Page last updated: 2024-10-21

ibotenic acid and Cognition Disorders

ibotenic acid has been researched along with Cognition Disorders in 14 studies

Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Ibotenic acid was injected bilaterally into the nucleus basalis of rats, which were distributed into three groups."1.33Regulatable acetylcholine-producing fibroblasts enhance cognitive performance. ( Coufal, NG; Gage, FH; Lortie, MJ; Pizzo, DP; Thal, LJ, 2006)
"Ibotenic acid was infused into the nucleus basalis magnocellularis (nBM) of 2-day old rats to eliminate immature cholinergic neurons before they develop functional synaptic connections in the neocortex."1.28Nucleus basalis lesions in neonate rats induce a selective cortical cholinergic hypofunction and cognitive deficits during adulthood. ( Arendash, GW; Dunn, AJ; Jantzen, PT; Johnson, KB; Meyer, EM; Sengstock, GJ, 1992)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hosseini, N1
Alaei, H1
Reisi, P1
Radahmadi, M1
Marei, HE1
Farag, A1
Althani, A1
Afifi, N1
Abd-Elmaksoud, A1
Lashen, S1
Rezk, S1
Pallini, R1
Casalbore, P1
Cenciarelli, C1
Arunsundar, M1
Shanmugarajan, TS1
Ravichandran, V1
Hou, XQ1
Zhang, L1
Yang, C1
Rong, CP1
He, WQ1
Zhang, CX1
Li, S1
Su, RY1
Chang, X1
Qin, JH1
Chen, YB1
Xian, SX1
Wang, Q1
Yu, X1
Wang, LN1
Ma, L1
You, R1
Cui, R1
Ji, D1
Wu, Y1
Zhang, CF1
Yang, ZL1
Ji, H1
Lee, HJ1
Lim, IJ1
Park, SW1
Kim, YB1
Ko, Y1
Kim, SU1
Lee, H1
Dvorak, D1
Kao, HY1
Duffy, ÁM1
Scharfman, HE1
Fenton, AA1
Spowart-Manning, L1
van der Staay, FJ2
Pizzo, DP1
Coufal, NG1
Lortie, MJ1
Gage, FH1
Thal, LJ1
Marquis, JP1
Goulet, S1
Doré, FY1
Grecksch, G1
Bernstein, HG1
Becker, A1
Höllt, V1
Bogerts, B1
Eijkenboom, M1
Blokland, A1
Chavoix, C1
Blaizot, X1
Meguro, K1
Landeau, B1
Baron, JC1
Sengstock, GJ1
Johnson, KB1
Jantzen, PT1
Meyer, EM1
Dunn, AJ1
Arendash, GW1

Other Studies

14 other studies available for ibotenic acid and Cognition Disorders

ArticleYear
The effect of treadmill running on memory before and after the NBM-lesion in rats.
    Journal of bodywork and movement therapies, 2013, Volume: 17, Issue:4

    Topics: Animals; Avoidance Learning; Basal Nucleus of Meynert; Cognition Disorders; Disease Models, Animal;

2013
Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model.
    Journal of cellular physiology, 2015, Volume: 230, Issue:1

    Topics: Alzheimer Disease; Animals; Astrocytes; Cell Differentiation; Cell Line; Cell Proliferation; Cell- a

2015
3,4-dihydroxyphenylethanol attenuates spatio-cognitive deficits in an Alzheimer's disease mouse model: modulation of the molecular signals in neuronal survival-apoptotic programs.
    Neurotoxicity research, 2015, Volume: 27, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Cell Survival; Cognition Disorders; Di

2015
Alleviating effects of Bushen-Yizhi formula on ibotenic acid-induced cholinergic impairments in rat.
    Rejuvenation research, 2015, Volume: 18, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Cholinergic Fibers; Cholinesterases; Cognition; Cognition Disorder

2015
Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: involvement of MAPK signal pathway.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Apoptosis; Brain; Choline O-Acetyltransferase; Cogniti

2012
Human neural stem cells genetically modified to express human nerve growth factor (NGF) gene restore cognition in the mouse with ibotenic acid-induced cognitive dysfunction.
    Cell transplantation, 2012, Volume: 21, Issue:11

    Topics: Animals; Astrocytes; Brain; Cell Line; Cells, Cultured; Cognition Disorders; Humans; Ibotenic Acid;

2012
Early cognitive experience prevents adult deficits in a neurodevelopmental schizophrenia model.
    Neuron, 2012, Aug-23, Volume: 75, Issue:4

    Topics: Animals; Animals, Newborn; Avoidance Learning; Brain Waves; Cell Count; Cognition Disorders; Cogniti

2012
Spatial discrimination deficits by excitotoxic lesions in the Morris water escape task.
    Behavioural brain research, 2005, Jan-30, Volume: 156, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Cholinesterase Inhibitors; Cognition Disorders; Dis

2005
Regulatable acetylcholine-producing fibroblasts enhance cognitive performance.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2006, Volume: 13, Issue:1

    Topics: Acetylcholine; Animals; Avoidance Learning; Brain; Cell Line; Choline O-Acetyltransferase; Cognition

2006
Neonatal lesions of the ventral hippocampus in rats lead to prefrontal cognitive deficits at two maturational stages.
    Neuroscience, 2006, Jul-07, Volume: 140, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Denervation; Disease Mode

2006
Disruption of latent inhibition in rats with postnatal hippocampal lesions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: Anesthesia; Animals; Apomorphine; Cognition Disorders; Conditioning, Psychological; Disease Models,

1999
Modelling cognitive dysfunctions with bilateral injections of ibotenic acid into the rat entorhinal cortex.
    Neuroscience, 2000, Volume: 101, Issue:1

    Topics: Brain Injuries; Cognition Disorders; Disease Models, Animal; Entorhinal Cortex; Functional Lateralit

2000
Excitotoxic lesions of the rhinal cortex in the baboon differentially affect visual recognition memory, habit memory and spatial executive functions.
    The European journal of neuroscience, 2002, Volume: 15, Issue:7

    Topics: Animals; Behavior, Animal; Cognition; Cognition Disorders; Entorhinal Cortex; Habits; Habituation, P

2002
Nucleus basalis lesions in neonate rats induce a selective cortical cholinergic hypofunction and cognitive deficits during adulthood.
    Experimental brain research, 1992, Volume: 90, Issue:1

    Topics: Acetylcholinesterase; Animals; Animals, Newborn; Avoidance Learning; Basal Ganglia; Behavior, Animal

1992