ibotenic acid has been researched along with Brain Disorders in 56 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
Excerpt | Relevance | Reference |
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"The degenerative lesions of bilateral substantia nigra (SN) were made by means of microinjections of ibotenic acid (IBO) solutions and influences upon kainic acid (KA)-induced seizures were studied." | 3.67 | Ibotenic acid-induced nigral lesion and limbic seizure in cats. ( Kaijima, M; Tanaka, S; Tanaka, T; Yonemasu, Y, 1989) |
"The present study carried out a comparison of the most common scPCP dosing regimen with excitotoxin-induced medial prefrontal cortex (mPFC) dysfunction in rats, across several cognitive tests relevant to schizophrenia." | 1.42 | Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia. ( Bussey, TJ; Mar, AC; McAllister, KA; Saksida, LM; Theobald, DE, 2015) |
"Memory deficits as the first symptom of Alzheimer's disease can be explained by the initial lesion of the entorhinal-hippocampal connection." | 1.29 | Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts. ( Kraemer, M; Qü, M; Schleicher, A; Schroeter, M; Witte, OW; Zilles, K, 1995) |
" The antagonistic properties of kynurenate were dose-dependent: equimolar kynurenate had no effect on quinolinate but attenuated the actions of ibotenate, kainate and NMDA; 2 x equimolar kynurenate had no effect on quinolinate or ibotenate but attenuated the toxicity of kainate and NMDA; and 3 x equimolar kynurenate had no effect on the toxicity of kainate or ibotenate, attenuated the actions of NMDA and abolished the toxic action of quinolinate." | 1.28 | A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat. ( Clark, AJ; Hastings, MH; Latimer, M; Stone, TW; Winn, P, 1991) |
"The apomorphine test was highly reproducible and individual animals responded with a similar set and incidence of dyskinesia in successive tests." | 1.28 | A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon. ( Hantraye, P; Isacson, O; Maziere, M; Riche, D, 1990) |
"Pentobarbital treatment reduced 2-DG accumulation in all brain areas examined and these reductions were not influenced by the nBM lesions." | 1.27 | Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis. ( Fibiger, HC; Lamarca, MV, 1984) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 12 (21.43) | 18.7374 |
1990's | 19 (33.93) | 18.2507 |
2000's | 21 (37.50) | 29.6817 |
2010's | 4 (7.14) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Blaise, BJ | 1 |
Schwendimann, L | 2 |
Chhor, V | 1 |
Degos, V | 1 |
Hodson, MP | 1 |
Dallmann, G | 1 |
Keller, M | 1 |
Gressens, P | 8 |
Fleiss, B | 1 |
Petrovic, J | 1 |
Lazic, K | 1 |
Ciric, J | 1 |
Kalauzi, A | 1 |
Saponjic, J | 1 |
McAllister, KA | 1 |
Mar, AC | 1 |
Theobald, DE | 1 |
Saksida, LM | 1 |
Bussey, TJ | 1 |
Wesierska, M | 1 |
Adamska, I | 1 |
Malinowska, M | 1 |
Tait, DS | 1 |
Marston, HM | 2 |
Shahid, M | 1 |
Brown, VJ | 1 |
Peuser, J | 1 |
Belhaj-Saif, A | 1 |
Hamadjida, A | 1 |
Schmidlin, E | 1 |
Gindrat, AD | 1 |
Völker, AC | 1 |
Zakharov, P | 1 |
Hoogewoud, HM | 1 |
Rouiller, EM | 1 |
Scheffold, F | 1 |
Sziklas, V | 1 |
Petrides, M | 1 |
