Page last updated: 2024-10-21

ibotenic acid and Anesthesia

ibotenic acid has been researched along with Anesthesia in 11 studies

Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" Following postoperative recovery, we recorded sleep for 6h, induced anesthesia 24h later using ketamine/diazepam or pentobarbital, and repeated sleep recordings sessions 48h and 6days later."3.81Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology. ( Ciric, J; Kalauzi, A; Lazic, K; Petrovic, J; Saponjic, J, 2015)
"Cell-selective lesions were made using ibotenic acid, and rats were later tested for changes in the dose-response relation to etomidate, propofol, alfaxalone/alfadolone, ketamine, and medetomidine delivered intravenously using a programmable infusion pump."1.56Reduced Sensitivity to Anesthetic Agents upon Lesioning the Mesopontine Tegmental Anesthesia Area in Rats Depends on Anesthetic Type. ( Baron, M; Devor, M; Minert, A, 2020)
" At early time points, NMDA receptor and NGC activation enhance descending facilitation; as time progresses, the dose-response curve of NMDA shifts to the left and descending inhibition dominates and masks any descending facilitation."1.31The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. ( Dubner, R; Ren, K; Terayama, R, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Minert, A1
Baron, M1
Devor, M1
Lazic, K1
Petrovic, J1
Ciric, J1
Kalauzi, A1
Saponjic, J1
Matsumoto, S1
Hanai, T1
Yoshioka, N1
Shimizu, N1
Sugiyama, T1
Uemura, H1
Zhuang, J1
Xu, F1
Frazier, DT1
Block, F1
Schwarz, M1
Sontag, KH1
Grecksch, G1
Bernstein, HG1
Becker, A1
Höllt, V1
Bogerts, B1
Terayama, R1
Dubner, R1
Ren, K1
Boos, R1
Müller, F1
Wässle, H1
Bouhassira, D1
Bing, Z1
Le Bars, D1
Lees, GJ1
Foster, AC1
Gill, R1
Woodruff, GN1

Other Studies

11 other studies available for ibotenic acid and Anesthesia

ArticleYear
Reduced Sensitivity to Anesthetic Agents upon Lesioning the Mesopontine Tegmental Anesthesia Area in Rats Depends on Anesthetic Type.
    Anesthesiology, 2020, Volume: 132, Issue:3

    Topics: Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Behavior, Animal; Dose-Response Relation

2020
Impact of anesthetic regimen on the respiratory pattern, EEG microstructure and sleep in the rat model of cholinergic Parkinson's disease neuropathology.
    Neuroscience, 2015, Sep-24, Volume: 304

    Topics: Adjuvants, Anesthesia; Anesthesia; Anesthetics; Animals; Brain; Diazepam; Electrocorticography; Elec

2015
Medial prefrontal cortex lesions inhibit reflex micturition in anethetized rats.
    Neuroscience research, 2006, Volume: 54, Issue:1

    Topics: Anesthesia; Animals; Excitatory Amino Acid Agonists; Ibotenic Acid; Muscle Contraction; Muscle, Smoo

2006
Hyperventilation evoked by activation of the vicinity of the caudal inferior olivary nucleus depends on the fastigial nucleus in anesthetized rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 104, Issue:5

    Topics: Anesthesia; Animals; Cerebellar Nuclei; Craniotomy; Electric Stimulation; Electrophysiology; Excitat

2008
Non-NMDA-mediated transmission of somatosensory-evoked potentials in the rat thalamus.
    Brain research bulletin, 1993, Volume: 31, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Anticonvulsants; Elec

1993
Disruption of latent inhibition in rats with postnatal hippocampal lesions.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 20, Issue:6

    Topics: Anesthesia; Animals; Apomorphine; Cognition Disorders; Conditioning, Psychological; Disease Models,

1999
The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation.
    Pain, 2002, Volume: 97, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Excitatory Amino Acid Agonis

2002
Actions of excitatory amino acids on brisk ganglion cells in the cat retina.
    Journal of neurophysiology, 1990, Volume: 64, Issue:5

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Aminobutyrates; Anesthesia; A

1990
Studies of the brain structures involved in diffuse noxious inhibitory controls: the mesencephalon.
    Journal of neurophysiology, 1990, Volume: 64, Issue:6

    Topics: Anesthesia; Animals; Electrophysiology; Ibotenic Acid; Male; Mesencephalon; Nerve Fibers; Pain; Peri

1990
Halothane anaesthesia reverses the neuroprotective effect of ketamine against ibotenic acid toxicity in the rat hippocampus.
    Brain research, 1989, Nov-20, Volume: 502, Issue:2

    Topics: Anesthesia; Animals; Cell Count; Dose-Response Relationship, Drug; Drug Interactions; Halothane; Hip

1989
Neuroprotective effects of MK-801 in vivo: selectivity and evidence for delayed degeneration mediated by NMDA receptor activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1988, Volume: 8, Issue:12

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Anesthesia; Animals; Aspartic Acid; Brain;

1988