ibotenic acid has been researched along with Aging in 50 studies
Ibotenic Acid: A neurotoxic isoxazole (similar to KAINIC ACID and MUSCIMOL) found in AMANITA mushrooms. It causes motor depression, ataxia, and changes in mood, perceptions and feelings, and is a potent excitatory amino acid agonist.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to investigate the effects of the intrahippocampal co-injection of beta-amyloid protein1-40 (Abeta(1-40)) with ibotenic acid (Ibo) on learning and memory in normal and aging model rats, and to explore the mechanism underlying the effects of the co-injection." | 3.73 | Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats. ( Chen, QS; Li, Y; Qin, HQ; Wang, JJ, 2005) |
| "Fluoxetine has been reported to decrease the number of "mature" calbindin-positive cells in the dentate gyrus; we found this still occurred on the side of a CA3 lesion." | 1.37 | Novel control by the CA3 region of the hippocampus on neurogenesis in the dentate gyrus of the adult rat. ( Herbert, J; Liu, JX; Pinnock, SB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (10.00) | 18.7374 |
| 1990's | 28 (56.00) | 18.2507 |
| 2000's | 14 (28.00) | 29.6817 |
| 2010's | 3 (6.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Daher, I | 1 |
| Le Dieu-Lugon, B | 1 |
| Dourmap, N | 1 |
| Lecuyer, M | 1 |
| Ramet, L | 1 |
| Gomila, C | 1 |
| Ausseil, J | 1 |
| Marret, S | 3 |
| Leroux, P | 2 |
| Roy, V | 1 |
| El Mestikawy, S | 1 |
| Daumas, S | 1 |
| Gonzalez, B | 1 |
| Leroux-Nicollet, I | 1 |
| Cleren, C | 1 |
| Bailey, DJ | 1 |
| Wade, J | 1 |
| Saldanha, CJ | 1 |
| Alexander, KS | 1 |
| Brooks, JM | 1 |
| Sarter, M | 1 |
| Bruno, JP | 1 |
| Wolf, R | 1 |
| Matzke, K | 1 |
| Paelchen, K | 1 |
| Dobrowolny, H | 1 |
| Bogerts, B | 2 |
| Schwegler, H | 1 |
| Liu, JX | 1 |
| Pinnock, SB | 1 |
| Herbert, J | 1 |
| Kubo, T | 1 |
| Nishimura, S | 1 |
| Kumagae, Y | 1 |
| Kaneko, I | 1 |
| Silva-Gómez, AB | 1 |
| Bermudez, M | 1 |
| Quirion, R | 2 |
| Srivastava, LK | 1 |
| Picazo, O | 1 |
| Flores, G | 1 |
| Need, AC | 1 |
| Irvine, EE | 1 |
| Giese, KP | 1 |
| Fricker-Gates, RA | 1 |
| White, A | 1 |
| Gates, MA | 1 |
| Dunnett, SB | 1 |
| Works, SJ | 1 |
| Wilson, RE | 1 |
| Wellman, CL | 1 |
| Schmadel, S | 1 |
| Schwabe, K | 1 |
| Koch, M | 1 |
| Li, Y | 1 |
| Qin, HQ | 1 |
| Chen, QS | 1 |
| Wang, JJ | 1 |
| Marquis, JP | 1 |
| Goulet, S | 1 |
| Doré, FY | 1 |
| Laudenbach, V | 1 |
| Fontaine, RH | 1 |
| Medja, F | 1 |
| Carmeliet, P | 1 |
| Hicklin, DJ | 1 |
| Gallego, J | 1 |
| Gressens, P | 2 |
| Burke, MA | 1 |
| Apter, JR | 1 |
| Wainer, BH | 1 |
| Mufson, EJ | 1 |
| Kordower, JH | 1 |
| Callaway, EM | 1 |
| Katz, LC | 1 |
| Socci, DJ | 2 |
| Pert, CB | 1 |
| Ruff, MR | 1 |
| Arendash, GW | 4 |
| Ceresoli, G | 3 |
| Fuller, MS | 1 |
| Schwarcz, R | 3 |
| Guidetti, P | 2 |
| Evrard, P | 1 |
| Liste, I | 1 |
| Caruncho, HJ | 1 |
| Guerra, MJ | 1 |
| Labandeira-Garcia, JL | 1 |
| Frisch, C | 1 |
| Hasenöhrl, RU | 1 |
| Haas, HL | 1 |