Bhardwaj, SK | 1 |
Quirion, R | 1 |
Srivastava, LK | 1 |
Hennebert, O | 2 |
Marret, S | 5 |
Carmeliet, P | 2 |
Laquerrière, A | 3 |
Leroux, P | 3 |
Maetzler, W | 1 |
Nitsch, C | 2 |
Bendfeldt, K | 1 |
Racay, P | 1 |
Vollenweider, F | 1 |
Schwaller, B | 1 |
Takano, T | 1 |
Sawai, C | 1 |
Takeuchi, Y | 1 |
Célérier, A | 1 |
Pierard, C | 1 |
Beracochea, D | 1 |
Ishida, K | 1 |
Shimizu, H | 1 |
Hida, H | 1 |
Urakawa, S | 1 |
Ida, K | 1 |
Nishino, H | 1 |
Al Amin, HA | 1 |
Atweh, SF | 1 |
Jabbur, SJ | 1 |
Saadé, NE | 1 |
Laudenbach, V | 2 |
Verney, C | 1 |
Ramos, M | 1 |
Goñi-Allo, B | 1 |
Aguirre, N | 1 |
Antoniadis, EA | 1 |
Winslow, JT | 1 |
Davis, M | 1 |
Amaral, DG | 1 |
Rangon, CM | 1 |
Fortes, S | 1 |
Lelièvre, V | 1 |
Plaisant, F | 1 |
Joubert, C | 1 |
Lanfumey, L | 1 |
Cohen-Salmon, C | 1 |
Klein, S | 1 |
Koch, M | 1 |
Schwabe, K | 1 |
Husson, I | 1 |
Sarkozy, G | 1 |
Mocaer, E | 1 |
Vamecq, J | 1 |
Spedding, M | 1 |
Schwarcz, R | 1 |
Collins, JF | 1 |
Parks, DA | 1 |
Winn, P | 2 |
Tarbuck, A | 1 |
Dunnett, SB | 5 |
Lamarca, MV | 1 |
Fibiger, HC | 1 |
London, ED | 1 |
McKinney, M | 1 |
Dam, M | 1 |
Ellis, A | 1 |
Coyle, JT | 1 |
Frey, KA | 1 |
Agranoff, BW | 1 |
Saura, J | 1 |
Boatell, ML | 2 |
Bendahan, G | 2 |
Mahy, N | 2 |
Fischer, S | 1 |
Wolf, G | 1 |
Keilhoff, G | 1 |
Hass, P | 1 |
Hantraye, P | 2 |
Guibert, B | 1 |
Biguet, NF | 1 |
Lavergne, A | 1 |
Leviel, V | 1 |
Fricker, RA | 1 |
Torres, EM | 1 |
Lombroso, PJ | 1 |
Mukendi, R | 1 |
Gadisseux, JF | 1 |
Evrard, P | 4 |
Zilles, K | 1 |
Qü, M | 1 |
Schleicher, A | 1 |
Schroeter, M | 1 |
Kraemer, M | 1 |
Witte, OW | 1 |
Yamamoto, T | 1 |
Fujimoto, Y | 1 |
Shimura, T | 1 |
Sakai, N | 1 |
Pschorn, U | 1 |
Körperich, H | 1 |
Heymans, L | 1 |
Subramanian, S | 1 |
Kuhn, W | 1 |
Ben-Horin, N | 1 |
Hazvi, S | 1 |
Bendel, P | 1 |
Schul, R | 1 |
Chambers, RA | 1 |
Moore, J | 1 |
McEvoy, JP | 1 |
Levin, ED | 1 |
Martin, JL | 1 |
Lombet, A | 1 |
Bernstein, HG | 1 |
Grecksch, G | 1 |
Becker, A | 1 |
Höllt, V | 1 |
Bogerts, B | 1 |
Arquié, C | 1 |
Hill, JM | 1 |
Sahir, N | 1 |
Robberecht, P | 1 |
Baxter, MG | 1 |
Murray, EA | 1 |
Muñoz, A | 1 |
Lopez, A | 1 |
Caruncho, HJ | 1 |
Guerra, MJ | 1 |
Labandeira-García, JL | 1 |
Medja, F | 1 |
Zoli, M | 1 |
Rossi, FM | 1 |
Changeux, JP | 1 |
Dayas, CV | 1 |
Day, TA | 1 |
Scotti, AL | 1 |
McDonald, JW | 1 |
Johnston, MV | 1 |
Stone, TW | 1 |
Latimer, M | 1 |
Hastings, MH | 1 |
Clark, AJ | 1 |
Ray, PG | 1 |
Jackson, WJ | 1 |
Ebert, B | 1 |
Madsen, U | 1 |
Johansen, TN | 1 |
Krogsgaard-Larsen, P | 1 |
Riche, D | 1 |
Maziere, M | 1 |
Isacson, O | 4 |
Robbins, TW | 1 |
Everitt, BJ | 1 |
Ryan, CN | 1 |
Jones, GH | 1 |
Page, KJ | 1 |
Tanaka, T | 1 |
Tanaka, S | 1 |
Kaijima, M | 1 |
Yonemasu, Y | 1 |
Sirinathsinghji, DJ | 1 |
Clarke, DJ | 2 |
Björklund, A | 4 |
Wictorin, K | 1 |
Fischer, W | 1 |
Nothias, F | 1 |
Peschanski, M | 1 |
Cross, AJ | 1 |
Deakin, JF | 1 |
Fine, A | 1 |
Clarke, D | 1 |
Iversen, SD | 1 |
2 reviews available for ibotenic acid and Brain Disorders
Article | Year |
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NMDA receptor agonists: relationships between structure and biological activity.
