ibotenic acid has been researched along with Disease Models, Animal in 160 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present work we analyzed the effect of the chronic administration of risperidone (2mg/kg over 65 days) on behavioural, morphological and molecular aspects in an experimental model of schizophrenia obtained by bilateral injection of ibotenic acid into the ventral hippocampus of new-born rats." | 7.79 | Chronic administration of risperidone in a rat model of schizophrenia: a behavioural, morphological and molecular study. ( Arji, M; Carro, J; Castellano, O; de Anchieta de Castro E Horta, J; Gómez-Nieto, R; Herrero-Turrión, MJ; López, DE; Molina, V; Riolobos, AS; Sancho, C, 2013) |
| "Clozapine is an effective atypical antipsychotic drug used to treat schizophrenia." | 7.73 | Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia. ( Christopher, NC; Levin, ED, 2006) |
| "The lesions induced by Ibotenic acid (IA) emulate some of the symptoms associated with schizophrenia, such as impaired working memory that is predominantly organized by the medial prefrontal cortex (mPFC), or difficulties in social interactions that aremainly organized by the amygdala (AMG)." | 4.02 | Ibotenic acid induced lesions impair the modulation of dendritic spine plasticity in the prefrontal cortex and amygdala, a phenomenon that underlies working memory and social behavior. ( Flores-Soto, M; González-Burgos, I; Martín-Amaya-Barajas, FL; Martínez-Torres, NI; Vázquez-Hernández, N, 2021) |
| " Intraperitoneal pentylenetetrazole injection did not induce any seizure activity in the control rats, although it elicited seizures of variable severity in the polymicrogyria rats." | 3.81 | Increased expression of GAP43 in interneurons in a rat model of experimental polymicrogyria. ( Matsui, K; Takano, T, 2015) |
| "In the present work we analyzed the effect of the chronic administration of risperidone (2mg/kg over 65 days) on behavioural, morphological and molecular aspects in an experimental model of schizophrenia obtained by bilateral injection of ibotenic acid into the ventral hippocampus of new-born rats." | 3.79 | Chronic administration of risperidone in a rat model of schizophrenia: a behavioural, morphological and molecular study. ( Arji, M; Carro, J; Castellano, O; de Anchieta de Castro E Horta, J; Gómez-Nieto, R; Herrero-Turrión, MJ; López, DE; Molina, V; Riolobos, AS; Sancho, C, 2013) |
| "Ibotenic acid injected intracerebrally over a broad dose range to 5-day-old mice induces cystic white matter (WM) lesions that mimic periventricular leukomalacia (PVL) of preterm infants." | 3.74 | Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: interaction with plasmin inhibitors and anti-inflammatory drugs. ( Carmeliet, P; Hennebert, O; Laudenbach, V; Legros, H; Leroux, P; Marret, S, 2007) |
| "Clozapine is an effective atypical antipsychotic drug used to treat schizophrenia." | 3.73 | Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia. ( Christopher, NC; Levin, ED, 2006) |
| "The neonatal (PND 7) lesion of the ventral hippocampus (VH) with ibotenic acid represents a well-established experimental paradigm that recapitulates many schizophrenia-like phenomena." | 3.71 | Developmental and stress-related changes of neurotrophic factor gene expression in an animal model of schizophrenia. ( Lipska, BK; Molteni, R; Racagni, G; Riva, MA; Weinberger, DR, 2001) |
| "Postnatal lesion with ibotenic acid in the ventral hippocampus produces several behavioural effects that resemble the symptoms of schizophrenia." | 3.70 | Social memory is impaired in neonatally ibotenic acid lesioned rats. ( Becker, A; Grecksch, G, 2000) |
| "Rats were trained for 20 days in a modified T maze to perform an invariant, tactile discrimination and a variable, delayed spatial discrimination, and then were exposed either to 30 min of transient forebrain ischemia or to low- or high-dose ibotenic acid to damage the dorsal hippocampus bilaterally." | 3.68 | Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions. ( Davis, HP; Dunlap, WP; Towle, A; Volpe, BT, 1992) |
| "Bilateral ibotenic acid lesions of the anteromedial neostriatum produce neuropathological and behavioral changes in rats that are characterized by locomotor hyperactivity and severe maze learning impairments, which can be viewed as analogous to changes seen in Huntington disease." | 3.67 | Graft-induced behavioral recovery in an animal model of Huntington disease. ( Björklund, A; Dunnett, SB; Isacson, O, 1986) |
| "Animal models of Alzheimer's Disease (AD) are designed to duplicate a subset of selected neuropathological, biochemical and behavioral changes that are associated with AD." | 2.38 | A primate model of Alzheimer's disease. ( Wenk, GL, 1993) |
| "Schizophrenia is conceptualized as a neurodevelopmental disorder in which developmental alterations in immature brain systems are not clear." | 1.43 | Neonatal ventral hippocampus lesion changes nuclear restricted protein/brain (NRP/B) expression in hippocampus, cortex and striatum in developmental periods of rats. ( Chen, X; Dai, Z; Lei, Y; Ling, S; Lui, F; Tian, Y; Yang, J; Zhang, J; Zhang, Z, 2016) |
| "Besides chronic stress, chronic pain is a prevalent determinant for depression." | 1.42 | The anterior cingulate cortex is a critical hub for pain-induced depression. ( Barrot, M; Barthas, F; Hugel, S; Sellmeijer, J; Waltisperger, E; Yalcin, I, 2015) |
| "The spatial learning and memory of Alzheimer's disease (AD) rats in STL-bFGF-NP group were significantly improved compared with AD model group, and were also better than other preparations." | 1.40 | Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease. ( Chen, J; Feng, C; Jiang, X; Liu, Q; Pang, Z; Shao, X; Zhang, C; Zhang, Q, 2014) |
| "The progressive development of Alzheimer's disease (AD) pathology follows a spatiotemporal pattern in the human brain." | 1.40 | Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease. ( Brundin, P; George, S; Gouras, GK; Graff, C; Grueninger, F; Petit, GH; Rönnbäck, A; Winblad, B, 2014) |