| Weiler, HT | 1 |
| Steinbusch, HW | 1 |
| Huston, JP | 1 |
| Bernstein, HG | 1 |
| Grecksch, G | 1 |
| Becker, A | 1 |
| Höllt, V | 1 |
| Célérier, A | 1 |
| Ognard, R | 1 |
| Decorte, L | 1 |
| Beracochea, D | 1 |
| Khaing, ZZ | 1 |
| Weickert, CS | 1 |
| Weinberger, DR | 1 |
| Lipska, BK | 1 |
| Chopin, P | 1 |
| Colpaert, FC | 1 |
| Marien, M | 1 |
| Barnes, CA | 2 |
| Rao, G | 2 |
| Foster, TC | 2 |
| McNaughton, BL | 2 |
| Amenta, F | 1 |
| Martin, D | 1 |
| McNamara, JO | 1 |
| Nadler, JV | 1 |
| McDonald, JW | 1 |
| Trescher, WH | 1 |
| Johnston, MV | 1 |
| Zawia, N | 1 |
| Wecker, L | 1 |
| Michaelis, ML | 1 |
| Foster, CT | 1 |
| Jayawickreme, C | 1 |
| Baudry, M | 1 |
| Massicotte, G | 1 |
| Hauge, S | 1 |
| Miyoshi, R | 1 |
| Kito, S | 1 |
| Doudou, N | 1 |
| Nomoto, T | 1 |
| Chaudieu, I | 1 |
| Mount, H | 1 |
| Boksa, P | 1 |
| Kato, N | 1 |
| Artola, A | 1 |
| Singer, W | 1 |
| Innocenti, GM | 1 |
| Berbel, P | 1 |
| Insel, TR | 1 |
| Miller, LP | 1 |
| Gelhard, RE | 1 |
| Patel, AJ | 1 |
| Sanfeliu, C | 1 |
| Hunt, A | 1 |
| Erdö, SL | 2 |
| Wolff, JR | 2 |
| Hodges, H | 1 |
| Ribeiro, AM | 1 |
| Gray, JA | 1 |
| Marchbanks, RM | 1 |
| Millard, WJ | 1 |
| Dunn, AJ | 1 |
| Meyer, EM | 1 |
| Dudek, SM | 2 |
| Bowen, WD | 1 |
| Bear, MF | 2 |
| Hohmann, GF | 1 |
| Wenk, GL | 1 |
| Lowenstein, P | 1 |
| Brown, ME | 1 |
| Coyle, JT | 1 |
| Carpenter, P | 1 |
| Sefton, AJ | 1 |
| Dreher, B | 1 |
| Lim, WL | 1 |
50 other studies available for ibotenic acid and Aging
| Article | Year |
|---|---|
Magnesium Sulfate Prevents Neurochemical and Long-Term Behavioral Consequences of Neonatal Excitotoxic Lesions: Comparison Between Male and Female Mice.
Topics: Aging; Animals; Animals, Newborn; Brain; Calcium Channel Blockers; Disease Models, Animal; Excitator | 2017 |
Hippocampal lesions impair spatial memory performance, but not song--a developmental study of independent memory systems in the zebra finch.
Topics: Age Factors; Aging; Animals; Aromatase; Denervation; Estrogens; Female; Finches; Genes, Immediate-Ea | 2009 |
Disruption of mesolimbic regulation of prefrontal cholinergic transmission in an animal model of schizophrenia and normalization by chronic clozapine treatment.
Topics: Acetylcholine; Aging; Amphetamine; Animals; Animals, Newborn; Clozapine; Disease Models, Animal; Hip | 2009 |
Reduction of Prepulse Inhibition (PPI) after neonatal excitotoxic lesion of the ventral thalamus in pubertal and adult rats.
Topics: Age Factors; Aging; Animals; Animals, Newborn; Antipsychotic Agents; Clozapine; Disease Models, Anim | 2010 |
Novel control by the CA3 region of the hippocampus on neurogenesis in the dentate gyrus of the adult rat.
Topics: Aging; Animals; Bromodeoxyuridine; CA3 Region, Hippocampal; Calbindins; Cell Count; Cell Proliferati | 2011 |
In vivo conversion of racemized beta-amyloid ([D-Ser 26]A beta 1-40) to truncated and toxic fragments ([D-Ser 26]A beta 25-35/40) and fragment presence in the brains of Alzheimer's patients.
