Page last updated: 2024-10-21

ibotenic acid and Atrophy

ibotenic acid has been researched along with Atrophy in 9 studies

Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.

Atrophy: Decrease in the size of a cell, tissue, organ, or multiple organs, associated with a variety of pathological conditions such as abnormal cellular changes, ischemia, malnutrition, or hormonal changes.

Research Excerpts

ExcerptRelevanceReference
"Ibotenic acid was injected into 3 parts of the lateral rat hippocampus."1.28Amyloid beta-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection. ( Hariguchi, S; Nakamura, Y; Niigawa, H; Nishimura, T; Takeda, M, 1992)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's1 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rekha, J1
Veena, LR1
Prem, N1
Kalaivani, P1
Choudhury, R1
Alladi, PA1
Agrahari, M1
Raju, TR2
Kutty, BM1
Works, SJ1
Wilson, RE1
Wellman, CL1
Chen, A1
Dimambro, N1
Clowry, GJ1
Socci, DJ1
Pert, CB1
Ruff, MR1
Arendash, GW1
Shankaranarayana Rao, BS1
Laxmi, TR1
Meti, BL1
Muñoz, A1
Lopez, A1
Caruncho, HJ1
Guerra, MJ1
Labandeira-García, JL1
Nakamura, Y1
Takeda, M1
Niigawa, H1
Hariguchi, S1
Nishimura, T1
Pasinetti, GM1
Morgan, DG1
Finch, CE1
Beal, MF1
Ferrante, RJ1
Swartz, KJ1
Kowall, NW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
NMDA-Receptor Blockade in Huntington's Chorea[NCT00001930]Phase 225 participants Interventional1999-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for ibotenic acid and Atrophy

ArticleYear
NIH-3T3 fibroblast transplants enhance host regeneration and improve spatial learning in ventral subicular lesioned rats.
    Behavioural brain research, 2011, Apr-15, Volume: 218, Issue:2

    Topics: Analysis of Variance; Animals; Atrophy; Brain-Derived Neurotrophic Factor; Fibroblast Growth Factor

2011
Age-dependent effect of cholinergic lesion on dendritic morphology in rat frontal cortex.
    Neurobiology of aging, 2004, Volume: 25, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Atrophy; Basal Nucleus of Meynert; Cholinergic Fibers; Dendrit

2004
A comparison of behavioural and histological outcomes of periventricular injection of ibotenic acid in neonatal rats at postnatal days 5 and 7.
    Brain research, 2008, Mar-27, Volume: 1201

    Topics: Animals; Animals, Newborn; Atrophy; Brain; Cerebral Cortex; Cerebral Palsy; Corpus Callosum; Disease

2008
Peptide T prevents NBM lesion-induced cortical atrophy in aged rats.
    Peptides, 1996, Volume: 17, Issue:5

    Topics: Aging; Analysis of Variance; Animals; Atrophy; Excitatory Amino Acid Agonists; Humans; Ibotenic Acid

1996
Subicular lesions cause dendritic atrophy in CA1 and CA3 pyramidal neurons of the rat hippocampus.
    Neuroscience, 2001, Volume: 102, Issue:2

    Topics: Analysis of Variance; Animals; Atrophy; Benzoxazines; Cell Count; Dendrites; Hippocampus; Ibotenic A

2001
Long-term cortical atrophy after excitotoxic striatal lesion: effects of intrastriatal fetal-striatum grafts and implications for Huntington disease.
    Journal of neuropathology and experimental neurology, 2001, Volume: 60, Issue:8

    Topics: Animals; Atrophy; Brain Diseases; Cerebral Cortex; Corpus Striatum; Female; Fetal Tissue Transplanta

2001
Amyloid beta-protein precursor deposition in rat hippocampus lesioned by ibotenic acid injection.
    Neuroscience letters, 1992, Feb-17, Volume: 136, Issue:1

    Topics: Amyloid beta-Protein Precursor; Animals; Atrophy; Denervation; Glial Fibrillary Acidic Protein; Hipp

1992
Disappearance of GAD-mRNA and tyrosine hydroxylase in substantia nigra following striatal ibotenic acid lesions: evidence for transneuronal regression.
    Experimental neurology, 1991, Volume: 112, Issue:2

    Topics: Animals; Atrophy; Corpus Striatum; Functional Laterality; Glial Fibrillary Acidic Protein; Glutamate

1991
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1991, Volume: 11, Issue:6

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atrophy; Biogenic Amines; Cerebra

1991