ibotenic acid has been researched along with Allodynia in 13 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Remifentanil is a commonly used surgical analgesic." | 5.48 | The Mechanism of Hyperalgesia and Anxiety Induced by Remifentanil: Phosphorylation of GluR1 Receptors in the Anterior Cingulate Cortex. ( Huang, G; Li, S; Yu, C; Zeng, J; Zhang, C, 2018) |
| "Bilateral lesions of the RMM with ibotenic acid, a soma-selective neurotoxin, were performed to study their effects on the spontaneous pain-related behaviors and hyperalgesia, which were determined by counting the number of flinching reflex per 5 min (1 h) and by measuring paw withdrawal thermal latency (PWTL) and mechanical threshold (PWMT) to radiant heat and von-Frey filaments to both hind paws in conscious rats, respectively." | 3.72 | Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: a comparative study between formalin test and bee venom test in the rat. ( Chen, HS; Chen, J; Li, MM; Shi, J, 2003) |
| "Remifentanil is a commonly used surgical analgesic." | 1.48 | The Mechanism of Hyperalgesia and Anxiety Induced by Remifentanil: Phosphorylation of GluR1 Receptors in the Anterior Cingulate Cortex. ( Huang, G; Li, S; Yu, C; Zeng, J; Zhang, C, 2018) |
| "Patients with an orofacial pain history appear to be more susceptible to occlusal interference pain in dental practice for unknown reasons." | 1.43 | Inflammatory pain memory facilitates occlusal interference-induced masticatory muscle hyperalgesia in rats. ( Cao, Y; Ding, TT; Gan, YH; Liu, CR; Xie, QF; Xu, XX, 2016) |
| "Besides chronic stress, chronic pain is a prevalent determinant for depression." | 1.42 | The anterior cingulate cortex is a critical hub for pain-induced depression. ( Barrot, M; Barthas, F; Hugel, S; Sellmeijer, J; Waltisperger, E; Yalcin, I, 2015) |
| " However, ICV infusion of NGF induces an array of adverse events including weight loss, thermal hyperalgesia, and Schwann cell hyperplasia." | 1.32 | Intraparenchymal nerve growth factor improves behavioral deficits while minimizing the adverse effects of intracerebroventricular delivery. ( Pizzo, DP; Thal, LJ, 2004) |
| "Nonpunctate hyperalgesia was greater in lesioned rats on postoperative day 2 only; all other measures were not different." | 1.31 | Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat. ( Brennan, TJ; Gebhart, GF; Pogatzki, EM; Urban, MO, 2002) |
| " At early time points, NMDA receptor and NGC activation enhance descending facilitation; as time progresses, the dose-response curve of NMDA shifts to the left and descending inhibition dominates and masks any descending facilitation." | 1.31 | The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation. ( Dubner, R; Ren, K; Terayama, R, 2002) |
| "The persistent hyperalgesia and neuronal hyperexcitability may be mediated in part by a descending pain facilitatory system involving NGC." | 1.30 | Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation. ( Dubner, R; Ren, K; Wei, F, 1999) |
| "Since there is often an expansion of hyperalgesia to tissue adjacent, and even distant from the site of injury (secondary hyperalgesia), it is thought that this phenomenon primarily involves mechanisms of central modulation/plasticity." | 1.30 | Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat. ( Gebhart, GF; Urban, MO; Zahn, PK, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zeng, J | 1 |
| Li, S | 1 |
| Zhang, C | 1 |
| Huang, G | 1 |
| Yu, C | 1 |
| Barthas, F | 1 |
| Sellmeijer, J | 1 |
| Hugel, S | 1 |
| Waltisperger, E | 1 |
| Barrot, M | 1 |
| Yalcin, I | 1 |
| Ding, TT | 1 |
| Xu, XX | 1 |
| Cao, Y | 1 |
| Liu, CR | 1 |
| Gan, YH | 1 |
| Xie, QF | 1 |
| Chen, HS | 1 |
| Li, MM | 1 |
| Shi, J | 1 |
| Chen, J | 1 |
| Pizzo, DP | 1 |
| Thal, LJ | 1 |
| Al Amin, HA | 1 |
| Atweh, SF | 2 |
| Jabbur, SJ | 2 |
| Saadé, NE | 2 |
| Al Amin, H | 1 |
| Abdel Baki, S | 1 |
| Safieh-Garabedian, B | 1 |
| Wei, F | 1 |
| Dubner, R | 2 |
| Ren, K | 2 |
| Urban, MO | 2 |
| Zahn, PK | 1 |
| Gebhart, GF | 2 |
| Pogatzki, EM | 1 |
| Brennan, TJ | 1 |
| Terayama, R | 1 |
| Kitto, KF | 1 |
| Haley, JE | 1 |
| Wilcox, GL | 1 |
| Malmberg, AB | 1 |
| Yaksh, TL | 1 |
13 other studies available for ibotenic acid and Allodynia
| Article | Year |
|---|---|
The Mechanism of Hyperalgesia and Anxiety Induced by Remifentanil: Phosphorylation of GluR1 Receptors in the Anterior Cingulate Cortex.