| "For the in vivo study, an Alzheimer's disease (AD) model with severe damage to the hippocampal tissue was constructed by injecting the hippocampi of rats with aggregated Aβ1-40, followed 48 h later by an injection of ibotenate [an agonist for N-methyl-d-aspartate (NMDA) receptor]." | 1.40 | SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids. ( Inoue, T; Murayama, N; Narii, N; Noshita, T; Ogino, R; Oka, T; Takemoto, N; Toba, T; Ueno, N; Yoshida, S, 2014) |
| "Valproic acid (VPA) has been used for many years as a drug of choice for epilepsy and mood disorders." | 1.35 | Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity. ( Brignani, S; Contestabile, A; Eleuteri, S; Monti, B, 2009) |
| "Perinatal brain injuries often result in irreversible learning disabilities, which manifest in early childhood." | 1.33 | Treatment-induced prevention of learning deficits in newborn mice with brain lesions. ( Bouslama, M; Chauvière, L; Fontaine, RH; Gallego, J; Gressens, P; Matrot, B, 2006) |
| "Ibotenic acid was injected bilaterally into MDTN in rats." | 1.32 | Effects of a mediodorsal thalamus lesion on prefrontal inhibitory circuitry: implications for schizophrenia. ( Lewis, DA; Volk, DW, 2003) |
| "Periventricular leukomalacia is one of the main causes of cerebral palsy." | 1.31 | Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge. ( Bac, P; Evrard, P; Gressens, P; Husson, I; Mesplès, B; Vamecq, J, 2002) |
| "Memory deficits as the first symptom of Alzheimer's disease can be explained by the initial lesion of the entorhinal-hippocampal connection." | 1.29 | Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts. ( Kraemer, M; Qü, M; Schleicher, A; Schroeter, M; Witte, OW; Zilles, K, 1995) |
| "Ibotenic acid was injected into the nucleus basalis magnocellularis region of rat brain in order to study whether an elevation of lipase activities was associated with the degeneration of cholinergic neurons in this potential animal model of Alzheimer's disease." | 1.28 | Stimulation of mono- and diacylglycerol lipase activities in ibotenate-induced lesions of nucleus basalis magnocellularis. ( Farooqui, AA; Horrocks, LA; Wallace, LJ, 1991) |
| "The apomorphine test was highly reproducible and individual animals responded with a similar set and incidence of dyskinesia in successive tests." | 1.28 | A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon. ( Hantraye, P; Isacson, O; Maziere, M; Riche, D, 1990) |
| "Although it is known that Parkinson's disease results from a loss of dopaminergic neurons in the substantia nigra, the resulting alterations in activity in the basal ganglia responsible for parkinsonian motor deficits are still poorly characterized." | 1.28 | Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. ( Bergman, H; DeLong, MR; Wichmann, T, 1990) |
| "Pentobarbital treatment reduced 2-DG accumulation in all brain areas examined and these reductions were not influenced by the nBM lesions." | 1.27 | Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis. ( Fibiger, HC; Lamarca, MV, 1984) |
| "Huntington's disease is accompanied by severe neuronal death in the striatum, but despite this cell loss, there is a marked increase in the striatal concentration of somatostatin-like immunoreactivity (SLI)." | 1.27 | Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease. ( Beal, MF; Burd, GD; Landis, DM; Marshall, PE; Martin, JB, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (5.63) | 18.7374 |
| 1990's | 21 (13.13) | 18.2507 |
| 2000's | 68 (42.50) | 29.6817 |
| 2010's | 57 (35.63) | 24.3611 |
| 2020's | 5 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Yang, X | 1 |
| Ji, J | 1 |
| Liu, C | 1 |
| Zhou, M | 1 |
| Li, H | 1 |
| Ye, S | 1 |
| Hu, Q | 1 |
| Doulah, A | 1 |
| Mahmoodi, G | 1 |
| Pourmahdi Borujeni, M | 1 |
| Martínez-Torres, NI | 1 |
| Vázquez-Hernández, N | 1 |
| Martín-Amaya-Barajas, FL | 1 |
| Flores-Soto, M | 1 |
| González-Burgos, I | 1 |
| Lee, YA | 1 |
| Kim, YJ | 1 |
| Lee, JS | 1 |
| Lee, S | 1 |
| Goto, Y | 2 |
| Magdaleno-Madrigal, VM | 1 |
| Contreras-Murillo, G | 1 |
| Camacho-Abrego, I | 1 |
| Negrete-Díaz, JV | 1 |
| Valdés-Cruz, A | 1 |
| Fernández-Mas, R | 1 |
| Almazán-Alvarado, S | 1 |
| Flores, G | 1 |
| Daher, I | 1 |
| Le Dieu-Lugon, B | 1 |
| Dourmap, N | 1 |
| Lecuyer, M | 1 |
| Ramet, L | 1 |
| Gomila, C | 1 |
| Ausseil, J | 1 |
| Marret, S | 6 |
| Leroux, P | 5 |
| Roy, V | 1 |
| El Mestikawy, S | 1 |
| Daumas, S | 1 |
| Gonzalez, B | 1 |
| Leroux-Nicollet, I | 1 |
| Cleren, C | 1 |
| Tripathi, SJ | 1 |
| Chakraborty, S | 1 |
| Srikumar, BN | 1 |
| Raju, TR | 1 |
| Shankaranarayana Rao, BS | 1 |
| Descloux, C | 1 |
| Ginet, V | 1 |
| Rummel, C | 1 |
| Truttmann, AC | 1 |
| Puyal, J | 1 |
| Gong, JL | 1 |
| Lou, XT | 1 |
| Yuan, YX | 1 |
| Chen, LW | 1 |
| Ji, PT | 1 |
| Li, L | 1 |
| Zhao, Y | 1 |
| Zhang, H | 1 |
| Zhang, J | 2 |
| Li, P | 1 |
| Wang, Y | 2 |
| Liu, J | 1 |
| Zhang, Z | 2 |
| Cheng, W | 1 |
| Degos, V | 1 |
| Peineau, S | 1 |
| Nijboer, C | 1 |
| Kaindl, AM | 1 |
| Sigaut, S | 1 |
| Favrais, G | 2 |
| Plaisant, F | 2 |
| Teissier, N | 1 |
| Gouadon, E | 1 |
| Lombet, A | 1 |
| Saliba, E | 1 |
| Collingridge, GL | 1 |
| Maze, M | 1 |
| Nicoletti, F | 1 |
| Heijnen, C | 1 |
| Mantz, J | 1 |
| Kavelaars, A | 1 |
| Gressens, P | 20 |
| da Silva, GS | 1 |
| Giusti, H | 1 |
| Castro, OW | 1 |
| Garcia-Cairasco, N | 1 |
| Gargaglioni, LH | 3 |
| Branco, LG | 2 |
| Glass, ML | 1 |
| Nobs, L | 1 |
| Nestel, S | 1 |
| Kulik, A | 1 |
| Nitsch, C | 1 |
| Atanasoski, S | 1 |
| Placek, K | 1 |
| Dippel, WC | 1 |
| Jones, S | 1 |
| Brady, AM | 1 |
| Hosseini, N | 2 |
| Alaei, H | 2 |
| Reisi, P | 2 |
| Radahmadi, M | 2 |
| Zhang, C | 2 |
| Chen, J | 2 |
| Feng, C | 2 |
| Shao, X | 2 |
| Liu, Q | 2 |
| Zhang, Q | 2 |
| Pang, Z | 1 |
| Jiang, X | 2 |
| Hong, SW | 1 |
| Heo, H | 1 |
| Yang, JH | 1 |
| Han, M | 1 |
| Kim, DH | 1 |
| Kwon, YK | 1 |
| George, S | 1 |
| Rönnbäck, A | 1 |
| Gouras, GK | 1 |
| Petit, GH | 1 |
| Grueninger, F | 1 |
| Winblad, B | 1 |
| Graff, C | 1 |
| Brundin, P | 3 |
| Ikeda, H | 1 |
| Takasu, S | 1 |
| Murase, K | 1 |
| Lopes, LT | 1 |
| Biancardi, V | 1 |
| Vieira, EB | 1 |
| Leite-Panissi, C | 1 |
| Bícego, KC | 1 |
| Marei, HE | 1 |
| Farag, A | 1 |
| Althani, A | 1 |
| Afifi, N | 1 |
| Abd-Elmaksoud, A | 1 |
| Lashen, S | 1 |
| Rezk, S | 1 |
| Pallini, R | 1 |
| Casalbore, P | 1 |
| Cenciarelli, C | 1 |
| Takano, T | 3 |
| Matsui, K | 1 |
| Wegleiter, K | 1 |
| Hermann, M | 1 |
