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ibuprofen and Acidosis

ibuprofen has been researched along with Acidosis in 19 studies

Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
"To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose."7.69Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995)
"A 21-month-old boy developed acute renal failure with severe metabolic acidosis after ingestion of ibuprofen 8 g."7.69Hypocalcemia and hypomagnesemia after ibuprofen overdose. ( al-Harbi, NN; Domrongkitchaiporn, S; Lirenman, DS, 1997)
"Ibuprofen was the first over-the-counter nonsteroidal anti-inflammatory drug available in the United States."5.36Polyuria, acidosis, and coma following massive ibuprofen ingestion. ( Khurana, A; Levine, M; Ruha, AM, 2010)
"To report a child who developed shock, loss of consciousness, and metabolic acidosis following an ibuprofen overdose."3.69Shock, metabolic acidosis, and coma following ibuprofen overdose in a child. ( Uy, CC; Zuckerman, GB, 1995)
"A 21-month-old boy developed acute renal failure with severe metabolic acidosis after ingestion of ibuprofen 8 g."3.69Hypocalcemia and hypomagnesemia after ibuprofen overdose. ( al-Harbi, NN; Domrongkitchaiporn, S; Lirenman, DS, 1997)
"Ibuprofen was the first over-the-counter nonsteroidal anti-inflammatory drug available in the United States."1.36Polyuria, acidosis, and coma following massive ibuprofen ingestion. ( Khurana, A; Levine, M; Ruha, AM, 2010)
"The patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care."1.31Massive ibuprofen ingestion with survival. ( Bronstein, AC; McGuire, T; Seifert, SA, 2000)
"Ibuprofen pretreatment increases arterial pressure and reduces mortality in endotoxic dogs."1.28Cardiovascular response in canine endotoxic shock: effect of ibuprofen pretreatment. ( Pinsky, MR, 1992)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's7 (36.84)18.2507
2000's3 (15.79)29.6817
2010's5 (26.32)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chávez-Iñiguez, JS1
Espinosa-García, F1
Pacheco-Plascencia, A1
Andrade-Sierra, J1
Rubio-Reynoso, R1
García-García, G1
Akingbola, OA1
Singh, D1
Kleinman, JA1
Frieberg, EM1
Arens, A1
Smollin, C1
Levine, M1
Khurana, A1
Ruha, AM1
McWhirter, KA1
Jones, RB1
Zawada, ET1
Le, HT1
Bosse, GM1
Tsai, Y1
Downie, A1
Ali, A1
Bell, D1
Fletcher, JR1
Collins, JN1
Graves, ED1
Luterman, A1
Williams, MD1
Izenberg, SD1
Rodning, CB1
Zuckerman, GB1
Uy, CC1
al-Harbi, NN1
Domrongkitchaiporn, S1
Lirenman, DS1
Seifert, SA1
Bronstein, AC1
McGuire, T1
Easley, RB1
Altemeier, WA1
Steen, AE1
Reeh, PW1
Geisslinger, G1
Steen, KH1
Pinsky, MR1
Page, RD1
Yorio, T1
Linden, CH1
Townsend, PL1
Primos, W1
Bhatnager, A1
Bishop, P1
Evans, OB1
Lee, CY1
Finkler, A1

Reviews

2 reviews available for ibuprofen and Acidosis

ArticleYear
Renal consequences of nonsteroidal antiinflammatory drugs.
    Postgraduate medicine, 1982, Volume: 71, Issue:5

    Topics: Acidosis; Acute Kidney Injury; Aged; Anti-Inflammatory Agents; Bartter Syndrome; Female; Humans; Hyp

1982
Metabolic acidosis after acute ibuprofen overdosage.
    The Journal of pediatrics, 1987, Volume: 111, Issue:6 Pt 1

    Topics: Acidosis; Child, Preschool; Humans; Ibuprofen; Infant; Male

1987

Trials

1 trial available for ibuprofen and Acidosis

ArticleYear
Plasma levels after peroral and topical ibuprofen and effects upon low pH-induced cutaneous and muscle pain.
    European journal of pain (London, England), 2000, Volume: 4, Issue:2

