ibuprofen has been researched along with Abnormalities, Drug-Induced in 8 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 7.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| "Ibuprofen is an analgesic frequently used in the 1st and 2nd trimester of pregnancy." | 3.88 | No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort. ( Dathe, K; Fietz, AK; Hultzsch, S; Meister, R; Meixner, K; Padberg, S; Pritchard, LW; Schaefer, C, 2018) |
| "Ingestion of the anticonvulsant drug valproic acid and of the angiotensin converting enzyme inhibitor captopril during pregnancy has been associated with abnormal fetal outcome in humans." | 3.69 | Evaluation of the rat embryo culture system as a predictive test for human teratogens. ( Buttar, HS; Guest, I; Smith, S; Varma, DR, 1994) |
| "Ibuprofen is a non-selective cyclooxygenase (COX) inhibitor with analgesic, antipyretic and antiinflammatory activity." | 2.41 | [Current opinions on embryotoxic and teratogenic effects of ibuprofen]. ( Bełzek, A; Burdan, F, 2001) |
| " Unlike general toxicity data, their prenatal toxic effects were not extensively studied before." | 1.33 | Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study. ( Burdan, F, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dathe, K | 1 |
| Fietz, AK | 1 |
| Pritchard, LW | 1 |
| Padberg, S | 1 |
| Hultzsch, S | 2 |
| Meixner, K | 1 |
| Meister, R | 1 |
| Schaefer, C | 2 |
| Burdan, F | 2 |
| Cappon, GD | 1 |
| Fleeman, TL | 1 |
| Cook, JC | 1 |
| Hurtt, ME | 1 |
| Guest, I | 1 |
| Buttar, HS | 1 |
| Smith, S | 1 |
| Varma, DR | 1 |
| Kosar, K | 1 |
| Bełzek, A | 1 |
| Randall, CL | 1 |
| Becker, HC | 1 |
| Anton, RF | 1 |
2 reviews available for ibuprofen and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
[Analgesic drugs during pregnancy].
Topics: Abnormalities, Drug-Induced; Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anticonvulsa | 2016 |
[Current opinions on embryotoxic and teratogenic effects of ibuprofen].
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastroschisis; Humans; | 2001 |
6 other studies available for ibuprofen and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
No evidence of adverse pregnancy outcome after exposure to ibuprofen in the first trimester - Evaluation of the national Embryotox cohort.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Analgesics; Anti-Inflammatory Agents, Non-Steroi | 2018 |
Comparison of developmental toxicity of selective and non-selective cyclooxygenase-2 inhibitors in CRL:(WI)WUBR Wistar rats--DFU and piroxicam study.
Topics: Abdominal Wall; Abnormalities, Drug-Induced; Alanine Transaminase; Animals; Aspartate Aminotransfera | 2005 |
Combined treatment potentiates the developmental toxicity of ibuprofen and acetazolamide in rats.
Topics: Abnormalities, Drug-Induced; Acetazolamide; Animals; Animals, Newborn; Birth Weight; Body Weight; Ca | 2005 |
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Nega | 1994 |
Interaction of ibuprofen with early chick embryogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Embryo, Mammalian; Embryo, Nonmammalian; Embryon | 1993 |
Effect of ibuprofen on alcohol-induced teratogenesis in mice.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Aspirin; Body Weight; Ethanol; Female; F | 1991 |