| Posod, A | 1 |
| Wechselberger, K | 1 |
| Stanika, RI | 1 |
| Obermair, GJ | 1 |
| Kiechl-Kohlendorfer, U | 1 |
| Urbanek, M | 4 |
| Griesmaier, E | 4 |
| Ogino, R | 1 |
| Murayama, N | 2 |
| Noshita, T | 2 |
| Takemoto, N | 1 |
| Toba, T | 1 |
| Oka, T | 1 |
| Narii, N | 1 |
| Yoshida, S | 1 |
| Ueno, N | 1 |
| Inoue, T | 1 |
| Cabungcal, JH | 1 |
| Counotte, DS | 1 |
| Lewis, E | 1 |
| Tejeda, HA | 1 |
| Piantadosi, P | 1 |
| Pollock, C | 1 |
| Calhoon, GG | 1 |
| Sullivan, E | 1 |
| Presgraves, E | 1 |
| Kil, J | 1 |
| Hong, LE | 1 |
| Cuenod, M | 1 |
| Do, KQ | 1 |
| O'Donnell, P | 2 |
| Bataveljic, D | 1 |
| Petrovic, J | 1 |
| Lazic, K | 1 |
| Saponjic, J | 1 |
| Andjus, P | 1 |
| Arunsundar, M | 1 |
| Shanmugarajan, TS | 1 |
| Ravichandran, V | 1 |
| Barthas, F | 1 |
| Sellmeijer, J | 1 |
| Hugel, S | 1 |
| Waltisperger, E | 1 |
| Barrot, M | 1 |
| Yalcin, I | 1 |
| Hou, XQ | 1 |
| Zhang, L | 1 |
| Yang, C | 1 |
| Rong, CP | 1 |
| He, WQ | 1 |
| Zhang, CX | 1 |
| Li, S | 1 |
| Su, RY | 1 |
| Chang, X | 1 |
| Qin, JH | 1 |
| Chen, YB | 1 |
| Xian, SX | 1 |
| Wang, Q | 1 |
| Grigson, PS | 1 |
| Colechio, EM | 1 |
| Power, ML | 1 |
| Schulkin, J | 1 |
| Norgren, R | 1 |
| Thomsen, MS | 1 |
| Andersen, MV | 1 |
| Christoffersen, PR | 1 |
| Jensen, MD | 1 |
| Lichota, J | 1 |
| Moos, T | 1 |
| Gut, NK | 1 |
| Winn, P | 1 |
| Busse, S | 1 |
| Schwarting, RK | 1 |
| Montgomery, KS | 1 |
| Edwards, G | 1 |
| Levites, Y | 1 |
| Kumar, A | 2 |
| Myers, CE | 1 |
| Gluck, MA | 1 |
| Setlow, B | 1 |
| Bizon, JL | 1 |
| Guirado, R | 1 |
| Umemori, J | 1 |
| Sipilä, P | 1 |
| Castrén, E | 1 |
| Tian, Y | 1 |
| Yang, J | 2 |
| Lei, Y | 1 |
| Dai, Z | 1 |
| Chen, X | 1 |
| Lui, F | 1 |
| Ling, S | 1 |
| Pansiot, J | 1 |
| Pham, H | 1 |
| Dalous, J | 1 |
| Chevenne, D | 1 |
| Colella, M | 1 |
| Schwendimann, L | 4 |
| Fafouri, A | 1 |
| Mairesse, J | 1 |
| Moretti, R | 1 |
| Schang, AL | 1 |
| Charriaut-Marlangue, C | 2 |
| Baud, O | 2 |
| Lukacova, K | 1 |
| Pavukova, E | 1 |
| Kostal, L | 1 |
| Bilcik, B | 1 |
| Kubikova, L | 1 |
| Neymotin, SA | 1 |
| Talbot, ZN | 1 |
| Jung, JQ | 1 |
| Fenton, AA | 2 |
| Lytton, WW | 1 |
| Bliss-Moreau, E | 1 |
| Moadab, G | 1 |
| Santistevan, A | 1 |
| Amaral, DG | 1 |
| Scorza, FA | 1 |
| Arida, RM | 1 |
| Cavalheiro, EA | 1 |
| Ji, C | 1 |
| Li, Q | 1 |
| Aisa, H | 1 |
| Yang, N | 1 |
| Dong, YL | 1 |
| Liu, YY | 1 |
| Wang, T | 1 |
| Hao, Q | 1 |
| Zhu, HB | 1 |
| Zuo, PP | 1 |
| Sawai, C | 1 |
| Takeuchi, Y | 1 |
| Eleuteri, S | 1 |
| Monti, B | 1 |
| Brignani, S | 1 |
| Contestabile, A | 1 |
| Mazurová, Y | 1 |
| Osterreicher, J | 1 |
| Valousková, V | 1 |
| Kadish, I | 1 |
| van Groen, T | 1 |
| Wang, X | 2 |
| Stewart, L | 1 |
| Cortez, MA | 1 |
| Wu, Y | 2 |
| Velazquez, JL | 1 |
| Liu, CC | 1 |
| Shen, L | 1 |
| Snead, OC | 1 |
| Alexander, KS | 1 |
| Brooks, JM | 1 |
| Sarter, M | 1 |
| Bruno, JP | 1 |
| Hamani, C | 1 |
| Diwan, M | 1 |
| Macedo, CE | 1 |
| Brandão, ML | 1 |
| Shumake, J | 1 |
| Gonzalez-Lima, F | 1 |
| Raymond, R | 1 |
| Lozano, AM | 1 |
| Fletcher, PJ | 1 |
| Nobrega, JN | 1 |
| Wolf, R | 1 |
| Matzke, K | 1 |
| Paelchen, K | 1 |
| Dobrowolny, H | 1 |
| Bogerts, B | 2 |
| Schwegler, H | 1 |
| Bonis, JM | 1 |
| Neumueller, SE | 1 |
| Krause, KL | 1 |
| Kiner, T | 1 |
| Smith, A | 1 |
| Marshall, BD | 1 |
| Qian, B | 1 |
| Pan, LG | 1 |
| Forster, HV | 1 |
| Hennebert, C | 1 |
| Catteau, J | 1 |
| Legros, H | 2 |
| Hennebert, O | 3 |
| Laudenbach, V | 2 |
| Zhao, Z | 1 |
| Zhao, S | 1 |
| Xu, N | 1 |
| Yu, C | 1 |
| Guan, S | 1 |
| Liu, X | 1 |
| Huang, L | 1 |
| Liao, W | 1 |
| Jia, W | 1 |
| Malek, M | 1 |
| Zahedi Asl, S | 1 |
| Sarkaki, A | 1 |
| Farbood, Y | 1 |
| Doulah, AH | 1 |
| Alison, M | 1 |
| Azoulay, R | 1 |
| Chalard, F | 1 |
| Sebag, G | 1 |
| Lupinsky, D | 1 |
| Moquin, L | 1 |
| Gratton, A | 1 |
| Chen, A | 2 |
| Siow, B | 1 |
| Blamire, AM | 1 |
| Lako, M | 1 |
| Clowry, GJ | 3 |
| Sokolowska, P | 1 |
| Passemard, S | 1 |
| Mok, A | 1 |
| Gozes, I | 1 |
| Drouin-Ouellet, J | 1 |
| Brownell, AL | 1 |
| Saint-Pierre, M | 1 |
| Fasano, C | 1 |
| Emond, V | 1 |
| Trudeau, LE | 1 |
| Lévesque, D | 1 |
| Cicchetti, F | 1 |
| Ahmed, T | 1 |
| Gilani, AH | 1 |
| Carlsson, Y | 1 |
| Vontell, R | 1 |
| Rousset, CI | 1 |
| Lebon, S | 1 |
| Supramaniam, V | 1 |
| Hagberg, H | 1 |
| Jacotot, E | 1 |
| Maior, RS | 1 |
| Hori, E | 1 |
| Barros, M | 1 |
| Teixeira, DS | 1 |
| Tavares, MC | 1 |
| Ono, T | 1 |
| Nishijo, H | 1 |
| Tomaz, C | 1 |
| Qian, Y | 1 |
| Feng, L | 1 |
| Zha, Y | 1 |
| Yu, X | 1 |
| Wang, LN | 1 |
| Ma, L | 1 |
| You, R | 1 |
| Cui, R | 1 |
| Ji, D | 1 |
| Zhang, CF | 1 |
| Yang, ZL | 1 |
| Ji, H | 1 |
| Cai, L | 1 |
| Bakalli, H | 1 |
| Rinaman, L | 1 |
| Lee, H | 1 |
| Dvorak, D | 1 |
| Kao, HY | 1 |
| Duffy, ÁM | 1 |
| Scharfman, HE | 1 |
| Castellano, O | 1 |
| Arji, M | 1 |
| Sancho, C | 1 |
| Carro, J | 1 |
| Riolobos, AS | 1 |
| Molina, V | 1 |
| Gómez-Nieto, R | 1 |
| de Anchieta de Castro E Horta, J | 1 |
| Herrero-Turrión, MJ | 1 |
| López, DE | 1 |
| Pace, JR | 1 |
| Lonser, RR | 1 |
| Kirkby, RD | 1 |
| Jeffries, N | 1 |
| Rogawski, MA | 1 |
| Oldfield, EH | 1 |
| Arquié, C | 1 |
| Bodenant, C | 1 |
| Laquerrière, A | 2 |
| Marpeau, L | 1 |
| Luo, J | 1 |
| Kaplitt, MG | 1 |
| Fitzsimons, HL | 1 |
| Zuzga, DS | 1 |
| Liu, Y | 1 |
| Oshinsky, ML | 1 |
| During, MJ | 1 |
| Volk, DW | 1 |
| Lewis, DA | 1 |
| Gibson, CL | 1 |
| Van den Buuse, M | 1 |
| Garner, B | 1 |
| Koch, M | 3 |
| Vamecq, J | 2 |
| Maurois, P | 1 |
| Bac, P | 2 |
| Bailly, F | 1 |
| Bernier, JL | 1 |
| Stables, JP | 1 |
| Husson, I | 2 |
| Need, AC | 1 |
| Irvine, EE | 1 |
| Giese, KP | 1 |
| Dommergues, MA | 2 |
| Verney, C | 1 |
| Carmeliet, P | 2 |
| Ishida, K | 1 |
| Shimizu, H | 1 |
| Hida, H | 1 |
| Urakawa, S | 1 |
| Ida, K | 1 |
| Nishino, H | 1 |
| Ahmed, MM | 1 |
| Hoshino, H | 1 |
| Chikuma, T | 1 |
| Yamada, M | 1 |
| Kato, T | 1 |
| Schmadel, S | 1 |
| Schwabe, K | 2 |
| Li, Y | 1 |
| Qin, HQ | 1 |
| Chen, QS | 1 |
| Wang, JJ | 1 |
| Zhong, Z | 1 |
| Qu, Z | 1 |
| Wang, N | 1 |
| Wang, J | 1 |
| Xie, Z | 1 |
| Zhang, F | 1 |
| Zhang, W | 1 |
| Lu, Z | 1 |
| Sfaello, I | 1 |
| Arzimanoglou, A | 1 |
| Hu, Y | 1 |
| Xia, Z | 1 |
| Sun, Q | 1 |
| Orsi, A | 1 |
| Rees, D | 1 |
| Levin, ED | 2 |