Topics: Amino Acids; Animals; Brain Diseases; Carboxylic Acids; Humans; Ibotenic Acid; Piperidines; Receptor | 1991 |
Striatal grafts in the ibotenic acid-lesioned neostriatum: functional studies.
Topics: Animals; Brain Diseases; Corpus Striatum; Dopamine; gamma-Aminobutyric Acid; Globus Pallidus; Iboten | 1988 |
54 other studies available for ibotenic acid and Brain Disorders
Article | Year |
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Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury.
Topics: Animals; Animals, Newborn; Brain Diseases; Excitatory Amino Acid Agonists; Female; Ibotenic Acid; Ma | 2017 |
Topography of the sleep/wake states related EEG microstructure and transitions structure differentiates the functionally distinct cholinergic innervation disorders in rat.
Topics: Animals; Basal Nucleus of Meynert; Beta Rhythm; Brain; Brain Diseases; Cholinergic Neurons; Electroe | 2013 |
Comparing the effects of subchronic phencyclidine and medial prefrontal cortex dysfunction on cognitive tests relevant to schizophrenia.
Topics: Animals; Behavior, Animal; Brain Diseases; Cognition; Excitatory Amino Acid Agonists; Hallucinogens; | 2015 |
Retrosplenial cortex lesion affected segregation of spatial information in place avoidance task in the rat.
Topics: Analysis of Variance; Animals; Avoidance Learning; Brain Diseases; Cerebral Cortex; Electroshock; Ib | 2009 |
Asenapine restores cognitive flexibility in rats with medial prefrontal cortex lesions.
Topics: Animals; Brain Diseases; Brain Mapping; Cognition; Dibenzocycloheptenes; Discrimination Learning; Ex | 2009 |
Follow-up of cortical activity and structure after lesion with laser speckle imaging and magnetic resonance imaging in nonhuman primates.
Topics: Animals; Brain Diseases; Cerebrovascular Circulation; Diagnostic Imaging; Histocytochemistry; Iboten | 2011 |
Effects of lesions to the hippocampus or the fornix on allocentric conditional associative learning in rats.
Topics: Animals; Association Learning; Behavior, Animal; Brain Diseases; Conditioning, Psychological; Cues; | 2002 |
Post-pubertal adrenergic changes in rats with neonatal lesions of the ventral hippocampus.
Topics: Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Brain Di | 2004 |
Role of tissue-derived plasminogen activator (t-PA) in an excitotoxic mouse model of neonatal white matter lesions.
Topics: Animals; Animals, Newborn; Brain Diseases; Cysts; Disease Models, Animal; Dose-Response Relationship | 2004 |
Ectopic parvalbumin expression in mouse forebrain neurons increases excitotoxic injury provoked by ibotenic acid injection into the striatum.
Topics: Animals; Astrocytes; Blotting, Western; Brain Diseases; Cell Death; Cell Survival; Corpus Striatum; | 2004 |
Radial and tangential neuronal migration disorder in ibotenate-induced cortical lesions in hamsters: immunohistochemical study of reelin, vimentin, and calretinin.
Topics: Animals; Animals, Newborn; Brain Diseases; Cell Adhesion Molecules, Neuronal; Cell Movement; Cerebra | 2004 |
Effects of ibotenic acid lesions of the dorsal hippocampus on contextual fear conditioning in mice: comparison with mammillary body lesions.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Brain D | 2004 |
Argyrophilic dark neurons represent various states of neuronal damage in brain insults: some come to die and others survive.
Topics: Animals; Brain; Brain Diseases; Brain Injuries; Caspase 3; Caspases; Cell Death; Cytoskeleton; Dendr | 2004 |
Effects of ventral hippocampal lesion on thermal and mechanical nociception in neonates and adult rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain Diseases; Female; Hippocampus; Hot T | 2004 |
Ontogenic study of the influence of tissue plasminogen activator (t-PA) in neonatal excitotoxic brain insult and the subsequent microglia/macrophage activation.
Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Brain Diseases; Dose-Response Relationship, Drug; | 2005 |
Ibotenic acid lesions of the medial prefrontal cortex block the development and expression of 3,4-methylenedioxymethamphetamine-induced behavioral sensitization in rats.
Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Behavior, Animal; Brain Diseases; Drug | 2005 |
Role of the primate amygdala in fear-potentiated startle: effects of chronic lesions in the rhesus monkey.
Topics: Amygdala; Animals; Brain Diseases; Conditioning, Psychological; Fear; Hippocampus; Ibotenic Acid; Ma | 2007 |
Chronic mild stress during gestation worsens neonatal brain lesions in mice.
Topics: Animals; Animals, Newborn; Brain; Brain Diseases; Chronic Disease; Corticosterone; Epilepsy; Female; | 2007 |
Neuroanatomical changes in the adult rat brain after neonatal lesion of the medial prefrontal cortex.
Topics: Afferent Pathways; Animals; Animals, Newborn; Brain; Brain Diseases; Coloring Agents; DNA-Binding Pr | 2008 |
Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity.
Topics: Acetamides; Animals; Brain; Brain Diseases; Excitatory Amino Acid Agonists; Ibotenic Acid; Melatonin | 2008 |
alpha-Amino-omega-phosphono carboxylates block ibotenate but not kainate neurotoxicity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Diseases; Hippocampus; Ibotenic Acid; Kaini | 1982 |
Ibotenic acid lesions of the lateral hypothalamus: comparison with the electrolytic lesion syndrome.
Topics: Animals; Body Weight; Brain Chemistry; Brain Diseases; Dopamine; Drinking; Eating; Hypothalamic Area | 1984 |
Deoxyglucose uptake and choline acetyltransferase activity in cerebral cortex following lesions of the nucleus basalis magnocellularis.
Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransfer | 1984 |
Decreased cortical glucose utilization after ibotenate lesion of the rat ventromedial globus pallidus.
Topics: Alzheimer Disease; Animals; Autoradiography; Brain Diseases; Cerebral Cortex; Globus Pallidus; Gluco | 1984 |
Barbiturate-enhanced detection of brain lesions by carbon-14-labeled 2-deoxyglucose autoradiography.
Topics: Animals; Autoradiography; Barbiturates; Brain; Brain Diseases; Corpus Striatum; Deoxyglucose; Glucos | 1983 |
Calcium deposit formation and glial reaction in rat brain after ibotenic acid-induced basal forebrain lesion.
Topics: Animals; Autoradiography; Brain; Brain Diseases; Calcium; Ibotenic Acid; Male; Monoamine Oxidase; Ne | 1995 |
Mg2+ antagonizes alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-induced brain damage and convulsions.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain Diseases; Ibotenic Acid; Ma | 1993 |
TH mRNA over-expression in rats with chronic excitotoxic striatal lesions.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Diseases; Caudate Nucleus; Chronic Disease; Co | 1994 |
The localization of an antibody to STEP in embryonic striatal tissue grafts.
Topics: Acetylcholinesterase; Animals; Brain Diseases; Corpus Striatum; Dopamine and cAMP-Regulated Phosphop | 1994 |
Effect of ibotenate on brain development: an excitotoxic mouse model of microgyria and posthypoxic-like lesions.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Amino Acids; Animals; Brain; Brain Diseases; Embryonic and Fet | 1995 |
Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts.
Topics: Alzheimer Disease; Animals; Autoradiography; Brain Diseases; Cerebral Cortex; Cerebral Infarction; D | 1995 |
Conditioned taste aversion in rats with excitotoxic brain lesions.
Topics: Animals; Avoidance Learning; Brain; Brain Diseases; Ibotenic Acid; Lithium Chloride; Male; Memory; R | 1995 |
Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study.
Topics: Alzheimer Disease; Amino Acids; Animals; Brain Diseases; Cerebral Cortex; Chromatography, High Press | 1995 |
MRI and MRS studies on the time course of rat brain lesions and the effect of drug treatment: volume quantification and characterization of tissue heterogeneity by parameter selection.
Topics: Animals; Brain Diseases; Dizocilpine Maleate; Ibotenic Acid; Magnetic Resonance Imaging; Magnetic Re | 1993 |
The ontogeny of a neurotoxic lesion in rat brain revealed by combined MRI and histology.
Topics: Animals; Brain; Brain Diseases; Electron Transport Complex IV; Excitatory Amino Acid Agonists; Histo | 1996 |
Cognitive effects of neonatal hippocampal lesions in a rat model of schizophrenia.
Topics: Amphetamine; Animals; Behavior, Animal; Brain Diseases; Central Nervous System Stimulants; Disease M | 1996 |
Regulation of neuroprotective action of vasoactive intestinal peptide in the murine developing brain by protein kinase C and mitogen-activated protein kinase cascades: in vivo and in vitro studies.
