ibudilast has been researched along with Brain Edema in 3 studies
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibudilast (IBD) is a non‑selective (3, 4, 10, 11) phosphodiesterase (PDE) inhibitor, used mainly as a bronchodilator for the treatment of bronchial asthma." | 6.55 | Ibudilast: a non‑selective phosphodiesterase inhibitor in brain disorders. ( Kurkowska-Jastrzębska, I; Mirowska-Guzel, D; Schwenkgrub, J; Zaremba, M, 2017) |
| "Ibudilast (IBD) is a non‑selective (3, 4, 10, 11) phosphodiesterase (PDE) inhibitor, used mainly as a bronchodilator for the treatment of bronchial asthma." | 2.55 | Ibudilast: a non‑selective phosphodiesterase inhibitor in brain disorders. ( Kurkowska-Jastrzębska, I; Mirowska-Guzel, D; Schwenkgrub, J; Zaremba, M, 2017) |
| "Experimental cerebral infarction accompanying altered cerebral energy metabolism and cerebral edema was produced in rats by injecting arachidonate into the left carotid artery." | 1.27 | [Effect of KC-404 on experimental cerebral infarction in rats]. ( Ichikawa, Y; Irikura, T; Kudo, Y; Nishino, K; Sugiura, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwenkgrub, J | 1 |
| Zaremba, M | 1 |
| Mirowska-Guzel, D | 1 |
| Kurkowska-Jastrzębska, I | 1 |
| Lee, JY | 1 |
| Cho, E | 1 |
| Ko, YE | 1 |
| Kim, I | 1 |
| Lee, KJ | 1 |
| Kwon, SU | 1 |
| Kang, DW | 1 |
| Kim, JS | 1 |
| Kudo, Y | 1 |
| Ichikawa, Y | 1 |
| Sugiura, H | 1 |
| Nishino, K | 1 |
| Irikura, T | 1 |
1 review available for ibudilast and Brain Edema
| Article | Year |
|---|---|
Ibudilast: a non‑selective phosphodiesterase inhibitor in brain disorders.
Topics: Animals; Brain Diseases; Brain Edema; Brain Infarction; Humans; Nervous System Diseases; Neurons; Ph | 2017 |
2 other studies available for ibudilast and Brain Edema
| Article | Year |
|---|---|
Ibudilast, a phosphodiesterase inhibitor with anti-inflammatory activity, protects against ischemic brain injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain Edema; Brain Infarction; Cell Death; Cytokines; | 2012 |
[Effect of KC-404 on experimental cerebral infarction in rats].
Topics: Animals; Brain; Brain Edema; Cerebral Infarction; Energy Metabolism; Male; Pyridines; Rats; Rats, In | 1985 |