ibudilast has been researched along with Muscle Contraction in 6 studies
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibudilast did not inhibit 12-deoxyphorbol 13-isobutyrate (DPB)-induced contraction in the presence of verapamil." | 1.34 | Ibudilast-induced decreases in cytosolic Ca(2+) level and contraction in rat aorta. ( Kaneda, T; Konno, Y; Nakajyo, S; Shimizu, K; Urakawa, N, 2007) |
| "Ibudilast was equipotent to attenuate the precontractions induced by both 0." | 1.31 | Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle. ( Ishii, K; Mitani, A; Moriuchi, H; Nakahara, T; Sakamoto, K; Yunoki, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tada, M | 1 |
| Chiba, K | 1 |
| Takakuwa, T | 1 |
| Kojima, E | 1 |
| Nakahara, T | 1 |
| Yunoki, M | 1 |
| Moriuchi, H | 1 |
| Mitani, A | 1 |
| Sakamoto, K | 1 |
| Ishii, K | 1 |
| Kaneda, T | 1 |
| Konno, Y | 1 |
| Urakawa, N | 1 |
| Nakajyo, S | 1 |
| Shimizu, K | 1 |
| Nagai, H | 2 |
| Iwamoto, T | 1 |
| Nishiyori, T | 1 |
| Takizawa, T | 1 |
| Tsuchiya, H | 1 |
| Koda, A | 1 |
| Ohashi, M | 2 |
| Kanai, R | 1 |
| Nishino, K | 1 |
| Sato, T | 2 |
| Takayanagi, I | 2 |
| Koike, K | 1 |
| Hisayama, T | 1 |
| Iwasaki, S | 1 |
6 other studies available for ibudilast and Muscle Contraction
| Article | Year |
|---|---|
Analogues of natural phloroglucinols as antagonists against both thromboxane A2 and leukotriene D4.
Topics: Animals; Guinea Pigs; Molecular Structure; Muscle Contraction; Phloroglucinol; SRS-A; Structure-Acti | 1992 |
Relaxation and potentiation of cGMP-mediated response by ibudilast in bovine tracheal smooth muscle.
Topics: Albuterol; Analysis of Variance; Animals; Atrial Natriuretic Factor; Bronchodilator Agents; Cattle; | 2002 |
Ibudilast-induced decreases in cytosolic Ca(2+) level and contraction in rat aorta.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aorta, Thoracic; Calcium; Cyclic AMP; Cyclic GMP; Cytosol; Dos | 2007 |
Pharmacological studies on newly synthesized anti-allergic agents, 2-methyl-3-piperidino-beta-propionaphtone hydrochloride (KZ-111) and 3-isobutyryl-2-isopropylpyrazole-[1, 5-a] pyridine (KC-404).
Topics: Animals; Asthma; Chromones; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Hypersensitivi | 1983 |
Antagonistic effect of KC-404, a new anti-asthmatic agent, on leukotriene D4-induced contractile responses in isolated guinea pig smooth muscles.
Topics: Acetylcholine; Animals; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Lung; Male; | 1986 |
Anti-leukotriene D4 action of a new anti-asthmatic drug (KC-404) on the guinea-pig isolated trachea.
Topics: Animals; Calcium Chloride; Cecum; Flurbiprofen; Guinea Pigs; Histamine; In Vitro Techniques; Male; M | 1986 |