ibuprofen has been researched along with Abortion, Tubal in 4 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied." | 8.02 | First trimester naproxen exposure and outcome of pregnancy - A German case series. ( Dathe, K; Fietz, AK; Hultzsch, S; Padberg, S; Paulus, W; Schaefer, C, 2021) |
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 7.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| " Only one study found evidence of an effect between interventions on pain score: a prophylactic dose of ibuprofen 1600 mg likely reduces the pain score when compared to a dose of paracetamol 2000 mg (mean difference (MD) 2." | 5.22 | Pain management for medical abortion before 14 weeks' gestation. ( Cameron, S; Morroni, C; Reynolds-Wright, JJ; Woldetsadik, MA, 2022) |
| "In contrast to other non-steroidal anti-inflammatory drugs (NSAIDs), naproxen use during pregnancy is not well studied." | 4.02 | First trimester naproxen exposure and outcome of pregnancy - A German case series. ( Dathe, K; Fietz, AK; Hultzsch, S; Padberg, S; Paulus, W; Schaefer, C, 2021) |
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 3.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reynolds-Wright, JJ | 1 |
| Woldetsadik, MA | 1 |
| Morroni, C | 1 |
| Cameron, S | 1 |
| Hultzsch, S | 2 |
| Paulus, W | 1 |
| Padberg, S | 2 |
| Fietz, AK | 2 |
| Schaefer, C | 2 |
| Dathe, K | 2 |
| Pritchard, LW | 1 |
| Meixner, K | 1 |
| Meister, R | 1 |
| Daniel, S | 1 |
| Koren, G | 1 |
| Lunenfeld, E | 1 |
| Levy, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylactic Pregabalin to Decrease Pain During Medical Abortion: a Randomized Controlled Trial[NCT02782169] | Phase 4 | 110 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| PAIN CONTROL IN FIRST TRIMESTER MEDICAL ABORTION: A Randomized Trial[NCT01457521] | Phase 4 | 250 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| The Effect of Prophylactic Ibuprofen Versus Placebo on Pain Relief and Success Rates of Medical Abortion: A Double-blind Randomized Placebo Controlled Study[NCT00997074] | Phase 3 | 61 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
reported on an 11-point numerical rating scale (NRS 0-10) where 0 indicates no pain and 10 indicates the most severe pain (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | units on a scale (Mean) |
|---|---|
| Pregabalin | 5.0 |
| Placebo | 5.5 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | tablets (Median) |
|---|---|
| Pregabalin | 1 |
| Placebo | 2 |
summed number of tablets used by each participant over the 72 hour study period (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | tablets (Median) |
|---|---|
| Pregabalin | 0 |
| Placebo | 0.5 |
A participant was included once if they ever reported a symptom during the 72 hour study period, not reflective of how long the symptom lasted. These were all commonly reported side effects during previous research on medication abortions and commonly reported side effects of pregabalin, so they were not included as adverse events. (NCT02782169)
Timeframe: Over 72 hours (measured at 0, 2, 6, 12, 24, and 72 hours)
| Intervention | participants (Number) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nausea | Vomiting | Sleepiness | Dizziness | Headache | Blurred Vision | Diarrhea | Constipation | Dry Mouth | |
| Placebo | 42 | 30 | 39 | 26 | 17 | 7 | 29 | 15 | 25 |
| Pregabalin | 43 | 28 | 47 | 45 | 28 | 15 | 28 | 6 | 22 |
Participant pain was assessed using an 11-point Visual Analog Scale for Pain. Scores ranged from 0 (no pain) to 10 (worst pain possible) (NCT01457521)
Timeframe: 1-2 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Prophylactic | 7.1 |
| Therapeutic | 7.3 |
1 review available for ibuprofen and Abortion, Tubal
| Article | Year |
|---|---|
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
Pain management for medical abortion before 14 weeks' gestation.
Topics: Abortion, Induced; Abortion, Spontaneous; Acetaminophen; Female; Humans; Ibuprofen; Mifepristone; Mi | 2022 |
3 other studies available for ibuprofen and Abortion, Tubal
| Article | Year |
|---|---|
First trimester naproxen exposure and outcome of pregnancy - A German case series.
Topics: Abortion, Spontaneous; Anencephaly; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Female; | 2021 |
No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Analgesics; Anti-Inflammatory Agents, Non-Steroi | 2018 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Femal | 2015 |