Topics: Animals; Animals, Newborn; Astrocytes; Axons; Brain; Brain Diseases; Calcium-Calmodulin-Dependent Pr | 1998 |
Cellular changes in rat brain areas associated with neonatal hippocampal damage.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Diseases; Calbindin 2; Excitatory Amino Acid Agonists | 1999 |
VIP and PACAP 38 modulate ibotenate-induced neuronal heterotopias in the newborn hamster neocortex.
Topics: Animals; Animals, Newborn; Binding Sites; Brain Diseases; Choristoma; Cricetinae; Drug Synergism; Ib | 2000 |
Impairments in visual discrimination learning and recognition memory produced by neurotoxic lesions of rhinal cortex in rhesus monkeys.
Topics: Animals; Brain Diseases; Brain Mapping; Discrimination, Psychological; Ibotenic Acid; Learning; Maca | 2001 |
Long-term cortical atrophy after excitotoxic striatal lesion: effects of intrastriatal fetal-striatum grafts and implications for Huntington disease.
Topics: Animals; Atrophy; Brain Diseases; Cerebral Cortex; Corpus Striatum; Female; Fetal Tissue Transplanta | 2001 |
Selective activation of central subtypes of the nicotinic acetylcholine receptor has opposite effects on neonatal excitotoxic brain injuries.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Animals, Newborn; Autoradiography; Brain Diseases; | 2002 |
Opposing roles for medial and central amygdala in the initiation of noradrenergic cell responses to a psychological stressor.
Topics: Amygdala; Animals; Brain Diseases; Excitatory Amino Acid Agonists; Ibotenic Acid; Male; Medulla Oblo | 2002 |
Ibotenic acid-induced calcium deposits in rat substantia nigra. Ultrastructure of their time-dependent formation.
Topics: Animals; Brain Diseases; Calcinosis; Ibotenic Acid; Male; Microscopy, Electron; Nerve Degeneration; | 1992 |
Neuroprotective synergism of 2-amino-3-phosphonoproprionate (D,L-AP3) and MK-801 against ibotenate induced brain injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Alanine; Animals; Brain; Brain Diseases; Dizocilpine Maleate; | 1992 |
A comparison of excitotoxic lesions of the basal forebrain by kainate, quinolinate, ibotenate, N-methyl-D-aspartate or quisqualate, and the effects on toxicity of 2-amino-5-phosphonovaleric acid and kynurenic acid in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Diseases; Ibotenic Acid; Kainic Acid; Kynurenic A | 1991 |
Lesions of nucleus basalis alter ChAT activity and EEG in rat frontal neocortex.
Topics: Animals; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransferase; Cortical Synchronization; Ele | 1991 |
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon.
Topics: Animals; Apomorphine; Behavior, Animal; Brain Diseases; Caudate Nucleus; Disease Models, Animal; Dys | 1990 |
Comparative effects of quisqualic and ibotenic acid-induced lesions of the substantia innominata and globus pallidus on the acquisition of a conditional visual discrimination: differential effects on cholinergic mechanisms.
Topics: Animals; Basal Ganglia; Behavior, Animal; Biomechanical Phenomena; Brain Diseases; Conditioning, Psy | 1989 |
Ibotenic acid-induced nigral lesion and limbic seizure in cats.
Topics: Animals; Brain Diseases; Cats; Electroencephalography; Female; Ibotenic Acid; Kainic Acid; Limbic Sy | 1989 |
Striatal grafts in the ibotenic acid-lesioned neostriatum: ultrastructural and immunocytochemical studies.
Topics: Animals; Brain Diseases; Cerebral Cortex; Corpus Striatum; Ibotenic Acid; Immunohistochemistry; Micr | 1988 |
Studies on host afferent inputs to fetal striatal transplants in the excitotoxically lesioned striatum.
Topics: Afferent Pathways; Animals; Benzofurans; Brain Diseases; Corpus Striatum; Female; Ibotenic Acid; Rat | 1988 |
Cortical serotonin receptor subtypes after lesion of ascending cholinergic neurones in rat.
Topics: Animals; Basal Ganglia; Brain Diseases; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fi | 1985 |
Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--I. Biochemical and anatomical observations.
Topics: Animals; Basal Ganglia; Brain Diseases; Cholinergic Fibers; Diencephalon; Embryo, Mammalian; Female; | 1985 |