ibudilast has been researched along with Brain Ischemia in 4 studies
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At 6 months after the start of ibudilast therapy, all patients reported the resolution of dizziness; of the 6 patients with depression at entry, all experienced significant improvement." | 7.74 | Effect of ibudilast on non-specific symptoms in patients with chronic cerebral ischemia. Analysis of cerebral blood flow. ( Harada, M; Inoue, N, 2008) |
| "At 6 months after the start of ibudilast therapy, all patients reported the resolution of dizziness; of the 6 patients with depression at entry, all experienced significant improvement." | 3.74 | Effect of ibudilast on non-specific symptoms in patients with chronic cerebral ischemia. Analysis of cerebral blood flow. ( Harada, M; Inoue, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, N | 2 |
| Harada, M | 2 |
| Fukuda, S | 1 |
| Inada, T | 1 |
| Sameshima, E | 1 |
| Tokushima, Y | 1 |
| Wakita, H | 1 |
| Tomimoto, H | 1 |
| Akiguchi, I | 1 |
| Lin, JX | 1 |
| Ihara, M | 1 |
| Ohtani, R | 1 |
| Shibata, M | 1 |
| Fukuyama, H | 1 |
| Kimura, J | 1 |
| Yamaguchi, S | 1 |
| Yamauchi, H | 1 |
| Ogawa, M | 1 |
| Doi, T | 1 |
| Yonekura, Y | 1 |
| Konishi, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center, Open-Label Biomarker Study to Evaluate MN-166 (Ibudilast) in Subjects With Amyotrophic Literal Sclerosis (ALS)[NCT02714036] | Phase 1/Phase 2 | 35 participants (Actual) | Interventional | 2016-05-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for ibudilast and Brain Ischemia
| Article | Year |
|---|---|
Effect of ibudilast on non-specific symptoms in patients with chronic cerebral ischemia. Analysis of cerebral blood flow.
Topics: Aged; Brain Ischemia; Cerebrovascular Circulation; Chronic Disease; Depression; Dizziness; Female; F | 2008 |
Effect of ibudilast on the reciprocal inhibitory visual-vestibular interaction closely related to dizziness after cerebral ischemia.
Topics: Acetazolamide; Aged; Aged, 80 and over; Brain Ischemia; Cerebrovascular Circulation; Depression; Diu | 2014 |
Ibudilast, a phosphodiesterase inhibitor, protects against white matter damage under chronic cerebral hypoperfusion in the rat.
Topics: Administration, Oral; Animals; Brain Ischemia; Chronic Disease; Dose-Response Relationship, Drug; Im | 2003 |
Pharmacological effects of ibudilast on cerebral circulation: a PET study.
Topics: Aged; Brain Ischemia; Cerebrovascular Circulation; Epoprostenol; Female; Humans; Male; Middle Aged; | 1993 |