| Christopher, NC | 1 |
| Belcher, AM | 1 |
| Harrington, RA | 1 |
| Malkova, L | 1 |
| Mishkin, M | 1 |
| Marquis, JP | 1 |
| Goulet, S | 1 |
| Doré, FY | 1 |
| Otsuka, Y | 1 |
| Watanabe, S | 1 |
| Bouslama, M | 2 |
| Chauvière, L | 1 |
| Fontaine, RH | 2 |
| Matrot, B | 2 |
| Gallego, J | 2 |
| Kang, M | 1 |
| Kim, JH | 1 |
| Cho, C | 1 |
| Lee, KY | 1 |
| Shin, M | 1 |
| Hong, M | 1 |
| Shim, I | 1 |
| Bae, H | 1 |
| Nakamura, S | 1 |
| Katsuragi, R | 1 |
| Ohno, T | 1 |
| Keller, M | 3 |
| Gorna, A | 1 |
| Sarkozy, G | 3 |
| Simbruner, G | 3 |
| Lelièvre, V | 1 |
| Gonzalez, D | 1 |
| Miyamoto, O | 1 |
| Touge, T | 1 |
| Sumitani, K | 1 |
| Kuriyama, S | 1 |
| Itano, T | 1 |
| He, X | 1 |
| Kapelari, K | 1 |
| Naylor, MC | 1 |
| Negia, M | 1 |
| Noetzel, M | 1 |
| Burns, TC | 1 |
| Demorest, ZL | 1 |
| Low, WC | 1 |
| Ahnaou, A | 1 |
| Nayak, S | 1 |
| Heylen, A | 1 |
| Ashton, D | 1 |
| Drinkenburg, WH | 1 |
| Hruska, Z | 1 |
| Dohanich, GP | 1 |
| Dias, MB | 1 |
| Nucci, TB | 1 |
| Margatho, LO | 1 |
| Antunes-Rodrigues, J | 1 |
| Renaud, J | 1 |
| Olivier, P | 1 |
| Di Fausto, V | 1 |
| Fiore, M | 1 |
| Tirassa, P | 1 |
| Lambiase, A | 1 |
| Aloe, L | 1 |
| Hattori, F | 1 |
| Oikawa, S | 1 |
| Harich, S | 1 |
| Auer, M | 1 |
| Schlager, G | 1 |
| Dimambro, N | 1 |
| Swarowsky, A | 1 |
| Rodrigues, L | 1 |
| Biasibetti, R | 1 |
| Leite, MC | 1 |
| de Oliveira, LF | 1 |
| de Almeida, LM | 1 |
| Gottfried, C | 1 |
| Quillfeldt, JA | 1 |
| Achaval, M | 1 |
| Gonçalves, CA | 1 |
| Lamarca, MV | 1 |
| Fibiger, HC | 1 |
| Zilles, K | 1 |
| Qü, M | 1 |
| Schleicher, A | 1 |
| Schroeter, M | 1 |
| Kraemer, M | 1 |
| Witte, OW | 2 |
| Ukai, M | 1 |
| Kobayashi, T | 1 |
| Kameyama, T | 1 |
| Wenk, GL | 2 |
| Lipska, BK | 2 |
| Jaskiw, GE | 1 |
| Weinberger, DR | 2 |
| Chambers, RA | 1 |
| Moore, J | 1 |
| McEvoy, JP | 1 |
| Evrard, P | 4 |
| Bhattacharya, SK | 1 |
| Sjöborg, M | 1 |
| Pietz, K | 1 |
| Ahgren, A | 1 |
| Yamada, N | 1 |
| Lindvall, O | 1 |
| Funa, K | 1 |
| Odin, P | 1 |
| Lamboley, G | 1 |
| Grecksch, G | 2 |
| Bernstein, HG | 1 |
| Becker, A | 2 |
| Höllt, V | 1 |
| Lacroix, L | 1 |
| Spinelli, S | 1 |
| White, W | 1 |
| Feldon, J | 1 |
| Hagemann, G | 1 |
| Redecker, C | 1 |
| Célérier, A | 1 |
| Ognard, R | 1 |
| Decorte, L | 1 |
| Beracochea, D | 1 |
| Eijkenboom, M | 1 |
| Blokland, A | 1 |
| van der Staay, FJ | 1 |
| Stine, CD | 1 |
| Lu, W | 1 |
| Wolf, ME | 1 |
| Kato, K | 1 |
| Shishido, T | 1 |
| Ono, M | 1 |
| Shishido, K | 1 |
| Kobayashi, M | 1 |
| Niwa, S | 1 |
| Kalin, NH | 1 |
| Shelton, SE | 1 |
| Davidson, RJ | 1 |
| Kelley, AE | 1 |
| Molteni, R | 1 |
| Racagni, G | 1 |
| Riva, MA | 1 |
| White, F | 1 |
| Nicoll, JA | 1 |
| Horsburgh, K | 1 |
| Patkai, J | 1 |
| Mesples, B | 2 |
| Fromont, G | 1 |
| Thornton, EM | 1 |
| Renauld, JC | 1 |
| Eid, T | 1 |
| Du, F | 1 |
| Schwarcz, R | 1 |
| Gerlai, RT | 1 |
| McNamara, A | 1 |
| Williams, S | 1 |
| Phillips, HS | 1 |
| DeGiorgio, LA | 1 |
| Attardi, B | 1 |
| Shimizu, Y | 1 |
| Ogata, M | 1 |
| Volpe, BT | 2 |
| Quian Quiroga, R | 1 |
| Kraskov, A | 1 |
| Kreuz, T | 1 |
| Grassberger, P | 1 |
| Le Pen, G | 1 |
| Gaudet, L | 1 |
| Mortas, P | 1 |
| Mory, R | 1 |
| Moreau, JL | 1 |
| Cotton, P | 1 |
| Davis, HP | 1 |
| Towle, A | 1 |
| Dunlap, WP | 1 |
| Beal, MF | 2 |
| Ferrante, RJ | 1 |
| Swartz, KJ | 1 |
| Kowall, NW | 1 |
| Farooqui, AA | 1 |
| Wallace, LJ | 1 |
| Horrocks, LA | 1 |
| Löschmann, PA | 1 |
| Lange, KW | 1 |
| Kunow, M | 1 |
| Rettig, KJ | 1 |
| Jähnig, P | 1 |
| Honoré, T | 1 |
| Turski, L | 1 |
| Wachtel, H | 1 |
| Jenner, P | 1 |
| Marsden, CD | 1 |
| Haroutunian, V | 1 |
| Santucci, AC | 1 |
| Davis, KL | 1 |
| Sirinathsinghji, DJ | 1 |
| Wisden, W | 1 |
| Northrop, A | 1 |
| Hunt, SP | 1 |
| Dunnett, SB | 3 |
| Morris, BJ | 1 |
| Hantraye, P | 2 |
| Riche, D | 2 |
| Maziere, M | 2 |
| Isacson, O | 5 |
| Sofroniew, MV | 1 |
| Thal, LJ | 1 |
| Mandel, RJ | 1 |
| Terry, RD | 1 |
| Buzsaki, G | 1 |
| Gage, FH | 2 |
| Bergman, H | 1 |
| Wichmann, T | 1 |
| DeLong, MR | 1 |
| Noble, EP | 1 |
| Ritchie, T | 1 |
| Marshall, PE | 1 |
| Burd, GD | 1 |
| Landis, DM | 1 |
| Martin, JB | 1 |
| Björklund, A | 4 |
| Emson, PC | 1 |
| Dawbarn, D | 1 |
| Rossor, MN | 1 |
| Rehfeld, JF | 1 |
| Hohmann, GF | 1 |
| Lowenstein, P | 1 |
| Brown, ME | 1 |
| Coyle, JT | 1 |
| Murphy, DE | 1 |
| Boast, CA | 1 |
| Fine, A | 1 |
| Iversen, SD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of N-acetylcysteine on Psychosis-like Symptoms and a Neurophysiological Biomarker of the Clinical High Risk for Schizophrenia[NCT05142735] | 90 participants (Anticipated) | Interventional | 2023-01-13 | Recruiting | |||
| Phase I Study of Subthalamic GAD Gene Transfer in Medically Refractory Parkinson's Disease Patients[NCT00195143] | Phase 1 | 12 participants | Interventional | 2003-08-31 | Completed | ||
| Differences in Voxel-based Morphometry of Different Brain Structures in Patients With Mood Disorder Bipolar Mania in Comparison to Morphometry of Nrmal Controls[NCT03181698] | 45 participants (Actual) | Observational | 2017-09-22 | Completed | |||
| NMDA-Receptor Blockade in Huntington's Chorea[NCT00001930] | Phase 2 | 25 participants | Interventional | 1999-04-30 | Completed | ||
| Dual Frequency, Dual Region Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease[NCT04650932] | 10 participants (Anticipated) | Interventional | 2022-10-22 | Recruiting | |||
| NMDA-Receptor Blockade With Eliprodil in Parkinson's Disease[NCT00001929] | Phase 2 | 20 participants | Interventional | 1999-03-31 | Completed | ||
| Can Subthreshold Transcranial Magnetic Stimulation (rTMS) to Motor Cortex and/or to Supplementary Motor Area (SMA) Improve Performance of Complex Motor Sequences in Parkinson's Disease?[NCT00001665] | 12 participants | Observational | 1997-01-31 | Completed | |||
| Convection Enhanced Delivery of Muscimol to Study the Pathophysiology Underlying the Clinical Features of Parkinson's Disease[NCT00921128] | Phase 1 | 0 participants (Actual) | Interventional | 2009-06-02 | Withdrawn | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for ibotenic acid and Disease Models, Animal
| Article | Year |
|---|---|
Neurodevelopmental animal models of schizophrenia: effects on prepulse inhibition.
