ibotenic acid has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 8 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Following postoperative recovery, we recorded sleep for 6h, induced anesthesia 24h later using ketamine/diazepam or pentobarbital, and repeated sleep recordings sessions 48h and 6days later." | 3.81 | Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology. ( Ciric, J; Kalauzi, A; Lazic, K; Petrovic, J; Saponjic, J, 2015) |
| "The severity of the abnormal involuntary movements induced by L-DOPA correlated with the basal firing parameters of LC neuronal activity." | 1.37 | The locus coeruleus is directly implicated in L-DOPA-induced dyskinesia in parkinsonian rats: an electrophysiological and behavioural study. ( Aristieta, A; Cenci, MA; Miguelez, C; Ugedo, L, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumbhare, D | 1 |
| Holloway, KL | 1 |
| Baron, MS | 1 |
| Gut, NK | 1 |
| Winn, P | 1 |
| Lazic, K | 1 |
| Petrovic, J | 1 |
| Ciric, J | 1 |
| Kalauzi, A | 1 |
| Saponjic, J | 1 |
| Miguelez, C | 1 |
| Aristieta, A | 1 |
| Cenci, MA | 1 |
| Ugedo, L | 1 |
| Hou, C | 1 |
| Xue, L | 1 |
| Feng, J | 1 |
| Zhang, L | 1 |
| Wang, Y | 1 |
| Chen, L | 1 |
| Wang, T | 1 |
| Zhang, QJ | 1 |
| Liu, J | 1 |
| Luo, J | 1 |
| Kaplitt, MG | 1 |
| Fitzsimons, HL | 1 |
| Zuzga, DS | 1 |
| Liu, Y | 1 |
| Oshinsky, ML | 1 |
| During, MJ | 1 |
| Bacci, JJ | 1 |
| Kachidian, P | 1 |
| Kerkerian-Le Goff, L | 1 |
| Salin, P | 1 |
| Wright, AK | 1 |
| Arbuthnott, GW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase I Study of Subthalamic GAD Gene Transfer in Medically Refractory Parkinson's Disease Patients[NCT00195143] | Phase 1 | 12 participants | Interventional | 2003-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for ibotenic acid and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
Parkinsonism and dystonia are differentially induced by modulation of different territories in the basal ganglia.
Topics: Action Potentials; Animals; Dystonia; Electric Stimulation; Female; Globus Pallidus; Ibotenic Acid; | 2017 |
Deep brain stimulation of different pedunculopontine targets in a novel rodent model of parkinsonism.
Topics: Animals; Cell Survival; Cholinergic Neurons; Deep Brain Stimulation; Disease Models, Animal; Dopamin | 2015 |
Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology.
Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics; Animals; Brain; Diazepam; Electrocorticography; Elec | 2015 |
The locus coeruleus is directly implicated in L-DOPA-induced dyskinesia in parkinsonian rats: an electrophysiological and behavioural study.
Topics: Amphetamine; Animals; Behavior, Animal; Dyskinesias; Electrophysiology; Female; Ibotenic Acid; Levod | 2011 |
Unilateral lesion of the nigrostriatal pathway decreases the response of GABA interneurons in the dorsal raphe nucleus to 5-HT(1A) receptor stimulation in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Cell Count; Corpus Striatum; Dop | 2012 |
Subthalamic GAD gene therapy in a Parkinson's disease rat model.
Topics: Animals; Dependovirus; Disease Models, Animal; Dopamine; Electric Stimulation; Electrophysiology; ga | 2002 |
Intralaminar thalamic nuclei lesions: widespread impact on dopamine denervation-mediated cellular defects in the rat basal ganglia.
Topics: Adrenergic Agents; Animals; Autoradiography; Basal Ganglia; Carrier Proteins; Dopamine; Female; Gene | 2004 |
The influence of the subthalamic nucleus upon the damage to the dopamine system following lesions of globus pallidus in rats.
Topics: Animals; Cell Death; Cell Survival; Denervation; Dopamine; Globus Pallidus; Ibotenic Acid; Male; Ner | 2007 |