ibudilast has been researched along with Alzheimer Disease in 1 studies
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibudilast is a multi-target drug, as it is a phosphodiesterase inhibitor and toll-like receptor 4 (TLR4) antagonist." | 5.91 | Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation. ( Chaudry, O; Figueiredo-Pereira, ME; Liu, Q; Oliveros, G; Qiu, Y; Rockwell, P; Serrano, PA; Wallace, CH; Xie, L, 2023) |
| "Ibudilast is a multi-target drug, as it is a phosphodiesterase inhibitor and toll-like receptor 4 (TLR4) antagonist." | 1.91 | Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation. ( Chaudry, O; Figueiredo-Pereira, ME; Liu, Q; Oliveros, G; Qiu, Y; Rockwell, P; Serrano, PA; Wallace, CH; Xie, L, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oliveros, G | 1 |
| Wallace, CH | 1 |
| Chaudry, O | 1 |
| Liu, Q | 1 |
| Qiu, Y | 1 |
| Xie, L | 1 |
| Rockwell, P | 1 |
| Figueiredo-Pereira, ME | 1 |
| Serrano, PA | 1 |
1 other study available for ibudilast and Alzheimer Disease
| Article | Year |
|---|---|
Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Drug Repositioning; Femal | 2023 |