Topics: Amygdala; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Aci | 2003 |
Peroxiredoxins in the central nervous system.
Topics: Adenoviridae; Animals; Central Nervous System Diseases; Disease Models, Animal; Excitatory Amino Aci | 2007 |
A primate model of Alzheimer's disease.
Topics: Acetylcholine; Alzheimer Disease; Animals; Attention; Brain; Cholinergic Fibers; Disease Models, Ani | 1993 |
Developmental spectrum of the excitotoxic cascade induced by ibotenate: a model of hypoxic insults in fetuses and neonates.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cricetinae; Disease Models, Animal; Embryo, Mammalian; Hy | 1996 |
Mechanisms and disturbances of neuronal migration.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Abnormalities, Multiple; Abnormalities, Radiation-In | 2000 |
155 other studies available for ibotenic acid and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
HJ22, a Novel derivative of piperine, Attenuates ibotenic acid-induced cognitive impairment, oxidativestress, apoptosis and inflammation via inhibiting the protein-protein interaction of Keap1-Nrf2.
Topics: Alkaloids; Animals; Apoptosis; Benzodioxoles; Cells, Cultured; Cognitive Dysfunction; Disease Models | 2020 |
Evaluation of the pre-treatment effect of Centella asiatica medicinal plants on long-term potentiation (LTP) in rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Basal Nucleus of Meynert; Disease Models, Animal; Hippocampus; Ibotenic | 2020 |
Ibotenic acid induced lesions impair the modulation of dendritic spine plasticity in the prefrontal cortex and amygdala, a phenomenon that underlies working memory and social behavior.
Topics: Amygdala; Animals; Behavior, Animal; Brain-Derived Neurotrophic Factor; Dendritic Spines; Disease Mo | 2021 |
Imbalance between dopamine and serotonin caused by neonatal habenula lesion.
Topics: Age Factors; Animals; Animals, Newborn; Astragalus propinquus; Attention Deficit Disorder with Hyper | 2021 |
Short-term deep brain stimulation of the thalamic reticular nucleus modifies aberrant oscillatory activity in a neurodevelopment model of schizophrenia.
Topics: Animals; Brain Waves; Deep Brain Stimulation; Disease Models, Animal; Electrocorticography; Female; | 2017 |
Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice.
Topics: Aging; Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Disease Models, Animal; Excitator | 2017 |
Basolateral amygdalar inactivation blocks chronic stress-induced lamina-specific reduction in prefrontal cortex volume and associated anxiety-like behavior.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear | 2019 |
Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury.
Topics: Animals; Animals, Newborn; Autophagy; Brain; Brain Injuries; Disease Models, Animal; Female; Iboteni | 2018 |
The increased expression of GABA receptors within the arcuate nucleus is associated with high intraocular pressure.
Topics: Animals; Apoptosis; Arcuate Nucleus of Hypothalamus; Disease Models, Animal; Excitatory Amino Acid A | 2018 |
Ameliorative effects of a combination of baicalin, jasminoidin and cholic acid on ibotenic acid-induced dementia model in rats.
Topics: Alzheimer Disease; Animals; Cholic Acid; Dementia; Disease Models, Animal; Drug Combinations; Drugs, | 2013 |
G protein-coupled receptor kinase 2 and group I metabotropic glutamate receptors mediate inflammation-induced sensitization to excitotoxic neurodegeneration.
Topics: Analysis of Variance; Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinas | 2013 |
Serotonergic neurons in the nucleus raphé obscurus are not involved in the ventilatory and thermoregulatory responses to hypoxia in adult rats.
Topics: Animals; Antibodies; Blood Gas Analysis; Body Temperature; Body Temperature Regulation; Cell Count; | 2013 |
Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.
Topics: Adult Stem Cells; Analysis of Variance; Animals; Basic Helix-Loop-Helix Transcription Factors; Brain | 2013 |
Impairments in set-shifting but not reversal learning in the neonatal ventral hippocampal lesion model of schizophrenia: further evidence for medial prefrontal deficits.
Topics: Animals; Attention; Disease Models, Animal; Hippocampus; Ibotenic Acid; Maze Learning; Prefrontal Co | 2013 |
The effect of treadmill running on memory before and after the NBM-lesion in rats.
Topics: Animals; Avoidance Learning; Basal Nucleus of Meynert; Cognition Disorders; Disease Models, Animal; | 2013 |
Intranasal nanoparticles of basic fibroblast growth factor for brain delivery to treat Alzheimer's disease.
Topics: Administration, Intranasal; Alzheimer Disease; Animals; Area Under Curve; Blood-Brain Barrier; Brain | 2014 |
Soyasaponin I improved neuroprotection and regeneration in memory deficient model rats.
Topics: Animals; Behavior, Animal; Biomarkers; Cell Differentiation; Cell Proliferation; Cells, Cultured; Di | 2013 |
Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brai | 2014 |
Contribution of anterior cingulate cortex and descending pain inhibitory system to analgesic effect of lemon odor in mice.
Topics: Administration, Inhalation; Affect; Animals; Aromatherapy; Benzazepines; Disease Models, Animal; Dop | 2014 |
Participation of the dorsal periaqueductal grey matter in the hypoxic ventilatory response in unanaesthetized rats.
Topics: Animals; Arterial Pressure; Body Temperature Regulation; Carbon Dioxide; Consciousness; Disease Mode | 2014 |
Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model.
Topics: Alzheimer Disease; Animals; Astrocytes; Cell Differentiation; Cell Line; Cell Proliferation; Cell- a | 2015 |
Increased expression of GAP43 in interneurons in a rat model of experimental polymicrogyria.
Topics: Animals; Animals, Newborn; Brain; Disease Models, Animal; Female; GAP-43 Protein; Ibotenic Acid; Int | 2015 |
The sigma-1 receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) protects against newborn excitotoxic brain injury by stabilizing the mitochondrial membrane potential in vitro and inhibiting microglial activation in vivo.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Inducing Factor; Brain Injuries; Caspase 3; Disease | 2014 |
SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer's disease induced by amyloid β and excitatory amino acids.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzamides; Cognition; Disease Models, Animal; Fe | 2014 |
Juvenile antioxidant treatment prevents adult deficits in a developmental model of schizophrenia.
Topics: Acetylcysteine; Animals; Animals, Newborn; Antioxidants; Disease Models, Animal; Dopamine Agonists; | 2014 |
Glial response in the rat models of functionally distinct cholinergic neuronal denervations.
Topics: Analysis of Variance; Animals; Brain Injuries; CD11b Antigen; Cholinergic Neurons; Denervation; Dise | 2015 |
3,4-dihydroxyphenylethanol attenuates spatio-cognitive deficits in an Alzheimer's disease mouse model: modulation of the molecular signals in neuronal survival-apoptotic programs.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cognition Disorders; Di | 2015 |
The anterior cingulate cortex is a critical hub for pain-induced depression.
