Page last updated: 2024-10-28

ibudilast and Alcohol Drinking

ibudilast has been researched along with Alcohol Drinking in 5 studies

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
" In this study, we examined the ability of ibudilast, a non-selective phosphodiesterase inhibitor, to reduce alcohol drinking and relapse in alcohol-preferring P rats, high-alcohol drinking HAD1 rats, and in mice made dependent on alcohol through cycles of alcohol vapor exposure."7.81Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence. ( Becker, HC; Bell, RL; Cui, C; Egli, M; Franklin, KM; Johnson, KW; Lopez, MF, 2015)
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."7.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)
" In this study, we examined the ability of ibudilast, a non-selective phosphodiesterase inhibitor, to reduce alcohol drinking and relapse in alcohol-preferring P rats, high-alcohol drinking HAD1 rats, and in mice made dependent on alcohol through cycles of alcohol vapor exposure."3.81Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence. ( Becker, HC; Bell, RL; Cui, C; Egli, M; Franklin, KM; Johnson, KW; Lopez, MF, 2015)
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."3.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's4 (80.00)2.80

Authors

AuthorsStudies
Grodin, EN4
Nieto, SJ1
Meredith, LR2
Burnette, E2
O'Neill, J1
Alger, J1
London, ED1
Miotto, K3
Evans, CJ1
Irwin, MR2
Ray, LA4
Green, R1
Chorpita, M1
Burnette, EM1
Baskerville, WA1
Bujarski, S1
Towns, B1
Nieto, S1
Lim, A1
Lin, J1
Gillis, A1
Evans, C1
Bell, RL1
Lopez, MF1
Cui, C1
Egli, M1
Johnson, KW1
Franklin, KM1
Becker, HC1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Development of Ibudilast as a Novel Treatment for Alcohol Dependence[NCT02025998]Phase 124 participants (Actual)Interventional2013-12-31Completed
A Randomized Controlled Clinical Trial of the Neuroimmune Modulator Ibudilast for the Treatment of Alcohol Use Disorder[NCT03594435]Phase 2102 participants (Actual)Interventional2018-10-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for ibudilast and Alcohol Drinking

ArticleYear
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial.
    Addiction biology, 2022, Volume: 27, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; C-Reactive Protein; Choline; Creatine; Humans;

2022
Ibudilast moderates the effect of mood on alcohol craving during stress exposure.
    Experimental and clinical psychopharmacology, 2022, Volume: 30, Issue:5

    Topics: Affect; Alcohol Drinking; Alcoholism; Craving; Ethanol; Humans; Indolizines; Pyrazoles; Pyridines

2022
Ibudilast for alcohol use disorder: study protocol for a phase II randomized clinical trial.
    Trials, 2020, Sep-11, Volume: 21, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Clinical Trials, Phase II as Topic; Craving; Double-Blind Method; Fema

2020
Ibudilast, a neuroimmune modulator, reduces heavy drinking and alcohol cue-elicited neural activation: a randomized trial.
    Translational psychiatry, 2021, 06-12, Volume: 11, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Craving; Cues; Humans; Magnetic Resonance Imaging; Pyridines

2021

Other Studies

1 other study available for ibudilast and Alcohol Drinking

ArticleYear
Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.
    Addiction biology, 2015, Volume: 20, Issue:1

    Topics: Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Disease Models, Animal; Male; Mice; Phospho

2015