ibudilast has been researched along with Leukodystrophy, Globoid Cell in 1 studies
Leukodystrophy, Globoid Cell: An autosomal recessive metabolic disorder caused by a deficiency of GALACTOSYLCERAMIDASE leading to intralysosomal accumulation of galactolipids such as GALACTOSYLCERAMIDES and PSYCHOSINE. It is characterized by demyelination associated with large multinucleated globoid cells, predominantly involving the white matter of the central nervous system. The loss of MYELIN disrupts normal conduction of nerve impulses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Krabbe disease (globoid cell leukodystrophy, GLD) is an inherited disease caused by a deficiency in the lysosomal enzyme galactocerebrosidase (GALC)." | 2.53 | Insights into the Pathogenesis and Treatment of Krabbe Disease. ( Bongarzone, ER; Escolar, ML; Gray, SJ; Kafri, T; Sands, MS; Vite, CH, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bongarzone, ER | 1 |
| Escolar, ML | 1 |
| Gray, SJ | 1 |
| Kafri, T | 1 |
| Vite, CH | 1 |
| Sands, MS | 1 |
1 review available for ibudilast and Leukodystrophy, Globoid Cell
| Article | Year |
|---|---|
Insights into the Pathogenesis and Treatment of Krabbe Disease.
Topics: Acetylcysteine; Animals; Antimetabolites; Bone Marrow Transplantation; Central Nervous System; Cyclo | 2016 |