Topics: Animals; Anxiety; Cerebral Cortex; Chronic Pain; Conditioning, Psychological; Depressive Disorder; D | 2015 |
Alleviating effects of Bushen-Yizhi formula on ibotenic acid-induced cholinergic impairments in rat.
Topics: Animals; Behavior, Animal; Brain; Cholinergic Fibers; Cholinesterases; Cognition; Cognition Disorder | 2015 |
Parabrachial lesions in rats disrupt sodium appetite induced by furosemide but not by calcium deprivation.
Topics: Analysis of Variance; Animals; Appetite; Calcium; Calcium Chloride; Conditioning, Psychological; Des | 2015 |
Neurodegeneration with inflammation is accompanied by accumulation of iron and ferritin in microglia and neurons.
Topics: Analysis of Variance; Animals; Antigens, CD; Brain; Disease Models, Animal; Ectodysplasins; Encephal | 2015 |
Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism.
Topics: Animals; Cell Survival; Cholinergic Neurons; Deep Brain Stimulation; Disease Models, Animal; Dopamin | 2015 |
Procedural Performance Benefits after Excitotoxic Hippocampal Lesions in the Rat Sequential Reaction Time Task.
Topics: Analysis of Variance; Animals; Brain Injuries; Conditioning, Operant; Disease Models, Animal; Excita | 2016 |
Deficits in hippocampal-dependent transfer generalization learning accompany synaptic dysfunction in a mouse model of amyloidosis.
Topics: Amyloid beta-Protein Precursor; Amyloidosis; Animals; Association; Disease Models, Animal; Female; H | 2016 |
Evidence for Competition for Target Innervation in the Medial Prefrontal Cortex.
Topics: Animals; Basolateral Nuclear Complex; Disease Models, Animal; Exploratory Behavior; Hippocampus; Ibo | 2016 |
Neonatal ventral hippocampus lesion changes nuclear restricted protein/brain (NRP/B) expression in hippocampus, cortex and striatum in developmental periods of rats.
Topics: Animals; Animals, Newborn; Blotting, Western; Cerebral Cortex; Corpus Striatum; Disease Models, Anim | 2016 |
Glial response to 17β-estradiol in neonatal rats with excitotoxic brain injury.
Topics: Adenomatous Polyposis Coli Protein; Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription | 2016 |
Dopamine D3 receptors modulate the rate of neuronal recovery, cell recruitment in Area X, and song tempo after neurotoxic damage in songbirds.
Topics: Animals; Avian Proteins; Cell Movement; Corpus Striatum; Disease Models, Animal; Dopamine Agents; Fi | 2016 |
Tracking recurrence of correlation structure in neuronal recordings.
Topics: Action Potentials; Animals; Brain; Disease Models, Animal; Electrocorticography; Epilepsy, Temporal | 2017 |
The effects of NBM- lesion on synaptic plasticity in rats.
Topics: Alzheimer Disease; Analysis of Variance; Animals; Basal Nucleus of Meynert; Dentate Gyrus; Disease M | 2017 |
The effects of neonatal amygdala or hippocampus lesions on adult social behavior.
Topics: Amygdala; Animal Communication; Animals; Animals, Newborn; Disease Models, Animal; Exploratory Behav | 2017 |
Thalamic pathology in sudden cardiac death in epilepsy: a shed light on mysterious event.
Topics: Animals; Brain; Death, Sudden, Cardiac; Disease Models, Animal; Epilepsy, Temporal Lobe; Heart Arres | 2008 |
Gossypium herbaceam extracts attenuate ibotenic acid-induced excitotoxicity in rat hippocampus.
Topics: Animals; bcl-2-Associated X Protein; Brain; Calbindin 1; Calbindins; Calcium-Transporting ATPases; C | 2009 |
Experimental neuronal migration disorders following the administration of ibotenate in hamsters: the role of the subventricular zone in the development of cortical dysplasia.
Topics: Animals; Animals, Newborn; Apoptosis; Biotin; Cell Movement; Cerebral Cortex; Cerebral Ventricles; C | 2009 |
Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Basal Nucleus of Meynert; Cerebral Cortex; Choline O-A | 2009 |
[An animal model of Huntington's disease: the development of histopathological changes within the neurotoxic lesions of the striatum in long-term surviving rats].
Topics: Animals; Corpus Striatum; Disease Models, Animal; Huntington Disease; Ibotenic Acid; Kainic Acid; Ne | 2002 |
Lesion-induced hippocampal plasticity in transgenic Alzheimer's disease mouse models: influences of age, genotype, and estrogen.
Topics: Acetylcholinesterase; Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Disea | 2009 |
The circuitry of atypical absence seizures in GABA(B)R1a transgenic mice.
Topics: Action Potentials; Animals; Behavior, Animal; Brain Mapping; Disease Models, Animal; Electroencephal | 2009 |
Disruption of mesolimbic regulation of prefrontal cholinergic transmission in an animal model of schizophrenia and normalization by chronic clozapine treatment.
Topics: Acetylcholine; Aging; Amphetamine; Animals; Animals, Newborn; Clozapine; Disease Models, Animal; Hip | 2009 |
Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats.
Topics: 5,7-Dihydroxytryptamine; Adrenergic Agents; Analysis of Variance; Animals; Benzylamines; Catheter Ab | 2010 |
Reduction of Prepulse Inhibition (PPI) after neonatal excitotoxic lesion of the ventral thalamus in pubertal and adult rats.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Antipsychotic Agents; Clozapine; Disease Models, Anim | 2010 |
The pontine respiratory group, particularly the Kölliker-Fuse nucleus, mediates phases of the hypoxic ventilatory response in unanesthetized goats.
Topics: Animals; Atropine; Basal Metabolism; Body Temperature Regulation; Consciousness; Disease Models, Ani | 2010 |
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Ste | 2010 |
Lovastatin improves neurological outcome after nucleus basalis magnocellularis lesion in rats.
Topics: Acetylcholine; Alzheimer Disease; Animals; Basal Nucleus of Meynert; Binding, Competitive; Cerebral | 2010 |
The effect of intra-hippocampal injection of growth hormone on spatial learning and memory in animal model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Growth Hormone; | 2009 |
In vivo assessment of experimental neonatal excitotoxic brain lesion with USPIO-enhanced MR imaging.
Topics: Animals; Animals, Newborn; Contrast Media; Dextrans; Disease Models, Animal; Humans; Ibotenic Acid; | 2010 |
Interhemispheric regulation of the medial prefrontal cortical glutamate stress response in rats.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Analysis of Variance; Animals; Baclofen; Benzazepines; Br | 2010 |
Transplantation of magnetically labeled mesenchymal stem cells in a model of perinatal brain injury.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Differentiation; Cell Proliferation; Disease Models, | 2010 |
Neuroprotective effects of NAP against excitotoxic brain damage in the newborn mice: implications for cerebral palsy.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Brain Injuries; Cerebral Palsy; Disease Mod | 2011 |
Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions.
Topics: Amphetamine; Animals; Animals, Newborn; Anti-Inflammatory Agents; Behavior, Animal; Cells, Cultured; | 2011 |
A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosi | 2011 |
Genetic inhibition of caspase-2 reduces hypoxic-ischemic and excitotoxic neonatal brain injury.
Topics: Animals; Animals, Newborn; Brain; Caspase 2; Cerebral Infarction; Disease Models, Animal; Female; Hy | 2011 |
Superior colliculus lesions impair threat responsiveness in infant capuchin monkeys.
Topics: Animals; Cebus; Conflict, Psychological; Disease Models, Animal; Escape Reaction; Fear; Feeding Beha | 2011 |
Enhancement of nose-to-brain delivery of basic fibroblast growth factor for improving rat memory impairments induced by co-injection of β-amyloid and ibotenic acid into the bilateral hippocampus.
Topics: Acetylcholinesterase; Administration, Intranasal; Aerosols; Amyloid beta-Peptides; Animals; Blood-Br | 2012 |
Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: involvement of MAPK signal pathway.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Apoptosis; Brain; Choline O-Acetyltransferase; Cogniti | 2012 |
Altered distribution of inhibitory interneurons in polymicrogyria.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Corpus Callosum; Cricetinae; Disease Models, Animal; Epi | 2012 |
Yohimbine anxiogenesis in the elevated plus maze is disrupted by bilaterally disconnecting the bed nucleus of the stria terminalis from the central nucleus of the amygdala.
Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Denervation; Disease Models, | 2012 |
Early cognitive experience prevents adult deficits in a neurodevelopmental schizophrenia model.
