprofen

1987
Effects of ibuprofen on neutrophil function and acute lung injury in canine endotoxin shock.
    Critical care medicine, 1988, Volume: 16, Issue:11

    Topics: Acute Disease; Animals; Bronchoalveolar Lavage Fluid; Cell Adhesion; Dogs; Dose-Response Relationshi

1988
[Use of interferon inducers and reaferon in the combined therapy of acute viral hepatitis B].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Aged; Antibody Formation; Drug Evaluation; Drug Therapy, Combinati

1988
[Content of total immunoglobulin E of the blood serum in patients with acute viral hepatitis A and B undergoing prodigiozan and ibuprofen treatment].
    Sovetskaia meditsina, 1988, Issue:12

    Topics: Acute Disease; Drug Evaluation; Drug Therapy, Combination; Hepatitis A; Hepatitis B; Humans; Ibuprof

1988
Prostacyclin and thromboxane in acute hemorrhagic pancreatitis in dogs.
    The Journal of surgical research, 1987, Volume: 42, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Blood Pressure; Dogs; Epoprostenol; Hemorrhage

1987
[Experimental study of the antihypoxic properties of ibuprofen and other nonsteroidal anti-inflammatory preparations].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:6

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Asphyxia; Drug Evaluation, Preclini

1987
Reversible acute decrease in renal function by NSAIDs in cirrhosis.
    The American journal of the medical sciences, 1987, Volume: 294, Issue:3

    Topics: Acute Disease; Creatinine; Female; Humans; Ibuprofen; Indenes; Kidney; Liver Cirrhosis, Alcoholic; M

1987
Acute metabolic acidosis due to ibuprofen overdose.
    Journal of the Mississippi State Medical Association, 1987, Volume: 28, Issue:9

    Topics: Acidosis; Acute Disease; Female; Humans; Ibuprofen; Infant

1987
Nonsteroidal anti-inflammatory drugs and acute cortical necrosis.
    Annals of internal medicine, 1986, Volume: 105, Issue:2

    Topics: Acute Disease; Aged; Female; Humans; Ibuprofen; Kidney Cortex Necrosis; Male

1986
[Acute pulmonary hypertension treated with ibuprofen].
    Ugeskrift for laeger, 1986, Sep-29, Volume: 148, Issue:40

    Topics: Acute Disease; Aged; Humans; Hypertension, Pulmonary; Ibuprofen; Male; Pulmonary Embolism

1986
Limited effects of prostaglandin inhibitors in Escherichia coli sepsis.
    Surgery, 1985, Volume: 98, Issue:2

    Topics: Acute Disease; Animals; Body Temperature; Disease Models, Animal; Dogs; Escherichia coli Infections;

1985
Effect of prostaglandin blockers on ascites fluid in pancreatitis.
    Surgery, 1985, Volume: 98, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Animals; Ascitic Fluid; Biological Assay; Electrolytes;

1985
Nephrotoxicity from nonsteroidal anti-inflammatory drugs.
    Southern medical journal, 1985, Volume: 78, Issue:3

    Topics: Acute Disease; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Aspirin; Female; Humans; Hyperka

1985