Topics: Aged; Aging; Alzheimer Disease; Amino Acid Isomerases; Amyloid beta-Peptides; Animals; Astrocytes; B | 2002 |
Comparative behavioral changes between male and female postpubertal rats following neonatal excitotoxic lesions of the ventral hippocampus.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Escape Reaction; Excitatory Amino Acid Agoni | 2003 |
Learning and memory impairments in Kv beta 1.1-null mutants are rescued by environmental enrichment or ageing.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Cues; Disease Models, Animal; Eating; Environmen | 2003 |
Striatal neurons in striatal grafts are derived from both post-mitotic cells and dividing progenitors.
Topics: Acetylcholinesterase; Aging; Animals; Brain Tissue Transplantation; Bromodeoxyuridine; Calbindins; C | 2004 |
Age-dependent effect of cholinergic lesion on dendritic morphology in rat frontal cortex.
Topics: Aging; Analysis of Variance; Animals; Atrophy; Basal Nucleus of Meynert; Cholinergic Fibers; Dendrit | 2004 |
Effects of neonatal excitotoxic lesions of the entorhinal cortex on cognitive functions in the adult rat.
Topics: Aging; Animals; Animals, Newborn; Apomorphine; Cognition; Conditioning, Operant; Disease Models, Ani | 2004 |
Neurochemical and behavioral effects of the intrahippocampal co-injection of beta-amyloid protein1-40 and ibotenic acid in rats.
Topics: Aging; Amyloid beta-Peptides; Animals; Avoidance Learning; Behavior, Animal; Drug Synergism; Explora | 2005 |
Neonatal lesions of the ventral hippocampus in rats lead to prefrontal cognitive deficits at two maturational stages.
Topics: Aging; Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Denervation; Disease Mode | 2006 |
Neonatal hypoxic preconditioning involves vascular endothelial growth factor.
Topics: Aging; Alanine; Animals; Animals, Newborn; Antibodies, Blocking; Brain; Excitatory Amino Acid Agonis | 2007 |
Age-related vulnerability of developing cholinergic basal forebrain neurons following excitotoxic lesions of the hippocampus.
Topics: Aging; Animals; Animals, Newborn; Choline O-Acetyltransferase; Female; Frontal Lobe; Hippocampus; Ib | 1994 |
Photostimulation using caged glutamate reveals functional circuitry in living brain slices.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Aci | 1993 |
Peptide T prevents NBM lesion-induced cortical atrophy in aged rats.
Topics: Aging; Analysis of Variance; Animals; Atrophy; Excitatory Amino Acid Agonists; Humans; Ibotenic Acid | 1996 |
Excitotoxic lesions of the rat striatum: different responses of kynurenine pathway enzymes during ontogeny.
Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Aging; Animals; Animals, Newborn; Corpus Striatum; Dioxygenas | 1996 |
Kynurenine metabolism in the rat brain in vivo. Effect of acute excitotoxic insults.
Topics: Aging; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Ibotenic Acid; Infusions, Par | 1996 |
Arrest of neuronal migration by excitatory amino acids in hamster developing brain.
Topics: 2-Amino-5-phosphonovalerate; Aging; Alanine; Animals; Animals, Newborn; Brain; Cell Differentiation; | 1996 |
Chronic nicotine treatment prevents neuronal loss in neocortex resulting from nucleus basalis lesions in young adult and aged rats.
Topics: Aging; Analysis of Variance; Animals; Cerebral Cortex; Ibotenic Acid; Male; Neurons; Neuroprotective | 1996 |
Metabolism of [5-(3)H]kynurenine in the developing rat brain in vivo: effect of intrastriatal ibotenate injections.
Topics: Aging; Animals; Brain; Corpus Striatum; Functional Laterality; Glutamate Decarboxylase; Ibotenic Aci | 1997 |
GABA(A) receptor subunit expression in intrastriatal striatal grafts comparison between normal developing striatum and developing striatal grafts.
Topics: Aging; Animals; Brain Tissue Transplantation; Corpus Striatum; Dopamine and cAMP-Regulated Phosphopr | 1997 |
Facilitation of learning after lesions of the tuberomammillary nucleus region in adult and aged rats.
Topics: Aging; Animals; Avoidance Learning; Brain Chemistry; Excitatory Amino Acid Agonists; Habituation, Ps | 1998 |
Cellular changes in rat brain areas associated with neonatal hippocampal damage.
Topics: Aging; Animals; Animals, Newborn; Brain; Brain Diseases; Calbindin 2; Excitatory Amino Acid Agonists | 1999 |
Deficits of spatial and non-spatial memory and of auditory fear conditioning following anterior thalamic lesions in mice: comparison with chronic alcohol consumption.