Topics: Animals; Animals, Newborn; Avoidance Learning; Brain Waves; Cell Count; Cognition Disorders; Cogniti | 2012 |
Chronic administration of risperidone in a rat model of schizophrenia: a behavioural, morphological and molecular study.
Topics: Age Factors; Animals; Animals, Newborn; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; | 2013 |
Epileptiform activity extinguished by amygdala infusion of the neurotoxin ibotenate in a rat model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Excitato | 2002 |
Glucocorticoid treatment in an ischaemic-like excitotoxic model of periventricular leucomalacia in mice.
Topics: Animals; Betamethasone; Brain Ischemia; Dexamethasone; Disease Models, Animal; Dose-Response Relatio | 2002 |
Subthalamic GAD gene therapy in a Parkinson's disease rat model.
Topics: Animals; Dependovirus; Disease Models, Animal; Dopamine; Electric Stimulation; Electrophysiology; ga | 2002 |
Delayed mesolimbic system alteration in a developmental animal model of schizophrenia.
Topics: Administration, Oral; Age Factors; Animals; Animals, Newborn; Corpus Striatum; Disease Models, Anima | 2002 |
Effects of a mediodorsal thalamus lesion on prefrontal inhibitory circuitry: implications for schizophrenia.
Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Glutamate Decarboxylase; Ibotenic A | 2003 |
The effect on motor cortical neuronal development of focal lesions to the sub-cortical white matter in the neonatal rat: a model for periventricular leukomalacia.
Topics: Animals; Animals, Newborn; Apoptosis; Axons; Disease Models, Animal; Humans; Ibotenic Acid; Infant, | 2003 |
Potent mammalian cerebroprotection and neuronal cell death inhibition are afforded by a synthetic antioxidant analogue of marine invertebrate cell protectant ovothiols.
Topics: Animals; Animals, Newborn; Behavior, Animal; Benzimidazoles; Brain; Brain Injuries; Cell Death; Dise | 2003 |
Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cues; Disease Models, Animal; Eating; Environmen | 2003 |
Early microglial activation following neonatal excitotoxic brain damage in mice: a potential target for neuroprotection.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Antirheumatic Agents; Brain; Brain Injuries; Cell | 2003 |
Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions.
Topics: Animals; Animals, Newborn; Brain Diseases; Cysts; Disease Models, Animal; Dose-Response Relationship | 2004 |
Argyrophilic dark neurons represent various states of neuronal damage in brain insults: some come to die and others survive.
Topics: Animals; Brain; Brain Diseases; Brain Injuries; Caspase 3; Caspases; Cell Death; Cytoskeleton; Dendr | 2004 |
Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model.
Topics: Alzheimer Disease; Animals; Blotting, Western; Brain; Disease Models, Animal; Dopamine Agents; Elect | 2004 |
Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Cognition; Conditioning, Operant; Disease Models, Ani | 2004 |
Behavioral and neurochemical effects of the intrahippocampal co-injection of beta-amyloid protein 1-40 and ibotenic acid in rats.
Topics: Amyloid beta-Peptides; Animals; Avoidance Learning; Disease Models, Animal; Exploratory Behavior; Hi | 2004 |
[Protective effects of Panax notoginseng saponins against pathological lesion of cholinergic neuron in rat model with Alzheimer' s disease].
Topics: Alzheimer Disease; Animals; Choline O-Acetyltransferase; Cholinergic Fibers; Disease Models, Animal; | 2005 |
Topiramate prevents excitotoxic damage in the newborn rodent brain.
Topics: Alanine; Animals; Animals, Newborn; Brain; Cerebral Palsy; Disease Models, Animal; Dose-Response Rel | 2005 |
A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models.
Topics: Acetylcholinesterase; Age Factors; Amyloid beta-Peptides; Animals; Autoradiography; Brain; Disease M | 2005 |
Effects of clozapine on memory function in the rat neonatal hippocampal lesion model of schizophrenia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Clozapine; Disease Models, An | 2006 |
Effects of hippocampal lesions on the monkey's ability to learn large sets of object-place associations.
Topics: Animals; Denervation; Disease Models, Animal; Female; Hippocampus; Ibotenic Acid; Learning; Macaca m | 2006 |
Neonatal lesions of the ventral hippocampus in rats lead to prefrontal cognitive deficits at two maturational stages.
Topics: Aging; Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Denervation; Disease Mode | 2006 |
Effects of hippocampal lesions on conditional discriminations in rats.
Topics: Animals; Conditioning, Psychological; Cues; Denervation; Discrimination Learning; Disease Models, An | 2006 |
Treatment-induced prevention of learning deficits in newborn mice with brain lesions.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain Injuries; Conditioning, Classical; Discrimination | 2006 |
Effects of Yukmijihwang-tang derivatives (YMJd) on ibotenic acid-induced amnesia in the rat.
Topics: Amnesia; Animals; Choline O-Acetyltransferase; Disease Models, Animal; Ibotenic Acid; Male; Maze Lea | 2006 |
Cognitive dysfunction induced by sequential injection of amyloid-beta and ibotenate into the bilateral hippocampus; protection by memantine and MK-801.
Topics: Amyloid beta-Peptides; Animals; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid A | 2006 |
Erythropoietin is neuroprotective against NMDA-receptor-mediated excitotoxic brain injury in newborn mice.
Topics: Animals; Animals, Newborn; Brain; Cytoprotection; Disease Models, Animal; Drug Administration Schedu | 2006 |
Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice.
Topics: Animals; Animals, Newborn; Brain; Cerebral Palsy; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinop | 2007 |
Unilateral ibotenic acid lesions of the prefrontal cortex reduce rotational behavior in 6-hydroxydopamine-lesioned rats.
Topics: Adrenergic Agents; Animals; Behavior, Animal; Disease Models, Animal; Excitatory Amino Acid Agonists | 2006 |
T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice.
Topics: Analysis of Variance; Animals; Animals, Newborn; Apoptosis; Caspase 3; Disease Models, Animal; Dose- | 2007 |
Role of tissue-plasminogen activator (t-PA) in a mouse model of neonatal white matter lesions: interaction with plasmin inhibitors and anti-inflammatory drugs.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Injuries; Cysts; Disease Models, Animal; Dose | 2007 |
Heparan sulfate mediates neuroprotection from degeneration in experimental glutaric aciduria.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Antimetabolites; Brain; Bromodeoxyuridine; Child; Dis | 2007 |
Sleep and EEG profile in neonatal hippocampal lesion model of schizophrenia.
Topics: Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Electroencephalography; Electromyogr | 2007 |
The effects of chronic estradiol treatment on working memory deficits induced by combined infusion of beta-amyloid (1-42) and ibotenic acid.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Disease Models, Animal; Est | 2007 |
Raphe magnus nucleus is involved in ventilatory but not hypothermic response to CO2.
Topics: Animals; Carbon Dioxide; Disease Models, Animal; Excitatory Amino Acid Agonists; Hypercapnia; Hyperv | 2007 |
Melatonin prevents learning disorders in brain-lesioned newborn mice.
Topics: Animals; Animals, Newborn; Central Nervous System Depressants; Conditioning, Psychological; Disease | 2007 |
Eye drop NGF administration promotes the recovery of chemically injured cholinergic neurons of adult mouse forebrain.
Topics: Acetylcholine; Animals; Basal Nucleus of Meynert; Cerebral Cortex; Choline O-Acetyltransferase; Chol | 2007 |
Effects of repeated dizocilpine treatment on adult rat behavior after neonatal lesions of the entorhinal cortex.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Animals, Newborn; Behavior, Animal; Brain Injur | 2008 |
Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain.
Topics: Animals; Animals, Newborn; Apoptosis; Brain; Caspase 3; Dextromethorphan; Disease Models, Animal; En | 2008 |
A comparison of behavioural and histological outcomes of periventricular injection of ibotenic acid in neonatal rats at postnatal days 5 and 7.
Topics: Animals; Animals, Newborn; Atrophy; Brain; Cerebral Cortex; Cerebral Palsy; Corpus Callosum; Disease | 2008 |
Glial alterations in the hippocampus of rats submitted to ibotenic-induced lesion of the nucleus basalis magnocellularis.
Topics: Animals; Astrocytes; Avoidance Learning; Basal Nucleus of Meynert; Brain Damage, Chronic; Cell Count | 2008 |
Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis.
Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransfer | 1984 |
Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts.
Topics: Alzheimer Disease; Animals; Autoradiography; Brain Diseases; Cerebral Cortex; Cerebral Infarction; D | 1995 |
Dynorphin A-(1-13) attenuates basal forebrain-lesion-induced amnesia in rats.