Topics: Analgesics, Opioid; Animals; Anxiety; Excitatory Amino Acid Agonists; Gyrus Cinguli; Hyperalgesia; I | 2018 |
The anterior cingulate cortex is a critical hub for pain-induced depression.
Topics: Animals; Anxiety; Cerebral Cortex; Chronic Pain; Conditioning, Psychological; Depressive Disorder; D | 2015 |
Inflammatory pain memory facilitates occlusal interference-induced masticatory muscle hyperalgesia in rats.
Topics: Animals; Carrageenan; Facial Pain; Hyperalgesia; Ibotenic Acid; Inflammation; Male; Masticatory Musc | 2016 |
Supraspinal contribution to development of both tonic nociception and referred mirror hyperalgesia: a comparative study between formalin test and bee venom test in the rat.
Topics: Animals; Bee Venoms; Brain; Formaldehyde; Functional Laterality; Hindlimb; Hyperalgesia; Ibotenic Ac | 2003 |
Intraparenchymal nerve growth factor improves behavioral deficits while minimizing the adverse effects of intracerebroventricular delivery.
Topics: Animals; Avoidance Learning; Basal Nucleus of Meynert; Behavior, Animal; Cerebral Cortex; Choline O- | 2004 |
Effects of ventral hippocampal lesion on thermal and mechanical nociception in neonates and adult rats.
Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Brain Diseases; Female; Hippocampus; Hot T | 2004 |
Transient attenuation of neuropathic manifestations in rats following lesion or reversible block of the lateral thalamic somatosensory nuclei.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Cold Temperature; Excitatory Amino Acid Agonists; Fem | 2006 |
Nucleus reticularis gigantocellularis and nucleus raphe magnus in the brain stem exert opposite effects on behavioral hyperalgesia and spinal Fos protein expression after peripheral inflammation.
Topics: 5,6-Dihydroxytryptamine; Animals; Behavior, Animal; Creatinine; Freund's Adjuvant; Hindlimb; Hyperal | 1999 |
Descending facilitatory influences from the rostral medial medulla mediate secondary, but not primary hyperalgesia in the rat.
Topics: Animals; Carrageenan; Functional Laterality; Hindlimb; Hot Temperature; Hyperalgesia; Ibotenic Acid; | 1999 |
Role of the rostral medial medulla in the development of primary and secondary hyperalgesia after incision in the rat.
Topics: Animals; Behavior, Animal; Excitatory Amino Acid Agonists; Foot; Hindlimb; Hot Temperature; Hyperalg | 2002 |
The roles of NMDA receptor activation and nucleus reticularis gigantocellularis in the time-dependent changes in descending inhibition after inflammation.
Topics: 2-Amino-5-phosphonovalerate; Anesthesia; Animals; Electric Stimulation; Excitatory Amino Acid Agonis | 2002 |
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Argin | 1992 |
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Dizo | 1992 |