Topics: Acoustic Stimulation; Aging; Alcohol Amnestic Disorder; Alcoholism; Animals; Auditory Cortex; Behavi | 2000 |
Differential DNA damage in response to the neonatal and adult excitotoxic hippocampal lesion in rats.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Corpus Striatum; DNA Damage; DNA Fragmentation; Hippoca | 2000 |
Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Ag | 2002 |
Region-specific age effects on AMPA sensitivity: electrophysiological evidence for loss of synaptic contacts in hippocampal field CA1.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Electric Stimulation; Evok | 1992 |
Neuroanatomy of the cholinergic systems: modulation by pharmacological treatment.
Topics: Acetylcholine; Aging; Basal Ganglia; Choline O-Acetyltransferase; Histocytochemistry; Humans; Iboten | 1992 |
Kindling enhances sensitivity of CA3 hippocampal pyramidal cells to NMDA.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Glutamates; Glutamic Acid; | 1992 |
Susceptibility of brain to AMPA induced excitotoxicity transiently peaks during early postnatal development.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Aci | 1992 |
Basal forebrain cholinergic neurons in aged rat brain are more susceptible to ibotenate-induced degeneration than neurons in young adult brain.
Topics: Acetylcholinesterase; Aging; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Ibotenic Acid; M | 1992 |
Regulation of calcium levels in brain tissue from adult and aged rats.
Topics: Aging; Animals; Brain; Calcium; Fura-2; Ibotenic Acid; In Vitro Techniques; Male; Potassium Chloride | 1992 |
Opposite effects of phospholipase A2 on [3H]AMPA binding in adult and neonatal membranes.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Ibotenic | 1991 |
Effect of age on alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) binding sites in the rat brain studied by in vitro autoradiography.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Autoradiography; Brain; Ce | 1991 |
Transient postnatal increases in excitatory amino acid binding sites in rat ventral mesencephalon.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Membrane; Corpus Stri | 1991 |
Developmental changes in the susceptibility to long-term potentiation of neurones in rat visual cortex slices.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-me | 1991 |
Specificity of functional changes during normal brain aging.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Hippocampus; Ibotenic Acid | 1991 |
Analysis of an experimental cortical network: I). Architectonics of visual areas 17 and 18 after neonatal injections of ibotenic acid; similarities with human microgyria.
Topics: Aging; Animals; Animals, Newborn; Atropine; Brain; Cats; Epilepsy; Female; Humans; Ibotenic Acid; Mi | 1991 |
The ontogeny of excitatory amino acid receptors in rat forebrain--I. N-methyl-D-aspartate and quisqualate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Frontal Lobe; Glutamates; | 1990 |
Development and regulation of excitatory amino acid receptors involved in the release of arachidonic acid in cultured hippocampal neural cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Aci | 1990 |
Postnatal development of the excitatory amino acid system in visual cortex of the rat. Changes in ligand binding to NMDA, quisqualate and kainate receptors.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Ibotenic Acid; Male; Piper | 1990 |
Low dose tetrahydroaminoacridine (THA) improves cognitive function but does not affect brain acetylcholine in rats.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Aminoacridines; Animals; Brain; Cognition; Ethanol; Fema | 1990 |
Effects of nucleus basalis lesions on cerebral cortical concentrations of corticotropin-releasing hormone (CRH)-like immunoreactivity in the rat.
Topics: Aging; Animals; Basal Ganglia; Cerebral Cortex; Corticotropin-Releasing Hormone; Ibotenic Acid; Male | 1990 |
Transient increase in ligand binding to quisqualate and kainate sites in cerebral cortex of immature rats.
Topics: Aging; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Cerebral | 1989 |
Postnatal changes in glutamate stimulated phosphoinositide turnover in rat neocortical synaptoneurosomes.
Topics: Aging; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Ibotenic Acid; Male; Phosphatidylinositol | 1989 |
A biochemical correlate of the critical period for synaptic modification in the visual cortex.
Topics: Aging; Animals; Aspartic Acid; Carbachol; Cattle; Glutamates; Glutamic Acid; Ibotenic Acid; N-Methyl | 1989 |
Age-related recurrence of basal forebrain lesion-induced cholinergic deficits.
Topics: Age Factors; Aging; Alzheimer Disease; Animals; Cerebral Cortex; Choline O-Acetyltransferase; Cholin | 1987 |
Role of target tissue in regulating the development of retinal ganglion cells in the albino rat: effects of kainate lesions in the superior colliculus.
Topics: Aging; Animals; Cell Count; Horseradish Peroxidase; Ibotenic Acid; Kainic Acid; Microinjections; Ner | 1986 |