Topics: Alzheimer Disease; Amnesia; Animals; Avoidance Learning; Cognition; Disease Models, Animal; Dynorphi | 1993 |
Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of schizophrenia.
Topics: Animals; Animals, Newborn; Dextroamphetamine; Disease Models, Animal; Female; Haloperidol; Hippocamp | 1993 |
Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Diseases; Central Nervous System Stimulants; Disease M | 1996 |
Effect of Trasina, an ayurvedic herbal formulation, on experimental models of Alzheimer's disease and central cholinergic markers in rats.
Topics: Acetylcholine; Alzheimer Disease; Animals; Binding Sites; Choline O-Acetyltransferase; Cholinergic A | 1997 |
Expression of platelet-derived growth factor after intrastriatal ibotenic acid injury.
Topics: Animals; Corpus Striatum; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Hunting | 1998 |
[Prenatal inhibition of intestinal vasoactive peptide and cerebral excitatory lesions in the newborn mouse].
Topics: Animals; Animals, Newborn; Cerebral Palsy; Disease Models, Animal; Drug Evaluation, Preclinical; Emb | 1999 |
Disruption of latent inhibition in rats with postnatal hippocampal lesions.
Topics: Anesthesia; Animals; Apomorphine; Cognition Disorders; Conditioning, Psychological; Disease Models, | 1999 |
Social memory is impaired in neonatally ibotenic acid lesioned rats.
Topics: Animals; Animals, Newborn; Brain Mapping; Disease Models, Animal; Excitatory Amino Acid Antagonists; | 2000 |
The effects of ibotenic acid lesions of the medial and lateral prefrontal cortex on latent inhibition, prepulse inhibition and amphetamine-induced hyperlocomotion.
Topics: Amphetamine; Animals; Denervation; Disease Models, Animal; Dopamine; Hyperkinesis; Ibotenic Acid; Ma | 2000 |
Intact functional inhibition in the surround of experimentally induced focal cortical dysplasias in rats.
Topics: Animals; Animals, Newborn; Cerebral Cortex; Disease Models, Animal; Electrophysiology; Epilepsy; Exc | 2000 |
Deficits of spatial and non-spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption.
Topics: Acoustic Stimulation; Aging; Alcohol Amnestic Disorder; Alcoholism; Animals; Auditory Cortex; Behavi | 2000 |
Modelling cognitive dysfunctions with bilateral injections of ibotenic acid into the rat entorhinal cortex.
Topics: Brain Injuries; Cognition Disorders; Disease Models, Animal; Entorhinal Cortex; Functional Lateralit | 2000 |
Expression of AMPA receptor flip and flop mRNAs in the nucleus accumbens and prefrontal cortex after neonatal ventral hippocampal lesions.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Disease Models, Animal; Excitatory Amino Acids; | 2001 |
Glycine reduces novelty- and methamphetamine-induced locomotor activity in neonatal ventral hippocampal damaged rats.
Topics: Animals; Disease Models, Animal; Glycine; Hippocampus; Hyperkinesis; Ibotenic Acid; Methamphetamine; | 2001 |
The primate amygdala mediates acute fear but not the behavioral and physiological components of anxious temperament.
Topics: Aggression; Amygdala; Animals; Anxiety Disorders; Behavior, Animal; Disease Models, Animal; Electroe | 2001 |
Developmental and stress-related changes of neurotrophic factor gene expression in an animal model of schizophrenia.
Topics: Animals; Brain Chemistry; Brain-Derived Neurotrophic Factor; Denervation; Disease Models, Animal; Ex | 2001 |
Alterations in ApoE and ApoJ in relation to degeneration and regeneration in a mouse model of entorhinal cortex lesion.
Topics: Animals; Apolipoproteins E; Clusterin; Dentate Gyrus; Disease Models, Animal; Entorhinal Cortex; Fun | 2001 |
Deleterious effects of IL-9-activated mast cells and neuroprotection by antihistamine drugs in the developing mouse brain.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cerebral Palsy; Cromolyn Sodium; Disease Models, | 2001 |
Ibotenate injections into the pre- and parasubiculum provide partial protection against kainate-induced epileptic damage in layer III of rat entorhinal cortex.
Topics: Animals; Convulsants; Disease Models, Animal; Entorhinal Cortex; Epilepsy; Epilepsy, Temporal Lobe; | 2001 |
Melatoninergic neuroprotection of the murine periventricular white matter against neonatal excitotoxic challenge.
Topics: Animals; Animals, Newborn; Antioxidants; Cell Death; Cerebral Palsy; Cystine; Denervation; Disease M | 2002 |
Hippocampal dysfunction and behavioral deficit in the water maze in mice: an unresolved issue?
Topics: Animals; Behavior, Animal; Brain Injuries; Disease Models, Animal; Excitatory Amino Acid Agonists; F | 2002 |
17 beta-estradiol treatment retards excitotoxic delayed degeneration in substantia nigra reticulata neurons.
Topics: Animals; Cell Count; Cell Death; Corpus Striatum; Disease Models, Animal; Estradiol; Female; Functio | 2002 |
Performance of different synchronization measures in real data: a case study on electroencephalographic signals.
Topics: Animals; Brain Injuries; Cortical Synchronization; Disease Models, Animal; Epilepsy, Absence; Humans | 2002 |
Deficits in reward sensitivity in a neurodevelopmental rat model of schizophrenia.
Topics: Age Factors; Animals; Animals, Newborn; Conditioning, Psychological; Disease Models, Animal; Female; | 2002 |
Neuroscientists begin to piece together more parts of Huntington's disease puzzle.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Biomarkers; Brain Chemistry; Dise | 1992 |
Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions.
Topics: Animals; Appetitive Behavior; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Discrimination L | 1992 |
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Biogenic Amines; Cerebra | 1991 |
Stimulation of mono- and diacylglycerol lipase activities in ibotenate-induced lesions of nucleus basalis magnocellularis.
Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain; Cell Membrane; Disease Models, Animal; Functional | 1991 |
Synergism of the AMPA-antagonist NBQX and the NMDA-antagonist CPP with L-dopa in models of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Ac | 1991 |
Implications of multiple transmitter system lesions for cholinomimetic therapy in Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Cerebral Cortex; Choline O-Ace | 1990 |
Cellular localisation of neurotransmitter mRNAs in striatal grafts.
Topics: Animals; Brain Tissue Transplantation; Corpus Striatum; Disease Models, Animal; DNA, Antisense; Feta | 1990 |
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Caudate Nucleus; Disease Models, Animal; Dys | 1990 |
Apomorphine-induced dyskinesias after excitotoxic caudate-putamen lesions and the effects of neural transplantation in non-human primates.
Topics: Animals; Apomorphine; Brain Tissue Transplantation; Caudate Nucleus; Corpus Striatum; Disease Models | 1990 |
Nucleus basalis lesions fail to induce senile plaques in the rat.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Basal Ganglia; Choline O-Acetyltransferase; Diseas | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Reversal of experimental parkinsonism by lesions of the subthalamic nucleus.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Chlorocebus aethiops; Disease Models, | 1990 |
Prenatal ethanol exposure reduces the effects of excitatory amino acids in the rat hippocampus.
Topics: Amino Acids; Animals; Disease Models, Animal; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Hip | 1989 |
Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease.
Topics: Animals; Brain; Corpus Striatum; Disease Models, Animal; Enkephalin, Leucine; Humans; Huntington Dis | 1985 |
Neural grafting in a rat model of Huntington's disease: progressive neurochemical changes after neostriatal ibotenate lesions and striatal tissue grafting.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Choline O-Acetyltransferase; Corpus Striatum; Disease Model | 1985 |
Graft-induced behavioral recovery in an animal model of Huntington disease.
Topics: Animals; Attention; Behavior, Animal; Cognition; Corpus Striatum; Disease Models, Animal; Globus Pal | 1986 |
Cholecystokinin content in the basal ganglia in Huntington's disease. The expression of cholecystokinin immunoreactivity in striatal grafts to ibotenic acid-lesioned rat striatum.
Topics: Animals; Basal Ganglia; Brain Chemistry; Cell Survival; Cholecystokinin; Corpus Striatum; Disease Mo | 1985 |
Age-related recurrence of basal forebrain lesion-induced cholinergic deficits.
Topics: Age Factors; Aging; Alzheimer Disease; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Cholin | 1987 |
Searching for models of Alzheimer's disease: a comparison of four amnestic treatments in two behavioral tasks.
Topics: Acetylcholine; Age Factors; Alzheimer Disease; Animals; Avoidance Learning; Behavior, Animal; Discri | 1985 |
Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Cholinergic Fibers; Disease Mo | 1985 |