ibotenic acid has been researched along with Brain Ischemia in 11 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Rats were trained for 20 days in a modified T maze to perform an invariant, tactile discrimination and a variable, delayed spatial discrimination, and then were exposed either to 30 min of transient forebrain ischemia or to low- or high-dose ibotenic acid to damage the dorsal hippocampus bilaterally." | 3.68 | Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions. ( Davis, HP; Dunlap, WP; Towle, A; Volpe, BT, 1992) |
| "Reperfusion following transient global cerebral ischemia is characterized by an initial hyperemic phase, which precedes hypoperfusion." | 1.28 | The onset of postischemic hypoperfusion in rats is precipitous and may be controlled by local neurons. ( Feuerstein, GZ; Frerichs, KU; Hallenbeck, JM; Sirén, AL, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (63.64) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arquié, C | 1 |
| Leroux, P | 1 |
| Bodenant, C | 1 |
| Laquerrière, A | 1 |
| Marpeau, L | 1 |
| Marret, S | 2 |
| Yoneda, Y | 1 |
| Gressens, P | 1 |
| Evrard, P | 1 |
| Zola, SM | 2 |
| Squire, LR | 2 |
| Teng, E | 2 |
| Stefanacci, L | 2 |
| Buffalo, EA | 1 |
| Clark, RE | 1 |
| Glickstein, SB | 1 |
| Ilch, CP | 1 |
| Reis, DJ | 1 |
| Golanov, EV | 1 |
| Moncada, C | 1 |
| Lekieffre, D | 1 |
| Arvin, B | 1 |
| Meldrum, B | 1 |
| Frerichs, KU | 1 |
| Sirén, AL | 1 |
| Feuerstein, GZ | 1 |
| Hallenbeck, JM | 1 |
| Volpe, BT | 1 |
| Davis, HP | 1 |
| Towle, A | 1 |
| Dunlap, WP | 1 |
| Rogers, H | 1 |
| Birch, PJ | 1 |
| Hayes, AG | 1 |
| Sheardown, MJ | 1 |
| Nielsen, EO | 1 |
| Hansen, AJ | 1 |
| Jacobsen, P | 1 |
| Honoré, T | 1 |
2 reviews available for ibotenic acid and Brain Ischemia
| Article | Year |
|---|---|
[Receptive mechanisms of excitatory amino acid signals].
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Brain Ischemia; Ep | 1993 |
Developmental spectrum of the excitotoxic cascade induced by ibotenate: a model of hypoxic insults in fetuses and neonates.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cricetinae; Disease Models, Animal; Embryo, Mammalian; Hy | 1996 |
9 other studies available for ibotenic acid and Brain Ischemia
| Article | Year |
|---|---|
Glucocorticoid treatment in an ischaemic-like excitotoxic model of periventricular leucomalacia in mice.
Topics: Animals; Betamethasone; Brain Ischemia; Dexamethasone; Disease Models, Animal; Dose-Response Relatio | 2002 |
Impaired recognition memory in monkeys after damage limited to the hippocampal region.
Topics: Animals; Behavior, Animal; Brain Ischemia; Excitatory Amino Acid Agonists; Hippocampus; Ibotenic Aci | 2000 |
Contrasting effects on discrimination learning after hippocampal lesions and conjoint hippocampal-caudate lesions in monkeys.
Topics: Animals; Behavior, Animal; Brain Ischemia; Caudate Nucleus; Denervation; Discrimination Learning; Ex | 2000 |
Stimulation of the subthalamic vasodilator area and fastigial nucleus independently protects the brain against focal ischemia.
Topics: Animals; Brain Ischemia; Cerebellar Nuclei; Cerebrovascular Circulation; Denervation; Electric Stimu | 2001 |
Effect of NO synthase inhibition on NMDA- and ischaemia-induced hippocampal lesions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Argin | 1992 |
The onset of postischemic hypoperfusion in rats is precipitous and may be controlled by local neurons.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cerebrovascular Circulation; Ibotenic Acid; Lasers; | 1992 |
Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions.
Topics: Animals; Appetitive Behavior; Brain Damage, Chronic; Brain Ischemia; Brain Mapping; Discrimination L | 1992 |
Effects of hypoxia and hypoglycaemia on DC potentials recorded from the gerbil hippocampus in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Ischemia; Cell Hypoxia; gam | 1990 |
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Aspartic Acid; Brain Ischemia; Ce | 1990 |