ibudilast has been researched along with Asthma in 9 studies
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway hypersensitivity to histamine inhalation." | 9.07 | Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Osaki, R; Yano, S, 1992) |
| "This study is to investigate the effect of ibudilast on apoptosis of airway eosinophil in asthmatic guinea pigs and its mechanism." | 7.75 | [Effect of ibudilast on apoptosis of airway eosinophil in asthmatic guinea pigs]. ( Lü, WH; Xu, S; Zhang, HQ, 2009) |
| "Ibudilast, a unique agent with vasodilating and antiallergic actions, was studied in 13 asthmatics for its effect on airway hypersensitivity to histamine inhalation." | 5.07 | Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma. ( Hoshino, K; Kawasaki, A; Mizushima, Y; Osaki, R; Yano, S, 1992) |
| "This study is to investigate the effect of ibudilast on apoptosis of airway eosinophil in asthmatic guinea pigs and its mechanism." | 3.75 | [Effect of ibudilast on apoptosis of airway eosinophil in asthmatic guinea pigs]. ( Lü, WH; Xu, S; Zhang, HQ, 2009) |
| "In the present study, we examined the effect of ibudilast (KC-404), a novel anti-asthma agent, on beta2 integrin expression induced by PAF." | 3.70 | Inhibitory effect of ibudilast (KC-404) on the expression of the beta2 integrin family on an eosinophilic cell line (EoL-1). ( Chihara, J; Hayashi, N; Honda, K; Kayaba, H; Kurachi, D; Saito, N; Urayama, O; Yamamoto, T, 1998) |
| "The effect of antiallergic agents (DSCG) (disodium cromoglycate, ketotifen, and ibudilast) and beclomethasone dipropionate inhaler (BDI) on bronchial hyperresponsiveness to histamine inhalation was retrospectively assessed in 72 asthmatic patients with more than a year's duration of the disease." | 3.68 | Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study. ( Hoshino, K; Kawasaki, A; Kobayashi, M; Mizushima, Y; Oosaki, R; Yano, S, 1993) |
| "In this study, we investigated the pharmacological reactions induced by ibudilast to the complement system with the aim of clarifying the functional relation of the complement system to allergic reactions and pathology in patients with bronchial asthma." | 3.68 | [Complement fragments in patients with bronchial asthma]. ( Deguchi, M; Doi, T; Fukuda, W; Kasamatsu, Y; Okamoto, M; Onodera, H; Takemura, S; Tanaka, M; Ueda, M; Yanagida, K, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kodimuthali, A | 1 |
| Jabaris, SS | 1 |
| Pal, M | 1 |
| Xu, S | 1 |
| Lü, WH | 1 |
| Zhang, HQ | 1 |
| Nagai, H | 1 |
| Iwamoto, T | 1 |
| Nishiyori, T | 1 |
| Takizawa, T | 1 |
| Tsuchiya, H | 1 |
| Koda, A | 1 |
| Ohashi, M | 1 |
| Uno, T | 1 |
| Nishino, K | 1 |
| Hoshino, K | 2 |
| Kawasaki, A | 2 |
| Mizushima, Y | 2 |
| Oosaki, R | 1 |
| Yano, S | 2 |
| Kobayashi, M | 1 |
| Chihara, J | 1 |
| Urayama, O | 1 |
| Kayaba, H | 1 |
| Honda, K | 1 |
| Saito, N | 1 |
| Hayashi, N | 1 |
| Kurachi, D | 1 |
| Yamamoto, T | 1 |
| Tamaoki, J | 1 |
| Isono, K | 1 |
| Sakai, N | 1 |
| Chiyotani, A | 1 |
| Konno, K | 1 |
| Osaki, R | 1 |
| Onodera, H | 1 |
| Okamoto, M | 1 |
| Takemura, S | 1 |
| Doi, T | 1 |
| Kasamatsu, Y | 1 |
| Yanagida, K | 1 |
| Fukuda, W | 1 |
| Tanaka, M | 1 |
| Deguchi, M | 1 |
| Ueda, M | 1 |
1 review available for ibudilast and Asthma
| Article | Year |
|---|---|
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Topics: Asthma; Humans; Phosphodiesterase 4 Inhibitors; Phosphodiesterase Inhibitors; Pulmonary Disease, Chr | 2008 |
1 trial available for ibudilast and Asthma
| Article | Year |
|---|---|
Effect of ibudilast: a novel antiasthmatic agent, on airway hypersensitivity in bronchial asthma.
Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Cromolyn Sodium; Female; Hist | 1992 |
7 other studies available for ibudilast and Asthma
| Article | Year |
|---|---|
[Effect of ibudilast on apoptosis of airway eosinophil in asthmatic guinea pigs].
Topics: Animals; Anti-Asthmatic Agents; Apoptosis; Asthma; Bronchoalveolar Lavage Fluid; Eosinophils; fas Re | 2009 |
Pharmacological studies on newly synthesized anti-allergic agents, 2-methyl-3-piperidino-beta-propionaphtone hydrochloride (KZ-111) and 3-isobutyryl-2-isopropylpyrazole-[1, 5-a] pyridine (KC-404).
Topics: Animals; Asthma; Chromones; Guinea Pigs; Histamine H1 Antagonists; Histamine Release; Hypersensitivi | 1983 |
Effect of ibudilast, a novel antiasthmatic agent, on anaphylactic bronchoconstriction: predominant involvement of endogenous slow reacting substance of anaphylaxis.
Topics: Acetylcholine; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Asthma; Bronchoconstriction; Bronc | 1993 |
Comparison of the effects on bronchial hyperresponsiveness of antiallergic agents and beclomethasone dipropionate in long-term bronchial asthma. A retrospective study.
Topics: Adolescent; Adult; Aged; Asthma; Beclomethasone; Bronchial Hyperreactivity; Bronchial Provocation Te | 1993 |
Inhibitory effect of ibudilast (KC-404) on the expression of the beta2 integrin family on an eosinophilic cell line (EoL-1).
Topics: Asthma; Bronchodilator Agents; CD18 Antigens; Humans; Integrins; Lymphocyte Function-Associated Anti | 1998 |
The anti-asthmatic agent KC 404 inhibits sodium absorption by canine tracheal epithelium.
Topics: Absorption; Amiloride; Animals; Asthma; Biological Transport, Active; Dogs; Electrochemistry; Epithe | 1992 |
[Complement fragments in patients with bronchial asthma].
Topics: Adult; Aged; Anaphylatoxins; Asthma; Bronchi; Complement Hemolytic Activity Assay; Complement System | 1991 |