    Topics: Acidosis; Acids; Administration, Cutaneous; Administration, Oral; Adult; Anti-Inflammatory Agents, N

2000

Other Studies

16 other studies available for ibuprofen and Acidosis

ArticleYear
The Case | Severe hypokalemia and metabolic acidosis.
    Kidney international, 2018, Volume: 93, Issue:5

    Topics: Acidosis; Acidosis, Renal Tubular; Adult; Analgesics, Non-Narcotic; Biomarkers; Humans; Hypokalemia;

2018
Functional adrenal insufficiency complicating an overdose of naproxen and ibuprofen.
    Clinical pediatrics, 2015, Volume: 54, Issue:1

    Topics: Acidosis; Adolescent; Adrenal Insufficiency; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non

2015
Case Files of the University of California, San Francisco Medical Toxicology Fellowship: Seizures and a Persistent Anion Gap Metabolic Acidosis.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2016, Volume: 12, Issue:3

    Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose;

2016
Polyuria, acidosis, and coma following massive ibuprofen ingestion.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2010, Volume: 6, Issue:3

    Topics: Acidosis; Adult; Anti-Inflammatory Agents, Non-Steroidal; Coma; Humans; Ibuprofen; Male; Polyuria

2010
Accidental overdose of proprietary branded, combination analgesics available over the counter.
    British journal of hospital medicine (London, England : 2005), 2012, Volume: 73, Issue:11

    Topics: Acidosis; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Codeine; Di

2012
Ibuprofen overdose complicated by renal failure, adult respiratory distress syndrome, and metabolic acidosis.
    Journal of toxicology. Clinical toxicology, 1994, Volume: 32, Issue:3

    Topics: Acidosis; Acute Kidney Injury; Adult; Charcoal; Citrates; Citric Acid; Drug Overdose; Humans; Ibupro

1994
Severe metabolic acidosis complicating massive ibuprofen overdose.
    Postgraduate medical journal, 1993, Volume: 69, Issue:813

    Topics: Acidosis; Adult; Charcoal; Drug Overdose; Humans; Ibuprofen; Male

1993
Tumor necrosis factor-induced mortality is reversed with cyclooxygenase inhibition.
    Annals of surgery, 1993, Volume: 217, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Acidosis; Animals; Antibodies, Monoclonal; Bicarbonates; Blood Pressur

1993
Shock, metabolic acidosis, and coma following ibuprofen overdose in a child.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:9

    Topics: Acidosis; Child; Coma; Critical Care; Drug Overdose; Humans; Ibuprofen; Male; Shock

1995
Hypocalcemia and hypomagnesemia after ibuprofen overdose.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:4

    Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Drug Overdose; Humans; Hypocalcemia; Ibuprofen; I

1997
Massive ibuprofen ingestion with survival.
    Journal of toxicology. Clinical toxicology, 2000, Volume: 38, Issue:1

    Topics: Acidosis; Adolescent; Analgesics, Non-Narcotic; Coma; Drug Overdose; Female; Humans; Ibuprofen; Thro

2000
Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.
    Pediatric emergency care, 2000, Volume: 16, Issue:1

    Topics: Acidosis; Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Central Nervous System; Central Nervou

2000
Cardiovascular response in canine endotoxic shock: effect of ibuprofen pretreatment.
    Circulatory shock, 1992, Volume: 37, Issue:4

    Topics: Acidosis; Animals; Disease Models, Animal; Dogs; Hemodynamics; Ibuprofen; Lactates; Lactic Acid; Oxy

1992
Prostaglandin F2 alpha inhibits acidification in H(+)-secreting epithelia.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Acidosis; Animals; Dinoprost; Drug Interactions; Epithelium; Hydrogen; Hydrogen-Ion Concentration; I

1990
Acute metabolic acidosis due to ibuprofen overdose.
    Journal of the Mississippi State Medical Association, 1987, Volume: 28, Issue:9

    Topics: Acidosis; Acute Disease; Female; Humans; Ibuprofen; Infant

1987
Acute intoxication due to ibuprofen overdose.
    Archives of pathology & laboratory medicine, 1986, Volume: 110, Issue:8

    Topics: Acidosis; Acute Kidney Injury; Adult; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; I

1986